Works Published in 2011
Displaying works 41 - 60 of 123 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
A high ratio of dietary n-6/n-3 polyunsaturated fatty acids is associated with increased risk of prostate cancer
Nutrition Research, 31(1), 1–8.
author keywords: Dietary fatty acids; Prostate cancer; Veterans; Race; Case control
MeSH headings : Aged; Case-Control Studies; Confidence Intervals; Diet; Dietary Fats, Unsaturated / metabolism; Fatty Acids, Omega-3 / metabolism; Fatty Acids, Omega-6 / metabolism; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Prostatic Neoplasms / metabolism; Risk Factors; Surveys and Questionnaires
TL;DR:
It is suggested that a high dietary ratio of n-6/n-3 fatty acids may increase the risk of overall prostate cancer among white men and possibly increase therisk of high-grade prostate canceramong all men.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
1613 GENETIC VARIATION IN OBESITY-RELATED GENES ADBR2, ADBR3, GHRL, HSD11B1, AND SHC1 AND RISK OF PROSTATE CANCER: A VA CASE-CONTROL STUDY
Journal of Urology, 185(4S).
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
605 COMBINATION OF ADH GENE POLYMORPHISM AND ALCOHOL CONSUMPTION CONSTITUTES A NOVEL PROSTATE CANCER RISK FACTOR IN AFRICAN-AMERICAN MEN
Journal of Urology, 185(4S).
TL;DR:
Preliminary findings suggest the ADH1B*3 variant allele and alcohol intake is a novel gene-environment interaction for PC risk, nearly unique to AAM.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
The association of diabetes mellitus and high-grade prostate cancer in a multiethnic biopsy series
Cancer Causes & Control, 22(7), 977–983.
author keywords: Prostatic neoplasm; Prostate-specific antigen; Diabetes Mellitus; Incidence; Epidemiology; Case-control studies; Obesity; Population groups; Ethnic groups; Continental population groups; Male
MeSH headings : Aged; Biopsy; Body Mass Index; Carcinoma / complications; Carcinoma / epidemiology; Carcinoma / ethnology; Carcinoma / pathology; Diabetes Complications / epidemiology; Diabetes Complications / ethnology; Diabetes Mellitus / epidemiology; Diabetes Mellitus / ethnology; Ethnicity / statistics & numerical data; Humans; Male; Middle Aged; Obesity / complications; Obesity / epidemiology; Obesity / ethnology; Prostatic Neoplasms / complications; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / ethnology; Prostatic Neoplasms / pathology; Retrospective Studies
TL;DR:
The association of diabetes mellitus with risk of prostate cancer and cancer grade among men undergoing prostate biopsy is analyzed and how obesity and race modify these associations is analyzed to suggest the effect of DM on high-grade prostate cancer is modified by race and obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2
Nature Genetics, 43(6), 539–546.
MeSH headings : Adolescent; Adult; Child; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 20; Cystic Fibrosis / genetics; Female; Genetic Linkage; Genome-Wide Association Study; Humans; Lung Diseases / genetics; Male; Phenotype; Quantitative Trait Loci
TL;DR:
The authors' findings provide insight into the causes of variation in lung disease severity in cystic fibrosis and suggest new therapeutic targets for this life-limiting disorder.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
MicroRNA expression in the livers of inbred mice
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 714(1-2), 126–133.
author keywords: MicroRNA; Liver; Mouse; Gene expression
MeSH headings : Animals; Gene Expression; Liver / metabolism; Mice; Mice, Inbred Strains / genetics; MicroRNAs / metabolism; Polymorphism, Single Nucleotide
TL;DR:
The stability of mouse liver miRNA expression in a genetically diverse population suggests that treatment-induced disruptions in liver mi RNA expression may indicate an important mechanism for the disturbance of normal liver function, and may prove to be a useful genetic background-independent biomarker of toxicant effect.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis Genetic modifier studies
Pediatric Pulmonology, 46(9), 857–869.
author keywords: forced expiratory volume; age effects; severity of illness index
MeSH headings : Adolescent; Child; Chronic Disease; Clinical Trials as Topic; Cystic Fibrosis / genetics; Cystic Fibrosis / mortality; Female; Humans; Male; Multicenter Studies as Topic; Phenotype; Respiratory Function Tests; Severity of Illness Index; Survival Analysis
TL;DR:
Genetic studies of lung disease in cystic fibrosis are hampered by the lack of a severity measure that accounts for chronic disease progression and mortality attrition and combining analyses across studies requires common phenotypes that are robust to study design and patient ascertainment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
Assessment of bisphenol A released from reusable plastic, aluminium and stainless steel water bottles
Chemosphere, 85(6), 943–947.
