Translational Regenerative Medicine
NC State
Works Published in 2014
Displaying all 18 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
CD90/Thy-1-negative cardiosphere-derived cells exhibit augmented regenerative potency in humans and mice with myocardial infarction
Journal of the American Heart Association, 3(5), 001260.
Source: NC State University Libraries
Added: April 24, 2021
2014 journal article
Functional properties of bone marrow-derived MSC-based engineered cartilage are unstable with very long-term in vitro culture
Journal of Biomechanics, 47(9), 2173–2182.
author keywords: Mesenchymal stem cells; Chondrogenesis; Three-dimensional culture; Cartilage; Mechanical properties
MeSH headings : Animals; Bone Marrow Cells / cytology; Cartilage / cytology; Cartilage / metabolism; Cattle; Cell Survival; Cells, Cultured; Chondrocytes / cytology; Chondrogenesis; Femur; Glycosaminoglycans / metabolism; Hydrogels; Mesenchymal Stem Cells / cytology; Sepharose; Tissue Engineering / methods; Tissue Scaffolds
europepmc.org (repository)
Source: Crossref
Added: December 19, 2020
2014 journal article
Maximizing cartilage formation and integration via a trajectory-based tissue engineering approach
Biomaterials, 35(7), 2140–2148.
author keywords: Tissue engineering; Hyaluronic acid; Hydrogels; Cartilage; Integration; Maturation
MeSH headings : Animals; Cartilage / growth & development; Cattle; Tissue Engineering
Source: Crossref
Added: December 19, 2020
2014 journal article
Importance of Cell-Cell Contact in the Therapeutic Benefits of Cardiosphere-Derived Cells
STEM CELLS, 32(9), 2397–2406.
author keywords: Cardiosphere-derived cells; Cardiomyocyte; Proliferation; Paracrine factors; Cell-cell communication; beta 1 integrin
MeSH headings : Animals; Cell Communication / physiology; Cell Differentiation / physiology; Cells, Cultured; Humans; Integrin beta1 / metabolism; Male; Mice; Mice, SCID; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats
Source: Crossref
Added: August 28, 2020
2014 journal article
5 DISRUPTION OF THE HIGH MOBILITY GROUP AT-HOOK 2 (HMGA2) GENE IN SWINE REDUCES POSTNATAL GROWTH
Reproduction, Fertility and Development, 26(1), 117.
Source: Crossref
Added: February 24, 2020
2014 journal article
The Influence of MgO Nanoparticles on the Osseointegration of Polycaprolactone - Sodium Alginate Hydrogel Interfaces
British Journal of Applied Science & Technology, 4(1), 79–88.
Ed(s): M. Vimalan
Sources: Crossref, ORCID
Added: January 5, 2020
2014 journal article
Cardiosphere-derived Cells Stimulate Cardiomyocyte Proliferation via β1 Integrin Signaling
Stem Cells, 32, 2397–2406.
Source: NC State University Libraries
Added: July 28, 2019
2014 journal article
Intracoronary Cardiosphere-Derived Cells After Myocardial Infarction
Journal of the American College of Cardiology, 63(2), 110–122.
author keywords: cardiosphere-derived cells; myocardial infarction; myocardial regeneration
MeSH headings : Aged; Biopsy; Coronary Vessels; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Ventricles / pathology; Heart Ventricles / physiopathology; Humans; Injections, Intra-Arterial; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Infarction / complications; Myocardial Infarction / physiopathology; Myocardial Infarction / surgery; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Recovery of Function; Stem Cell Transplantation / methods; Time Factors; Transplantation, Autologous; Treatment Outcome; Ventricular Dysfunction, Left / etiology; Ventricular Dysfunction, Left / physiopathology; Ventricular Dysfunction, Left / surgery; Ventricular Function, Left / physiology
Source: Crossref
Added: July 21, 2019
2014 journal article
Human Cardiosphere-Derived Cells From Advanced Heart Failure Patients Exhibit Augmented Functional Potency in Myocardial Repair
JACC: Heart Failure, 2(1), 49–61.
author keywords: cardiosphere-derived cells; heart failure; myocardial infarction; patient characteristics; stromal cell-derived factor 1
MeSH headings : Adult; Aged; Animals; Cardiomyopathies / physiopathology; Extracellular Matrix; Female; Graft Survival / physiology; Heart / physiology; Heart Failure / physiopathology; Humans; Intercellular Signaling Peptides and Proteins / metabolism; Male; Mice, SCID; Middle Aged; Myocardial Infarction / physiopathology; Myocytes, Cardiac / physiology; Neovascularization, Physiologic / physiology; Oxidative Stress / physiology; Regeneration / physiology; Stem Cell Transplantation / methods; Stem Cells / physiology; Transplantation, Autologous
Source: Crossref
Added: July 21, 2019
2014 journal article
Engineered Electrical Conduction Tract Restores Conduction in Complete Heart Block
Journal of the American College of Cardiology, 64(24), 2575–2585.
author keywords: arrhythmias; cardiac tissue engineering; gap junctions; heart conduction system
MeSH headings : Animals; Atrioventricular Block / pathology; Atrioventricular Block / physiopathology; Atrioventricular Block / surgery; Cell Transplantation / methods; Cells, Cultured; Electromagnetic Fields; Heart Conduction System / pathology; Heart Conduction System / physiopathology; Heart Conduction System / surgery; Heart Ventricles / pathology; Immunoconjugates / pharmacology; In Vitro Techniques; Magnets; Models, Cardiovascular; Myocytes, Cardiac / pathology; Rats; Rats, Sprague-Dawley; Sarcoglycans / immunology; Sarcoglycans / pharmacology; Tissue Engineering
Source: Crossref
Added: July 21, 2019
2014 journal article
Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy
European Heart Journal, 36(12), 751–762.
