Works (61)

Updated: January 8th, 2024 11:25

2023 article

House dust mite extract forms a der p 2 corona on multi-walled carbon nanotubes: implications for allergic airway disease

Dominguez, J., Holmes, S. K., Bartone, R. D., Tisch, L. J., Tighe, R. M., Bonner, J. C., & Payne, C. K. (2023, December 15). ENVIRONMENTAL SCIENCE-NANO.

By: J. Dominguez, S. Holmes, R. Bartone, L. Tisch, R. Tighe, J. Bonner, C. Payne

Source: Web Of Science
Added: January 2, 2024

2023 journal article

Role of the protease-activated receptor-2 (PAR2) in the exacerbation of house dust mite-induced murine allergic lung disease by multi-walled carbon nanotubes

PARTICLE AND FIBRE TOXICOLOGY, 20(1).

By: H. Lee n, D. You n, A. Taylor-Just n, L. Tisch n, R. Bartone n, H. Atkins n, L. Ralph*, S. Antoniak*, J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Carbon nanotubes; Allergens; Protease-activated receptor 2; Lung; Inflammation; Fibrosis
Source: Web Of Science
Added: August 28, 2023

2022 article

Pulmonary exposure of mice to ammonium perfluoro(2-methyl-3-oxahexanoate) (GenX) suppresses the innate immune response to carbon black nanoparticles and stimulates lung cell proliferation

Lee, H. Y., You, D. J., Taylor-Just, A. J., Linder, K. E., Atkins, H. M., Ralph, L. M., … Bonner, J. C. (2022, June 14). INHALATION TOXICOLOGY.

By: H. Lee n, D. You n, A. Taylor-Just n, K. Linder n, H. Atkins n, L. Ralph*, G. Cruz*, J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Carbon black; nanoparticles; PFAS; lung; immunity
MeSH headings : Ammonium Compounds / toxicity; Animals; Bronchoalveolar Lavage Fluid / chemistry; Cell Proliferation; Cytokines / metabolism; Fluorocarbons / toxicity; Immunity, Innate; Ki-67 Antigen / metabolism; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B / metabolism; Nanoparticles / toxicity; Soot / toxicity
Source: Web Of Science
Added: June 27, 2022

2022 journal article

Synergistic induction of IL-6 production in human bronchial epithelial cells in vitro by nickel nanoparticles and lipopolysaccharide is mediated by eSTAT3 and C/EBP beta

TOXICOLOGY IN VITRO, 83.

By: D. You n, H. Lee n, A. Taylor-Just n & J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Nanoparticles; Nickel; Lipopolysaccharide; Cytokines; Cell signaling; Epithelial cells
MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-beta / metabolism; Cell Line; Epithelial Cells; Female; Humans; Interleukin-6 / genetics; Interleukin-6 / metabolism; Lipopolysaccharides / pharmacology; Male; Mice; Nanoparticles; Nickel; STAT3 Transcription Factor / metabolism
Source: Web Of Science
Added: August 15, 2022

2021 journal article

Femtosecond pulsed laser microscopy: a new tool to assess the in vitro delivered dose of carbon nanotubes in cell culture experiments

PARTICLE AND FIBRE TOXICOLOGY, 18(1).

By: D. Lison*, S. Ibouraadaten*, S. Brule*, M. Todea*, A. Vulpoi*, F. Turcu*, C. Ziemann*, O. Creutzenberg* ...

co-author countries: Belgium 🇧🇪 Germany 🇩🇪 Romania 🇷🇴 United States of America 🇺🇸
author keywords: Particokinetics; Turbidity assay
MeSH headings : Cell Culture Techniques; Macrophages; Microscopy, Confocal; Monocytes; Nanotubes, Carbon
Source: Web Of Science
Added: March 8, 2021

2021 journal article

Osteopontin mRNA expression by rat mesothelial cells exposed to multi-walled carbon nanotubes as a potential biomarker of chronic neoplastic transformation in vitro

TOXICOLOGY IN VITRO, 73.

By: S. Sridharan n, A. Taylor-Just n & J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Carbon nanotubes; Osteopontin; Mesothelial cells; Mesothelioma
MeSH headings : Animals; Biomarkers; Cell Line; Cell Transformation, Neoplastic / genetics; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Male; Mesothelioma / genetics; Nanotubes, Carbon / toxicity; Osteopontin / genetics; Pleura / cytology; RNA, Messenger; Rats, Inbred F344
Source: Web Of Science
Added: June 10, 2021

2021 journal article

STAT6-dependent exacerbation of house dust mite-induced allergic airway disease in mice by multi-walled carbon nanotubes

NANOIMPACT, 22.

By: M. Ihrie n, K. Duke n, K. Shipkowski n, D. You n, H. Lee n, A. Taylor-Just n, J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Carbon nanotubes; House dust mite; Allergens; STAT6; Asthma
MeSH headings : Animals; Antigens, Dermatophagoides / adverse effects; Asthma / chemically induced; Dermatophagoides pteronyssinus; Fibrosis; Hypersensitivity / metabolism; Immunoglobulin E; Lung; Male; Metaplasia / chemically induced; Mice; Mice, Knockout; Nanotubes, Carbon / adverse effects; Pulmonary Eosinophilia / chemically induced; Pulmonary Fibrosis / chemically induced; Respiration Disorders / chemically induced; STAT6 Transcription Factor / genetics
Source: Web Of Science
Added: June 21, 2021

2021 journal article

Sex Differences in Pulmonary Eicosanoids and Specialized Pro-Resolving Mediators in Response to Ozone Exposure

TOXICOLOGICAL SCIENCES, 183(1), 170–183.

