Works Published in 2016
Displaying works 181 - 200 of 254 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Utilizing Viral Nanoparticle/Dendron Hybrid Conjugates in Photodynamic Therapy for Dual Delivery to Macrophages and Cancer Cells
Bioconjugate Chemistry, 27(5), 1227–1235.
Contributors: A. Wen, K. Lee, P. Cao, K. Pangilinan, B. Carpenter n, P. Lam, F. Veliz, R. Ghiladi n , R. Advincula, N. Steinmetz
MeSH headings : Animals; Comovirus / chemistry; Dendrimers / chemistry; Drug Carriers / chemistry; Macrophages / metabolism; Melanoma, Experimental / pathology; Mice; Nanoparticles / chemistry; Photochemotherapy; Photosensitizing Agents / chemistry; Photosensitizing Agents / metabolism; RAW 264.7 Cells
TL;DR:
Overall, effective elimination of both macrophage and tumor cells at low micromolar concentrations of the photosensitizer when delivered with the CPMV bioconjugate is demonstrated, thereby potentially improving melanoma treatment.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Single molecule targeted sequencing for cancer gene mutation detection
Scientific Reports, 6.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Nondirected C-H Activation of Arenes with Cp*Ir(III) Acetate Complexes: An Experimental and Computational Study
ORGANOMETALLICS, 35(15), 2435–2445.
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2016 journal article
Microscopic Movement of Slow-Diffusing Nanoparticles in Cylindrical Nanopores Studied with Three-Dimensional Tracking
ANALYTICAL CHEMISTRY, 88(10), 5122–5130.
TL;DR:
This study shows that it is possible to differentiate slow diffusion in confined environments caused by different mechanisms, and that the particles in sticky pores are microscopically active by showing limited reduction of step sizes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
High Aspect Ratio Nanotubes Formed by Tobacco Mosaic Virus for Delivery of Photodynamic Agents Targeting Melanoma
ACS Biomaterials Science & Engineering, 2(5), 838–844.
Contributors: K. Lee, B. Carpenter n, A. Wen, R. Ghiladi n & N. Steinmetz
author keywords: viral nanoparticles; tobacco mosaic virus; photodynamic therapy; melanoma
TL;DR:
The delivery of a porphyrin-based photosensitizer encapsulated within a plant viral nanoparticle made use of the hollow, high aspect ratio nanotubes formed by the nucleoprotein components of tobacco mosaic virus to encapsulate the drug for delivery and targeting of cancer cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Development of a Highly Efficient Pretreatment Sequence for the Enzymatic Saccharification of Loblolly Pine Wood
ACS Sustainable Chemistry & Engineering, 4(7), 3669–3678.
Contributors: X. Du n, L. Lucia n & R. Ghiladi n
author keywords: Pretreatment; Softwood; Delamination; XRD; Phosphoric acid; Saccharification efficiency
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Broadband transient absorption study of photoexcitations in lead halide perovskites: Towards a multiband picture
PHYSICAL REVIEW B, 93(16).
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Alarms about structural alerts
GREEN CHEMISTRY, 18(16), 4348–4360.
TL;DR:
It is demonstrated that contrary to the common perception of QSAR models as "black boxes" they can be used to identify statistically significant chemical substructures (QSAR-based alerts) that influence toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Adsorption of copper on a γ-alumina support
Surface Science, 651, 22–27.
author keywords: Gamma alumina; Configuration interaction calculations; Copper adsorption
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2016 journal article
Vacancy-induced manganese vanadates and their potential application to Li-ion batteries
CHEMICAL COMMUNICATIONS, 52(47), 7509–7512.
TL;DR:
It is shown that vacancies created by ammonium ions and coordinating water molecules within the manganese vanadate crystal structure yield high-charge capacity, favorable rate capability, and long cycle life in Li-ion half-cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Trust, but Verify II: A Practical Guide to Chemogenomics Data Curation
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 56(7), 1243–1252.
MeSH headings : Consensus; Genomics; Quality Control; Quantitative Structure-Activity Relationship; Reproducibility of Results; Statistics as Topic / standards
TL;DR:
A chemical and biological data curation workflow that relies on existing cheminformatics approaches to flag, and when appropriate, correct possibly erroneous entries in large chemogenomics data sets is proposed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
TransOmic analysis of forebrain sections in Sp2 conditional knockout embryonic mice using IR-MALDESI imaging of lipids and LC-MS/MS label-free proteomics
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408(13), 3453–3474.
