Works Published in 2006
Displaying works 81 - 100 of 134 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2006 journal article
Mechanisms of mucus secretion in the airways.
404nOtfound, 2, 24–29.
Source: NC State University Libraries
Added: August 6, 2018
2006 article
Regulation of airway mucin secretion by MARCKS protein involves the chaperones heat shock protein 70 and Cysteine string protein.
404nOtfound, Vol. 3, p. 493a.
MeSH headings : Blotting, Western; Bronchi / cytology; Bronchi / metabolism; HSP40 Heat-Shock Proteins / metabolism; HSP70 Heat-Shock Proteins / metabolism; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins / metabolism; Protein Kinase C / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism
Source: NC State University Libraries
Added: August 6, 2018
2006 article
MARCKS related peptide improves airway obstruction related to mucus secretion in a mouse model of asthma.
404nOtfound, Vol. 3, p. A713.
Source: NC State University Libraries
Added: August 6, 2018
2006 patent
Methods for regulating inflammatory mediators and peptides useful therein
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Effects of residual smoothing on the posterior of the fixed effects in disease-mapping models
Biometrics, 62(4), 1197–1206.
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2006 journal article
Direct high-resolution peptide and protein analysis by desorption electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 20(22), 3409–3411.
MeSH headings : Bradykinin / analysis; Formates / analysis; Glucagon / analysis; Insulin / analysis; Melitten / analysis; Peptides / analysis; Proteins / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectroscopy, Fourier Transform Infrared; Vasodilator Agents / analysis
TL;DR:
The first coupling of a desorption electrospray ionization (DESI) ion source to Fourier transform ion cyclotron resonance mass spectrometry (ESI-FT-ICR-MS) for high-resolution protein analysis is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway
JOURNAL OF BIOLOGICAL CHEMISTRY, 281(52), 39891–39896.
MeSH headings : Cells, Cultured; Down-Regulation / drug effects; Down-Regulation / physiology; Enzyme Activation / physiology; Enzyme Inhibitors / pharmacology; Humans; Interleukin-1 / physiology; Isoenzymes / antagonists & inhibitors; Isoenzymes / biosynthesis; Isoenzymes / physiology; MAP Kinase Kinase Kinases / antagonists & inhibitors; MAP Kinase Kinase Kinases / metabolism; MAP Kinase Kinase Kinases / physiology; Phosphoprotein Phosphatases / antagonists & inhibitors; Phosphoprotein Phosphatases / biosynthesis; Phosphoprotein Phosphatases / physiology; Phosphorylation / drug effects; Signal Transduction / drug effects; Signal Transduction / physiology; Up-Regulation / drug effects
TL;DR:
It is found that toxin inhibition of type 2A protein phosphatases greatly enhances interleukin 1 (IL-1)-dependent phosphorylation of Thr-187 in the TAK1 activation loop as well as the catalytic activity of Tak1.
(via Semantic Scholar)
www.jbc.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Elevated levels of phosphorylated fibrinogen-alpha-isoforms and differential expression of other post-translationally modified proteins in the plasma of ovarian cancer patients
JOURNAL OF PROTEOME RESEARCH, 5(12), 3318–3325.
author keywords: ovarian cancer; biomarker; fibrinogen; two-dimensional gel electrophoresis; mass spectrometry; glycosylation; phosphorylation; protein depletion; Western blot
MeSH headings : Aged; Blood Proteins / analysis; Blotting, Western; Chromatography, High Pressure Liquid; Computational Biology; Electrophoresis, Gel, Two-Dimensional; Female; Fibrinopeptide A / analysis; Humans; Mass Spectrometry; Middle Aged; Ovarian Neoplasms / blood
TL;DR:
This work evaluated the differentially expressed proteins in the plasma of ovarian cancer patients using 2-D SDS-polyacrylamide gel electrophoresis (SDS-PAGE) with post-translational modification (P...
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Status and life-history aspects of Villosa constricta (Conrad 1838) (Notched Rainbow), in the upper Neuse River Basin, North Carolina
SOUTHEASTERN NATURALIST, 5(4), 649–660.
TL;DR:
Stream-survey data, length-at-age study, and host-fish determination for Villosa constricta (notched rainbow) were reported, and lab trials determined that Etheostoma flabellare (fantail darter) served as a suitable host for this species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Resistance of Listeria monocytogenes biofilms to sanitizing agents in a simulated food processing environment
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(12), 7711–7717.