By: M. Yaeger*, S. Reece*, B. Kilburg-Basnyat*, M. Hodge*, A. Pal*, K. Dunigan-Russell*, B. Luo*, D. You n ...

co-author countries: United States of America 🇺🇸
author keywords: air pollution; lipids; lung; inflammation; sex differences
MeSH headings : Animals; Eicosanoids; Female; Lung; Male; Mice; Mice, Inbred C57BL; Ozone / toxicity; Sex Characteristics
Source: Web Of Science
Added: September 27, 2021

2020 book

Interaction of Nanomaterials with the Immune System

James Bonner

Ed(s): J. Bonner & J. Brown

Source: Crossref
Added: February 5, 2022

2020 article

Interaction of Nanomaterials with the Immune System Introduction

INTERACTION OF NANOMATERIALS WITH THE IMMUNE SYSTEM, pp. 1–14.

By: J. Bonner n & J. Brown*

co-author countries: United States of America 🇺🇸
author keywords: Nanotechnology; Immune system; Immunotoxicity
Source: Web Of Science
Added: August 16, 2021

2020 article

Macrophages: First Innate Immune Responders to Nanomaterials

INTERACTION OF NANOMATERIALS WITH THE IMMUNE SYSTEM, pp. 15–34.

By: D. You n, H. Lee n & J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Macrophage; Nanomaterial; Toll-like receptors; Scavenger receptors; Reactive oxygen species; Inflammasome; Polarization
Source: Web Of Science
Added: August 16, 2021

2020 journal article

Sex differences in the acute and subchronic lung inflammatory responses of mice to nickel nanoparticles

NANOTOXICOLOGY, 14(8), 1058–1081.

By: D. You n, H. Lee n, A. Taylor-Just n, K. Linder n & J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Nickel nanoparticles; inflammation; lung; sex; susceptibility
MeSH headings : Animals; Bronchoalveolar Lavage Fluid / cytology; Chemokine CXCL1 / metabolism; Female; Humans; Inhalation Exposure; Interleukin-6 / metabolism; Lung / drug effects; Lung / immunology; Lung / pathology; Male; Metal Nanoparticles / toxicity; Mice; Mice, Inbred C57BL; Neutrophils / cytology; Neutrophils / drug effects; Nickel / toxicity; Pneumonia / chemically induced; Pneumonia / pathology; STAT Transcription Factors / metabolism; Sex Characteristics; Signal Transduction; Toxicity Tests, Acute; Toxicity Tests, Subchronic
Source: Web Of Science
Added: September 7, 2020

2020 review

Susceptibility Factors in Chronic Lung Inflammatory Responses to Engineered Nanomaterials

[Review of ]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(19).

By: D. You n & J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: engineered nanomaterials; susceptibility; chronic inflammation; lung inflammation
MeSH headings : Animals; Humans; Inflammation / chemically induced; Inflammation / complications; Inflammation / pathology; Inhalation Exposure; Lung / drug effects; Lung / pathology; Nanostructures / adverse effects; Nanostructures / therapeutic use; Pneumonia / complications; Pneumonia / drug therapy; Pneumonia / pathology
Source: Web Of Science
Added: November 24, 2020

2020 journal article

The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method

PARTICLE AND FIBRE TOXICOLOGY, 17(1).

By: A. Taylor-Just n, M. Ihrie n, K. Duke n, H. Lee n, D. You n, S. Hussain*, V. Kodali*, C. Ziemann* ...

co-author countries: Belgium 🇧🇪 Germany 🇩🇪 Romania 🇷🇴 United States of America 🇺🇸
author keywords: Carbon nanotubes; Purification; Functionalization; Lung injury; Fibrosis
MeSH headings : Administration, Inhalation; Air Pollutants / toxicity; Animals; Bronchoalveolar Lavage Fluid / chemistry; Cytokines / metabolism; Inhalation Exposure; Lung / drug effects; Lung Injury; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / toxicity; Transforming Growth Factor beta1 / metabolism
Source: Web Of Science
Added: December 21, 2020

2019 journal article

Inhalation exposure to multi-walled carbon nanotubes alters the pulmonary allergic response of mice to house dust mite allergen

INHALATION TOXICOLOGY, 31(5), 192–202.

By: M. Ihrie n, A. Taylor-Just n, N. Walker*, M. Stout*, A. Gupta*, J. Richey*, B. Hayden*, G. Baker* ...

co-author countries: United States of America 🇺🇸
author keywords: Carbon nanotubes; house dust mite allergen; asthma; inhalation; atopy; nanoparticles
MeSH headings : Animals; Antigens, Dermatophagoides / immunology; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Immunologic; Fibrosis; Hypersensitivity / physiopathology; Immunoglobulin E / blood; Inhalation Exposure / adverse effects; Interleukin-13 / analysis; Lung / physiology; Male; Mice; Nanotubes, Carbon / toxicity; Th2 Cells / immunology
Source: Web Of Science
Added: August 19, 2019

2018 article

ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNTs - Comparative in vitro investigations

Ziemann, C., Reamon-Buettner, S. M., Lison, D., Bonner, J. C., Brule, S., Simon, S., & Creutzenberg, O. H. (2018, October 10). TOXICOLOGY LETTERS, Vol. 295, pp. S213–S213.

