Works (32)

Updated: August 3rd, 2023 21:15

2022 journal article

Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E

VIROLOGY, 571, 21–33.

By: Y. Zhu n, F. Scholle n, S. Kisthardt n & D. Xie n

author keywords: (+)-dihydrokaempferol; <p>(+)-dihydroquercetin (taxifolin)</p>; (+)-dihydromyricetin; Kaempferol; Quercetin; Myricentin; Isoquercitrin; Rutin; Flavan-3-ols
MeSH headings : COVID-19; Coronavirus 229E, Human / drug effects; Coronavirus 229E, Human / physiology; Coronavirus 3C Proteases / antagonists & inhibitors; Flavonols / pharmacology; Humans; Molecular Docking Simulation; SARS-CoV-2 / drug effects; Virus Replication / drug effects
Sources: Web Of Science, ORCID
Added: May 23, 2022

2022 article

A standardized procedure for quantitative evaluation of residual viral activity on antiviral treated textiles

Wang, Z., Amanah, A. Y., Ali, K. M., Payne, L. C., Kisthardt, S., Scholle, F., … Gluck, J. M. (2022, November 2). TEXTILE RESEARCH JOURNAL, Vol. 11.

By: Z. Wang n, A. Amanah n, K. Ali n, L. Payne n, S. Kisthardt n, F. Scholle n, R. Ormond n, K. Mathur n, J. Gluck n

author keywords: SARS-CoV-2; antiviral textiles; Tissue Culture Infectious Dose 50
Sources: Web Of Science, ORCID
Added: November 3, 2022

2022 journal article

Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins

BIOORGANIC CHEMISTRY, 120.

By: M. Mottin*, L. Caesar*, D. Brodsky n, N. Mesquita*, K. Oliveira*, G. Noske n, B. Sousa*, P. Ramos* ...

author keywords: Angelica keiskei; Ashitaba; Chalcones; Zika virus; Polymerase; Protease
MeSH headings : Angelica / chemistry; Animals; Chalcone / pharmacology; Chalcones / chemistry; Chalcones / pharmacology; Chlorocebus aethiops; Humans; RNA; RNA-Dependent RNA Polymerase; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection
Source: Web Of Science
Added: July 18, 2022

2022 journal article

Effect of BIO-PLYTM, a Platelet-Rich Plasma Derived Biologic on PRRSV-2-Infected Macrophages

Viruses, 14(12), 2666.

author keywords: antivirals; biologic; porcine macrophages; PRRSV
MeSH headings : Humans; Swine; Animals; Horses; Porcine respiratory and reproductive syndrome virus; Porcine Reproductive and Respiratory Syndrome / prevention & control; Macrophages; Biological Products
Sources: Web Of Science, ORCID, Crossref
Added: November 29, 2022

2022 article

On-demand, remote and lossless manipulation of biofluid droplets

Wang, W., Sun, J., Vallabhuneni, S., Pawlowski, B., Vahabi, H., Nellenbach, K., … Kota, A. K. (2022, September 7). MATERIALS HORIZONS.

By: W. Wang n, J. Sun*, S. Vallabhuneni n, B. Pawlowski*, H. Vahabi*, K. Nellenbach n, A. Brown n, F. Scholle n, J. Zhao*, A. Kota n

MeSH headings : Humans; Pandemics / prevention & control; Saliva; Disease Outbreaks; Point-of-Care Systems; Health Personnel
Source: Web Of Science
Added: September 19, 2022

2022 journal article

Vandetanib Blocks the Cytokine Storm in SARS-CoV-2-Infected Mice

ACS OMEGA, 7(36), 31935–31944.

Source: Web Of Science
Added: January 3, 2023

2021 journal article

A Liquid Metal Mediated Metallic Coating for Antimicrobial and Antiviral Fabrics

Advanced Materials, 33(45), 2104298.

