Center for Environmental and Health Effects of PFAS

Works Published in 2012

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Displaying works 81 - 100 of 115 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 journal article

Anchoring Ethinylestradiol Induced Gene Expression Changes with Testicular Morphology and Reproductive Function in the Medaka

PLOS ONE, 7(12).

By: H. Miller*, B. Clark*, D. Hinton*, A. Whitehead*, S. Martin n, K. Kwok*, S. Kullman n

MeSH headings : Animals; Breeding; Estrogens / toxicity; Ethinyl Estradiol / toxicity; Male; Oligonucleotide Array Sequence Analysis; Oryzias / anatomy & histology; Oryzias / genetics; Oryzias / physiology; Reproduction / drug effects; Reproduction / genetics; Species Specificity; Testis / anatomy & histology; Testis / drug effects; Testis / metabolism; Testis / physiology; Time Factors; Transcriptome / drug effects
TL;DR: It is demonstrated that a 14 day exposure to EE2 induced impaired male reproductive capacity and time- and dose-dependent alterations in testicular morphology and gene expression, highlighting the importance of anchoring global gonadal gene expression changes with morphology and ultimately with tissue/organ function. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Improved methodology to assess modification and completion of landfill gas management in the aftercare period

WASTE MANAGEMENT, 32(12), 2364–2373.

By: J. Morris*, M. Crest*, M. Barlaz n, K. Spokas*, A. Akerman & L. Yuan*

author keywords: Post-closure care; Aftercare; Landfill gas; Methane; Completion
MeSH headings : Air Pollutants / chemistry; Environmental Monitoring; France; Gases; Methane; Refuse Disposal; Time Factors
TL;DR: The improved gas module for theEPCC methodology emphasizes the reduction or elimination of fugitive methane by considering the methane oxidation capacity of the cover system, and allows for the installation of biologically active covers or other features designed to enhance methane oxidation. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 article

BioCreative-2012 Virtual Issue

Wu, C. H., Arighi, C. N., Cohen, K. B., Hirschman, L., Krallinger, M., Lu, Z. Y., … al. (2012, December 5). DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: C. Wu*, C. Arighi*, K. Cohen*, L. Hirschman*, M. Krallinger*, Z. Lu*, C. Mattingly*, A. Valencia* ...

MeSH headings : Congresses as Topic; Cooperative Behavior; Data Mining; Databases, Genetic; Periodicals as Topic; Workflow
TL;DR: This DATABASE virtual issue captures the major results from the BioCreative-2012 Workshop on Interactive Text Mining in the Biocuration Workflow and is the fifth special issue devoted to Biocreative. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Targeted journal curation as a method to improve data currency at the Comparative Toxicogenomics Database

Database-The Journal of Biological Databases and Curation.

By: A. Davis, R. Johnson, K. Lennon-Hopkins, D. Sciaky, M. Rosenstein, T. Wiegers, C. Mattingly

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Characteristics of competitive adsorption between 2-methylisoborneol and natural organic matter on superfine and conventionally sized powdered activated carbons

WATER RESEARCH, 46(15), 4741–4749.

By: Y. Matsui*, T. Yoshida*, S. Nakao*, D. Knappe n & T. Matsushita*

Contributors: Y. Matsui*, T. Yoshida*, S. Nakao*, D. Knappe n & T. Matsushita*

author keywords: PAC; Particle size; Sub-micrometer; Competitive adsorption; Humic substance; Taste and odor
MeSH headings : Adsorption; Camphanes / chemistry; Carbon / chemistry; Powders
TL;DR: Results of this study show that adsorption competition between NOM and MIB did not increase when NOM uptake increased due to carbon size reduction; i.e., the increased Nom uptake by SPAC did not result in a decrease in MIB adsorptive capacity beyond that obtained as a result of NOM adsor adaptation by PAC. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 review

Analytical strategies for the global quantification of intact proteins

[Review of ]. AMINO ACIDS, 43(3), 1109–1117.

By: T. Collier n & D. Muddiman n

author keywords: Proteomics; Intact proteins; Quantitation; Mass spectrometry
MeSH headings : Animals; Humans; Mass Spectrometry; Proteome / chemistry; Proteome / isolation & purification; Proteome / metabolism; Proteomics; Staining and Labeling; Two-Dimensional Difference Gel Electrophoresis
TL;DR: Techniques contained in this review include the more traditional and widely employed methodology of differential gel electrophoresis and more recently developed mass spectrometry-based techniques including metabolic labeling, chemical labeling, and label-free methodologies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Peptide Production and Decay Rates Affect the Quantitative Accuracy of Protein Cleavage Isotope Dilution Mass Spectrometry (PC-IDMS)

MOLECULAR & CELLULAR PROTEOMICS, 11(9), 814–823.