By: C. Ziemann*, S. Reamon-Buettner*, D. Lison*, J. Bonner n, S. Brule*, S. Simon*, O. Creutzenberg*

co-author countries: Belgium 🇧🇪 Germany 🇩🇪 Romania 🇷🇴 United States of America 🇺🇸
Source: Web Of Science
Added: January 7, 2019

2018 review

Mechanisms of carbon nanotube-induced pulmonary fibrosis: A physicochemical characteristic perspective

[Review of ]. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, 10(3).

By: K. Duke & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes

NANOTOXICOLOGY, 12(9), 975–991.

By: K. Duke n, E. Thompson n, M. Ihrie n, A. Taylor-Just n, E. Ash n, K. Shipkowski n, J. Hall n, D. Tokarz n ...

co-author countries: United States of America 🇺🇸
author keywords: Caron nanotubes; immunotoxicology; cancer; granuloma; p53
MeSH headings : Animals; Dose-Response Relationship, Drug; Granuloma, Respiratory Tract / chemically induced; Granuloma, Respiratory Tract / genetics; Granuloma, Respiratory Tract / immunology; Inhalation Exposure; Lung / drug effects; Lung / immunology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Surface Properties; Tertiary Lymphoid Structures / chemically induced; Tertiary Lymphoid Structures / genetics; Tertiary Lymphoid Structures / immunology; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / physiology
Source: Web Of Science
Added: March 4, 2019

2018 journal article

Signal transducer and activator of transcription 1 regulates multiwalled carbon nanotube-induced pulmonary fibrosis in mice via suppression of transforming growth factor-beta 1 production and signaling

Annals of the American Thoracic Society, 15, S129–130.

By: K. Duke, A. Taylor, M. Ihrie, K. Shipkowski, E. Needham & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

The Toxicology of Engineered Nanomaterials in Asthma

Current Environmental Health Reports, 5(1), 100–109.

By: M. Ihrie n & J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Asthma; Allergy; Lung; Nanoparticles; Nanotubes; Nanomaterials
MeSH headings : Asthma / chemically induced; Humans; Lung / drug effects; Metal Nanoparticles / toxicity; Nanostructures / toxicity; Nanotubes, Carbon / toxicity
Source: Crossref
Added: February 24, 2020

2017 journal article

Mapping differential cellular protein response of mouse alveolar epithelial cells to multi-walled carbon nanotubes as a function of atomic layer deposition coating

NANOTOXICOLOGY, 11(3), 313–326.

By: G. Hilton n, A. Taylor n, S. Hussain*, E. Dandley n, E. Griffith n, S. Garantziotis*, G. Parsons n, J. Bonner n, M. Bereman n

co-author countries: United States of America 🇺🇸
author keywords: Carbon nanotube; label-free proteomics; pulmonary fibrosis; toxicoproteomics
MeSH headings : Aluminum Oxide / toxicity; Alveolar Epithelial Cells / chemistry; Alveolar Epithelial Cells / drug effects; Animals; Cells, Cultured; Mice; Nanotubes, Carbon / toxicity; Proteomics / methods; Pulmonary Fibrosis / etiology; Zinc Oxide / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Mechanisms of carbon nanotube-induced pulmonary fibrosis: a physicochemical characteristic perspective

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 10(3), e1498.

By: K. Duke n & J. Bonner n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cells, Cultured; Chemical Phenomena; Disease Models, Animal; Environmental Exposure; Epithelial-Mesenchymal Transition; Mice; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Nanotubes, Carbon / ultrastructure; Oxidative Stress; Pulmonary Fibrosis / chemically induced; Rats
Source: Crossref
Added: June 6, 2020

2017 journal article

STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes

PARTICLE AND FIBRE TOXICOLOGY, 14.

By: K. Duke n, A. Taylor-Just n, M. Ihrie n, K. Shipkowski n, E. Thompson n, E. Dandley n, G. Parsons n, J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: Carbon nanotubes; Lung; Fibrosis; Growth factors; Transcription factors
MeSH headings : Animals; Bronchoalveolar Lavage Fluid / chemistry; Cell Proliferation / drug effects; Cytokines / metabolism; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Epithelial Cells / pathology; Genetic Predisposition to Disease; Granuloma, Respiratory Tract / chemically induced; Granuloma, Respiratory Tract / metabolism; Granuloma, Respiratory Tract / pathology; Immunoglobulin E / blood; Lung / drug effects; Lung / metabolism; Lung / pathology; Male; Mice, Knockout; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Phenotype; Phosphorylation; Pneumonia / chemically induced; Pneumonia / metabolism; Pneumonia / pathology; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / genetics; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Respiratory Hypersensitivity / chemically induced; Respiratory Hypersensitivity / genetics; Respiratory Hypersensitivity / metabolism; Respiratory Hypersensitivity / pathology; Risk Assessment; STAT1 Transcription Factor / deficiency; STAT1 Transcription Factor / genetics; STAT1 Transcription Factor / metabolism; Signal Transduction / drug effects; Smad2 Protein / metabolism; Smad3 Protein / metabolism; Time Factors; Transforming Growth Factor beta1 / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Atomic layer deposition coating of carbon nanotubes with zinc oxide causes acute phase immune responses in human monocytes in vitro and in mice after pulmonary exposure

PARTICLE AND FIBRE TOXICOLOGY, 13.

