Works Published in 2019
Displaying works 61 - 71 of 71 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
The Comparative Toxicogenomics Database: update 2019
NUCLEIC ACIDS RESEARCH, 47(D1), D948–D954.
MeSH headings : Databases, Pharmaceutical; Disease / genetics; Environmental Exposure; Humans; Phenotype; Toxicogenetics; Vocabulary, Controlled
TL;DR:
This biennial update presents a new chemical–phenotype module that codes chemical-induced effects on phenotypes, curated using controlled vocabularies for chemicals, phenotype, taxa, and anatomical descriptors, and describes new querying and display features for the enhanced chemical–exposure science module, providing greater scope of content and utility.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
9. Industry, Innovation and Infrastructure
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 9, 2019
2019 journal article
Improving understanding of carbon storage in wood in landfills: Evidence from reactor studies
WASTE MANAGEMENT, 85, 341–350.
author keywords: Wood; Carbon; Landfill; Methane; Decay; Bacteria
MeSH headings : Australia; Carbon; Methane; Refuse Disposal; Waste Disposal Facilities; Wood
TL;DR:
It is confirmed that disposal of wood in landfills in Australia results in long-term storage of carbon, with only minimal conversion of carbon to gaseous end products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 2, 2019
2019 journal article
Identifying individual risk rare variants using protein structure guided local tests (POINT)
PLOS COMPUTATIONAL BIOLOGY, 15(2).
MeSH headings : Angiopoietin-Like Protein 4 / genetics; Cholesterol Ester Transfer Proteins / genetics; Computational Biology / methods; Computer Simulation; Genetic Association Studies / methods; Genetic Predisposition to Disease / genetics; Genetic Variation / genetics; Humans; Models, Genetic; Proprotein Convertase 9 / genetics; Protein Structure, Tertiary; Risk Factors; Sequence Analysis, DNA / methods
TL;DR:
This work proposes a protein structure guided local test (POINT) to provide variant-specific association information using structure-guided aggregation of signal and assess the selection performance of POINT using simulations and illustrates how it can be used to prioritize individual rare variants in PCSK9, ANGPTL4 and CETP in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) clinical trial data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 25, 2019
2019 journal article
CAD1 and CCR2 protein complex formation in monolignol biosynthesis in Populus trichocarpa
NEW PHYTOLOGIST, 222(1), 244–260.
author keywords: co-immunoprecipitation; enzyme activity; monolignol biosynthetic pathway; nuclear magnetic resonance (NMR); Populus trichocarpa; stem-differentiating xylem protein
MeSH headings : Aldehyde Oxidoreductases / genetics; Aldehyde Oxidoreductases / metabolism; Down-Regulation / genetics; Gene Expression Regulation, Plant; Lignin / metabolism; Magnetic Resonance Spectroscopy; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified; Populus / genetics; Populus / metabolism; RNA Interference; Recombinant Proteins / metabolism; Xylem / metabolism
TL;DR:
Evidence is provided for the formation of PtrCAD1/PtrCCR2 protein complexes in monolignol biosynthesis in planta, and biomolecular fluorescence complementation and pull-down/co-immunoprecipitation experiments supported a hypothesis of P Tr trichocarpa heterodimer formation.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 18, 2019
2019 journal article
Solid Waste Management Policy Implications on Waste Process Choices and Systemwide Cost and Greenhouse Gas Performance
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 53(4), 1766–1775.
MeSH headings : Cities; Greenhouse Effect; Greenhouse Gases; Humans; North Carolina; Refuse Disposal; Solid Waste; Waste Management
TL;DR:
This analysis evaluated cost and select environmental implications of SWM policies for Wake County, North Carolina using a life-cycle approach and found that maintaining the current separate collection scheme limited the potential for cost and GHG reductions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 11, 2019
2019 journal article
Binding of peanut allergen Ara h 2 with Vaccinium fruit polyphenols
FOOD CHEMISTRY, 284, 287–295.