MeSH headings : Indicator Dilution Techniques; Isotope Labeling; Mass Spectrometry; Peptide Biosynthesis; Peptides / analysis; Peptides / chemistry; Peptides / metabolism; Populus / enzymology; Populus / metabolism; Proteolysis; Xylem / enzymology
TL;DR: It is concluded that the instability of peptides can often significantly bias the protein quantities measured in protein cleavage isotope dilution mass spectrometry-based assays and suggest peptide stability be made a priority when selecting peptides to use for quantification. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Functional redundancy of the two 5-hydroxylases in monolignol biosynthesis of Populus trichocarpa: LC-MS/MS based protein quantification and metabolic flux analysis

PLANTA, 236(3), 795–808.

By: J. Wang n, C. Shuford n, Q. Li n, J. Song n, Y. Lin n, Y. Sun n, H. Chen n, C. Williams n ...

author keywords: Lignin; Syringyl lignin; Angiosperm; Kinetics; Subcellular localization
MeSH headings : Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hydroxylation; Kinetics; Lignin / analysis; Lignin / biosynthesis; Mixed Function Oxygenases / metabolism; Plants, Genetically Modified; Populus / metabolism; Xylem / enzymology; Yeasts / metabolism
TL;DR: The combination of genetic analysis, absolute protein quantitation-based enzyme kinetics, homologous CPR specificity, SNP characterization, and ER localization provides a more rigorous basis for a comprehensive systems understanding of 5-hydroxylation in lignin biosynthesis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Abiotic and Biotic Compression of Municipal Solid Waste

JOURNAL OF GEOTECHNICAL AND GEOENVIRONMENTAL ENGINEERING, 138(8), 877–888.

author keywords: Municipal solid waste; Settlement; Bioreactor landfills; Methane generation; Leachate; Recirculation; Biocompression
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Surface modifications on InAs decrease indium and arsenic leaching under physiological conditions

APPLIED SURFACE SCIENCE, 261, 842–850.

By: S. Jewett*, J. Yoder n & A. Ivanisevic n

author keywords: InAs; Zebrafish; Toxicity; Passivation; Surface modifications; ICP-MS
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Ranking Transitive Chemical-Disease Inferences Using Local Network Topology in the Comparative Toxicogenomics Database

PLOS ONE, 7(11).

By: B. King*, A. Davis n, M. Rosenstein*, T. Wiegers n & C. Mattingly n

MeSH headings : Cluster Analysis; Databases, Factual; Drug-Related Side Effects and Adverse Reactions / genetics; Gene Regulatory Networks; Humans; Protein Interaction Mapping; Toxicogenetics / methods
TL;DR: A statistic to score and rank inferences based on the topology of the local network consisting of the chemical, disease and each of the genes used to make an inference is implemented, which uniquely takes into account the number of common neighbors and the connectivity of each entity involved. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Multivariate regression as an energy assessment tool in early building design

BUILDING AND ENVIRONMENT, 57, 165–175.

By: J. Hygh, J. DeCarolis*, D. Hill n & S. Ranjithan

author keywords: EnergyPlus; Monte Carlo simulation; Multivariate regression; Sensitivity analysis
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

In-Depth Analysis of the Magnaporthe oryzae Conidial Proteome

JOURNAL OF PROTEOME RESEARCH, 11(12), 5827–5835.

By: E. Gokce n, W. Franck n, Y. Oh n, R. Dean n & D. Muddiman n

author keywords: proteomics; mass spectrometry; Magnaporthe oryzae; FASP; statistical tests; differential protein expression
MeSH headings : Cell Nucleus / chemistry; Chemical Fractionation / methods; Chromatography, Liquid / methods; Cytoplasm / chemistry; Fungal Proteins / analysis; Fungal Proteins / chemistry; Magnaporthe / chemistry; Mass Spectrometry / methods; Nanotechnology; Nuclear Proteins / analysis; Nuclear Proteins / chemistry; Peptides / analysis; Peptides / chemistry; Proteome / analysis; Proteome / chemistry; Reproducibility of Results; Sensitivity and Specificity; Spores, Fungal / chemistry; Time Factors
TL;DR: The identification of 2912 conidial proteins at a 1% protein false discovery rate (FDR) is reported and the most extensive study performed on M. oryzae conidia to date is presented, suggesting the detected proteins build a representative portion of the predicted proteome. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Dietary (periphyton) and aqueous Zn bioaccumulation dynamics in the mayfly Centroptilum triangulifer

ECOTOXICOLOGY, 21(8), 2288–2296.