By: K. Kwon n, S. Cheeseman*, A. Frias‐De‐Diego n, H. Hong*, J. Yang n, W. Jung*, H. Yin*, B. Murdoch* ...

author keywords: antimicrobial; antiviral; galvanic replacement; liquid metal fabric coating
MeSH headings : Alloys / chemistry; Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacology; Antiviral Agents / chemistry; Antiviral Agents / pharmacology; Bacteria / drug effects; Coated Materials, Biocompatible / chemistry; Coated Materials, Biocompatible / pharmacology; Copper / chemistry; Fungi / drug effects; Gallium / chemistry; Textiles / analysis; Viruses / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: September 28, 2021

2021 journal article

Rapid and Repetitive Inactivation of SARS-CoV-2 and Human Coronavirus on Self-Disinfecting Anionic Polymers

ADVANCED SCIENCE, 8(11).

By: B. Peddinti n, S. Downs*, J. Yan n, S. Smith*, R. Ghiladi n, V. Mhetar*, R. Tocchetto*, A. Griffiths*, F. Scholle n, R. Spontak n

author keywords: antiviral materials; charged block polymers; microphase&#8208; ordered materials; polyanions; thermoplastic elastomers
MeSH headings : COVID-19 / prevention & control; COVID-19 / transmission; COVID-19 / virology; Disinfectants / therapeutic use; Humans; Pandemics; Polymers / chemistry; Polymers / therapeutic use; SARS-CoV-2 / drug effects; SARS-CoV-2 / pathogenicity
Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 journal article

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

ACS OMEGA, 6(11), 7454–7468.

By: A. Puhl*, E. Fritch*, T. Lane*, L. Tse*, B. Yount*, C. Sacramento*, N. Fintelman-Rodrigues*, T. Tavella* ...

Source: Web Of Science
Added: June 10, 2021

2021 journal article

Toward Universal Photodynamic Coatings for Infection Control

FRONTIERS IN MEDICINE, 8.

By: C. Ghareeb n, B. Peddinti n, S. Kisthardt n, F. Scholle n, R. Spontak n & R. Ghiladi n

author keywords: antimicrobial; Coronavirus; coatings; photodynamic inactivation; photosensitizer; polymer; singlet oxygen; Staphylococcus aureus
Sources: Web Of Science, ORCID
Added: August 23, 2021

2020 journal article

Photodynamic Coatings on Polymer Microfibers for Pathogen Inactivation: Effects of Application Method and Composition

ACS Applied Materials & Interfaces, 13(1), 155–163.

By: B. Peddinti n, N. Morales-Gagnon n, B. Pourdeyhimi n, F. Scholle n, R. Spontak n & R. Ghiladi n

author keywords: hospital-acquired infections; photodynamic coatings; porphyrin photosensitizer; SARS-CoV-2 virus; polymer microfibers
MeSH headings : COVID-19 / prevention & control; COVID-19 / virology; Escherichia coli / drug effects; Escherichia coli / pathogenicity; Humans; Iatrogenic Disease / prevention & control; Light; Methicillin-Resistant Staphylococcus aureus / drug effects; Methicillin-Resistant Staphylococcus aureus / pathogenicity; Microfibrils / chemistry; Pandemics; Photosensitizing Agents / chemistry; Photosensitizing Agents / pharmacology; Polymers / chemistry; Polymers / pharmacology; Porphyrins / chemistry; Porphyrins / pharmacology; SARS-CoV-2 / drug effects; SARS-CoV-2 / pathogenicity; Singlet Oxygen
Sources: Web Of Science, Crossref, ORCID
Added: January 31, 2021

2019 journal article

A facile strategy for photoactive nanocellulose-based antimicrobial materials

Green Chemistry, 21(12), 3424–3435.

By: D. Alvarado n, D. Argyropoulos n, F. Scholle n, B. Peddinti n & R. Ghiladi n

Sources: Web Of Science, ORCID, Crossref
Added: July 8, 2019

2019 journal article

BODIPY-embedded electrospun materials in antimicrobial photodynamic inactivation

Photochemical & Photobiological Sciences, 18(8), 1923–1932.

