Works Published in 2011
Displaying works 121 - 140 of 225 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
AGRICOH: A Consortium of Agricultural Cohorts
International Journal of Environmental Research and Public Health, 8(5), 1341–1357.
Contributors: M. Leon*, L. Beane Freeman*, J. Douwes *, J. Hoppin* , H. Kromhout *, P. Lebailly*, K. Nordby*, M. Schenker *
author keywords: agriculture; cohort studies; consortium, pesticides; occupational exposures
MeSH headings : Agricultural Workers' Diseases; Agriculture; Cohort Studies; Humans; International Cooperation; Occupational Exposure
TL;DR:
Altogether, AGRICOH provides excellent opportunities for studying cancer, respiratory, neurologic, and auto-immune diseases as well as reproductive and allergic disorders, injuries and overall mortality in association with a wide array of exposures, prominent among these the application of pesticides.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
mGluR and NMDAR activation internalize distinct populations of AMPARs
Molecular and Cellular Neuroscience, 48(2), 161–170.
MeSH headings : Animals; Carrier Proteins / genetics; Carrier Proteins / metabolism; Cells, Cultured; Endocytosis / physiology; Hippocampus / cytology; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Long-Term Synaptic Depression / physiology; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Neurons / cytology; Neurons / physiology; Patch-Clamp Techniques; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; Rats; Rats, Sprague-Dawley; Receptors, AMPA / metabolism; Receptors, Metabotropic Glutamate / metabolism; Receptors, N-Methyl-D-Aspartate / metabolism; Signal Transduction / physiology
TL;DR:
Evidence is reported that these two receptor pathways couple to the endocytosis of distinct populations of AMPARs defined by their mobility in the membrane surface, which suggests that the convergence of the mGluR and NMDAR signaling pathways on AMPAR endocyTosis renders these two forms of plasticity functionally equivalent.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2011 journal article
The curation paradigm and application tool used for manual curation of the scientific literature at the Comparative Toxicogenomics Database
Database, 2011(0), bar034–bar034.
MeSH headings : Database Management Systems; Databases, Factual; Disease; Humans; Internet; Pharmaceutical Preparations; Toxicogenetics; User-Computer Interface; Vocabulary, Controlled
TL;DR:
This approach to manual curation that uses a powerful and efficient paradigm involving mnemonic codes is incorporated into a web-based curation tool to further increase efficiency and productivity, implement quality control in real-time and accommodate biocurators working remotely.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 7, 2019
2011 journal article
DiseaseComps: a metric that discovers similar diseases based upon common toxicogenomic profiles at CTD
Bioinformation, 7(4), 154–156.
TL;DR:
This work leveraged curated datasets to compute similarity indices that can be used to produce lists of comparable diseases (“DiseaseComps”) based upon shared toxicogenomic profiles, which now classifies diseases with common molecular characteristics, instead of the traditional approach of using histology or tissue of origin to define the disorder.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 7, 2019
2011 journal article
A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos
Development, 139(2), 437–442.
author keywords: Small-molecule inhibitor; Rho kinase; Photocaging; Xenopus
MeSH headings : Animals; Body Patterning / drug effects; Dioxoles / metabolism; Dioxoles / pharmacology; Embryo, Nonmammalian / metabolism; Immunohistochemistry; Indoles / metabolism; Indoles / pharmacology; Mice; NIH 3T3 Cells; Pyridines / metabolism; Pyridines / pharmacology; Ultraviolet Rays; Xenopus laevis / embryology; Xenopus laevis / metabolism; rho-Associated Kinases / antagonists & inhibitors; rho-Associated Kinases / metabolism
TL;DR:
A novel pharmacological agent that can be light activated to achieve spatiotemporally limited inhibition of Rho kinase activity in vivo is developed and application to the spatially heterogeneous problem of embryonic left-right asymmetry revealed a differential requirement for Rho signaling on the left and right sides of the primitive gut tube.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, Crossref
Added: May 17, 2019
2011 journal article
Toxicological studies on silver nanoparticles: challenges and opportunities in assessment, monitoring and imaging
Nanomedicine, 6(5), 879–898.
Contributors: M. Stensberg*, Q. Wei* , E. McLamore *, D. Porterfield *, A. Wei * & M. Sepulveda *
author keywords: cell uptake; characterization methods; imaging; physiological sensing; silver nanoparticles; toxicology
MeSH headings : Animals; Environmental Monitoring / methods; Humans; Microscopy / methods; Nanoparticles / analysis; Nanoparticles / toxicity; Silver / analysis; Silver / toxicity
TL;DR:
Several proposed mechanisms of cytotoxicity based on recent research on the transport, activity and fate of Ag NPs at the cellular and organismic level are discussed, in conjunction with traditional and recently established methods of nanoparticle characterization.