By: K. Kim n, D. Funk* & D. Buchwalter n

author keywords: Zinc; Bioaccumulation; Periphyton; Mayfly; Biodynamic modeling
MeSH headings : Animals; Environmental Monitoring / methods; Eukaryota / metabolism; Female; Food Chain; Insecta / drug effects; Insecta / metabolism; Insecta / physiology; Larva / drug effects; Larva / metabolism; Larva / physiology; Ovum / drug effects; Ovum / metabolism; Ovum / physiology; Zinc / metabolism
TL;DR: Both life cycle and biodynamic modeling approaches point towards diet being the primary route of Zn bioaccumulation in this mayflies, revealing that mayflies lose significant Zn before reaching adulthood. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Coordination-Driven Self-Assembly of Charged and Neutral Dendritic Tetrakis(ferrocenyl) Rhomboids

ORGANOMETALLICS, 31(20), 7241–7247.

UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Systematic Comparison of Reverse Phase and Hydrophilic Interaction Liquid Chromatography Platforms for the Analysis of N-Linked Glycans

ANALYTICAL CHEMISTRY, 84(19), 8198–8206.

By: S. Walker n, B. Carlisle n & D. Muddiman n

MeSH headings : Chromatography, Reverse-Phase; Hydrophobic and Hydrophilic Interactions; Mass Spectrometry; Polysaccharides / analysis
TL;DR: The data presented show that separation of derivatized N-linked glycans by reverse phase chromatography significantly out-performs traditional separation of native or derivatization glycansBy hydrophilic interaction chromatography. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Enhanced Simulation-Optimization Approach Using Surrogate Modeling for Solving Inverse Problems

ENVIRONMENTAL FORENSICS, 13(4), 348–363.

By: B. Mirghani n, E. Zechman n, R. Ranjithan n & G. Mahinthakumar n

author keywords: artificial numeral network; genetic algorithms; groundwater modeling; inverse problems; simulation-optimization; surrogate modeling
TL;DR: This study investigates and discusses groundwater system characterization problem utilizing surrogate modeling, a technique utilized to solve inverse problems by formulating them as an optimization model, where evolutionary computation algorithms are used to perform the search. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Evidence for Complex Molecular Architectures for Solvent-Extracted Lignins

ACS MACRO LETTERS, 1(5), 568–573.

By: S. Harton, S. Pingali, G. Nunnery, D. Baker*, S. Walker n, D. Muddiman n, T. Koga*, T. Rials*, V. Urban, P. Langan

Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Providing the Missing Link: the Exposure Science Ontology ExO

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 46(6), 3046–3053.

MeSH headings : Environmental Exposure / analysis; Environmental Health; Environmental Pollutants; Humans; Models, Theoretical
TL;DR: Development of an Exposure Ontology, ExO, designed to address this information gap by facilitating centralization and integration of exposure data and intended to link exposure science and diverse environmental health disciplines including toxicology, epidemiology, disease surveillance, and epigenetics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Divalent metal (Ca, Cd, Mn, Zn) uptake and interactions in the aquatic insect Hydropsyche sparna

JOURNAL OF EXPERIMENTAL BIOLOGY, 215(9), 1575–1583.

By: M. Poteat n, M. Diaz-Jaramillo* & D. Buchwalter n

author keywords: aquatic insect; competition; inhibitors; metals; transport
MeSH headings : Animals; Binding, Competitive; Biological Transport; Cadmium / pharmacokinetics; Calcium / chemistry; Calcium / pharmacokinetics; Cations; Cell Membrane / metabolism; Dose-Response Relationship, Drug; Eosine Yellowish-(YS) / chemistry; Insecta / drug effects; Kinetics; Manganese / pharmacokinetics; Metals / pharmacokinetics; Models, Biological; Nifedipine / pharmacology; Verapamil / pharmacology; Zinc / pharmacokinetics
TL;DR: Evidence is provided for at least two transport systems for both Zn and Cd, the first of which operates at concentrations below 0.8 μmol l–1 (and is fully saturable for Zn), and no signs of saturation of a second lower affinity transport system at concentrations up to 8.9 μmolL–1. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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