Works Published in 2017
Displaying works 121 - 140 of 248 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program
Nature Communications, 8(1).
MeSH headings : Acetylation; Animals; DNA-Binding Proteins / metabolism; Heat Shock Transcription Factors / genetics; Heat Shock Transcription Factors / metabolism; Humans; Mice; Molecular Chaperones; Muscle, Skeletal / metabolism; Protein Processing, Post-Translational; Protein Refolding; TDP-43 Proteinopathies / metabolism
TL;DR:
It is shown that acetylation of the protein triggers TDP-43 pathology in cultured cells and mouse skeletal muscle, which can be cleared through an HSF1-dependent chaperone mechanism that disaggregates the protein.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: August 6, 2018
2017 journal article
The virtual approach to the assessment of skeletal injuries in human skeletal remains of forensic importance
JOURNAL OF FORENSIC AND LEGAL MEDICINE, 49, 59–75.
author keywords: Perimortem skeletal injuries; Reassembly; Virtual approach; 3D printing
MeSH headings : Adult; Computer Simulation; Foot Bones / injuries; Foot Bones / pathology; Forensic Anthropology / methods; Fractures, Bone / pathology; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Male; Middle Aged; Printing, Three-Dimensional; Skull Fractures / pathology; Wounds, Gunshot / pathology; Wounds, Penetrating / pathology
TL;DR:
The present study employs a 3D virtual approach to assess mechanisms of skeletal injuries, and provides an expert opinion of causative tools in three forensic cases involving human skeletal remains where integrity was compromised by multiple peri- or postmortem alterations resulting in fragmentation and/or incompleteness
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
The neuropeptide corazonin controls social behavior and caste identity in ants
Cell, 170(4), 748-.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Structural studies of Neurospora crassa LPMO9D and redox partner CDHIIA using neutron crystallography and small-angle scattering
CARBOHYDRATE RESEARCH, 448, 200–204.
author keywords: Polysaccharide monooxygenases; Cellobiose dehydrogenases; Neutron diffraction; Neutron scattering; X-ray induced photoreduction
MeSH headings : Carbohydrate Dehydrogenases / chemistry; Carbohydrate Dehydrogenases / metabolism; Catalytic Domain; Crystallography, X-Ray; Mixed Function Oxygenases / chemistry; Mixed Function Oxygenases / metabolism; Models, Molecular; Neurospora crassa / enzymology; Oxidation-Reduction; Scattering, Small Angle
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
7. Affordable and Clean Energy
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes
PARTICLE AND FIBRE TOXICOLOGY, 14.
author keywords: Carbon nanotubes; Lung; Fibrosis; Growth factors; Transcription factors
MeSH headings : Animals; Bronchoalveolar Lavage Fluid / chemistry; Cell Proliferation / drug effects; Cytokines / metabolism; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Epithelial Cells / pathology; Genetic Predisposition to Disease; Granuloma, Respiratory Tract / chemically induced; Granuloma, Respiratory Tract / metabolism; Granuloma, Respiratory Tract / pathology; Immunoglobulin E / blood; Lung / drug effects; Lung / metabolism; Lung / pathology; Male; Mice, Knockout; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Phenotype; Phosphorylation; Pneumonia / chemically induced; Pneumonia / metabolism; Pneumonia / pathology; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / genetics; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Respiratory Hypersensitivity / chemically induced; Respiratory Hypersensitivity / genetics; Respiratory Hypersensitivity / metabolism; Respiratory Hypersensitivity / pathology; Risk Assessment; STAT1 Transcription Factor / deficiency; STAT1 Transcription Factor / genetics; STAT1 Transcription Factor / metabolism; Signal Transduction / drug effects; Smad2 Protein / metabolism; Smad3 Protein / metabolism; Time Factors; Transforming Growth Factor beta1 / metabolism
TL;DR:
Rigidity plays a key role in the toxicity of MWCNTs and results in increased inflammatory, immunologic, and fibrogenic effects in the lung, and both rigidity and genetic susceptibility should be major considerations for risk assessment of MMWNTs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Revision of the cyprinid genus Crossocheilus (tribe Labeonini) with description of a new species
Copeia, 105(2), 269–292.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Physiological responses to short-term thermal stress in mayfly (Neocloeon triangulifer) larvae in relation to upper thermal limits
JOURNAL OF EXPERIMENTAL BIOLOGY, 220(14), 2598–2605.