By: K. Stoll n, F. Scholle n, J. Zhu n, X. Zhang n & R. Ghiladi n

MeSH headings : Acinetobacter baumannii / drug effects; Acrylic Resins / chemistry; Acrylic Resins / pharmacology; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Boron Compounds / chemistry; Boron Compounds / pharmacology; Klebsiella pneumoniae / drug effects; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Nanofibers / chemistry; Nylons / chemistry; Nylons / pharmacology; Particle Size; Photochemotherapy; Photosensitizing Agents / chemistry; Photosensitizing Agents / pharmacology; Vancomycin-Resistant Enterococci / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: September 16, 2019

2019 journal article

Inherently self-sterilizing charged multiblock polymers that kill drug-resistant microbes in minutes

Materials Horizons, 6(10), 2056–2062.

By: B. Peddinti n, F. Scholle n, M. Vargas n, S. Smith*, R. Ghiladi n & R. Spontak n

Sources: Web Of Science, ORCID, Crossref
Added: December 16, 2019

2018 journal article

Photodynamic Polymers as Comprehensive Anti-Infective Materials: Staying Ahead of a Growing Global Threat

ACS Applied Materials & Interfaces, 10(31), 25955–25959.

By: B. Peddinti n, F. Scholle n, R. Ghiladi n & R. Spontak n

author keywords: antimicrobial photodynamic inactivation; antibacterial surface; anti-infective polymer; antibiotic-resistant bacteria; antiviral; block copolymer; olefin thermoplastic elastomer
MeSH headings : Anti-Infective Agents / chemistry; Light; Photosensitizing Agents; Polymers; Singlet Oxygen
Sources: Crossref, ORCID
Added: February 5, 2020

2016 journal article

Dengue virus NS1 enhances viral replication and pro-inflammatory cytokine production in human dendritic cells

VIROLOGY, 496, 227–236.

By: F. Alayli n & F. Scholle n

author keywords: Dengue; NS1; Nonstructural protein NS1; Dendritic cells; Proinflammatory cytokines; Immune modulation
MeSH headings : Cells, Cultured; Cytokines / biosynthesis; Dendritic Cells / immunology; Dendritic Cells / metabolism; Dendritic Cells / virology; Dengue / immunology; Dengue / metabolism; Dengue / virology; Dengue Virus / classification; Dengue Virus / physiology; Humans; Immunomodulation; Inflammation Mediators / metabolism; Serogroup; Viral Nonstructural Proteins / metabolism; Virus Replication
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Photosensitizer-Embedded Polyacrylonitrile Nanofibers as Antimicrobial Non-Woven Textile

Nanomaterials, 6(4), 77.

By: S. Stanley n, F. Scholle n, J. Zhu n, Y. Lu n, X. Zhang n, X. Situ n, R. Ghiladi n

author keywords: photodynamic inactivation; singlet oxygen; antibacterial; antiviral; photobiocidal; polyacrylonitrile; photosensitizer; porphyrin
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

The adaptor molecule Trif contributes to murine host defense during Leptospiral infection

IMMUNOBIOLOGY, 221(9), 964–974.

By: P. Jayaraman n, A. Devlin n, J. Miller n & F. Scholle n

author keywords: Leptospira interrogans; Leptospirosis; Innate immunity; TRIF
MeSH headings : Adaptor Proteins, Vesicular Transport / genetics; Adaptor Proteins, Vesicular Transport / immunology; Animals; Cytokines / blood; Cytokines / genetics; Cytokines / immunology; Immunoglobulin A / immunology; Immunoglobulin M / immunology; Kidney / immunology; Leptospira / immunology; Leptospirosis / immunology; Lung / immunology; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger / metabolism
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Antiviral, antifungal and antibacterial activities of a BODIPY-based photosensitizer

Molecules, 20(6), 10604–10621.

By: B. Carpenter, X. Situ, F. Scholle, J. Bartelmess, W. Weare & R. Ghiladi

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1 beta Secretion: A Primary Human Monocyte Model

PLOS ONE, 10(8).

