Works Published in 2005
Displaying works 1 - 20 of 113 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2005 journal article
Development of beta-lapachone prodrugs for therapy against human cancer cells with elevated NAD(P)H:quinone oxidoreductase 1 levels.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research.
MeSH headings : Cell Division / drug effects; Cell Line, Tumor; Cell Survival / drug effects; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Magnetic Resonance Spectroscopy; NAD(P)H Dehydrogenase (Quinone) / metabolism; Naphthoquinones / chemistry; Naphthoquinones / pharmacology; Neoplasms / drug therapy; Neoplasms / enzymology; Neoplasms / pathology; Prodrugs / chemical synthesis; Prodrugs / chemistry; Prodrugs / pharmacology; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Structure-Activity Relationship
clincancerres.aacrjournals.org (publisher PDF)
Source: ORCID
Added: June 25, 2021
2005 journal article
752. Equine Infectious Anemia Virus Pseudotyped with the Vesicular Stomatitis Virus G-Protein, Preferentially Targets Neural Precursors in the Adult Mouse Brain
Molecular Therapy, 11(Supplement 1), S292.
TL;DR:
The preferential targeting of GFAP+ astrocytes in the SVZ by the EIAV lentivirus is potentially useful for the molecular manipulation of these stem cells.
(via Semantic Scholar)
Source: Crossref
Added: December 29, 2020
2005 journal article
Expert's opinion on potential role of epithelial cells in pathogenesis of organ dysfunction
Journal of Organ Dysfunction, 1(1), 24–25.
Source: Crossref
Added: December 29, 2020
2005 journal article
Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension
British Journal of Pharmacology, 146(7), 1010–1018.
author keywords: Rho proteins; signal transduction; phosphodiesterase; smooth muscle
MeSH headings : 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / analogs & derivatives; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / therapeutic use; Actins / metabolism; Animals; Carrier Proteins / metabolism; Chronic Disease; Cytoskeleton / drug effects; Guanine Nucleotide Dissociation Inhibitors / physiology; Hypertension, Pulmonary / drug therapy; Hypertension, Pulmonary / enzymology; Hypertension, Pulmonary / etiology; Hypoxia / complications; Male; Phosphodiesterase Inhibitors / pharmacology; Phosphoprotein Phosphatases / metabolism; Phosphorylation; Piperazines / pharmacology; Piperazines / therapeutic use; Protein Phosphatase 1; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; rhoA GTP-Binding Protein / antagonists & inhibitors
TL;DR:
It is proposed that sildenafil inhibits RhoA/Rho kinase‐dependent functions in pulmonary artery through enhanced RHoA phosphorylation and cytosolic sequestration by GDI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
51 PHENOTYPIC VARIATION IN CLONED SWINE IS CORRECTED IN THE F1 GENERATION
Reproduction, Fertility and Development, 17(2), 175.
TL;DR:
The hypothesis that offspring of clones are to all intent and purposes indistinguishable from offspring of naturally bred animals, and as such there should not be any increased risks associated with consumption of products from these animals, is strongly supported.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Demonstration of toxicity to fish and to mammalian cells by Pfiesteria species: Comparison of assay methods and strains
Proceedings of the National Academy of Sciences, 102(9), 3471–3476.
author keywords: toxigenic dinoflagellates; Pfiesteria piscicida; Pfiesteria shumwayae
MeSH headings : Animals; Bacterial Toxins / toxicity; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Fishes / microbiology; Magnetic Resonance Spectroscopy; Mammals / microbiology; Pfiesteria piscicida / pathogenicity; Polymerase Chain Reaction
TL;DR:
The data show the importance of testing multiple strains when assessing the potential for toxicity at the genus or species level, using appropriate culturing techniques and assays.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Maternal–fetal Distribution of Manganese in the Rat Following Inhalation Exposure to Manganese Sulfate
NeuroToxicology, 26(4), 625–632.