MeSH headings : Bacterial Adhesion / drug effects; Biofilms / drug effects; Biofilms / growth & development; Chlorine / pharmacology; Colony Count, Microbial; Disinfectants / pharmacology; Drug Resistance, Bacterial; Food-Processing Industry / methods; Listeria monocytogenes / drug effects; Listeria monocytogenes / growth & development; Peroxides / pharmacology; Polytetrafluoroethylene; Quaternary Ammonium Compounds / pharmacology; Stainless Steel
TL;DR:
Data suggest that the resistance of the treated biofilms to sanitizing agents may be due to attributes of extracellular polymeric substances and is not an intrinsic attribute of the cells in the biofilm.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Generation and detection of multiply-charged peptides and proteins by matrix-assisted laser desorption electrospray ionization (MALDESI) Fourier transform ion cyclotron resonance mass spectrometry
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 17(12), 1712–1716.
MeSH headings : Algorithms; Cyclotrons; Peptide Mapping / methods; Peptides / analysis; Proteins / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectroscopy, Fourier Transform Infrared / methods; Static Electricity
TL;DR:
Analysis of peptides and proteins resulted in high resolving power single-acquisition FT-ICR mass spectra with average charge-states highly correlated to those obtained by nanoESI, thus, providing strong evidence that the ESI process dictates the observed charge-state distribution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
A comparison of analysis units for associating Lyme disease with forest-edge habitat
COMMUNITY ECOLOGY, 7(2), 189–197.
author keywords: fragmentation; landscape; Maryland; modifiable areal unit problem; negative binomial model; roads; scale; spatial autocorrelation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappa B
JOURNAL OF BIOLOGICAL CHEMISTRY, 281(12), 7863–7872.
MeSH headings : Animals; Cell Line; Cytoplasm / metabolism; Enzyme Activation; Enzyme Inhibitors / pharmacology; Fibroblasts / metabolism; Gene Deletion; Herpesvirus 4, Human / metabolism; Humans; Immunoblotting; MAP Kinase Kinase 4 / metabolism; MAP Kinase Kinase Kinases / metabolism; MAP Kinase Kinase Kinases / physiology; Mice; Mice, Transgenic; Models, Biological; Mutation; NF-kappa B / metabolism; Plasmids / metabolism; Signal Transduction; TNF Receptor-Associated Factor 6 / metabolism; Transfection; Viral Matrix Proteins / metabolism
TL;DR:
Results suggest that an LMP1-associated complex containing TRAF6, TAB2, and TAK1 plays an essential role in the activation of JNK, however, TAK 1 is not an exclusive intermediate for NF-κB activation in L MP1 signaling.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Characterization of a new densovirus infecting the German cockroach, Blattella germanica
JOURNAL OF GENERAL VIROLOGY, 87, 1567–1575.
Contributors: D. Mukha, A. Chumachenko*, M. Dykstra n, T. Kurtti * & C. Schal n
MeSH headings : Animals; Base Sequence; Blattellidae / ultrastructure; Blattellidae / virology; Cell Line; Cloning, Molecular; DNA, Viral / analysis; Densovirus / classification; Densovirus / genetics; Densovirus / isolation & purification; Densovirus / pathogenicity; Genome, Viral; Microscopy, Electron; Molecular Sequence Data; Open Reading Frames; Phylogeny; Sequence Analysis, DNA; Viral Proteins / chemistry; Viral Proteins / genetics
TL;DR:
A new DNA virus (Parvoviridae: Densovirinae, Densovirus) was isolated and purified from descendants of field-collected German cockroaches, Blattella germanica, revealing the presence of extended palindromes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 journal article
A two-stage design for multiple testing in large-scale association studies
JOURNAL OF HUMAN GENETICS, 51(6), 523–532.
author keywords: association studies; cost-effectiveness; false positive rate; multiple testing; two-stage design
MeSH headings : Cost-Benefit Analysis; Data Interpretation, Statistical; False Positive Reactions; Genetic Markers; Genetic Techniques; Genotype; Humans; Hyperlipoproteinemia Type IV / genetics; Models, Genetic; Polymorphism, Single Nucleotide
TL;DR:
The main principle is to reduce the total number of tests by removing clearly unassociated markers in the first-stage test, which may be useful in guiding study design to achieve a high TPR while retaining the desired FPR.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
A quantitative real-time RT-PCR assay to measure TGF-β mRNA and its correlation with hematologic, plasma chemistry and organo-somatic indices responses in triamcinolone-treated Atlantic menhaden, Brevoortia tyrannus
Developmental & Comparative Immunology, 30(5), 473–484.
