Works Published in 2012
Displaying works 521 - 540 of 613 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Merging pharmacometabolomics with pharmacogenomics using ‘1000 Genomes’ single-nucleotide polymorphism imputation
Pharmacogenetics and Genomics, 22(4), 247–253.
author keywords: 1000 Genomes; HapMap; imputation; major depressive disorder; pharmacometabolomics; pharmacogenomics; selective serotonin reuptake inhibitors; tag single-nucleotide polymorphisms
MeSH headings : Citalopram / adverse effects; Citalopram / therapeutic use; Depressive Disorder / drug therapy; Depressive Disorder / genetics; Genome-Wide Association Study / methods; Glycine / biosynthesis; Glycine / genetics; Glycine / metabolism; Glycine Dehydrogenase / genetics; HapMap Project; Haplotypes; Humans; Metabolic Networks and Pathways / genetics; Metabolomics; Pharmacogenetics; Polymorphism, Single Nucleotide / genetics; Selective Serotonin Reuptake Inhibitors / metabolism
TL;DR:
The results indicate that the use of GWAS data to impute SNPs for genes in pathways identified by other ‘omics’ approaches makes it possible to rapidly and cost efficiently identify SNP markers to ‘broaden’ and accelerate pharmacogenomic studies.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2012 journal article
Identification of Nitrite-Reducing Bacteria Using Sequential mRNA Fluorescence In Situ Hybridization and Fluorescence-Assisted Cell Sorting
MICROBIAL ECOLOGY, 64(1), 256–267.
MeSH headings : Bacteria / enzymology; Bacteria / genetics; Bacteria / isolation & purification; Bacteria / metabolism; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Flow Cytometry / methods; In Situ Hybridization, Fluorescence / methods; Nitrite Reductases / genetics; Nitrite Reductases / metabolism; Nitrites / metabolism; Oxidation-Reduction; Pseudomonas stutzeri / genetics; Pseudomonas stutzeri / isolation & purification; Pseudomonas stutzeri / metabolism; Sewage / chemistry; Sewage / microbiology
TL;DR:
The molecular approach described can be useful as a tool to help address the longstanding challenge of linking function to identity in natural and engineered habitats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 article
Graphic Novels and Comics in Libraries and Archives: Essays on Readers, Research, History, and Cataloging.
Orcutt, D. (2012, April). LIBRARY RESOURCES & TECHNICAL SERVICES, Vol. 56, pp. 116–117.
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Evaluation of a quantitative H2S MPN test for fecal microbes analysis of water using biochemical and molecular identification
WATER RESEARCH, 46(6), 1693–1704.
author keywords: Quantitative H2S test; Microbial water quality; TRFLP; Fecal indicator
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Cell Culture Techniques; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Environmental Monitoring / methods; Feces / microbiology; Genome, Bacterial / genetics; Hydrogen Sulfide / pharmacology; Lakes / microbiology; North Carolina; Polymorphism, Restriction Fragment Length; Rain / microbiology; Software; Software Design; Species Specificity; Universities; Water; Water Microbiology; Water Wells / microbiology
TL;DR:
Overall, it was shown that water samples testing positive for H(2)S bacteria also had bacteria of likely fecal origin and waters containing fecal pathogens also were positive for the test, further document the validity of the H( 2)S test for detecting and quantifying fecal contamination of water.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Effect of sexual recombination on population diversity in aflatoxin production by Aspergillus flavus and evidence for cryptic heterokaryosis
MOLECULAR ECOLOGY, 21(6), 1453–1476.
author keywords: array comparative genome hybridization; biological control; heritability; multilocus sequence typing; non-Mendelian segregation; vegetative compatibility group
MeSH headings : Aflatoxins / biosynthesis; Aspergillus flavus / genetics; Aspergillus flavus / metabolism; Comparative Genomic Hybridization; Fungal Proteins / genetics; Genes, Mating Type, Fungal / genetics; Genetic Variation; Karyotyping; Molecular Sequence Data; Multigene Family; Recombination, Genetic; Sequence Analysis, DNA
TL;DR:
Results from experimental matings indicate that sexual recombination is driving genetic and functional hyperdiversity in A. flavus, and have significant implications for managing AF contamination of crops and for improving biocontrol strategies using nonaflatoxigenic strains of A. Flavus.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Differential expression of genes characterizing myofibre phenotype
ANIMAL GENETICS, 43(3), 298–308.
author keywords: gene expression; microarray; muscle phenotype; turkey
MeSH headings : Age Factors; Animals; DNA, Complementary / genetics; Gene Expression Profiling; Gene Expression Regulation; Male; Meat; Muscle Fibers, Skeletal / metabolism; Muscle Proteins / genetics; Muscle Proteins / metabolism; Oligonucleotide Array Sequence Analysis; Phenotype; Real-Time Polymerase Chain Reaction; Turkeys / genetics; Turkeys / growth & development; Turkeys / metabolism
TL;DR:
The gene analysis revealed that phenotypically 'red' BF muscle has high expression of glycolytic genes usually associated with the 'white' muscle phenotype, which may have large implications in muscle-type-related disorders and improvement of muscle quality in agricultural species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Comparative Genomics of Duplicate gamma-Glutamyl Transferase Genes in Teleosts: Medaka (Oryzias latipes), Stickleback (Gasterosteus aculeatus), Green Spotted Pufferfish (Tetraodon nigroviridis), Fugu (Takifugu rubripes), and Zebrafish (Danio rerio)
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, 318B(1), 35–49.