By: E. Dandley n, A. Taylor n, K. Duke n, M. Ihrie n, K. Shipkowski n, G. Parsons n, J. Bonner n

co-author countries: United States of America 🇺🇸

Contributors: E. Dandley n, A. Taylor n, K. Duke n, M. Ihrie n, K. Shipkowski n, G. Parsons n, J. Bonner n

author keywords: Atomic layer deposition; Carbon nanotubes; Pulmonary fibrosis; Inflammation
MeSH headings : Acute-Phase Reaction / chemically induced; Acute-Phase Reaction / immunology; Acute-Phase Reaction / metabolism; Acute-Phase Reaction / pathology; Air Pollutants / chemistry; Air Pollutants / toxicity; Animals; Cell Line; Cytokines / agonists; Cytokines / genetics; Cytokines / metabolism; Disease Progression; Gene Expression Regulation / drug effects; Humans; Inhalation Exposure / adverse effects; Lung / drug effects; Lung / immunology; Lung / metabolism; Lung / pathology; Male; Mice, Inbred C57BL; Microscopy, Electron, Scanning Transmission; Monocytes / drug effects; Monocytes / immunology; Monocytes / metabolism; Monocytes / pathology; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Nanotubes, Carbon / ultrastructure; Pulmonary Fibrosis / etiology; RNA, Messenger / metabolism; Respiratory Mucosa / drug effects; Respiratory Mucosa / immunology; Respiratory Mucosa / pathology; Surface Properties; Zinc Oxide / chemistry; Zinc Oxide / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials

ARCHIVES OF TOXICOLOGY, 90(7), 1769–1783.

By: A. Clippinger, A. Ahluwalia*, D. Allen*, J. Bonner n, W. Casey, V. Castranova*, R. David*, S. Halappanavar* ...

co-author countries: Canada 🇨🇦 Switzerland 🇨🇭 Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Inhalation toxicity; Multi-walled carbon nanotubes; MWCNTs; In vitro testing strategies; Regulatory risk assessment; Pulmonary fibrosis
MeSH headings : Aerosols; Animal Use Alternatives; Animals; Cell Culture Techniques; Cells, Cultured; Equipment Design; Humans; Inhalation Exposure / adverse effects; Lung / cytology; Lung / drug effects; Models, Biological; Nanostructures / administration & dosage; Nanostructures / toxicity; Pulmonary Fibrosis / chemically induced; Toxicity Tests / instrumentation; Toxicity Tests / methods
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Multiwalled Carbon Nanotube Functionalization with High Molecular Weight Hyaluronan Significantly Reduces Pulmonary Injury

ACS NANO, 10(8), 7675–7688.

By: S. Hussain*, Z. Ji*, A. Taylor n, L. DeGraff, M. George*, C. Tucker, C. Chang*, R. Li*, J. Bonner n, S. Garantziotis*

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: multiwalled carbon nanotubes; hyaluronan; lung; inflammation; fibrosis; mucous metaplasia; differentiated human bronchial epithelia
MeSH headings : Fibroblasts; Humans; Hyaluronic Acid; Lung; Lung Injury / prevention & control; Macrophages, Alveolar; Molecular Weight; Nanotubes, Carbon
Source: Web Of Science
Added: August 6, 2018

2015 journal article

An allergic lung microenvironment suppresses carbon nanotube-induced inflammasome activation via STAT6-dependent inhibition of caspase-1

PLoS One, 10(6).

By: K. Shipkowski, A. Taylor, E. Thompson, E. Glista-Baker, B. Sayers, Z. Messenger, R. Bauer, I. Jaspers, J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Role of Signal Transducer and Activator of Transcription 1 in Murine Allergen-Induced Airway Remodeling and Exacerbation by Carbon Nanotubes

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 53(5), 625–636.

By: E. Thompson n, B. Sayers n, E. Glista-Baker n, K. Shipkowski n, M. Ihrie n, K. Duke n, A. Taylor n, J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: asthma; allergen; nanomaterials; carbon nanotubes; airway remodeling
MeSH headings : Allergens / pharmacology; Animals; Bronchoalveolar Lavage Fluid / chemistry; Eosinophils / drug effects; Eosinophils / immunology; Eosinophils / pathology; Epithelial Cells / drug effects; Epithelial Cells / immunology; Epithelial Cells / pathology; Gene Expression Regulation; Goblet Cells / drug effects; Goblet Cells / immunology; Goblet Cells / pathology; Interleukin-10 / genetics; Interleukin-10 / immunology; Interleukin-13 / genetics; Interleukin-13 / immunology; Male; Mice; Mice, Knockout; Nanotubes / adverse effects; Neutrophils / drug effects; Neutrophils / immunology; Neutrophils / pathology; Osteopontin / genetics; Osteopontin / immunology; Ovalbumin / immunology; Respiratory Hypersensitivity / etiology; Respiratory Hypersensitivity / genetics; Respiratory Hypersensitivity / immunology; Respiratory Hypersensitivity / pathology; STAT1 Transcription Factor / deficiency; STAT1 Transcription Factor / genetics; STAT1 Transcription Factor / immunology; Signal Transduction; T-Lymphocytes, Helper-Inducer / drug effects; T-Lymphocytes, Helper-Inducer / immunology; T-Lymphocytes, Helper-Inducer / pathology; Transforming Growth Factor beta1 / genetics; Transforming Growth Factor beta1 / immunology; Transforming Growth Factor beta1 / pharmacology; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / immunology
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Toxicoproteomic analysis of pulmonary carbon nanotube exposure using LC-MS/MS

TOXICOLOGY, 329, 80–87.

