Works Published in 2017
Displaying works 121 - 140 of 210 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Pig as a biomedical model: Putting the porcine lung dendritic cells/macrophages network into light
Revue Des Maladies Respiratoires, 34, A328.
Source: ORCID
Added: February 11, 2019
2017 conference paper
Integrative and differential analysis of transcriptomes and chromatin accessibility regions reveals regulatory mechanisms involved in pig immune and metabolic functions
36th International Society for Animal Genetics Conference, np.
Source: ORCID
Added: February 11, 2019
2017 journal article
HIV/Human herpesvirus co-infections: Impact on tryptophan-kynurenine pathway and immune reconstitution
PLOS ONE, 12(10), e0186000.
Ed(s): O. Sued
MeSH headings : Adult; Antibodies, Viral / blood; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes / immunology; Coinfection / blood; Coinfection / epidemiology; Coinfection / immunology; Coinfection / virology; Female; HIV Infections / blood; HIV Infections / epidemiology; HIV Infections / immunology; HIV Infections / virology; Herpes Simplex / blood; Herpes Simplex / epidemiology; Herpes Simplex / immunology; Herpes Simplex / virology; Herpesvirus 1, Human / isolation & purification; Herpesvirus 1, Human / pathogenicity; Humans; Immune Reconstitution Inflammatory Syndrome / blood; Immune Reconstitution Inflammatory Syndrome / immunology; Immune Reconstitution Inflammatory Syndrome / metabolism; Immune Reconstitution Inflammatory Syndrome / virology; Inflammation / blood; Inflammation / epidemiology; Inflammation / immunology; Inflammation / virology; Kynurenine / metabolism; Male; Metabolic Networks and Pathways; Seroepidemiologic Studies; Tryptophan / metabolism
TL;DR:
Multiple HHV co-infections are common among ART-treated HIV-infected participants in the developing country setting and associated with persistent immune activation and poorer CD4 T-cell recovery.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 11, 2019
2017 journal article
Chlamydia suis and Chlamydia trachomatis induce multifunctional CD4 T cells in pigs
Vaccine, 35(1), 91–100.
Contributors: T. Käser n, J. Pasternak *, M. Delgado-Ortega*, G. Hamonic*, K. Lai *, J. Erickson *, S. Walker*, J. Dillon *, V. Gerdts *, F. Meurens *
author keywords: Chlamydia suis; Chlamydia trachomatis; Animal model; Swine; Vaccine development; One Health
MeSH headings : Administration, Intravaginal; Animals; Antibodies, Bacterial / blood; Antibody Formation; CD4-Positive T-Lymphocytes / immunology; Chlamydia / immunology; Chlamydia / pathogenicity; Chlamydia Infections / immunology; Chlamydia Infections / microbiology; Chlamydia Infections / pathology; Chlamydia Infections / veterinary; Cytokines / metabolism; Host-Pathogen Interactions; Immunity, Cellular; Immunity, Humoral; Swine; Time Factors
TL;DR:
The T-cell-mediated immune responses were triggered by both homologous or heterologous re-stimulation indicating that cross-protection between the two chlamydia species is possible and could bridge the gap to the clinical phase for C. trachomatis vaccine research.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: February 11, 2019
2017 journal article
MeSH headings : Biomedical Research; Health Resources; Humans; Influenza Vaccines; Influenza, Human; Pandemics
Source: ORCID
Added: February 11, 2019
2017 journal article
Response of House Finches Recovered from Mycoplasma gallisepticum to Reinfection with a Heterologous Strain
AVIAN DISEASES, 61(4), 437–441.
author keywords: virulence; emerging disease
MeSH headings : Animals; Bird Diseases / microbiology; Finches; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Mycoplasma gallisepticum / genetics; Mycoplasma gallisepticum / physiology; New York; Recurrence
TL;DR:
The data suggest that the observed increase in Mycoplasma gallisepticum virulence, once the disease has become endemic in free-ranging house finches is—in part—driven by increased resistance of recovered birds to strains of equal or lower virulence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Effect of intra-articular administration of superparamagnetic iron oxide nanoparticles (SPIONs) for MRI assessment of the cartilage barrier in a large animal model
PLOS ONE, 12(12).
MeSH headings : Animals; Biomarkers / metabolism; Cartilage, Articular / diagnostic imaging; Cartilage, Articular / metabolism; Chemotaxis, Leukocyte; Coculture Techniques; Drug Administration Routes; Female; Fluorescent Dyes; Horses; Joints; Magnetic Resonance Imaging / methods; Magnetite Nanoparticles / administration & dosage; Male; Microscopy, Confocal; Models, Animal; Neutrophils / cytology; Swine
TL;DR:
Results demonstrate an increase in MRI signal following conditioning of porcine joints which suggests that nanoparticle dependent compositional cartilage imaging is feasible, and could potentially lead to a new diagnostic technique for early detection of cartilage disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Bibliometric Network Analysis and Visualization for Serials Librarians: An Introduction to Sci2
SERIALS REVIEW, 43(3-4), 239–245.
