Translational Regenerative Medicine

NC State

Works Published in 2014

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Displaying all 18 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2014 journal article

CD90/Thy-1-negative cardiosphere-derived cells exhibit augmented regenerative potency in humans and mice with myocardial infarction

Journal of the American Heart Association, 3(5), 001260.

By: K. Cheng, A. Ibrahim, M. Hensley, B. Sun, W. Liu, R. Smith, E. Marban

Source: NC State University Libraries
Added: April 24, 2021

2014 journal article

Functional properties of bone marrow-derived MSC-based engineered cartilage are unstable with very long-term in vitro culture

Journal of Biomechanics, 47(9), 2173–2182.

By: M. Farrell, M. Fisher*, A. Huang, J. Shin, K. Farrell & R. Mauck

author keywords: Mesenchymal stem cells; Chondrogenesis; Three-dimensional culture; Cartilage; Mechanical properties
MeSH headings : Animals; Bone Marrow Cells / cytology; Cartilage / cytology; Cartilage / metabolism; Cattle; Cell Survival; Cells, Cultured; Chondrocytes / cytology; Chondrogenesis; Femur; Glycosaminoglycans / metabolism; Hydrogels; Mesenchymal Stem Cells / cytology; Sepharose; Tissue Engineering / methods; Tissue Scaffolds
Source: Crossref
Added: December 19, 2020

2014 journal article

Maximizing cartilage formation and integration via a trajectory-based tissue engineering approach

Biomaterials, 35(7), 2140–2148.

By: M. Fisher*, E. Henning*, N. Söegaard*, G. Dodge*, D. Steinberg* & R. Mauck*

author keywords: Tissue engineering; Hyaluronic acid; Hydrogels; Cartilage; Integration; Maturation
MeSH headings : Animals; Cartilage / growth & development; Cattle; Tissue Engineering
Source: Crossref
Added: December 19, 2020

2014 journal article

Importance of Cell-Cell Contact in the Therapeutic Benefits of Cardiosphere-Derived Cells

STEM CELLS, 32(9), 2397–2406.

By: Y. Xie*, A. Ibrahim, K. Cheng*, Z. Wu*, W. Liang, K. Malliaras, B. Sun, W. Liu ...

author keywords: Cardiosphere-derived cells; Cardiomyocyte; Proliferation; Paracrine factors; Cell-cell communication; beta 1 integrin
MeSH headings : Animals; Cell Communication / physiology; Cell Differentiation / physiology; Cells, Cultured; Humans; Integrin beta1 / metabolism; Male; Mice; Mice, SCID; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats
Source: Crossref
Added: August 28, 2020

2014 journal article

5 DISRUPTION OF THE HIGH MOBILITY GROUP AT-HOOK 2 (HMGA2) GENE IN SWINE REDUCES POSTNATAL GROWTH

Reproduction, Fertility and Development, 26(1), 117.

By: J. Chung n, X. Zhang n, B. Colins n, K. Howard, S. Simpson n, C. Salmon, S. Koh n, R. Sper n, C. Byrd, J. Piedrahita n

Source: Crossref
Added: February 24, 2020

2014 journal article

The Influence of MgO Nanoparticles on the Osseointegration of Polycaprolactone - Sodium Alginate Hydrogel Interfaces

British Journal of Applied Science & Technology, 4(1), 79–88.

By: M. Khandaker, M. Vaughan & B. Starly

Ed(s): M. Vimalan

Sources: Crossref, ORCID
Added: January 5, 2020

2014 journal article

Cardiosphere-derived Cells Stimulate Cardiomyocyte Proliferation via β1 Integrin Signaling

Stem Cells, 32, 2397–2406.

By: Y. Xie, A. Ibrahim, K. Cheng, K. Malliaras, D. Shen, B. Sun, H. Cho, M. Human

Source: NC State University Libraries
Added: July 28, 2019

2014 journal article

Intracoronary Cardiosphere-Derived Cells After Myocardial Infarction

Journal of the American College of Cardiology, 63(2), 110–122.

By: K. Malliaras, R. Makkar, R. Smith, K. Cheng*, E. Wu*, R. Bonow*, L. Marbán, A. Mendizabal* ...

author keywords: cardiosphere-derived cells; myocardial infarction; myocardial regeneration
MeSH headings : Aged; Biopsy; Coronary Vessels; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Ventricles / pathology; Heart Ventricles / physiopathology; Humans; Injections, Intra-Arterial; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Infarction / complications; Myocardial Infarction / physiopathology; Myocardial Infarction / surgery; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Recovery of Function; Stem Cell Transplantation / methods; Time Factors; Transplantation, Autologous; Treatment Outcome; Ventricular Dysfunction, Left / etiology; Ventricular Dysfunction, Left / physiopathology; Ventricular Dysfunction, Left / surgery; Ventricular Function, Left / physiology
Source: Crossref
Added: July 21, 2019

2014 journal article

Human Cardiosphere-Derived Cells From Advanced Heart Failure Patients Exhibit Augmented Functional Potency in Myocardial Repair

JACC: Heart Failure, 2(1), 49–61.