author keywords: Atlantic menhaden; triamcinolone; TGF-beta; health indices; hematology; plasma chemistry; real-time RT-PCR
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Base Sequence; Blood Glucose / analysis; Fish Diseases / blood; Fish Diseases / immunology; Fish Diseases / metabolism; Fishes / blood; Fishes / immunology; Fishes / metabolism; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / metabolism; Liver / drug effects; Liver / metabolism; Molecular Sequence Data; Plasma; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Skin Ulcer / immunology; Skin Ulcer / metabolism; Skin Ulcer / veterinary; Spleen / drug effects; Spleen / metabolism; Transforming Growth Factor beta / metabolism; Triamcinolone Acetonide / pharmacology
TL;DR:
A quantitative real-time reverse transcription polymerase chain reaction (RT-PCR) assay was developed to measure transforming growth factor-beta (TGF-beta) in Atlantic menhaden, an estuarine-dependent species plagued by ulcerative skin lesions in the estuaries along the eastern United States.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2006 journal article
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate inhibits degranulation of human leukocytes in vitro
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 34(6), 647–652.
author keywords: MARCKS protein; leukocytes; degranulation
MeSH headings : Cell Degranulation; Cell Line; Dose-Response Relationship, Drug; Eosinophil Peroxidase / metabolism; Granzymes; HL-60 Cells; Humans; Killer Cells, Natural; Leukocytes / drug effects; Leukocytes / enzymology; Leukocytes / physiology; Muramidase / metabolism; Neutrophils; Peptide Fragments / pharmacology; Peroxidase / metabolism; Serine Endopeptidases / metabolism; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells
TL;DR:
The results indicate that MARCKS protein may play an important role in the secretion of membrane-bound granules from different leukocytes, and may be an important component of secretory pathways associated with release of granules by different cell types.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells
INTERNATIONAL IMMUNOLOGY, 18(10), 1405–1411.
author keywords: IBD; regulatory T cells; signal transduction; TCR
MeSH headings : Aging / genetics; Aging / immunology; Aging / pathology; Animals; B-Lymphocytes / immunology; B-Lymphocytes / pathology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / pathology; Colitis / genetics; Colitis / immunology; Colitis / pathology; Colitis / prevention & control; Humans; MAP Kinase Kinase Kinases / deficiency; MAP Kinase Kinase Kinases / immunology; MAP Kinase Signaling System / genetics; MAP Kinase Signaling System / immunology; Mice; Mice, Knockout; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / pathology; Thymus Gland / immunology; Thymus Gland / pathology
TL;DR:
The results show that TAK1, by controlling the generation of central Treg cells, is important for preventing spontaneously developing colitis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis
JOURNAL OF BIOLOGICAL CHEMISTRY, 281(28), 19610–19617.
MeSH headings : Animals; Apoptosis; Cytokines / metabolism; Epidermis / metabolism; Gene Deletion; Homeostasis; Inflammation; Keratinocytes / cytology; Keratinocytes / metabolism; MAP Kinase Kinase 4 / metabolism; MAP Kinase Kinase Kinases / physiology; Mice; Mice, Inbred C57BL; NF-kappa B / metabolism; Skin / pathology
TL;DR:
It is demonstrated that TAK1 is the major regulator of skin inflammation as well as keratinocyte death in vivo and is a master regulator of TNF signaling in skin and regulates skin inflammation and keratinocytes death.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Proteomic analysis of cold adaptation in a Siberian permafrost bacterium - Exiguobacterium sibiricum 255-15 by two-dimensional liquid separation coupled with mass spectrometry
PROTEOMICS, 6(19), 5221–5233.
author keywords: 2-D liquid phase separation; bacterial cold adaptation; ESI-TOF MS; MALDI-TOF MS; MALDI-QIT-TOF MS
MeSH headings : Adaptation, Physiological; Amino Acid Sequence; Bacillaceae / metabolism; Chromatography, Liquid; Cold Temperature; Mass Spectrometry; Molecular Sequence Data; Proteome / analysis; Proteome / chemistry; Siberia; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
TL;DR:
Bacterial cold adaptation in Exiguobacterium sibiricum 255–15 was studied on a proteomic scale using a 2‐D liquid phase separation coupled with MS technology to detect cold acclimation proteins (Caps) and homologous cold shock proteins (Csps).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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