author keywords: Ara h 2; Molecular docking; Polyphenol; IgE binding; Circular dichroism (CD); Food allergy
MeSH headings : 2S Albumins, Plant / chemistry; 2S Albumins, Plant / immunology; 2S Albumins, Plant / metabolism; Antigens, Plant / chemistry; Antigens, Plant / immunology; Antigens, Plant / metabolism; Arachis / metabolism; Biflavonoids / chemistry; Biflavonoids / metabolism; Binding Sites; Catechin / chemistry; Catechin / metabolism; Chlorogenic Acid / chemistry; Chlorogenic Acid / metabolism; Circular Dichroism; Epitopes / chemistry; Epitopes / metabolism; Fruit / chemistry; Fruit / metabolism; Glycoproteins / chemistry; Glycoproteins / immunology; Glycoproteins / metabolism; Humans; Immunoglobulin E / chemistry; Immunoglobulin E / metabolism; Molecular Docking Simulation; Polyphenols / chemistry; Polyphenols / metabolism; Proanthocyanidins / chemistry; Proanthocyanidins / metabolism; Protein Binding; Protein Structure, Secondary; Spectrophotometry; Vaccinium / chemistry; Vaccinium / metabolism
TL;DR:
Results suggest that certain polyphenols can inhibit IgE recognition of Ara h 2 by obstructing linear IgE epitopes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 25, 2019
2019 journal article
Discriminating normal regions within cancerous hen ovarian tissue using multivariate hyperspectral image analysis
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 33(4), 381–391.
MeSH headings : Animals; Chickens / metabolism; Female; Least-Squares Analysis; Multivariate Analysis; Ovarian Neoplasms / chemistry; Ovarian Neoplasms / diagnosis; Ovarian Neoplasms / pathology; Ovarian Neoplasms / veterinary; Ovary / chemistry; Ovary / pathology; Poultry Diseases / diagnosis; Poultry Diseases / pathology; Principal Component Analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR:
Two unsupervised chemometric methods including PCA and MCR-ALS were applied for resolving and visualizing IR-MALDESI-MS data acquired from hen ovary tissues, improving the interpretation of mass spectrometry imaging results.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 18, 2019
2019 journal article
Characterizing sources of variability in zebrafish embryo screening protocols
ALTEX, 36(1), 103–120.
MeSH headings : Animals; Chorion / metabolism; Drug Evaluation, Preclinical / methods; Embryo, Nonmammalian; Embryonic Development / drug effects; High-Throughput Screening Assays; Toxicity Tests / methods; Zebrafish / embryology
TL;DR:
Initial SEAZIT information-gathering efforts revealed substantial variability across design parameters, data collected, and analysis procedures, which provides a basis for future SEAZit activities to promote more consistent practices among researchers using zebrafish embryos for toxicity evaluation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, Crossref
Added: January 21, 2019
2019 journal article
Elevated metabolites of acetaminophen in cord blood of children with obesity
PEDIATRIC OBESITY, 14(1).
Contributors: P. Sorrow n, R. Maguire n, S. Murphy *, S. Belcher n & C. Hoyo n
author keywords: Acetaminophen; children; metabolomics; obesity
MeSH headings : Acetaminophen / blood; Acetaminophen / metabolism; Case-Control Studies; Child, Preschool; Fatty Acids / blood; Female; Fetal Blood / metabolism; Humans; Male; Metabolomics / methods; Pediatric Obesity / blood; Pregnancy
TL;DR:
High‐throughput metabolomics has been used cross‐sectionally to evaluate differential metabolic profiles associated with human obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 7, 2019
2019 journal article
Are sulfate effects in the mayfly Neocloeon triangulifer driven by the cost of ion regulation?
author keywords: salinity stress; ion transport; mayfly; development; freshwater ecosystem
MeSH headings : Animals; Dose-Response Relationship, Drug; Ephemeroptera / drug effects; Ephemeroptera / growth & development; Ephemeroptera / physiology; Fresh Water / chemistry; Ion Transport / physiology; Larva / drug effects; Larva / growth & development; Larva / physiology; Sulfates / adverse effects; Water Pollutants, Chemical / adverse effects
TL;DR:
Evaluating the performance of the mayfly Neocloeon triangulifer reared for its entire larval phase in a gradient of sulfate concentrations suggested that elevated SO4 imposes an energetic demand associated with maintaining homeostasis that is manifested primarily as reduced growth rates and associated developmental delays.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: December 31, 2018
2019 journal article
Discovery and quantification of bioactive peptides in fermented cucumber by direct analysis IR-MALDESI mass spectrometry and LC-QQQ-MS
FOOD CHEMISTRY, 271, 715–723.
author keywords: Lactic acid fermentation; ACE-inhibitory peptides; Isoleucine-proline-proline; Leucine-proline-proline; Valine-proline-proline; Vegetable composition
MeSH headings : Cucumis sativus / chemistry; Fermentation; Peptides / chemistry; Sodium Chloride; Tandem Mass Spectrometry
TL;DR:
It is demonstrated that lactic acid bacteria fermentation can enhance bioactive peptide content in vegetables by 3-5 fold in fermented cucumbers compared with acidified cucumbers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018
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