MeSH headings : Amino Acid Sequence; Animals; Female; Fishes / classification; Fishes / genetics; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genes, Duplicate / genetics; Genomics; Larva; Male; Molecular Sequence Data; Phylogeny; Sequence Alignment; Synteny; gamma-Glutamyltransferase / chemistry; gamma-Glutamyltransferase / genetics
TL;DR:
Examination of multiple paralogous genes of γ-glutamyl transferase (GGT) in several distantly related teleost species including medaka, stickleback, green spotted pufferfish, fugu, and zebrafish demonstrates that multiple GGT genes have been retained within teleost genomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 article
A reexamination of molecular markers for use in marker-assisted breeding in tomato (Retracted article. See vol. 194, pg. 149, 2013)
Panthee, D. R., & Foolad, M. R. (2012, March). EUPHYTICA, Vol. 184, pp. 165–179.
author keywords: Disease resistance; Marker validation; Molecular breeding; Molecular markers; Solanum lycopersicum
TL;DR:
The utility of available markers for several major disease resistance traits in tomato is examined by testing them in a number of breeding lines and commercial cultivars with known resistance/susceptibility responses, finding that 19 of the 37 markers examined were informative.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
A model of axonal transport drug delivery
CENTRAL EUROPEAN JOURNAL OF PHYSICS, 10(2), 320–328.
author keywords: targeted drug delivery; neurons; molecular motors; axonal transport; numerical modeling
TL;DR:
A model of targeted drug delivery by means of active (motor-driven) axonal transport is developed and an analytical solution of the coupled system of transient equations describing conservations of these two populations of PACs is obtained by using Laplace transform.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
A <i>de novo</i> transcriptome assembly of <i>Lucilia sericata</i> (Diptera: Calliphoridae) with predicted alternative splices, single nucleotide polymorphisms and transcript expression estimates
Insect Molecular Biology, 21(2), 205–221.
author keywords: Drosophila; Lucilia; transcriptome; de novo assembly; alternative splice; transposable element
MeSH headings : Alternative Splicing; Animals; Culicidae / genetics; DNA Transposable Elements; Diptera / genetics; Diptera / growth & development; Diptera / metabolism; Drosophila melanogaster / genetics; Female; Gene Expression; Genome, Insect; Male; Molecular Conformation; Multigene Family; Polymorphism, Single Nucleotide; Transcriptome
TL;DR:
The assembly of the transcriptome was carried out in a manner that enabled identification of putative single nucleotide polymorphisms (SNPs) and alternative splices, and that provided expression estimates for various life history stages and for salivary tissue.
(via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2012 journal article
Widespread inbreeding and unexpected geographic patterns of genetic variation in eastern hemlock (Tsuga canadensis), an imperiled North American conifer
CONSERVATION GENETICS, 13(2), 475–498.
author keywords: Phylogeography; Pleistocene; Migration; Population genetics; Microsatellite; Bottleneck
TL;DR:
Efforts to conserve eastern hemlock genetic material should emphasize the capture of broad adaptability that occurs across the geographic range of the species, as well as genetic variability within regions with the highest allelic richness and heterozygosity, such as the Southern Appalachians and New England, and within disjunct populations that are genetically distinct.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Two Novel Type II Restriction-Modification Systems Occupying Genomically Equivalent Locations on the Chromosomes of Listeria monocytogenes Strains
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(8), 2623–2630.
MeSH headings : Bacteriophages / growth & development; Chromosomes, Bacterial; Cluster Analysis; DNA Restriction-Modification Enzymes / genetics; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Bacterial / metabolism; Electrophoresis, Gel, Pulsed-Field; Listeria monocytogenes / classification; Listeria monocytogenes / enzymology; Listeria monocytogenes / genetics; Listeria monocytogenes / virology; Molecular Sequence Data; Molecular Typing; Sequence Analysis, DNA; Synteny
TL;DR:
Among the sequenced Listeria phages, lytic phages possessed significantly fewer recognition sites for these RM systems than lysogenic phage sequence content, suggesting that in lyticphages sequence content evolved toward reduced susceptibility to such RM systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 review
Stochasticity in Sexual Selection Enables Divergence: Implications for Moth Pheromone Evolution
[Review of ]. EVOLUTIONARY BIOLOGY, 39(2), 271–281.
author keywords: Genetic drift; Moth; Population genetic model; Sexual selection; Speciation; Stochasticity
TL;DR:
The role that stochastic changes in sexual selection strength plays in the shift of predominance between pairs of preferences and traits within a single population is examined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Redispersal of seeds by a keystone ant augments the spread of common wildflowers
ACTA OECOLOGICA-INTERNATIONAL JOURNAL OF ECOLOGY, 40, 31–39.