author keywords: bibliometric analysis; citation networks; network analysis
TL;DR:
Methods of using data from citation databases to generate bibliometric analyses of journal titles, subject matter, and coauthorship networks using the open software tool Sci2 can be used to enhance responsive institutional and network collecting and to connect users to additional research and publication partners.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
The Effects of an Environmentally Relevant Level of Arsenic on the Gut Microbiome and Its Functional Metagenome
TOXICOLOGICAL SCIENCES, 160(2), 193–204.
author keywords: arsenic; gut microbiome; metagenomics; functional pathways
MeSH headings : Animals; Arsenites / toxicity; Bacteria / classification; Bacteria / drug effects; Bacteria / genetics; Dysbiosis; Environmental Pollutants / toxicity; Female; Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / genetics; Gene Expression Regulation, Bacterial; Intestines / drug effects; Intestines / microbiology; Metagenome / drug effects; Metagenome / genetics; Mice, Inbred C57BL; Ribotyping; Sodium Compounds / toxicity; Time Factors
TL;DR:
It is demonstrated that arsenic exposure, at an environmentally relevant dose, not only perturbed the communal composition of the gut microbiome but also profoundly altered a variety of important bacterial functional pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Pharmacokinetics and toxicity of subcutaneous administration of carboplatin in poloxamer 407 in a rodent model pilot study
PLoS One, 12(10).
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Creation and Evaluation of New Porcine Model for Investigation of Treatments of Surgical Site Infection
TISSUE ENGINEERING PART C-METHODS, 23(11), 795–803.
author keywords: surgical site infection; porcine model; antimicrobial scaffold; silver; electrospinning; MRSA
MeSH headings : Animals; Anti-Infective Agents / pharmacology; Anti-Infective Agents / therapeutic use; Disease Models, Animal; Female; Methicillin-Resistant Staphylococcus aureus / drug effects; Nanofibers / chemistry; Nanofibers / ultrastructure; Polyesters / chemistry; Porosity; Surgical Wound Infection / drug therapy; Surgical Wound Infection / microbiology; Surgical Wound Infection / pathology; Sus scrofa; Tissue Scaffolds / chemistry
TL;DR:
A porcine full-thickness incision model to investigate SSI caused by methicillin-resistant Staphylococcus aureus is developed, and the potential of silver releasing nanofibrous scaffolds for treatment/prevention of SSI is confirmed, and a new porcines model is introduced for in vivo evaluation of additional SSI treatment approaches are introduced.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 article
Pathology in Practice
Meichner, K., Li, C.-F., Harrell, K., Neel, J. A., & Tarigo, J. L. (2017, October 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 251, pp. 793–796.
Contributors: K. Meichner*, C. Li, K. Harrell, J. Neel* & J. Tarigo
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bile / chemistry; Bile / microbiology; Cat Diseases / blood; Cat Diseases / microbiology; Cat Diseases / pathology; Cats; Cholangitis / complications; Cholangitis / drug therapy; Cholangitis / pathology; Cholangitis / veterinary; Diagnosis, Differential; Female; Gram-Negative Bacterial Infections / complications; Gram-Negative Bacterial Infections / drug therapy; Gram-Negative Bacterial Infections / pathology; Gram-Negative Bacterial Infections / veterinary; Sphingomonas / isolation & purification; Vomiting / etiology; Vomiting / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Optimal control of vaccination rate in an epidemiological model of Clostridium difficile transmission
JOURNAL OF MATHEMATICAL BIOLOGY, 75(6-7), 1693–1713.
author keywords: Optimal control; Clostridium difficile; Vaccination; Ordinary differential equations; Healthcare setting
MeSH headings : Bacterial Vaccines / pharmacology; Clostridioides difficile; Computer Simulation; Cross Infection / epidemiology; Cross Infection / prevention & control; Cross Infection / transmission; Disease Susceptibility; Enterocolitis, Pseudomembranous / epidemiology; Enterocolitis, Pseudomembranous / prevention & control; Enterocolitis, Pseudomembranous / transmission; Epidemics / prevention & control; Epidemics / statistics & numerical data; Humans; Mathematical Concepts; Models, Biological; Time Factors; Vaccination / methods; Vaccination / statistics & numerical data
TL;DR:
This paper modify and update a compartmental model of nosocomial C. difficile transmission to include vaccination and applies optimal control theory to determine the time-varying optimal vaccination rate that minimizes a combination of disease prevalence and spread in the hospital population as well as cost, in terms of time and money, associated with vaccination.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
Horizontal Dissemination of Antimicrobial Resistance Determinants in Multiple Salmonella Serotypes following Isolation from the Commercial Swine Operation Environment after Manure Application
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 83(20).
author keywords: Salmonella; plasmid; antimicrobial resistance; horizontal gene transfer; environment; environmental microbiology; swine farm
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Conjugation, Genetic; Drug Resistance, Bacterial; Gene Transfer, Horizontal; Integrons; Manure / microbiology; Microbial Sensitivity Tests; Phylogeny; Plasmids / genetics; Plasmids / metabolism; Salmonella Infections, Animal / microbiology; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Salmonella enterica / metabolism; Serogroup; Swine; Swine Diseases / microbiology
TL;DR:
Significant evidence is provided on the importance of horizontal dissemination of resistance determinants through plasmids of multiple Salmonella serotypes distributed across commercial swine farms after manure application and the deposition of manure generated in swine production systems into the environment is identified as a potential source of AMR dissemination.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 review
Elucidating the role of host long non-coding RNA during viral infection: Challenges and paths forward
[Review of ]. Vaccines, 5(4).