Contributors: J. Cooper*, E. Kendig* & S. Belcher*
author keywords: Bisphenol A; Copolyester; Epoxy resins; Endocrine disrupting chemicals; Polycarbonate; Water bottles
MeSH headings : Aluminum / chemistry; Benzhydryl Compounds; Endocrine Disruptors / analysis; Endocrine Disruptors / chemistry; Food Packaging / methods; Phenols / analysis; Phenols / chemistry; Plastics / chemistry; Recycling; Stainless Steel / chemistry; Water / chemistry
TL;DR:
The results from this study demonstrate that when used according to manufacturers' recommendations reusable water bottles constructed from "BPA-free" alternative materials are suitable for consumption of beverages free of BPA contamination.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2011 journal article
Rac/JNK/dub regulates intercellular adhesive dynamics during gut morphogenesis
Developmental Biology, 356(1), 141.
TL;DR:
It is shown that the activity of Jun N-terminal kinase (JNK) is required for Xenopus gut morphogenesis, and data suggest that a Rac/JNK/dub pathway orchestrates tissue-elongating endoderm cell rearrangements during gut Morphogenesis by regulating intercellular adhesive dynamics.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Control of skin cancer by the circadian rhythm
Proceedings of the National Academy of Sciences, 108(46), 18790–18795.
Contributors: S. Gaddameedhi* , C. Selby, W. Kaufmann*, R. Smart n & A. Sancar *
author keywords: circadian clock; cryptochrome; sunbathing; tanning salons
MeSH headings : Animals; Carcinoma, Squamous Cell / etiology; Carcinoma, Squamous Cell / physiopathology; Circadian Rhythm / physiology; DNA Damage; DNA Repair; Disease Models, Animal; Humans; Immunohistochemistry / methods; Mice; Mice, Inbred C57BL; Mice, Transgenic; Skin / radiation effects; Skin Neoplasms / etiology; Skin Neoplasms / physiopathology; Sunlight; Time Factors; Xeroderma Pigmentosum Group A Protein / biosynthesis; Xeroderma Pigmentosum Group A Protein / genetics
TL;DR:
It is concluded that time of day of exposure to UVR is a contributing factor to its carcinogenicity in mice, and possibly in humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: February 24, 2020
2011 journal article
A powerful and flexible approach to the analysis of RNA sequence count data
Bioinformatics, 27(19), 2672–2678.
Source: ORCID
Added: October 7, 2019
2011 journal article
seeQTL: a searchable database for human eQTLs
Bioinformatics, 28(3), 451–452.
Source: ORCID
Added: October 7, 2019
2011 journal article
Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer
Pharmacogenetics and Genomics, 21(10), 615–623.
Contributors: S. Koutros *, G. Andreotti *, S. Berndt *, K. Hughes Barry *, J. Lubin*, J. Hoppin* , F. Kamel*, D. Sandler *
author keywords: interaction; pesticides; prostate cancer; single nucleotide polymorphism; xenobiotic-metabolizing enzymes
MeSH headings : Alleles; Epoxide Hydrolases / genetics; Genetic Association Studies; Glutamate-Cysteine Ligase / genetics; Humans; Logistic Models; Male; Occupational Exposure; Oxidative Stress / genetics; Peroxidase / genetics; Pesticides / adverse effects; Polymorphism, Single Nucleotide; Prostatic Neoplasms / genetics; Risk Factors; Thioredoxin Reductase 2 / genetics; Xenobiotics / metabolism
TL;DR:
The number of observed interactions in XMEs was comparable with the number expected by chance alone, and several pesticide–SNP interactions in oxidative stress and phase I/II enzyme genes and risk of prostate cancer were observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Mortality in the agricultural health study, 1993-2007
American Journal of Epidemiology, 173(1), 71–83.
Contributors: J. Waggoner*, G. Kullman, P. Henneberger, D. Umbach, A. Blair, M. Alavanja, F. Kamel, C. Lynch
author keywords: agriculture; healthy worker effect; mortality; neoplasms; pesticides; wounds and injuries
MeSH headings : Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / mortality; Cause of Death / trends; Female; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Retrospective Studies; Survival Rate / trends
TL;DR:
Using data from the Agricultural Health Study, a cohort of 89,656 pesticide applicators and their spouses in North Carolina and Iowa, standardized mortality ratios (SMRs) were computed comparing deaths from time of the enrollment through 2007 to state-specific rates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2011 journal article
Neurologic Symptoms Associated With Raising Poultry and Swine Among Participants in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 53(2), 190–195.
Contributors: M. Davis *, F. Kamel*, J. Hoppin* , M. Alavanja*, L. Freeman*, G. Gray *, K. Nelson*, E. Silbergeld*
MeSH headings : Adult; Agricultural Workers' Diseases / diagnosis; Agricultural Workers' Diseases / epidemiology; Alcohol Drinking / epidemiology; Animals; Female; Guillain-Barre Syndrome / epidemiology; Humans; Hypesthesia / diagnosis; Hypesthesia / epidemiology; Male; Middle Aged; Muscle Weakness / diagnosis; Muscle Weakness / epidemiology; Nervous System Diseases / diagnosis; Nervous System Diseases / epidemiology; Poultry; Prevalence; Smoking / epidemiology; Swine
TL;DR:
Occupational contact with live poultry or swine, potentially related to C. jejuni exposure, was associated with increased reporting of GBS-like symptoms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Questionnaire Predictors of Atopy in a US Population Sample: Findings From the National Health and Nutrition Examination Survey, 2005-2006
American Journal of Epidemiology, 173(5), 544–552.