author keywords: Temperature; Aerobic scope; Hypoxia; Aquatic insect; Gene expression
MeSH headings : Acclimatization / physiology; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone / pharmacology; Ecosystem; Ephemeroptera / growth & development; Ephemeroptera / physiology; Gene Expression; Hot Temperature / adverse effects; Larva / growth & development; Larva / physiology; Oxygen / physiology; Oxygen Consumption / drug effects; Oxygen Consumption / physiology
TL;DR:
The results suggest that the chronic thermal limits of this species are likely not driven by oxygen limitation, but rather are determined by other factors, e.g. bioenergetics costs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Organic Food in the Diet: Exposure and Health Implications
Annual Review of Public Health, 38(1), 295–313.
author keywords: organic food; organic vegetables; naturalness; compositional differences; health effects
MeSH headings : Agriculture / methods; Diet; Food; Food Contamination / prevention & control; Food, Organic; Humans; Nutritive Value
TL;DR:
This review provides an update on market data and consumer preferences for organic food and summarizes the scientific evidence for compositional differences and health benefits of organic compared with conventionally produced food.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 review
Non-genomic transmission of longevity between generations: potential mechanisms and evidence across species
[Review of ]. EPIGENETICS & CHROMATIN, 10.
author keywords: Epigenetics; DNA methylation; Transgenerational inheritance; Aging; Age-associated disease; Longevity
MeSH headings : Animals; Epigenesis, Genetic; Evolution, Molecular; Gene Expression Regulation, Developmental; Humans; Longevity / genetics
TL;DR:
Findings from animal models, including worms, insects, and rodents, and also from human studies are summarized, indicating that lifespan and longevity-associated characteristics can be transmitted across generations via non-genetic factors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Is Body Mass Index the Best Adiposity Measure for Prostate Cancer Risk? Results From a Veterans Affairs Biopsy Cohort
UROLOGY, 105, 129–135.
MeSH headings : Adiposity; Aged; Body Mass Index; Case-Control Studies; Cohort Studies; Humans; Logistic Models; Male; Middle Aged; Neoplasm Grading; Prostatic Neoplasms / etiology; Prostatic Neoplasms / pathology; Risk Factors; Self Report; Veterans; Waist Circumference
TL;DR:
This study supports the idea that higher adiposity is selectively associated with high-grade PC and reinforces the continued use of self-reported BMI as a measure of obesity in epidemiologic studies of PC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 article
Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 38, Vol. 38, pp. 279–294.
author keywords: exposures; bioinformatics; genomics; environment-wide association studies; data standards
MeSH headings : Biomedical Research; Computational Biology; Ecosystem; Environmental Exposure / adverse effects; Humans; Public Health; Risk Factors
TL;DR:
If an exposome data ecosystem is brought to fruition, it will likely play a role as central as genomic science has had in molding the current and new generations of biomedical researchers, computational scientists, and public health research programs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 journal article
Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism
TOXICOLOGICAL SCIENCES, 158(1), 48–62.
author keywords: population; trichloroethylene; mouse
MeSH headings : Alcohol Dehydrogenase / biosynthesis; Aldehyde Dehydrogenase / biosynthesis; Animals; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene-Environment Interaction; Kidney / drug effects; Liver / drug effects; Liver / enzymology; Liver / metabolism; Male; Mice; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors / genetics; Peroxisome Proliferator-Activated Receptors / metabolism; Quantitative Trait Loci; Species Specificity; Toxicokinetics; Trichloroethylene / blood; Trichloroethylene / pharmacokinetics; Trichloroethylene / toxicity
TL;DR:
This study shows that CC mouse population is a valuable tool to quantitatively evaluate inter-individual variability in chemical metabolism and to identify genes and pathways that may underpin population differences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Assessing the Potential for Bias From Nonresponse to a Study Follow-up Interview: An Example From the Agricultural Health Study
American Journal of Epidemiology, 186(4), 395–404.
author keywords: attrition; epidemiologic methods; inverse probability weights; loss to follow-up; occupational/environmental epidemiology; prospective studies; selection bias
MeSH headings : Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / prevention & control; Bias; Cause of Death; Epidemiologic Research Design; Farmers / statistics & numerical data; Female; Follow-Up Studies; Humans; Interviews as Topic; Iowa / epidemiology; Lost to Follow-Up; Male; Middle Aged; Neoplasms / epidemiology; North Carolina; Odds Ratio; Prospective Studies; Smoking / epidemiology
TL;DR:
This example provides a demonstration of investigating the influence of attrition in cohort studies using information that has been self-reported after enrollment, and the ability of inverse probability weighting (IPW) to reduce bias.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Assessing the Exposome with External Measures: Commentary on the State of the Science and Research Recommendations
Annual Review of Public Health, 38(1), 215–239.
author keywords: exposome; external exposures; geographic information systems; remote sensing; global positioning systems; smartphones
MeSH headings : Environmental Exposure / adverse effects; Epigenomics; Geographic Information Systems; Health Behavior; Humans; Life Style; Research
TL;DR:
Major scientific and technological advances that inform external assessment of the exposome are described, including geographic information systems; remote sensing; global positioning system and geolocation technologies; portable and personal sensing; and self-reported questionnaire assessments, which increasingly rely on Internet-based platforms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
A procedure to detect general association based on concentration of ranks
Stat, 6(1), 88–101.