(via Semantic Scholar)
Source: ORCID
Added: March 21, 2019
2011 journal article
Optical Imaging with Dynamic Contrast Agents
Chemistry-a European Journal, 17(4), 1080–1091.
author keywords: contrast agents; imaging techniques; magnetic properties; nanoparticles; photothermal reactions
MeSH headings : Contrast Media / chemistry; Diagnostic Imaging; Fluorescence; Image Processing, Computer-Assisted; Magnetics; Molecular Dynamics Simulation; Nanoparticles / chemistry
TL;DR:
Dynamic contrast is an emerging topic with considerable room for development, both with respect to molecular or nanoscale probes for signal modulation, and also to methods for more efficient image processing and editing.
(via Semantic Scholar)
Source: ORCID
Added: March 21, 2019
2011 journal article
Metal-Mesh Lithography
Acs Applied Materials &Amp; Interfaces, 3(12), 4812–4818.
author keywords: lithography; surface chemistry; microarrays; chemisorption; wetting
MeSH headings : Copper / chemistry; Printing / instrumentation; Printing / methods; Surface Properties
TL;DR:
Metal-mesh lithography is a practical hybrid of microcontact printing and capillary force lithography that can be applied over millimeter-sized areas with a high level of uniformity, and can be reproduced with low micrometer resolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: March 21, 2019
2011 article
Gold Nanorods as Theranostic Agents
Wei, A., Wei, Q., & Leonov, A. P. (2011, May). Nanoplatform-Based Molecular Imaging, pp. 659–681.
Source: ORCID
Added: March 21, 2019
2011 journal article
Global distribution and climate forcing of marine organic aerosol: 1. Model improvements and evaluation
Atmospheric Chemistry and Physics, 11(22), 11689–11705.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Mucin granule-associated proteins in human bronchial epithelial cells: the airway goblet cell "granulome"
RESPIRATORY RESEARCH, 12.
MeSH headings : Bronchi / chemistry; Bronchi / metabolism; Cells, Cultured; Cytoplasmic Granules / chemistry; Cytoplasmic Granules / metabolism; Cytoplasmic Granules / ultrastructure; Goblet Cells / chemistry; Goblet Cells / metabolism; Humans; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / metabolism; Membrane Glycoproteins / ultrastructure; Mucins / chemistry; Mucins / metabolism; Respiratory Mucosa / chemistry; Respiratory Mucosa / metabolism
TL;DR:
This work isolated mucin granules and granule membranes from primary cultures of well differentiated human bronchial epithelial cells utilizing a novel technique of immuno-isolation, based on the presence of the calcium activated chloride channel hCLCA1 on thegranule membranes, and verified via Western blotting and co-immunoprecipitation that MARCKS, HSP70, CSP and hCL CA1 were present on the granule membrane and associated with each other.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Application of WRF/Chem-MADRID for real-time air quality forecasting over the Southeastern United States
ATMOSPHERIC ENVIRONMENT, 45(34), 6241–6250.
author keywords: O-3; PM2.5; WRF/Chem-MADRID; Online-coupled model; Discrete evaluation; Categorical evaluation
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 article
Guest Editors' Introduction to the Special Issue on "Computer Models and Spatial Statistics for Environmental Science"
Reich, B. J., & Haran, M. (2011, December). JOURNAL OF AGRICULTURAL BIOLOGICAL AND ENVIRONMENTAL STATISTICS, Vol. 16, pp. 451–452.
TL;DR:
Researchers tackle several important statistical problems that arise in the analysis of computer model output, for example calibrating model output with observed data, comparing and combing output from several computer models and physical observations, and building statistical emulators for computer models to predict the outcome of the models for new sets of input conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Food rationing affects dietary selenium bioaccumulation and life cycle performance in the mayfly Centroptilum triangulifer
ECOTOXICOLOGY, 20(8), 1840–1851.
author keywords: Selenium; Mayfly; Periphyton; Toxicity; Maternal transfer; Fecundity; Trophic transfer; Chronic; Bioconcentration
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Body Weight; Female; Fertility; Food Chain; Insecta / growth & development; Insecta / metabolism; Insecta / physiology; Life Cycle Stages; Ovum; Selenium / pharmacokinetics
TL;DR:
The results suggest that the influence of Se on mayfly performance in nature may be tied to food resource availability and quality and nutritional status is an important consideration when applying laboratory derived estimates of toxicity to risk assessments for wild populations.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Membrane protein complexes catalyze both 4-and 3-hydroxylation of cinnamic acid derivatives in monolignol biosynthesis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(52), 21253–21258.