author keywords: Cardiomyopathy; Heart failure; Cell transplantation
MeSH headings : Animals; Apoptosis / physiology; CREB-Binding Protein / metabolism; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / physiopathology; Cardiomyopathy, Dilated / therapy; Cell Differentiation; Cell Lineage; Disease Models, Animal; Doxorubicin / pharmacology; Fibrosis; Graft Survival; Heart Failure / pathology; Heart Failure / physiopathology; Heart Failure / therapy; Injections, Intralesional; Male; Mice, Transgenic; Myocarditis / physiopathology; Myocardium / pathology; Myocytes, Cardiac / transplantation; Oxidative Stress / physiology; Protein Kinase C / metabolism; Signal Transduction; Stem Cell Transplantation / methods; Ventricular Remodeling / physiology
Source: Crossref
Added: July 21, 2019
2014 journal article
Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy
Stem Cell Reports, 2(5), 606–619.
MeSH headings : Albumins / pharmacology; Aniline Compounds / pharmacology; Animals; Benzylidene Compounds / pharmacology; Cell Differentiation; Cell Proliferation; Cell- and Tissue-Based Therapy; Cells, Cultured; Disease Models, Animal; Exosomes / metabolism; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Knockout; Mice, SCID; MicroRNAs / genetics; MicroRNAs / metabolism; Myocardial Infarction / therapy; Myocardial Infarction / veterinary; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Neovascularization, Physiologic; Polyesters / pharmacology; Rats; Rats, Sprague-Dawley; Regeneration
Source: Crossref
Added: July 21, 2019
2014 journal article
Relative Roles of CD90 and c-Kit to the Regenerative Efficacy of Cardiosphere-Derived Cells in Humans and in a Mouse Model of Myocardial Infarction
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 3(5).
author keywords: cardiosphere-derived cells; CD90; ckit; myocardial infarction
MeSH headings : Analysis of Variance; Animals; Apoptosis / physiology; Biomarkers / analysis; Cell Differentiation / physiology; Cell Transplantation / methods; Cells, Cultured; Disease Models, Animal; Heart Function Tests; Humans; Male; Mice; Mice, SCID; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / transplantation; Prospective Studies; Proto-Oncogene Proteins c-kit / metabolism; Regeneration / physiology; Role; Sensitivity and Specificity; Thy-1 Antigens / metabolism; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy
PLOS ONE, 9(12).
MeSH headings : Administration, Cutaneous; Animals; Cardiomyopathies / complications; Cardiomyopathies / immunology; Cardiomyopathies / pathology; Cardiomyopathies / therapy; Catheters; Cicatrix / complications; Cicatrix / pathology; Dilatation; Endocardium / pathology; Female; Injections; Magnetic Resonance Imaging; Male; Myocardial Ischemia / complications; Myocardial Ischemia / immunology; Myocardial Ischemia / pathology; Myocardial Ischemia / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Regeneration; Spheroids, Cellular / cytology; Spheroids, Cellular / transplantation; Survival Analysis; Sus scrofa; Transplantation, Homologous / adverse effects
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Stem Cells and Regenerative Medicine in Domestic and Companion Animals: A Multispecies Perspective
Reproduction in Domestic Animals, 49, 2–10.
MeSH headings : Adult; Animals; Animals, Domestic / embryology; Cats; Dogs; Embryonic Stem Cells; Horses; Humans; Induced Pluripotent Stem Cells; Mice; Pets / embryology; Rats; Regenerative Medicine / trends; Stem Cells
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 journal article
Magnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarction
BIOMATERIALS, 35(30), 8528–8539.
author keywords: Cardiac stem cells; Magnetic targeting; Myocardial infarction; Ferumoxytol; MRI; Superparamagnetic iron oxide nanoparticles
MeSH headings : Animals; Apoptosis / drug effects; Cell Movement / drug effects; Cell Proliferation / drug effects; Cell Survival / drug effects; Female; Ferrosoferric Oxide / pharmacology; Ferrosoferric Oxide / therapeutic use; Finite Element Analysis; Heart Function Tests; Heparin / pharmacology; Humans; Inflammation / pathology; Iron Overload / pathology; Magnetic Phenomena; Male; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Nanoparticles / therapeutic use; Nanoparticles / ultrastructure; Neovascularization, Physiologic / drug effects; Protamines / pharmacology; Rats; Rats, Inbred WKY; Spheroids, Cellular / drug effects; Spheroids, Cellular / pathology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Magnetic antibody-linked nanomatchmakers for therapeutic cell targeting
Nature Communications, 5(1).
MeSH headings : Animals; Antibodies; Bone Marrow Cells / metabolism; Bone Marrow Transplantation / methods; Cell Movement; Ferrosoferric Oxide / therapeutic use; Iron; Leukocytes, Mononuclear / metabolism; Magnets; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Nanotechnology / methods; Rats; Regeneration; Stem Cells
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 review
From "ES-like" cells to induced pluripotent stem cells: A historical perspective in domestic animals
[Review of ]. THERIOGENOLOGY, 81(1), 103–111.
author keywords: Pluripotent stem cells; Reprogramming; Large animals; Induced pluripotent stem cells
MeSH headings : Animals; Animals, Domestic / embryology; Animals, Domestic / physiology; Cattle; Dogs; Embryonic Stem Cells; Genomic Instability; Induced Pluripotent Stem Cells; Regenerative Medicine; Swine / physiology
Source: Web Of Science
Added: August 6, 2018
