Works Published in 2007
Displaying works 1 - 20 of 25 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2007 journal article
Tissue Doppler Imaging in Maine Coon Cats with a Mutation of Myosin Binding Protein C with or without Hypertrophy
Journal of Veterinary Internal Medicine, 21(2), 232–237.
onlinelibrary.wiley.com (publisher PDF)
Sources: NC State University Libraries, NC State University Libraries
Added: October 18, 2020
2007 chapter
Lamb A Ambulatory electrocardiography
In Five-Minute Veterinary Consult (pp. 312–314). Ames: Diagnostic Procedures and Laboratory Tests Blackwell Publishing.
Source: NC State University Libraries
Added: October 10, 2020
2007 chapter
Boxer Cardiomyopathy
In Five Minute Veterinary Consult (pp. 206–208). Ames: Blackwell Publishing.
Source: NC State University Libraries
Added: October 10, 2020
2007 journal article
Pharmacokinetic Modeling of Manganese. II. Hepatic Processing After Ingestion and Inhalation
Journal of Toxicology and Environmental Health, Part A, 70(18), 1505–1514.
MeSH headings : Administration, Inhalation; Administration, Oral; Animals; Intestinal Absorption; Intestinal Mucosa / metabolism; Liver / metabolism; Male; Manganese / pharmacokinetics; Models, Biological; Rats; Rats, Inbred Strains
TL;DR:
Differences in hepatic processing of blood Mn derived from different dose routes need to be accounted for in more complete PK models for Mn that are intended to support human health risk assessments.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Pharmacokinetic Modeling of Manganese. I. Dose Dependencies of Uptake and Elimination
Journal of Toxicology and Environmental Health, Part A, 70(18), 1493–1504.
MeSH headings : Animals; Bile / chemistry; Dose-Response Relationship, Drug; Intestinal Mucosa / metabolism; Liver / metabolism; Male; Manganese / pharmacokinetics; Mice; Models, Biological; Rats; Rats, Inbred Strains
TL;DR:
D dose dependencies in uptake and elimination are necessary inputs for comprehensive PK models guiding human health risk assessments with Mn, and differential control of absorption in single gavage oral dose studies versus continuous high oral doses in the feed is indicated.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Basal Gene Expression in Male and Female Sprague-Dawley Rat Nasal Respiratory and Olfactory Epithelium
Inhalation Toxicology, 19(11), 941–949.
MeSH headings : Animals; Female; Gene Expression Profiling / methods; Gene Expression Regulation / physiology; Male; Nasal Mucosa / metabolism; Nasal Mucosa / physiology; Nasal Mucosa / ultrastructure; Olfactory Mucosa / metabolism; Olfactory Mucosa / physiology; Olfactory Mucosa / ultrastructure; Rats; Rats, Sprague-Dawley; Xenobiotics / metabolism
TL;DR:
To better understand and predict gender differences in response of the nasal epithelium to inhaled xenobiotics, gene expression profiles from naive male and female Sprague-Dawley rats were constructed and surprisingly, there were few gender Differences in gene expression.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Inhibition and recovery of maternal and foetal cholinesterase enzymes following fenitrothion administration in CD rats
Xenobiotica, 37(1), 19–29.
author keywords: toxicology; pharmacokinetics; fenitrothion; neurotoxicity; esterases; rodent
MeSH headings : Animals; Brain / drug effects; Brain / enzymology; Cholinesterase Inhibitors / administration & dosage; Cholinesterase Inhibitors / blood; Cholinesterase Inhibitors / pharmacokinetics; Cholinesterase Inhibitors / pharmacology; Cholinesterases / metabolism; Female; Fenitrothion / administration & dosage; Fenitrothion / blood; Fenitrothion / pharmacokinetics; Fenitrothion / pharmacology; Fetus / drug effects; Fetus / enzymology; Liver / drug effects; Liver / enzymology; Pregnancy; Rats
TL;DR:
Esterase inhibition occurred at a fenitrothion dose that has not been previously associated with reproductive toxicity, suggesting that esterase inhibition should be considered as the critical effect in risk assessments for this pesticide.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Preliminary investigation of changes in the sexually dimorphic nucleus of the rat medial preoptic area following prenatal exposure to fenitrothion
Journal of Applied Toxicology, 27(6), 631–636.
