Works Published in 2023
Displaying works 201 - 214 of 214 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2023 journal article
Leveraging Scheme for Cross-Study Microbiome Machine Learning Prediction and Feature Evaluations
BIOENGINEERING-BASEL, 10(2).
author keywords: feature selection; machine learning; microbiome; random forest; support vector machine; logistic regression
TL;DR:
This study developed a method for improving the generalizability and interpretability of machine learning models for predicting three different diseases (colorectal cancer, Crohn’s disease, and immunotherapy response) using nine independent microbiome datasets using random forest as the top model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 10, 2023
2023 article
Loss of Heterozygosity and Its Importance in Evolution
Heil, C. S. (2023, February 8). JOURNAL OF MOLECULAR EVOLUTION, Vol. 2.
author keywords: Loss of heterozygosity; Experimental evolution; Saccharomyces; Hybrids
TL;DR:
Advances in understanding dominance, fitness, and phenotypes in laboratory evolved heterozygous yeast strains are highlighted.
(via Semantic Scholar)
link.springer.com (publisher PDF)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 9, 2023
2023 article
Morphological and sensorimotor phenotypes in a zebrafish CHARGE syndrome model are domain-dependent
Hodorovich, D. R. R., Lindsley, P. M. M., Berry, A. A. A., Burton, D. F. F., & Marsden, K. C. C. (2023, January 30). GENES BRAIN AND BEHAVIOR, Vol. 1.
author keywords: behavior; CHARGE syndrome; chd7; CRISPR; Cas9; zebrafish
MeSH headings : Animals; CHARGE Syndrome / genetics; CHARGE Syndrome / metabolism; Zebrafish / genetics; Zebrafish / metabolism; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Reflex, Startle; Phenotype; Mutation
TL;DR:
A mutant chd7 zebrafish line is established using CRISPR/Cas9 that recapitulates multiple CHARGE phenotypes and it is shown that the penetrance of morphological and behavioral phenotypes depends on the mutation location.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 31, 2023
2023 journal article
Salinity-induced ionoregulatory changes in the gill proteome of the mayfly, Neocloeon triangulifer
ENVIRONMENTAL POLLUTION, 316.
author keywords: Proteomics; Salinity; Mayfly; Gill biology; Ion transport; Osmoregulation
MeSH headings : Animals; Ephemeroptera; Gills / metabolism; Salinity; Proteome / metabolism; Sodium Chloride / metabolism; Proteomics; Calcium Chloride; Water Pollutants, Chemical / metabolism; Aquatic Organisms / metabolism; Sodium-Potassium-Exchanging ATPase / metabolism; Ions / metabolism; Water / metabolism
TL;DR:
The breadth of physiological functions in gills is demonstrated by exploring non-transport related pathways found in the dataset, including ATP synthesis, calcium signaling, and oxidative stress response, and the challenges of working with non-model species without fully sequenced and annotated genomes are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 30, 2023
2023 journal article
Timing and Trends for Municipal Wastewater, Lab-Confirmed Case , and Syndromic Case Surveillance of COVID-19 in Raleigh, North Carolina
AMERICAN JOURNAL OF PUBLIC HEALTH, 113(1), 79–88.
MeSH headings : Humans; COVID-19 / epidemiology; SARS-CoV-2; Wastewater; North Carolina / epidemiology; Sentinel Surveillance; RNA, Viral
TL;DR:
The results provide evidence for investment in SARS-CoV-2 wastewater and CLI surveillance to complement information provided through lab-confirmed cases, and in a major metropolitan area in 2020, the timing of and trends in municipal wastewater, lab- confirmed case, and syndromic case surveillance of COVID-19 were in general agreement.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 30, 2023
2023 article
A new role of TRPM8 in circadian rhythm and molecular clock
Mishra, S. K., & Gaddameedhi, S. (2023, January 20). ACTA PHYSIOLOGICA, Vol. 1.