By: G. Hilton n, A. Taylor n, C. McClure n, G. Parsons n, J. Bonner n & M. Bereman n

co-author countries: United States of America 🇺🇸

Contributors: G. Hilton n, A. Taylor n, C. McClure n, G. Parsons n, J. Bonner n & M. Bereman n

author keywords: Carbon nanotube; Label-free proteomics; Pulmonary fibrosis; Toxicoproteomics
MeSH headings : Acute-Phase Proteins / genetics; Acute-Phase Proteins / metabolism; Animals; Bronchoalveolar Lavage Fluid / chemistry; Chromatography, Liquid; Complement C3 / genetics; Complement C3 / metabolism; Complement C4b / genetics; Complement C4b / metabolism; Complement C9 / genetics; Complement C9 / metabolism; Histones / genetics; Histones / metabolism; Lactoferrin / genetics; Lactoferrin / metabolism; Lipocalin-2; Lipocalins / genetics; Lipocalins / metabolism; Lung / drug effects; Lung / metabolism; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Oncogene Proteins / genetics; Oncogene Proteins / metabolism; Peroxidase / genetics; Peroxidase / metabolism; Proteome / metabolism; Pulmonary Surfactant-Associated Protein B / genetics; Pulmonary Surfactant-Associated Protein B / metabolism; Tandem Mass Spectrometry; Toxicity Tests
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo

PLOS ONE, 9(9).

By: A. Taylor n, C. McClure n, K. Shipkowski n, E. Thompson n, S. Hussain*, S. Garantziotis*, G. Parsons n, J. Bonner n

co-author countries: United States of America 🇺🇸

Contributors: A. Taylor n, C. McClure n, K. Shipkowski n, E. Thompson n, S. Hussain*, S. Garantziotis*, G. Parsons n, J. Bonner n

MeSH headings : Aluminum Oxide / pharmacology; Animals; Cell Death / drug effects; Cell Line; Cytokines / metabolism; Humans; Inflammation / pathology; Interleukin-1beta / biosynthesis; Interleukin-6 / metabolism; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / metabolism; Lung / drug effects; Lung / metabolism; Lung / pathology; Macrophages / drug effects; Macrophages / metabolism; Macrophages / ultrastructure; Mice, Inbred C57BL; Nanotechnology / methods; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / ultrastructure; Osteopontin / metabolism; Phagocytes / drug effects; Phagocytes / metabolism; Pulmonary Fibrosis; Soot / pharmacology; Surface Properties; Tumor Necrosis Factor-alpha / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Genetic susceptibility to interstitial pulmonary fibrosis in mice induced by vanadium pentoxide (V2O5)

FASEB JOURNAL, 28(3), 1098–1112.

By: D. Walters, K. White, U. Patel, M. Davis, R. Veluci-Marlow, S. Sunkesula, J. Bonner*, J. Martin*, W. Gladwell*, S. Kleeberger*

co-author countries: United States of America 🇺🇸
author keywords: lung injury; inflammation; collagen; haplotype; mapping
MeSH headings : Animals; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / genetics; Real-Time Polymerase Chain Reaction; Transforming Growth Factor beta / metabolism; Vanadium Compounds / toxicity
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts

Particle and Fibre Toxicology, 11.

By: S. Hussain, S. Sangtian, S. Anderson, R. Snyder, J. Marshburn, A. Rice, J. Bonner, S. Garantziotis

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Nickel Nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet)

Particle and Fibre Toxicology, 11.

By: E. Glista-Baker, A. Taylor, B. Sayers, E. Thompson & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Regulation and activity of secretory leukoprotease inhibitor (SLPI) is altered in smokers

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 306(3), L269–L276.

By: M. Meyer*, R. Bauer*, B. Letang*, L. Brighton*, E. Thompson n, R. Simmen*, J. Bonner n, I. Jaspers*

co-author countries: United States of America 🇺🇸
author keywords: cigarette smoking; epithelial cells; antiprotease
MeSH headings : Adult; Animals; Epithelial Cells / metabolism; Female; Humans; Leukocyte Elastase / antagonists & inhibitors; Lung / metabolism; Male; Mice; Nasal Lavage Fluid; Nasal Mucosa / metabolism; STAT1 Transcription Factor / biosynthesis; Secretory Leukocyte Peptidase Inhibitor / biosynthesis; Smoking / genetics
Source: Web Of Science
Added: August 6, 2018

2013 journal article

A Multi-Stakeholder Perspective on the Use of Alternative Test Strategies for Nanomaterial Safety Assessment

ACS Nano, 7(8), 6422–6433.

By: A. Nel*, E. Nasser*, H. Godwin*, D. Avery*, T. Bahadori*, L. Bergeson, E. Beryt*, J. Bonner n ...

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Animals; Congresses as Topic; Humans; International Cooperation; Materials Testing; Mice; Nanostructures / chemistry; Nanotechnology / methods; Nanotubes, Carbon / chemistry; Risk Assessment / methods; Safety; Toxicity Tests
Source: Crossref
Added: August 28, 2020

2013 journal article

A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment

ACS Nano, 7(8), 6422–6433.

By: A. Nel, E. Nasser, H. Godwin, D. Avery, T. Bahadori, L. Bergeson, E. Beryt, J. Bonner ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered n nanomaterials: The NIEHS Nano GO Consortium

Environmental Health Perspectives, 121(6), 683–690.

James Bonner; Alexia Just

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: The NIEHS Nano GO Consortium

Environmental Health Perspectives, 121(6), 676–682.

James Bonner; Alexia Just

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Nanomaterials as a potential cause of lung disease

Toxicology Letters, 221, S5.