author keywords: manganese; inhalation; rat; pregnancy
MeSH headings : Animals; Body Burden; Female; Fetus / metabolism; Inhalation Exposure; Male; Manganese Compounds / administration & dosage; Manganese Compounds / pharmacokinetics; Maternal-Fetal Exchange / physiology; Organ Size / drug effects; Pregnancy; Rats; Sulfates / administration & dosage; Sulfates / pharmacokinetics; Tissue Distribution
TL;DR:
The results of this study demonstrate that the placenta partially sequesters inhaled manganese, thereby limiting exposure to the fetus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Manganese Dosimetry: Species Differences and Implications for Neurotoxicity
Critical Reviews in Toxicology, 35(1), 1–32.
author keywords: biomarkers; brain; manganese; metabolism; neurotoxicity; pharmacokinetics
MeSH headings : Absorption; Adult; Blood-Brain Barrier; Central Nervous System / drug effects; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Inhalation Exposure; Male; Manganese / administration & dosage; Manganese / adverse effects; Manganese / pharmacokinetics; Maternal-Fetal Exchange; Pregnancy; Public Health; Risk Assessment
Source: Crossref
Added: February 24, 2020
2005 journal article
GeneKeyDB: A lightweight, gene-centric, relational database to support data mining environments
BMC Bioinformatics, 6(1), 72.
MeSH headings : Algorithms; Animals; Computational Biology / instrumentation; Computational Biology / methods; Computer Graphics; Computers; Data Interpretation, Statistical; Database Management Systems; Databases as Topic; Databases, Factual; Databases, Genetic; Databases, Protein; Genomics; Humans; Information Storage and Retrieval; Internet; Programming Languages; Software; Software Design; Systems Integration; User-Computer Interface
TL;DR:
GeneKeyDB is a gene-centered relational database developed to enhance data mining in biological data sets and can enable analysis tools and users to manipulate the intersections, unions, and differences among different data sets.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2019
2005 journal article
The HemoCueR for point-of-care hemoglobin measurement and packed cell volume estimation in cats
Journal of Veterinary Emergency and Critical Care, 15(1), 22–25.
author keywords: azidemethemoglobin; cyanmethemoglobin; feline; hemoglobinometer; PCV; photometric methods
TL;DR:
Hemoglobin concentration measured by the HemoCue s was indistinguishable from the HbCY method in feline blood over a wide range of hemoglobin concentrations, demonstrating that in cats PCV 5 3.1HbHQ.
(via Semantic Scholar)
Source: Crossref
Added: July 27, 2019
2005 journal article
Veterinary Students and Non-academic Stressors
Journal of Veterinary Medical Education, 32(2), 193–200.
MeSH headings : Animals; Colorado / epidemiology; Education, Veterinary; Female; Gender Identity; Humans; Male; Risk Factors; Schools, Veterinary; Stress, Psychological / epidemiology; Stress, Psychological / etiology; Stress, Psychological / prevention & control; Students / psychology; Substance-Related Disorders; Surveys and Questionnaires
TL;DR:
Investigation of the levels and causes of stress among, and the frequency and type of coping strategies used by, fourth- and fifth-year students at Murdoch University in Western Australia found that academic stressors and perceived responsibilities attached to moving into practical or professional areas figured strongly and were associated with higher levels of stress in the students.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: July 21, 2019
2005 journal article
Developing and Implementing an Assessment Method to Evaluate a Virtual Canine Anatomy Program
Journal of Veterinary Medical Education, 32(2), 249–254.
MeSH headings : Anatomy / education; Animals; Colorado; Dogs / anatomy & histology; Education, Veterinary / standards; Educational Measurement; Focus Groups; Humans; Program Evaluation; User-Computer Interface
TL;DR:
A computer-based anatomy program, Virtual Canine Anatomy: The Head, was incorporated into a first-year veterinary dissection laboratory two years ago to address challenges inherent in the traditional pedagogical approach and suggest positive student and faculty attitudes toward the program.
(via Semantic Scholar)
Source: Crossref
Added: July 21, 2019
2005 journal article
Web-Based Technology: Its Effects on Small Group “Problem-Based Learning” Interactions in a Professional Veterinary Medical Program
Journal of Veterinary Medical Education, 32(1), 86–92.