author keywords: anti-androgen; SDN-POA; fenitrothion; developmental neurotoxicity
MeSH headings : Administration, Oral; Androgen Antagonists / administration & dosage; Androgen Antagonists / toxicity; Animals; Body Weight / drug effects; Cholinesterase Inhibitors / administration & dosage; Cholinesterase Inhibitors / toxicity; Dose-Response Relationship, Drug; Female; Fenitrothion / administration & dosage; Fenitrothion / toxicity; Gait / drug effects; Insecticides / administration & dosage; Insecticides / toxicity; Lacrimal Apparatus / drug effects; Lacrimal Apparatus / metabolism; Litter Size / drug effects; Male; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area / drug effects; Preoptic Area / growth & development; Preoptic Area / pathology; Rats; Sexual Maturation; Tears / metabolism; Tremor / chemically induced
TL;DR:
There was a dose‐related increase in the SDN‐POA volume in males and a dose-related decrease in SDN-POAVolume in females exposed to fenitrothion, suggesting that fen itrothion may have mixed endocrine effects on the developing brain.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Basal ganglia neurotransmitter concentrations in rhesus monkeys following subchronic manganese sulfate inhalation
American Journal of Industrial Medicine, 50(10), 772–778.
author keywords: parkinsonism; neurochemistry; inhalation; macaca mulatta; manganese
MeSH headings : 3,4-Dihydroxyphenylacetic Acid / metabolism; Animals; Basal Ganglia / drug effects; Basal Ganglia / metabolism; Disease Models, Animal; Dopamine / metabolism; Glutamic Acid / metabolism; Hydroxyindoleacetic Acid / metabolism; Inhalation; Macaca mulatta; Manganese Compounds / analysis; Neurotransmitter Agents / analysis; Neurotransmitter Agents / metabolism; Norepinephrine / metabolism; Parkinsonian Disorders / physiopathology; Serotonin / metabolism; Sulfates / analysis; Sulfates / toxicity; gamma-Aminobutyric Acid / metabolism
TL;DR:
Despite the presence of increased tissue manganese concentrations, high-dose exposure to MnSO4 was associated with relatively few changes in basal ganglial neurotransmitter concentrations.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
A substitution mutation in the myosin binding protein C gene in ragdoll hypertrophic cardiomyopathy
Genomics, 90(2), 261–264.
author keywords: hypertrophic cardiomyopathy; feline; myosin binding protein C; cardiac
MeSH headings : Amino Acid Sequence; Amino Acid Substitution; Animals; Cardiomyopathy, Hypertrophic / genetics; Carrier Proteins / genetics; Cats; DNA, Recombinant; Disease Models, Animal; Exons; Molecular Sequence Data; Point Mutation
TL;DR:
The identification of two separate mutations within this gene in unrelated breeds suggests that these mutations occurred independently rather than being passed on from a common founder.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 16, 2019
2007 journal article
Desmosomal gene evaluation in Boxers with arrhythmogenic right ventricular cardiomyopathy
American Journal of Veterinary Research, 68(12), 1338–1341.
MeSH headings : Animals; Arrhythmogenic Right Ventricular Dysplasia / genetics; Arrhythmogenic Right Ventricular Dysplasia / veterinary; Base Sequence; Desmoglein 2 / genetics; Desmoplakins / genetics; Desmosomes / genetics; Dog Diseases / genetics; Dogs; Exons / genetics; Female; Genetic Predisposition to Disease; Male; Multigene Family; Plakophilins / genetics; RNA Splice Sites / genetics; gamma Catenin / genetics
Sources: Crossref, NC State University Libraries
Added: December 16, 2019
2007 journal article
A Prospective Genetic Evaluation of Familial Dilated Cardiomyopathy in the Doberman Pinscher
Journal of Veterinary Internal Medicine, 21(5), 1016–1020.
Sources: Crossref, NC State University Libraries
Added: December 16, 2019
2007 journal article
Evaluation of serum cardiac troponin I concentration in Boxers with arrhythmogenic right ventricular cardiomyopathy
American Journal of Veterinary Research, 68(5), 524–528.