By: K. Cheng*, K. Malliaras, R. Smith, D. Shen*, B. Sun, A. Blusztajn*, Y. Xie, A. Ibrahim ...

author keywords: cardiosphere-derived cells; heart failure; myocardial infarction; patient characteristics; stromal cell-derived factor 1
MeSH headings : Adult; Aged; Animals; Cardiomyopathies / physiopathology; Extracellular Matrix; Female; Graft Survival / physiology; Heart / physiology; Heart Failure / physiopathology; Humans; Intercellular Signaling Peptides and Proteins / metabolism; Male; Mice, SCID; Middle Aged; Myocardial Infarction / physiopathology; Myocytes, Cardiac / physiology; Neovascularization, Physiologic / physiology; Oxidative Stress / physiology; Regeneration / physiology; Stem Cell Transplantation / methods; Stem Cells / physiology; Transplantation, Autologous
Source: Crossref
Added: July 21, 2019

2014 journal article

Engineered Electrical Conduction Tract Restores Conduction in Complete Heart Block

Journal of the American College of Cardiology, 64(24), 2575–2585.

By: E. Cingolani, V. Ionta*, K. Cheng*, A. Giacomello*, H. Cho & E. Marbán

author keywords: arrhythmias; cardiac tissue engineering; gap junctions; heart conduction system
MeSH headings : Animals; Atrioventricular Block / pathology; Atrioventricular Block / physiopathology; Atrioventricular Block / surgery; Cell Transplantation / methods; Cells, Cultured; Electromagnetic Fields; Heart Conduction System / pathology; Heart Conduction System / physiopathology; Heart Conduction System / surgery; Heart Ventricles / pathology; Immunoconjugates / pharmacology; In Vitro Techniques; Magnets; Models, Cardiovascular; Myocytes, Cardiac / pathology; Rats; Rats, Sprague-Dawley; Sarcoglycans / immunology; Sarcoglycans / pharmacology; Tissue Engineering
Source: Crossref
Added: July 21, 2019

2014 journal article

Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy

European Heart Journal, 36(12), 751–762.

By: M. Aminzadeh*, E. Tseliou*, B. Sun*, K. Cheng*, K. Malliaras*, R. Makkar*, E. Marban*

author keywords: Cardiomyopathy; Heart failure; Cell transplantation
MeSH headings : Animals; Apoptosis / physiology; CREB-Binding Protein / metabolism; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / physiopathology; Cardiomyopathy, Dilated / therapy; Cell Differentiation; Cell Lineage; Disease Models, Animal; Doxorubicin / pharmacology; Fibrosis; Graft Survival; Heart Failure / pathology; Heart Failure / physiopathology; Heart Failure / therapy; Injections, Intralesional; Male; Mice, Transgenic; Myocarditis / physiopathology; Myocardium / pathology; Myocytes, Cardiac / transplantation; Oxidative Stress / physiology; Protein Kinase C / metabolism; Signal Transduction; Stem Cell Transplantation / methods; Ventricular Remodeling / physiology
Source: Crossref
Added: July 21, 2019

2014 journal article

Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy

Stem Cell Reports, 2(5), 606–619.

By: A. Ibrahim*, K. Cheng* & E. Marbán*

MeSH headings : Albumins / pharmacology; Aniline Compounds / pharmacology; Animals; Benzylidene Compounds / pharmacology; Cell Differentiation; Cell Proliferation; Cell- and Tissue-Based Therapy; Cells, Cultured; Disease Models, Animal; Exosomes / metabolism; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Knockout; Mice, SCID; MicroRNAs / genetics; MicroRNAs / metabolism; Myocardial Infarction / therapy; Myocardial Infarction / veterinary; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Neovascularization, Physiologic; Polyesters / pharmacology; Rats; Rats, Sprague-Dawley; Regeneration
Source: Crossref
Added: July 21, 2019

2014 journal article

Relative Roles of CD90 and c-Kit to the Regenerative Efficacy of Cardiosphere-Derived Cells in Humans and in a Mouse Model of Myocardial Infarction

JOURNAL OF THE AMERICAN HEART ASSOCIATION, 3(5).