MeSH headings : Computer-Assisted Instruction; Education, Veterinary; Educational Technology; Faculty, Medical; Humans; Internet; Online Systems; Problem-Based Learning; Program Evaluation; Teaching; User-Computer Interface
TL;DR:
No direct evidence was found to suggest that use of WebCT affected teaching behaviors (e.g., student-centered vs. teacher-centered instruction), but all facilitators showed a moderate increase in comfort with the technology during the semester, and one participant showed remarkable gains in technology skills.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(OpenAlex)
Source: Crossref
Added: July 21, 2019
2005 journal article
Response of a veterinary college to career development needs identified in the KPMG LLP study and the executive summary of the Brakke study: a combined MBA/DVM program, business certificate program, and curricular modifications
Journal of the American Veterinary Medical Association, 226(7), 1070–1076.
MeSH headings : Career Mobility; Clinical Competence; Commerce; Curriculum; Education, Veterinary; Humans; Practice Management; Professional Competence; Schools, Veterinary / standards; Schools, Veterinary / trends; Students / psychology; United States; Veterinarians / psychology; Veterinary Medicine
TL;DR:
CSU CVMBS has undertaken a major initiative to improve the veterinary practice management and business skills training of veterinary students by offering a variety of options to gain this knowledge: a combined MBA/DVM degree program, a Business Certificate Program for Health Professions, and core curriculum courses.
(via Semantic Scholar)
Source: Crossref
Added: July 21, 2019
2005 journal article
Isolation and Characterization of a Putative Intestinal Stem Cell Fraction From Mouse Jejunum
Gastroenterology, 129(5), 1567–1580.
MeSH headings : Age Factors; Animals; Animals, Newborn; Antigens, CD34 / metabolism; Biomarkers; Cell Fractionation; Cell Separation; Cell Survival; Cells, Cultured; Intestinal Mucosa / cytology; Jejunum / cytology; Leukocyte Common Antigens / metabolism; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Proto-Oncogene Proteins c-kit / metabolism; RNA, Messenger / analysis; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism; Stem Cells / cytology; Stem Cells / metabolism
TL;DR:
The CD45-negative SP fraction, although not pure, represents the successful isolation of a viable population significantly enriched in small intestinal epithelial stem cells.
(via Semantic Scholar)
Source: Crossref
Added: July 20, 2019
2005 journal article
In situ 13C DEPT-MRI as a tool to spatially resolve chemical conversion and selectivity of a heterogeneous catalytic reaction occurring in a fixed-bed reactor.
Chemical Communications (Cambridge, England), (21), 2741–2743.
Contributors: B. Akpa* , M. Mantle*, A. Sederman * & L. Gladden *
TL;DR:
The distortionless enhancement by polarisation transfer (DEPT) nuclear magnetic resonance (NMR) technique, combined with magnetic resonance imaging (MRI), has been used to provide the first in situ spatially-resolved and quantitative measurement of chemical conversion and selectivity within a fixed-bed reactor using natural abundance 13C NMR.
(via Semantic Scholar)
Source: ORCID
Added: May 18, 2019
2005 chapter
Antimicrobial Drug Therapy
In S. J. Ettinger & E. C. Feldman (Eds.), Textbook of Veterinary Internal Medicine: Diseases of the Dog and Cat (6th ed., pp. 498–502). St. Louis, Missouri: Elsevier Saunders.
Ed(s): S. Ettinger & E. Feldman
Source: NC State University Libraries
Added: April 17, 2019
2005 journal article
Drug compounding for veterinary patients
AAPS Journal (American Association of Pharmaceutical Scientists), 7(2), E281–287.
Source: NC State University Libraries
Added: April 13, 2019
2005 chapter
Veterinary Pharmaceuticals: Factors Influencing their Development and Use
In Encyclopedia of Pharmaceutical Technology. Taylor & Francis.
Source: NC State University Libraries
Added: April 13, 2019
2005 book
Small Animal Medicine: The Year in Small Animal Medicine
(Vol. 1). Blackwell Publishing.
Ed(s): J. Maddison & M. Papich
Source: NC State University Libraries
Added: March 29, 2019
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