By: J. Bonner n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: August 14, 2021

2013 journal article

Role of Cyclooxygenase-2 in Exacerbation of Allergen-Induced Airway Remodeling by Multiwalled Carbon Nanotubes

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 49(4), 525–535.

By: B. Sayers n, A. Taylor n, E. Glista-Baker n, J. Shipley-Phillips, R. Dackor, M. Edin, F. Lih, K. Tomer ...

co-author countries: United States of America 🇺🇸
author keywords: carbon nanotubes; nanoparticles; asthma; inflammation; COX-2
MeSH headings : Airway Remodeling / genetics; Airway Remodeling / immunology; Airway Remodeling / physiology; Allergens / immunology; Animals; Cyclooxygenase 1 / genetics; Cyclooxygenase 1 / immunology; Cyclooxygenase 1 / metabolism; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / immunology; Cyclooxygenase 2 / metabolism; Cytokines / immunology; Female; Inflammation / chemically induced; Inflammation / genetics; Inflammation / immunology; Inflammation / metabolism; Male; Membrane Proteins / genetics; Membrane Proteins / immunology; Membrane Proteins / metabolism; Metaplasia / genetics; Metaplasia / immunology; Metaplasia / metabolism; Mice; Mice, Inbred C57BL; Mucus / immunology; Mucus / metabolism; Nanotubes, Carbon; Ovalbumin / immunology; T-Lymphocytes, Helper-Inducer / immunology; T-Lymphocytes, Helper-Inducer / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP Kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages

Particle and Fibre Toxicology, 9.

By: J. Lee, B. Sayers, K. Chun, H. Lao, J. Shipley-Phillips, J. Bonner, R. Langenbach

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Nickel Nanoparticles Enhance Platelet-Derived Growth Factor-Induced Chemokine Expression by Mesothelial Cells via Prolonged Mitogen-Activated Protein Kinase Activation

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 47(4), 552–561.

By: E. Glista-Baker n, A. Taylor n, B. Sayers n, E. Thompson n & J. Bonner n

co-author countries: United States of America 🇺🇸
author keywords: nanoparticles; metals; lung; pleura; chemokines
MeSH headings : Acetylcysteine / pharmacology; Analysis of Variance; Animals; Antioxidants / pharmacology; Cell Line; Chemokine CCL2 / genetics; Chemokine CCL2 / metabolism; Chemokine CXCL10 / genetics; Chemokine CXCL10 / metabolism; Enzyme Activation; Epithelial Cells / drug effects; Epithelial Cells / enzymology; Epithelial Cells / ultrastructure; Gene Expression / drug effects; Gene Expression Regulation / drug effects; Hypoxia-Inducible Factor 1, alpha Subunit / genetics; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; MAP Kinase Signaling System; Metal Nanoparticles; Mitogen-Activated Protein Kinases / metabolism; Nickel / metabolism; Nickel / pharmacology; Phosphorylation; Platelet-Derived Growth Factor / physiology; Pleura / cytology; Protein Processing, Post-Translational; Rats; Receptors, Platelet-Derived Growth Factor / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Over-expression of human endosulfatase-1 exacerbates cadmium-induced injury to transformed human lung cells in vitro

TOXICOLOGY AND APPLIED PHARMACOLOGY, 265(1), 27–42.

By: H. Zhang n, D. Newman n, J. Bonner n & P. Sannes n

co-author countries: United States of America 🇺🇸
author keywords: Cadmium; HSulf-1; Lung epithelial injury; 6-O-sulfate
MeSH headings : Adenoviridae / genetics; Apoptosis / drug effects; Blotting, Western; Cadmium / toxicity; Cell Count; Cell Line, Tumor; Cell Survival / drug effects; Cell Transformation, Neoplastic / drug effects; Coloring Agents; Down-Regulation / drug effects; Heparan Sulfate Proteoglycans / pharmacology; Humans; In Situ Nick-End Labeling; Lac Operon / genetics; Lung / pathology; Polymerase Chain Reaction; Respiratory Mucosa / pathology; Sulfotransferases / biosynthesis; Sulfotransferases / physiology; Tetrazolium Salts; Thiazoles; Transduction, Genetic; Up-Regulation / drug effects
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung

ACS NANO, 5(12), 9772–9787.

By: X. Wang*, T. Xia*, S. Ntim*, Z. Ji*, S. Lin*, H. Meng*, C. Chung*, S. George* ...

co-author countries: United States of America 🇺🇸
author keywords: multiwalled carbon nanotubes (MWCNTs); dispersion; TGF-beta 1; PDGF-AA; IL-1 beta; collagen; lung fibrosis
MeSH headings : Animals; Biomarkers / metabolism; Cytokines / metabolism; Dose-Response Relationship, Drug; Lung / drug effects; Lung / metabolism; Mice; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018

2011 review

PULMONARY ENDPOINTS (LUNG CARCINOMAS AND ASBESTOSIS) FOLLOWING INHALATION EXPOSURE TO ASBESTOS

[Review of ]. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS, 14(1-4), 76–121.