author keywords: Redispersal; Myrmecochory; Aphaenogaster rudis; Population spread rate; Plant benefits; Temperate forest
TL;DR:
A novel seed-tracking technique is used to quantify secondary dispersal of seeds from the nest into the surrounding leaf litter by the keystone seed-dispersing ant, Aphaenogaster rudis, and suggests myrmecochory benefits plants in eastern North American forests by increasing the distance between the seed and parent plant and reducing competition among siblings.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
QUANTIFYING EFFICACY AND AVOIDANCE BEHAVIOR BY TAWNY MOLE CRICKETS (ORTHOPTERA: GRYLLOTALPIDAE: SCAPTERISCUS VICINUS) TO THREE SYNTHETIC INSECTICIDES
FLORIDA ENTOMOLOGIST, 95(1), 63–74.
author keywords: Scapteriscus; vicinus; avoidance; insecticide control; management
TL;DR:
These studies confirm that mole crickets avoid an area treated with insecticide and emphasize the importance of appropriate timing of insecticides to achieve effective control of mole cricket control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Purine Biosynthesis Mutants (purA and purB) of Serotype 4b Listeria monocytogenes Are Severely Attenuated for Systemic Infection in Intragastrically Inoculated A/J Mice
FOODBORNE PATHOGENS AND DISEASE, 9(5), 480–486.
MeSH headings : Adenylosuccinate Synthase / genetics; Adenylosuccinate Synthase / metabolism; Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Translocation; Caco-2 Cells; Female; Gallbladder / microbiology; Gastric Juice / chemistry; Gastroenteritis / microbiology; Gastroenteritis / physiopathology; Humans; Intestinal Mucosa / microbiology; Isoenzymes / genetics; Isoenzymes / metabolism; Listeria monocytogenes / genetics; Listeria monocytogenes / metabolism; Listeria monocytogenes / pathogenicity; Listeria monocytogenes / physiology; Listeriosis / microbiology; Listeriosis / physiopathology; Liver / microbiology; Mice; Mice, Inbred A; Microbial Viability; Mutant Proteins / metabolism; Purines / biosynthesis; Spleen / microbiology; Virulence
TL;DR:
It is demonstrated that purA and purB transposon mutants of serotype 4b Listeria monocytogenes were severely impaired in their ability to colonize the gastrointestinal tract and cause systemic infection of the spleen, liver, and gallbladder following intragastric inoculation of A/J mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Phylogenetic Analysis and Classification of the Fungal bHLH Domain
MOLECULAR BIOLOGY AND EVOLUTION, 29(5), 1301–1318.
author keywords: bHLH; fungal; phylogeny; discriminant; analysis
MeSH headings : Amino Acid Sequence; Ascomycota / genetics; Basidiomycota / genetics; Decision Trees; Discriminant Analysis; Fungal Proteins / chemistry; Fungal Proteins / classification; Fungal Proteins / genetics; Genome, Fungal; Helix-Loop-Helix Motifs / genetics; Models, Biological; Molecular Sequence Annotation; Molecular Sequence Data; Phylogeny; Sensitivity and Specificity
TL;DR:
The phylogenetic relationship of 490 fungal-specific bHLH containing proteins from 55 whole genome projects composed of 49 Ascomycota and 6 Basidiomycota organisms was obtained and evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Longitudinal study comparing the dynamics of Clostridium difficile in conventional and antimicrobial free pigs at farm and slaughter
VETERINARY MICROBIOLOGY, 157(1-2), 172–178.
author keywords: Clostridium difficile; Antimicrobial resistance; Swine; Toxinotyping; Toxins; Farm; Slaughter
MeSH headings : Animal Husbandry / methods; Animals; Anti-Bacterial Agents / administration & dosage; Clostridioides difficile / classification; Clostridioides difficile / drug effects; Clostridioides difficile / isolation & purification; Drug Resistance, Multiple, Bacterial; Longitudinal Studies; Microbial Sensitivity Tests; Prevalence; Sus scrofa / microbiology; Swine / microbiology; Swine Diseases / microbiology
TL;DR:
It is concluded that the unique production practices employed in conventional and ABF production systems have no impact on the pathogen population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Longitudinal Study of the Persistence of Antimicrobial-Resistant Campylobacter Strains in Distinct Swine Production Systems on Farms, at Slaughter, and in the Environment
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(8), 2698–2705.
MeSH headings : Animal Husbandry; Animal Structures / microbiology; Animals; Anti-Bacterial Agents / pharmacology; Campylobacter coli / drug effects; Campylobacter coli / isolation & purification; Campylobacter jejuni / drug effects; Campylobacter jejuni / isolation & purification; Drug Resistance, Bacterial; Environmental Microbiology; Feces / microbiology; Longitudinal Studies; Microbial Sensitivity Tests; Swine / microbiology
TL;DR:
The results highlight the persistence and dissemination of AR Campylobacter from farm to slaughter in ABF and conventionally raised pigs and their environments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Influence of patch size and shape on occupancy by shrubland birds
Condor, 14(2), 268–278.
Source: NC State University Libraries
Added: August 6, 2018
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