author keywords: IR-MALDESI; Proteomics; Lipidomics; Mass spectrometry imaging; Embryonic brain
MeSH headings : Animals; Chromatography, Liquid / methods; Lipids / analysis; Mass Spectrometry / methods; Mice; Mice, Knockout; Prosencephalon / embryology; Prosencephalon / metabolism; Sp2 Transcription Factor / genetics; Spectrophotometry, Infrared / methods; Transcriptome
TL;DR:
An integrated approach for systematic analysis of the “lipidome” in tissue revealed many specific changes to fundamental cellular processes and biosynthetic pathways in the cerebral cortices of Sp2-cKO embryos.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Synthesis of 1,2,4-Oxadiazoles via DDQ-Mediated Oxidative Cyclization of Amidoximes
Synthesis, 48(12), 1902–1909.
author keywords: oxidation; cyclization; heterocycles; radicals; medicinal chemistry
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2016 journal article
Second generation modifiers of colistin resistance show enhanced activity and lower inherent toxicity
TETRAHEDRON, 72(25), 3549–3553.
author keywords: Antibiotic adjuvant; 2-Aminoimidazole; Colistin; ESKAPE pathogens; Acinetobacter baumannii; Pseudomonas aeruginosa
TL;DR:
From these libraries, a new small molecule was identified that lowers the minimum inhibitory concentration of colistin by up to 32-fold greater than the parent compound while also displaying less inherent bacterial effect, thereby minimizing the likelihood of resistance evolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Photosensitizer-Embedded Polyacrylonitrile Nanofibers as Antimicrobial Non-Woven Textile
Nanomaterials, 6(4), 77.
Contributors: S. Stanley n, F. Scholle n, J. Zhu n, Y. Lu n, X. Zhang n , X. Situ n, R. Ghiladi n
author keywords: photodynamic inactivation; singlet oxygen; antibacterial; antiviral; photobiocidal; polyacrylonitrile; photosensitizer; porphyrin
TL;DR:
The results demonstrate the potential of photosensitizer-embedded polyacrylonitrile nanofibers to serve as scalable scaffolds for anti-infective or self-sterilizing materials against both bacteria and viruses when employing a photodynamic inactivation mode of action.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
9. Industry, Innovation and Infrastructure
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 review
Optimizing Mass Spectrometry Analyses: A Tailored Review on the Utility of Design of Experiments
[Review of ]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 27(5), 767–785.
author keywords: Design of experiments; Mass spectrometry; Tutorial; Optimization; Modeling
MeSH headings : Mass Spectrometry; Models, Statistical; Research Design
TL;DR:
This review provides a tutorial-like guide into the selection of DOE for MS experiments, the practices for modeling and optimization of response variables, and the available software tools that support DOE implementation in any laboratory.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Improving the analytical performance and versatility of paper spray mass spectrometry via paper microfluidics
ANALYST, 141(13), 4065–4073.
TL;DR:
Two paper-based microfluidic techniques, photolithography and wax patterning, were investigated for their potential to improve upon the sensitivity, reproducibility, and versatility of paper spray mass spectrometry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Design and characterization of a microfabricated hydrogen clearance blood flow sensor
JOURNAL OF NEUROSCIENCE METHODS, 267, 132–140.
author keywords: COMSOL Multiphysics; Electrolysis; Gas clearance; Photolithography; Platinum electrode
MeSH headings : Blood Chemical Analysis / instrumentation; Cerebrovascular Circulation / physiology; Computer Simulation; Electrodes, Implanted; Equipment Design; Finite Element Analysis; Hydrogen / analysis; Microtechnology; Norepinephrine / metabolism; Oxygen / analysis; Platinum; Reproducibility of Results
TL;DR:
Microfabrication allows for the high-throughput production of reproducible devices that are capable of monitoring deep brain CBF with sub-minute resolution, and can resolve physiological changes occurring on a shorter timescale than existing gas clearance measurements.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
1-Pyrenyl- and 3-Perylenyl-antimony(V) Derivatives for the Fluorescence Turn-On Sensing of Fluoride Ions in Water at Sub-ppm Concentrations
ORGANOMETALLICS, 35(11), 1854–1860.
Contributors: M. Hirai*, M. Myahkostupov n, F. Castellano n & F. Gabbaï *
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Whole-body Mass Spectrometry Imaging by Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI)
Journal of Visualized Experiments, 3(109).
author keywords: Bioengineering; Issue 109; Mass spectrometry imaging; IR-MALDESI; Tissue analysis; Whole-body imaging; Metabolites; Lipids
MeSH headings : Histocytological Preparation Techniques / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR:
A robust IR-MALDESI imaging source has been developed, where a tunable mid-IR laser is synchronized with a computer controlled XY translational stage and a high resolving power mass spectrometer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
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