By: J. Callaway*, S. Smith*, D. Widman*, K. McKinnon*, F. Scholle n, G. Sempowski, D. Dittmer*, J. Crowe*, A. Silva*, J. Ting*

MeSH headings : Animals; Antibodies, Neutralizing / administration & dosage; Antibodies, Viral / administration & dosage; Antibodies, Viral / immunology; Chlorocebus aethiops; Dengue Virus / immunology; Dengue Virus / pathogenicity; Humans; Interleukin-1beta / immunology; Interleukin-1beta / metabolism; Monocytes / immunology; Monocytes / virology; Severe Dengue / immunology; Severe Dengue / virology; Vero Cells; Virus Replication / immunology
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Synthesis, Characterization, and Antimicrobial Efficacy of Photomicrobicidal Cellulose Paper

BIOMACROMOLECULES, 16(8), 2482–2492.

MeSH headings : Anti-Infective Agents / administration & dosage; Anti-Infective Agents / chemical synthesis; Anti-Infective Agents / chemistry; Cellulose / administration & dosage; Cellulose / chemical synthesis; Cellulose / chemistry; Enterococcus faecium / drug effects; Humans; Klebsiella pneumoniae / drug effects; Light; Microbial Sensitivity Tests; Paper; Photosensitizing Agents / chemical synthesis; Photosensitizing Agents / chemistry; Porphyrins / administration & dosage; Porphyrins / chemical synthesis; Porphyrins / chemistry; Pseudomonas aeruginosa / drug effects; Staphylococcus aureus / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Abrogation of TLR3 inhibition by discrete amino acid changes in the C-terminal half of the West Nile virus NS1 protein

VIROLOGY, 456, 96–107.

By: C. Morrison n & F. Scholle n

author keywords: Flavivirus; West Nile virus; TLR3; NS1; Innate immunity
MeSH headings : Amino Acid Substitution; DNA Mutational Analysis; HeLa Cells; Host-Pathogen Interactions; Humans; Immune Evasion; Mutant Proteins / genetics; Mutant Proteins / immunology; Toll-Like Receptor 3 / antagonists & inhibitors; Toll-Like Receptor 3 / immunology; Viral Nonstructural Proteins / genetics; Viral Nonstructural Proteins / immunology; Virus Replication; West Nile virus / genetics; West Nile virus / immunology; West Nile virus / physiology
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Modulation of innate immune signaling by the secreted form of the West Nile virus NS1 glycoprotein

VIROLOGY, 458, 172–182.

By: K. Crook n, M. Miller-Kittrell n, C. Morrison n & F. Scholle n

author keywords: West Nile virus; Flaviviridae; Nonstructural protein; Toll like receptor; Innate immunity
MeSH headings : Animals; HeLa Cells; Humans; Immunity, Innate; Luciferases / metabolism; Macrophages / immunology; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Myeloid Cells / immunology; Myeloid Cells / metabolism; Poly I-C / pharmacology; Signal Transduction / immunology; Specific Pathogen-Free Organisms; Toll-Like Receptor 3 / antagonists & inhibitors; Viral Nonstructural Proteins / immunology; Viral Nonstructural Proteins / physiology; West Nile virus / immunology; West Nile virus / metabolism
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Replication of Many Human Viruses Is Refractory to Inhibition by Endogenous Cellular MicroRNAs

JOURNAL OF VIROLOGY, 88(14), 8065–8076.

By: H. Bogerd*, R. Skalsky*, E. Kennedy*, Y. Furuse*, A. Whisnant*, O. Flores*, K. Schultz*, N. Putnam* ...

MeSH headings : Animals; Cell Line; Gene Silencing; Host-Pathogen Interactions; Humans; Immune Evasion; MicroRNAs / genetics; MicroRNAs / immunology; Virus Replication; Viruses / genetics; Viruses / growth & development; Viruses / immunology
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling

VACCINE, 30(8), 1465–1475.

By: E. Winkelmann, D. Widman*, J. Xia*, T. Ishikawa*, M. Miller-Kittrell n, M. Nelson*, N. Bourne*, F. Scholle n, P. Mason*, G. Milligan*

author keywords: West Nile virus; Single-cycle virus; CD8(+) T cell; Type I IFN
MeSH headings : Adjuvants, Immunologic / pharmacology; Animals; Antibodies, Viral / blood; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Immunoglobulin G / blood; Lymph Nodes / immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Interferon alpha-beta / deficiency; Receptor, Interferon alpha-beta / immunology; Signal Transduction; West Nile Fever / immunology; West Nile Fever / prevention & control; West Nile Virus Vaccines / immunology
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus

BMC GENOMICS, 11.