By: B. Mossman*, M. Lippmann*, T. Hesterberg*, K. Kelsey*, A. Barchowsky* & J. Bonner n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Asbestos / administration & dosage; Asbestos / chemistry; Asbestos / pharmacokinetics; Asbestos / toxicity; Asbestosis / metabolism; Biological Transport; Body Burden; Carcinogens, Environmental / administration & dosage; Carcinogens, Environmental / chemistry; Carcinogens, Environmental / pharmacokinetics; Carcinogens, Environmental / toxicity; Carcinoma / chemically induced; Carcinoma / genetics; Carcinoma / metabolism; Chemical Phenomena; Humans; Inhalation Exposure / adverse effects; Lung / drug effects; Lung / metabolism; Lung Neoplasms / chemically induced; Lung Neoplasms / genetics; Lung Neoplasms / metabolism; Mineral Fibers / analysis; Mineral Fibers / toxicity; Mutagens / administration & dosage; Mutagens / chemistry; Mutagens / pharmacokinetics; Mutagens / toxicity; Particulate Matter / administration & dosage; Particulate Matter / chemistry; Particulate Matter / pharmacokinetics; Particulate Matter / toxicity; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Bacterial Lipopolysaccharide Enhances PDGF Signaling and Pulmonary Fibrosis in Rats Exposed to Carbon Nanotubes

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 43(2), 142–151.

By: M. Cesta n, J. Ryman-Rasmussen*, D. Wallace, T. Masinde, G. Hurlburt, A. Taylor, J. Bonner*

co-author countries: United States of America 🇺🇸
author keywords: carbon nanotubes; inflammation; lipopolysaccharide; fibrosis; growth factors
MeSH headings : Animals; Bacteria / metabolism; Fibroblasts / metabolism; Fibrosis; Inflammation; Lipopolysaccharides / metabolism; Macrophages / metabolism; Male; Nanotechnology / methods; Nanotubes, Carbon / chemistry; Platelet-Derived Growth Factor / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor / metabolism; Signal Transduction; Soot / chemistry
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Respiratory syncytial virus infection reduces lung inflammation and fibrosis in mice exposed to vanadium pentoxide

RESPIRATORY RESEARCH, 11.

By: E. Turpin*, A. Antao-Menezes*, M. Cesta n, J. Mangum*, D. Wallace*, E. Bermudez*, J. Bonner n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cytokines / metabolism; Male; Mice; Mice, Inbred AKR; Pneumonia / chemically induced; Pneumonia / complications; Pneumonia / metabolism; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / complications; Pulmonary Fibrosis / metabolism; Respiratory Syncytial Virus Infections / complications; Respiratory Syncytial Virus Infections / metabolism; Vanadium Compounds
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 40(3), 349–358.

By: J. Ryman-Rasmussen*, E. Tewksbury, O. Moss, M. Cesta*, B. Wong & J. Bonner*

author keywords: carbon nanotubes; asthma; fibrosis; lung
MeSH headings : Administration, Inhalation; Aerosols; Animals; Asthma / chemically induced; Asthma / immunology; Asthma / pathology; Bronchoalveolar Lavage Fluid / cytology; Fibrosis / chemically induced; Fibrosis / immunology; Fibrosis / pathology; Humans; Interleukin-13 / immunology; Lung / cytology; Lung / immunology; Lung / pathology; Macrophages / cytology; Macrophages / metabolism; Male; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / adverse effects; Nanotubes, Carbon / ultrastructure; Ovalbumin / immunology; Particle Size; Platelet-Derived Growth Factor / immunology; Random Allocation; Transforming Growth Factor beta1 / immunology
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Inhaled carbon nanotubes reach the subpleural tissue in mice

NATURE NANOTECHNOLOGY, 4(11), 747–751.

By: J. Ryman-Rasmussen n, M. Cesta n, A. Brody n, J. Shipley-Phillips n, J. Everitt n, E. Tewksbury*, O. Moss*, B. Wong* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Aerosols / adverse effects; Animals; Immunity / drug effects; Inhalation Exposure / analysis; Male; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / adverse effects; Nanotubes, Carbon / ultrastructure; Pleura / drug effects; Pleura / immunology; Pleura / ultrastructure; Pulmonary Fibrosis / chemically induced
Source: Web Of Science
Added: August 6, 2018

2009 article

Nanoparticle-Mediated Drug Delivery and Pulmonary Hypertension

Bonner, J. C., Card, J. W., & Zeldin, D. C. (2009, May). HYPERTENSION, Vol. 53, pp. 751–753.

By: J. Bonner*, J. Card* & D. Zeldin*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
MeSH headings : Animals; Drug Delivery Systems; Hypertension, Pulmonary / drug therapy; NF-kappa B / antagonists & inhibitors; NF-kappa B / physiology; Nanoparticles / administration & dosage; Nanoparticles / toxicity; Nanotubes, Carbon; Oligodeoxyribonucleotides / administration & dosage; Rats
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 39(1), 45–52.

By: J. Voltz, J. Card, M. Carey, L. DeGraff, C. Ferguson, G. Flake, J. Bonner*, K. Korach, D. Zeldin

author keywords: fibrosis; bleomycin; sex; respiratory mechanics
MeSH headings : Animals; Bleomycin / toxicity; Collagen / metabolism; Dihydrotestosterone / pharmacology; Estradiol / deficiency; Female; Inflammation / chemically induced; Inflammation / physiopathology; Lung Compliance / drug effects; Lung Compliance / physiology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Ovariectomy; Polymerase Chain Reaction; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / physiopathology; RNA / genetics; Respiratory Function Tests; Sex Characteristics
Source: Web Of Science
Added: August 6, 2018

2008 review

Pulmonary applications and toxicity of engineered nanoparticles

[Review of ]. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 295(3), L400–L411.