By: K. Cheng n, A. Ibrahim, M. Hensley n, D. Shen*, B. Sun, R. Middleton, W. Liu, R. Smith*, E. Marban

author keywords: cardiosphere-derived cells; CD90; ckit; myocardial infarction
MeSH headings : Analysis of Variance; Animals; Apoptosis / physiology; Biomarkers / analysis; Cell Differentiation / physiology; Cell Transplantation / methods; Cells, Cultured; Disease Models, Animal; Heart Function Tests; Humans; Male; Mice; Mice, SCID; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / transplantation; Prospective Studies; Proto-Oncogene Proteins c-kit / metabolism; Regeneration / physiology; Role; Sensitivity and Specificity; Thy-1 Antigens / metabolism; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy

PLOS ONE, 9(12).

By: K. Yee, K. Malliaras, H. Kanazawa, E. Tseliou, K. Cheng n, D. Luthringer, C. Ho*, K. Takayama* ...

MeSH headings : Administration, Cutaneous; Animals; Cardiomyopathies / complications; Cardiomyopathies / immunology; Cardiomyopathies / pathology; Cardiomyopathies / therapy; Catheters; Cicatrix / complications; Cicatrix / pathology; Dilatation; Endocardium / pathology; Female; Injections; Magnetic Resonance Imaging; Male; Myocardial Ischemia / complications; Myocardial Ischemia / immunology; Myocardial Ischemia / pathology; Myocardial Ischemia / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Regeneration; Spheroids, Cellular / cytology; Spheroids, Cellular / transplantation; Survival Analysis; Sus scrofa; Transplantation, Homologous / adverse effects
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Stem Cells and Regenerative Medicine in Domestic and Companion Animals: A Multispecies Perspective

Reproduction in Domestic Animals, 49, 2–10.

By: N. Gonçalves, C. Ambrósio & J. Piedrahita n

MeSH headings : Adult; Animals; Animals, Domestic / embryology; Cats; Dogs; Embryonic Stem Cells; Horses; Humans; Induced Pluripotent Stem Cells; Mice; Pets / embryology; Rats; Regenerative Medicine / trends; Stem Cells
Sources: Web Of Science, Crossref
Added: August 6, 2018

2014 journal article

Magnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarction

BIOMATERIALS, 35(30), 8528–8539.

By: A. Vandergriff*, T. Hensley n, E. Henry*, D. Shen*, S. Anthony n, J. Zhang*, K. Cheng n

author keywords: Cardiac stem cells; Magnetic targeting; Myocardial infarction; Ferumoxytol; MRI; Superparamagnetic iron oxide nanoparticles
MeSH headings : Animals; Apoptosis / drug effects; Cell Movement / drug effects; Cell Proliferation / drug effects; Cell Survival / drug effects; Female; Ferrosoferric Oxide / pharmacology; Ferrosoferric Oxide / therapeutic use; Finite Element Analysis; Heart Function Tests; Heparin / pharmacology; Humans; Inflammation / pathology; Iron Overload / pathology; Magnetic Phenomena; Male; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Nanoparticles / therapeutic use; Nanoparticles / ultrastructure; Neovascularization, Physiologic / drug effects; Protamines / pharmacology; Rats; Rats, Inbred WKY; Spheroids, Cellular / drug effects; Spheroids, Cellular / pathology
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Magnetic antibody-linked nanomatchmakers for therapeutic cell targeting

Nature Communications, 5(1).

By: K. Cheng n, D. Shen*, M. Hensley n, R. Middleton, B. Sun, W. Liu, G. De Couto, E. Marbán

MeSH headings : Animals; Antibodies; Bone Marrow Cells / metabolism; Bone Marrow Transplantation / methods; Cell Movement; Ferrosoferric Oxide / therapeutic use; Iron; Leukocytes, Mononuclear / metabolism; Magnets; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Nanotechnology / methods; Rats; Regeneration; Stem Cells
Sources: Web Of Science, Crossref
Added: August 6, 2018

2014 review

From "ES-like" cells to induced pluripotent stem cells: A historical perspective in domestic animals

[Review of ]. THERIOGENOLOGY, 81(1), 103–111.

By: S. Koh n & J. Piedrahita n

author keywords: Pluripotent stem cells; Reprogramming; Large animals; Induced pluripotent stem cells
MeSH headings : Animals; Animals, Domestic / embryology; Animals, Domestic / physiology; Cattle; Dogs; Embryonic Stem Cells; Genomic Instability; Induced Pluripotent Stem Cells; Regenerative Medicine; Swine / physiology
Source: Web Of Science
Added: August 6, 2018