MeSH headings : Carboxylic Ester Hydrolases / chemistry; Carboxylic Ester Hydrolases / metabolism; Chromatography, Liquid; Coumaric Acids; DNA Primers / genetics; Hydroxylation; Immunoprecipitation; Kinetics; Lignin / biosynthesis; Mass Spectrometry; Membrane Proteins / chemistry; Membrane Proteins / metabolism; Microscopy, Confocal; Molecular Structure; Multiprotein Complexes / chemistry; Multiprotein Complexes / metabolism; Phenols; Phenylpropionates; Plasmids / genetics; Populus / metabolism; Propionates; Trans-Cinnamate 4-Monooxygenase / chemistry; Trans-Cinnamate 4-Monooxygenase / metabolism; Xylem / metabolism; Yeasts
TL;DR:
Affinity purification-quantitative mass spectrometry, bimolecular fluorescence complementation, chemical cross-linking, and reciprocal coimmunoprecipitation provide further evidence for functional involvement of membrane protein complexes in monolignol biosynthesis.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Inhibition of autophagy by TAB2 and TAB3
EMBO JOURNAL, 30(24), 4908–4920.
author keywords: Beclin 1 interactome; mTOR; p53; pifithrin alpha; rapamycin; stress response
TL;DR:
The results point to the existence of an autophagy‐stimulatory ‘switch’ whereby TAB2 and TAB3 abandon inhibitory interactions with Beclin 1 to engage in a stimulatory liaison with TAK1.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Global optimization of the infrared matrix-assisted laser desorption electrospray ionization (IR MALDESI) source for mass spectrometry using statistical design of experiments
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 25(23), 3527–3536.
MeSH headings : Animals; Cattle; Cytochromes c / analysis; Cytochromes c / chemistry; Horses; Limit of Detection; Research Design; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR:
The use of statistical DOE is described to improve a few of the analytical figures of merit of the infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) source for mass spectrometry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Effects of Instrumental Insemination and Insemination Quantity on Dufour’s Gland Chemical Profiles and Vitellogenin Expression in Honey Bee Queens (Apis mellifera)
Journal of Chemical Ecology, 37(9), 1027–1036.
author keywords: Chemical ecology; Gene expression; Behavior; Social insects; Pheromone
MeSH headings : Animals; Bees / genetics; Bees / metabolism; Bees / physiology; Female; Gene Expression Regulation; Insemination; Male; Pheromones / metabolism; Vitellogenins / genetics
TL;DR:
It appears that the differences in behavioral responses were elicited by subtle changes in the overall chemical profiles rather than dramatic changes in specific individual chemicals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung
ACS NANO, 5(12), 9772–9787.
author keywords: multiwalled carbon nanotubes (MWCNTs); dispersion; TGF-beta 1; PDGF-AA; IL-1 beta; collagen; lung fibrosis
MeSH headings : Animals; Biomarkers / metabolism; Cytokines / metabolism; Dose-Response Relationship, Drug; Lung / drug effects; Lung / metabolism; Mice; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Tissue Distribution
TL;DR:
The results indicate that the dispersal state of MWCNTs affects profibrogenic cellular responses that correlate with the extent of pulmonary fibrosis and are of potential use to predict pulmonary toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Consecutive Virgin Births in the New World Boid Snake, the Colombian Rainbow Boa, Epicrates maurus
Journal of Heredity, 102(6), 759–763.
author keywords: asexual reproduction; Boidae; facultative parthenogenesis; microsatellite DNA fingerprinting; Serpentes
MeSH headings : Animals; Boidae / genetics; DNA Fingerprinting; Female; Heterozygote; Homozygote; Microsatellite Repeats; Parthenogenesis / genetics; Parturition / genetics; Reproduction / genetics; Sex Determination Analysis; Sex Determination Processes / genetics
TL;DR:
This study provides genetic evidence for consecutive virgin births by a female Colombian rainbow boa (Epicrates maurus), resulting in the production of WW females likely through terminal fusion automixis, the first record of parthenogenesis within the genus Epicrates, a second within the serpent lineage Boidae, and the third genetically confirmed case of consecutiveirgin births of viable offspring within any vertebrate lineage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
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