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
PREVALENCE OF CYSTINURIA IN SERVALS (LEPTAILURUS SERVAL) IN THE UNITED STATES
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 48(4), 1102–1107.
author keywords: Cyanide-nitroprusside test; cystine; cystinuria; Leptailurus serval; serval; urolithiasis
MeSH headings : Animals; Cystinuria / diagnosis; Cystinuria / epidemiology; Cystinuria / pathology; Cystinuria / veterinary; Data Collection; Felidae; United States / epidemiology
TL;DR:
This condition is likely underreported in servals and should be ruled out in any serval with nonspecific signs of illness; neurologic signs such as lethargy, ataxia, or seizures; ptyalism; or signs of lower urinary tract disease such as dysuria, hematuria, stranguria, pollakiuria, or urethral obstructions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Other viruses: Hepeviridae, hepadnaviridae, deltaviruses, nodaviridae, and unclassified viruses
Fenner's Veterinary Virology, 5th Edition, 547–555.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Early weaning stress induces chronic functional diarrhea, intestinal barrier defects, and increased mast cell activity in a porcine model of early life adversity
NEUROGASTROENTEROLOGY AND MOTILITY, 29(11).
author keywords: developmental origins of health and disease; early life adversity; intestinal permeability; large animal model; mast cell; mast cell plexitis; translational research
MeSH headings : Animals; Cell Count; Colon / pathology; Diarrhea / etiology; Disease Models, Animal; Enteric Nervous System / pathology; Female; Ileum / metabolism; Ileum / pathology; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Intestinal Mucosa / physiopathology; Intestines / pathology; Intestines / physiopathology; Male; Mast Cells / metabolism; Mast Cells / physiology; Stress, Psychological / complications; Sus scrofa; Tryptases / metabolism; Weaning
TL;DR:
Early life adversity is a risk factor for development of gastrointestinal disorders later in life and the underlying mechanisms through which ELA and sex interact to influence disease susceptibility remains poorly understood.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 review
The route of inoculation dictates the replication patterns of the infectious laryngotracheitis virus (ILTV) pathogenic strain and chicken embryo origin (CEO) vaccine
[Review of ]. AVIAN PATHOLOGY, 46(6), 585–593.
author keywords: Infectious laryngotracheitis virus; conjunctiva; trachea; Harderian gland; CEO vaccine
MeSH headings : Animals; Chick Embryo; Chickens / immunology; Chickens / virology; Herpesviridae Infections / prevention & control; Herpesviridae Infections / veterinary; Herpesviridae Infections / virology; Herpesvirus 1, Gallid / immunology; Herpesvirus 1, Gallid / pathogenicity; Herpesvirus 1, Gallid / physiology; Poultry Diseases / prevention & control; Poultry Diseases / virology; Specific Pathogen-Free Organisms; Trachea / virology; Vaccination / veterinary; Viral Load / veterinary; Viral Vaccines / immunology; Virus Replication
TL;DR:
Findings from this study suggest that interactions of the virus with the epithelial-lymphoid tissues of the nasal cavity, conjunctiva and the Harderian gland dictate patterns of ILTV lytic replication.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 journal article
TIM1 (HAVCR1) Is Not Essential for Cellular Entry of Either Quasi-enveloped or Naked Hepatitis A Virions
MBIO, 8(5).
author keywords: hepatitis A virus; hepatovirus; phosphatidylserine; picornavirus; receptor; viral attachment
MeSH headings : Animals; CRISPR-Cas Systems; Carcinoma, Hepatocellular; Cell Line, Tumor; Chlorocebus aethiops; Hepatitis A / virology; Hepatitis A Virus Cellular Receptor 1 / deficiency; Hepatitis A Virus Cellular Receptor 1 / genetics; Hepatitis A Virus Cellular Receptor 1 / metabolism; Hepatitis A virus / metabolism; Hepatitis A virus / pathogenicity; Hepatitis A virus / physiology; Host-Pathogen Interactions; Humans; Liver / pathology; Liver / physiopathology; Liver / virology; Mice; Receptor, Interferon alpha-beta / deficiency; Receptor, Interferon alpha-beta / genetics; Receptor, Interferon alpha-beta / metabolism; Vero Cells; Virion / metabolism; Virion / pathogenicity; Virion / physiology; Virus Attachment; Virus Internalization; Virus Replication
TL;DR:
It is shown here that TIM1 (HAVCR1) is not an essential cellular receptor for HAV entry into cultured cells or required for viral replication and pathogenesis in permissive strains of mice, although it may facilitate early stages of infection by binding phosphatidylserine on the eHAV surface.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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