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
The evolution of cuticular fertility signals in eusocial insects
CURRENT OPINION IN INSECT SCIENCE, 22, 79–84.
MeSH headings : Animal Communication; Animals; Biological Evolution; Fertility / physiology; Hymenoptera / physiology; Isoptera / physiology; Pheromones / metabolism; Social Behavior
TL;DR:
This review synthesizes conflicting studies into an evolutionary framework suggesting a transition of reproductive communication from cue-like signature mixtures, to learned fertility signals, to innate queen pheromones that evolved across eusocial insects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Sulfate transport kinetics and toxicity are modulated by sodium in aquatic insects
AQUATIC TOXICOLOGY, 190, 62–69.
author keywords: Aquatic insects; Major ions; Physiology; Osmoregulation; Toxicity; Sulfate
MeSH headings : Animals; Aquatic Organisms / drug effects; Aquatic Organisms / metabolism; Ecosystem; Fresh Water / chemistry; Insecta / drug effects; Insecta / metabolism; Ion Transport / drug effects; Kinetics; Salinity; Sodium / analysis; Sodium / pharmacology; Sulfates / metabolism; Sulfates / toxicity; Water Pollutants, Chemical / metabolism; Water Pollutants, Chemical / toxicity
TL;DR:
The combination of elevated sulfate and low sodium commonly observed in streams affected by mountaintop coal mining has the potential to cause toxicity in sensitive aquatic insects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Stable Transmission of Borrelia burgdorferi Sensu Stricto on the Outer Banks of North Carolina
ZOONOSES AND PUBLIC HEALTH, 64(5), 337–354.
author keywords: Borrelia burgdorferi; Ixodes scapularis; Peromyscus leucopus; Oryzomys palustris; Sylvilagus palustris; Outer Banks; North Carolina
MeSH headings : Animals; Bacteriological Techniques; Borrelia burgdorferi / genetics; Borrelia burgdorferi / isolation & purification; DNA, Bacterial / genetics; Female; Ixodes / microbiology; Lyme Disease / epidemiology; Lyme Disease / microbiology; Lyme Disease / transmission; Lyme Disease / veterinary; Male; North Carolina / epidemiology; Phylogeny; Rabbits / microbiology; Reptiles / microbiology; Rodentia / microbiology
TL;DR:
Two studies indicate that B. burgdorferi sensu stricto is endemic in questing I. scapularis and mammalian tick hosts on the Outer Banks of North Carolina.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 article
Prolonged particulate chromate exposure does not inhibit homologous recombination repair in North Atlantic right whale (Eubalaena glacialis) lung cells
Browning, C. L., Wise, C. F., & Wise, J. P., Sr. (2017, September 15). TOXICOLOGY AND APPLIED PHARMACOLOGY, Vol. 331, pp. 18–23.
author keywords: Hexavalent chromium; Homologous recombination repair; Genomic instability; North Atlantic right whale lung fibroblasts; Rad51
MeSH headings : Animals; Cell Survival / drug effects; Cell Survival / physiology; Cells, Cultured; Chromates / administration & dosage; Chromates / toxicity; Dose-Response Relationship, Drug; Lung / cytology; Lung / drug effects; Lung / physiology; Particulate Matter / administration & dosage; Particulate Matter / toxicity; Recombinational DNA Repair / drug effects; Recombinational DNA Repair / physiology; Respiratory Mucosa / drug effects; Respiratory Mucosa / physiology; Time Factors; Whales; Zinc Compounds / administration & dosage; Zinc Compounds / toxicity
TL;DR:
Results suggest prolonged Cr(VI) exposure affects HR repair and genomic stability differently in whale and human lung cells, and future investigation of the differences in how human and whale cells respond to chemical carcinogens may provide valuable insight into mechanisms of preventing chemical carcinogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Preliminary evidence for snail deformation from a Eutrophic lake
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 53, 219–226.
author keywords: Eutrophication; Snail; Deformity; Transcriptomic; Mechanism
MeSH headings : Animals; China; Chlorophyll / analysis; Chlorophyll A; Congenital Abnormalities; Eutrophication; Female; Gene Expression Profiling; Lakes / chemistry; Snails / anatomy & histology; Snails / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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