Contributors: J. Hoppin* , R. Jaramillo *, P. Salo*, D. Sandler *, S. London * & D. Zeldin *
author keywords: hypersensitivity; immunoglobulin E; questionnaires; sensitivity and specificity
MeSH headings : Adolescent; Adult; Biomarkers / blood; Child; Child, Preschool; Eczema / epidemiology; Eczema / immunology; Female; Health Surveys / statistics & numerical data; Humans; Hypersensitivity / epidemiology; Hypersensitivity / immunology; Hypersensitivity, Immediate / epidemiology; Immunoglobulin E / blood; Immunologic Factors / blood; Infant; Male; Middle Aged; Nutrition Surveys / statistics & numerical data; Predictive Value of Tests; Rhinitis, Allergic, Seasonal / epidemiology; Sampling Studies; Sensitivity and Specificity; Surveys and Questionnaires; United States / epidemiology
TL;DR:
To assess questionnaires' ability to predict biochemical measures of atopy, the authors used data on 5 allergic conditions and serum-specific immunoglobulin E (IgE) levels from the 2005-2006 National Health and Nutrition Examination Survey to identify participants found to be atopic by biochemical measures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Rotenone, Paraquat, and Parkinson’s Disease
Environmental Health Perspectives, 119(6), 866–872.
Contributors: C. Tanner *, F. Kame*, G. Ross*, J. Hoppin* , S. Goldman*, M. Korell*, C. Marras *, G. Bhudhikanok*
author keywords: aging; agricultural epidemiology; environmental epidemiology; epidemiology; fungicides; herbicides; insecticides; persistent organic pollutants; pesticides
MeSH headings : Aged; Case-Control Studies; Female; Herbicides / toxicity; Humans; Insecticides / toxicity; Iowa / epidemiology; Male; Middle Aged; Mitochondria / metabolism; North Carolina / epidemiology; Occupational Exposure; Oxidative Stress; Paraquat / toxicity; Parkinson Disease / epidemiology; Parkinson Disease / etiology; Parkinsonian Disorders / epidemiology; Parkinsonian Disorders / etiology; Rotenone / toxicity
TL;DR:
PD was positively associated with two groups of pesticides defined by mechanisms implicated experimentally—those that impair mitochondrial function and those that increase oxidative stress—supporting a role for these mechanisms in PD pathophysiology.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Job Activities and Respiratory Symptoms Among Farmworkers in North Carolina
Archives of Environmental & Occupational Health, 66(3), 178–182.
Contributors: M. Mirabelli *, J. Hoppin* , A. Chatterjee *, S. Isom *, H. Chen *, J. Grzywacz *, T. Howard *, S. Quandt *, Q. Vallejos*, T. Arcury *
author keywords: agriculture; asthma; epidemiology; occupational lung disease; respiratory diseases
MeSH headings : Age Factors; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agriculture / statistics & numerical data; Female; Humans; Logistic Models; Male; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Prevalence; Respiratory Sounds; Respiratory Tract Diseases / epidemiology; Respiratory Tract Diseases / etiology; Smoking / adverse effects; Smoking / epidemiology; Surveys and Questionnaires
TL;DR:
Though not statistically significant, the odds of wheezing were elevated for individuals who reported performing tobacco-related work in the last 3 days and the odds were decreased among individuals who report harvesting activities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Impact of pesticide exposure misclassification on estimates of relative risks in the Agricultural Health Study
Occupational and Environmental Medicine, 68(7), 537–541.
Contributors: A. Blair*, K. Thomas *, J. Coble*, D. Sandler *, C. Hines*, C. Lynch *, C. Knott*, M. Purdue *
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / urine; Agriculture / statistics & numerical data; Algorithms; Biomarkers / urine; Environmental Monitoring / methods; Humans; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupational Exposure / statistics & numerical data; Pesticides / toxicity; Prospective Studies; Pyridones / urine; Risk Assessment / methods
TL;DR:
Findings indicate that a priori expert-derived algorithm scores were more closely related to measured urinary levels than individual exposure determinants evaluated here, which indicates that non-differential misclassification of exposure would bias relative risk estimates in the AHS towards the null and diminish study power.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Atrazine and Cancer Incidence Among Pesticide Applicators in the Agricultural Health Study (1994–2007)
Environmental Health Perspectives, 119(9), 1253–1259.
Contributors: L. Beane Freeman*, J. Rusiecki *, J. Hoppin* , J. Lubin*, S. Koutros *, G. Andreotti *, S. Zahm*, C. Hines*
author keywords: agriculture; atrazine; cancer; cohort study; epidemiology; pesticide
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Atrazine / toxicity; Carcinogens / toxicity; Cohort Studies; Confidence Intervals; Female; Herbicides / adverse effects; Humans; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Odds Ratio; Poisson Distribution; Prospective Studies; Surveys and Questionnaires; Thyroid Neoplasms / chemically induced; Thyroid Neoplasms / epidemiology
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
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