By: R. Skalsky*, D. Vanlandingham*, F. Scholle n, S. Higgs* & B. Cullen*

MeSH headings : Aedes / genetics; Aedes / virology; Animals; Cell Line; Computational Biology; Culex / genetics; Culex / virology; Female; Insect Vectors / genetics; MicroRNAs / genetics; Sequence Analysis, RNA; West Nile virus
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-kappa B-dependent transcription of TNF-alpha and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

JOURNAL OF INFLAMMATION-LONDON, 7.

By: A. Oyegunwa n, M. Sikes n, J. Wilson n, F. Scholle n & S. Laster n

Source: Web Of Science
Added: August 6, 2018

2009 journal article

Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines

JOURNAL OF INFLAMMATION-LONDON, 6.

By: D. Eads n, R. Hansen n, A. Oyegunwa n, C. Cecil n, C. Culver n, F. Scholle n, I. Petty n, S. Laster n

Source: Web Of Science
Added: August 6, 2018

2008 journal article

West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction

JOURNAL OF VIROLOGY, 82(17), 8262–8271.

By: J. Wilson n, P. Sessions n, M. Leon n & F. Scholle n

MeSH headings : Animals; Chlorocebus aethiops; Genes, Reporter; HeLa Cells; Humans; Immunity, Innate; Immunohistochemistry; Luciferases / metabolism; Plasmids; Replicon; Signal Transduction / immunology; Signal Transduction / physiology; Toll-Like Receptor 3 / antagonists & inhibitors; Vero Cells; Viral Nonstructural Proteins / physiology; Viral Plaque Assay; West Nile virus / immunology; West Nile virus / physiology
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Early production of type I interferon during West Nile virus infection: Role for lymphoid tissues in IRF3-independent interferon production

Journal of Virology, 81(17), 9100–9108.

By: N. Bourne*, F. Scholle n, M. Silva, S. Rossi, N. Dewsbury, B. Judy*, J. De Aguiar*, M. Leon n ...

MeSH headings : Animals; Antigens, Viral / analysis; Disease Models, Animal; Gene Expression; Interferon Regulatory Factor-3 / genetics; Interferon Regulatory Factor-3 / immunology; Interferon Type I / biosynthesis; Interferon Type I / blood; Interferon Type I / immunology; Lymph Nodes / virology; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger / biosynthesis; West Nile Fever / immunology; West Nile virus / immunology
Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Evaluation of replicative capacity and genetic stability of West Nile virus replicons using highly efficient packaging cell lines

Virology, 351(1), 196–209.

By: R. Fayzulin*, F. Scholle*, O. Petrakova*, I. Frolov* & P. Mason

author keywords: flavivirus; replicon; packaging; virus-like particle; noncytopathic replicon
MeSH headings : Animals; Chlorocebus aethiops; Cricetinae; Genetic Variation; Vero Cells; Virus Assembly; Virus Replication / physiology; West Nile virus / genetics; West Nile virus / physiology
Source: Crossref
Added: February 24, 2020

2005 journal article

West Nile virus replication interferes with both poly(I:C)-induced interferon gene transcription and response to interferon treatment

Virology, 342(1), 77–87.

By: F. Scholle* & P. Mason*

author keywords: West Nile virus; interferon; TLR3; IRF3; innate immunity; double-stranded RNA
MeSH headings : Active Transport, Cell Nucleus; Cell Line; Dimerization; HeLa Cells; Humans; Immunity, Innate; Interferon Regulatory Factor-3 / chemistry; Interferon Regulatory Factor-3 / metabolism; Interferon-beta / biosynthesis; Interferon-beta / genetics; Poly I-C / pharmacology; RNA, Viral / genetics; Replicon; STAT1 Transcription Factor / metabolism; Signal Transduction; Transcription, Genetic / drug effects; Virus Replication; West Nile virus / genetics; West Nile virus / immunology; West Nile virus / pathogenicity; West Nile virus / physiology
Source: Crossref
Added: February 24, 2020