MeSH headings : Circadian Rhythm; Circadian Clocks
TL;DR:
Evidence is provided that TRPM8 might regulate Period 2 (Per2) mRNA levels in central clock (SCN) and peripheral clock (liver and white adipose tissue) and the circadian regulation of core body temperature and the most significant advances in the field of circadian regulation using cold sensors are provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 21, 2023
2023 journal article
Total mercury, methylmercury, and selenium concentrations in blue marlin Makaira nigricans from a long-term dataset in the western north Atlantic
SCIENCE OF THE TOTAL ENVIRONMENT, 858.
author keywords: Marine apex predator; Neurotoxicant; Mercury; Methylmercury; Selenium; Human health; Fish consumption
MeSH headings : Animals; Humans; Mercury / analysis; Methylmercury Compounds; Selenium; Water Pollutants, Chemical / analysis; Fishes; Perciformes
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 9, 2023
2023 article
Bayesian matrix completion for hypothesis testing
Jin, B., Dunson, D. B., Rager, J. E., Reif, D. M., Engel, S. M., & Herring, A. H. (2023, March 15). JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, Vol. 3.
author keywords: Bayesian hierarchical model; bioactivity profiles; chemical screening; heteroscedasticity; latent factor models; ToxCast; Tox21
TL;DR:
This paper makes a novel attempt in toxicology to simultaneously model heteroscedastic errors and a nonparametric mean function, leading to a broader definition of activity whose need has been suggested by toxicologists.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 4, 2023
2023 journal article
TCDD alters essential transcriptional regulators of osteogenic differentiation in multipotent mesenchymal stem cells
Toxicological Sciences.
author keywords: mesenchymal stem cell; AhR; cell differentiation
MeSH headings : Humans; Osteogenesis / genetics; Polychlorinated Dibenzodioxins / toxicity; Cell Differentiation; Fibroblast Growth Factors / metabolism; Mesenchymal Stem Cells / metabolism; Cells, Cultured; Osteoblasts
TL;DR:
A global transcriptomic landscape during early, intermediate, and apical stages of osteogenic differentiation in vitro in response to TCDD is established to identify novel pathways and transcription factors that may facilitate a better understanding of the osteoblast differentiation process, perturbation by exogenous agents, and potential intervention strategies targeting those specific pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: November 12, 2022
2023 journal article
The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease
Toxicological Sciences.
author keywords: nonalcoholic fatty liver disease; developmental toxicology; epigenetics; cadmium; genomic imprinting; developmental programming
MeSH headings : Mice; Animals; Non-alcoholic Fatty Liver Disease / genetics; Non-alcoholic Fatty Liver Disease / metabolism; Cadmium; Cadmium Chloride / toxicity; PPAR gamma; Liver / metabolism; Fibrosis
TL;DR:
It is demonstrated that developmental Cd exposure is sufficient to program NAFLD in later life, and Zac1 and the IGN are established as key regulators of prosteatotic and profibrotic pathways, two of the major pathological hallmarks ofNAFLD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: October 29, 2022
2023 journal article
Source apportionment of serum PFASs in two highly exposed communities
SCIENCE OF THE TOTAL ENVIRONMENT, 855.
author keywords: Source apportionment; Receptor models; PFAS; Per fluoroalkyl substances
MeSH headings : Humans; Fluorocarbons / analysis; Nutrition Surveys; Drinking Water / analysis; Multivariate Analysis; Principal Component Analysis; Alkanesulfonic Acids / analysis; Water Pollutants, Chemical / analysis
TL;DR:
Effectiveness of three source apportionment methods for identifying contributors to human serum PFAS concentrations in two highly exposed populations in Colorado and North Carolina where drinking water was contaminated via upstream sources is assessed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 11, 2022
2023 journal article
Chronic fracture and osteomyelitis in a large‐bodied ornithomimosaur with implications for the identification of unusual endosteal bone in the fossil record
The Anatomical Record.
author keywords: dinosaur; fracture; infection; medullary bone; theropod
MeSH headings : Animals; Fossils; Bone and Bones; Fractures, Bone / diagnostic imaging; X-Ray Microtomography; Osteomyelitis / diagnostic imaging
TL;DR:
The external gross morphology and internal architecture of a pathologic right second metatarsal of a large‐bodied ornithomimid from the Santonian (Upper Cretaceous) Eutaw Formation in Mississippi is described, interpreted as evidence of blunt force trauma to the foot that could have resulted from intra‐ or interspecific competition or predator–prey interaction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: ORCID
Added: October 4, 2022
2023 journal article
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction
Epigenetics.
author keywords: Genomic imprinting; imprinted genes; DNA methylation; placenta; cadmium; foetal growth restriction; CDKN1C; toxic metal
TL;DR:
It is concluded that the Cd-associated increase in Cdkn1c expression can be fully explained by alterations to placental structure, and it is shown that CdKn1c is expressed primarily in the placental labyrinth which is proportionally increased in size in response to Cd.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: September 28, 2022
2023 journal article
Estimating ancient biogeographic patterns with statistical model discrimination
The Anatomical Record.
author keywords: biogeography; dinosaur; ecology; linear regression; phylogenetics
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: ORCID
Added: September 25, 2022
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