By: J. Card, D. Zeldin*, J. Bonner* & E. Nestmann

author keywords: nanotechnology; nanomaterials; respiratory system; lung
MeSH headings : Animals; Drug Delivery Systems; Humans; Lung / drug effects; Lung / metabolism; Models, Biological; Nanoparticles / therapeutic use; Nanoparticles / toxicity; Nanotechnology; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018

2008 journal article

STAT-1 signaling in human lung fibroblasts is induced by vanadium pentoxide through an IFN-beta autocrine loop

JOURNAL OF IMMUNOLOGY, 180(6), 4200–4207.

By: A. Antao-Menezes*, E. Turpin*, P. Bost n, J. Ryman-Rasmussen n & J. Bonner n

co-author countries: United States of America 🇺🇸
MeSH headings : Autocrine Communication / drug effects; Autocrine Communication / immunology; Cell Line; Culture Media, Conditioned; Enzyme Inhibitors / pharmacology; Fibroblasts / drug effects; Fibroblasts / enzymology; Fibroblasts / immunology; Fibroblasts / metabolism; Humans; Hydrogen Peroxide / metabolism; Interferon-beta / physiology; Intracellular Fluid / drug effects; Intracellular Fluid / immunology; Intracellular Fluid / metabolism; Lung / drug effects; Lung / enzymology; Lung / immunology; Lung / metabolism; NADPH Oxidases / antagonists & inhibitors; NADPH Oxidases / physiology; Phosphorylation; Reactive Oxygen Species / metabolism; STAT1 Transcription Factor / metabolism; STAT1 Transcription Factor / physiology; Signal Transduction / drug effects; Signal Transduction / immunology; Vanadium Compounds / pharmacology; Xanthine Oxidase / physiology
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Lung Fibrotic Responses to Particle Exposure

Toxicologic Pathology, 35(1), 148–153.

By: J. Bonner*

co-author countries: United States of America 🇺🇸
author keywords: metals; endotoxin; oxidants; cytokines; growth factors
MeSH headings : Air Pollutants / adverse effects; Animals; Carbon / adverse effects; Cities; Coal Ash; Humans; Inhalation Exposure; Lung / drug effects; Lung / pathology; Particle Size; Particulate Matter / adverse effects; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / pathology; Urban Health; Vehicle Emissions / toxicity
Source: Crossref
Added: August 14, 2021

2005 journal article

Susceptibility of Signal Transducer and Activator of Transcription-1-Deficient Mice to Pulmonary Fibrogenesis

The American Journal of Pathology, 167(5), 1221–1229.

By: D. Walters*, A. Antao-Menezes*, J. Ingram*, A. Rice*, A. Nyska*, Y. Tani*, S. Kleeberger*, J. Bonner*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bleomycin / toxicity; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen / analysis; Disease Models, Animal; Epidermal Growth Factor / pharmacology; Fibroblasts / pathology; Growth Inhibitors / pharmacology; Hydroxyproline / analysis; Interferon-gamma / pharmacology; Lung / drug effects; Lung / pathology; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3 / metabolism; Phosphorylation; Platelet-Derived Growth Factor / pharmacology; Pulmonary Fibrosis / genetics; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / physiopathology; STAT1 Transcription Factor / genetics; STAT1 Transcription Factor / physiology; STAT3 Transcription Factor / metabolism; Thymidine / metabolism
Source: Crossref
Added: August 28, 2020

2004 journal article

Regulation of PDGF and its receptors in fibrotic diseases

Cytokine & Growth Factor Reviews, 15(4), 255–273.

By: J. Bonner*

co-author countries: United States of America 🇺🇸
author keywords: PDGF; fibrosis; lung; liver; kidney
MeSH headings : Animals; Fibroblasts / metabolism; Fibrosis / pathology; Gene Expression Regulation; Humans; Inflammation / pathology; Interleukin-1 / metabolism; Kidney / pathology; Liver / pathology; Lung / pathology; Models, Biological; Muscles / pathology; Platelet-Derived Growth Factor / metabolism; Platelet-Derived Growth Factor / physiology; Protein Isoforms; Receptor, Platelet-Derived Growth Factor alpha / metabolism; Receptor, Platelet-Derived Growth Factor beta / metabolism; Scleroderma, Systemic / pathology; Signal Transduction; Tissue Distribution; Transforming Growth Factor beta / metabolism; Transforming Growth Factor beta1
Source: Crossref
Added: August 14, 2021

2001 article

Autocrine production of TGFa mediates interleukin 13-induced proliferation of human airway epithelial cells during development of a mucous phenotype in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A738.

By: B. Booth, J. Bonner, K. Adler & L. Martin

Source: NC State University Libraries
Added: August 6, 2018

2001 chapter

Interleukin-13 induced mucous cell hyperplasia in airway epithelium.

In Cilia and mucus: from development to respiratory disease. (pp. 253–263).

By: L. Martin, M. Macchione, J. Bonner, B. Booth, N. Akley & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Induction of heparin-binding epidermal growth factor (HB-EGF) mRNA in normal human bronchial epithelial cells by metal-induced oxidative stress.

American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A149.

By: J. Bonner, L. Zhang, P. Sannes, L. Martin, W. Gladwell, J. Koo, T. Gray, K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Interaction of TGF? and EGF receptor mediates IL-13 induced mucous cell hyperplasia in human airway epithelium in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A779.

By: L. Martin, J. Bonner, M. Macchione, B. Booth, N. Akley & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1999 article

Normal human bronchial epithelial cells produce heparin-binding epidermal growth factor (HB-EGF), a mitogen for human lung fibroblasts in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A508.

By: L. Zhang, K. Adler, P. Sannes & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

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