MeSH headings : Animals; Arrhythmogenic Right Ventricular Dysplasia / blood; Arrhythmogenic Right Ventricular Dysplasia / metabolism; Arrhythmogenic Right Ventricular Dysplasia / veterinary; Dog Diseases / blood; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Female; Male; Troponin I / blood; Troponin I / genetics
TL;DR:
Compared with clinically normal dogs, Boxers with ARVC had a significant increase in serum cTnI concentration, and correlated with severity of disease in terms of degree of myocardial fibrofatty changes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 16, 2019
2007 journal article
Double Chambered Right Ventricle in 9 Cats
Journal of Veterinary Internal Medicine, 21(1), 76–80.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 16, 2019
2007 journal article
Results of the veterinary enalapril trial to prove reduction in onset of heart failure in dogs chronically treated with enalapril alone for compensated, naturally occurring mitral valve insufficiency
Journal of the American Veterinary Medical Association, 231(7), 1061–1069.
MeSH headings : Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Antihypertensive Agents / therapeutic use; Death, Sudden, Cardiac / veterinary; Disease Progression; Disease-Free Survival; Dog Diseases / mortality; Dog Diseases / prevention & control; Dogs; Double-Blind Method; Enalapril / therapeutic use; Female; Heart Failure / mortality; Heart Failure / prevention & control; Heart Failure / veterinary; Kaplan-Meier Estimate; Male; Mitral Valve Insufficiency / complications; Mitral Valve Insufficiency / veterinary; Severity of Illness Index; Time Factors; Treatment Outcome
TL;DR:
Chronic enalapril treatment of dogs with naturally occurring, moderate to severe MR significantly delayed onset of CHF, compared with placebo, on the basis of number ofCHF-free days, number of dogs free of CHFs at days 500 and study end, and increased time to a combined secondary endpoint of CHf-all-cause death.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2007 journal article
Morphology and correction of distal tibial valgus deformities
JOURNAL OF SMALL ANIMAL PRACTICE, 48(12), 678–682.
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / epidemiology; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Female; Joint Deformities, Acquired / surgery; Joint Deformities, Acquired / veterinary; Male; North Carolina / epidemiology; Osteotomy / veterinary; Radiography; Retrospective Studies; Tibia / surgery
TL;DR:
Many distal tibial valgus deformities in dogs are a uniplanar deformity without concurrent craniocaudal or rotational changes or length deficits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Fibroblast growth factor-binding protein and N-deacetylase/N-sulfotransferase-1 expression in type II cells is modulated by heparin and extracellular matrix
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 293(5), L1314–L1320.
author keywords: coculture; alveolus; sulfation
MeSH headings : Animals; Carrier Proteins / genetics; Carrier Proteins / metabolism; Cells, Cultured; Extracellular Matrix / metabolism; Fibroblasts / cytology; Fibroblasts / metabolism; Heparin / pharmacology; Intercellular Signaling Peptides and Proteins; Lung / cytology; Lung / metabolism; Pulmonary Alveoli / cytology; Pulmonary Alveoli / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sulfotransferases / genetics; Sulfotransferases / metabolism
TL;DR:
Results demonstrate a potentially important modulatory influence of sulfated ECMs and fibroblasts on FGF-BP and NDST-1 at the gene expression level and demonstrate that performed ECM appears to supply factors that modify subsequent treatment effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis
CANCER RESEARCH, 67(20), 9713–9720.
MeSH headings : Animals; Carcinogens; Carcinoma, Squamous Cell / enzymology; Carcinoma, Squamous Cell / metabolism; Carcinoma, Squamous Cell / pathology; Cell Transformation, Neoplastic / metabolism; Cell Transformation, Neoplastic / pathology; Cyclin-Dependent Kinase 2 / deficiency; Cyclin-Dependent Kinase 2 / metabolism; Cyclin-Dependent Kinase 4 / metabolism; Cyclin-Dependent Kinase Inhibitor p21 / metabolism; Cyclin-Dependent Kinase Inhibitor p27 / metabolism; Disease Progression; Enzyme Activation; Female; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-myc / biosynthesis; Proto-Oncogene Proteins c-myc / genetics; Proto-Oncogene Proteins c-myc / metabolism; Skin Neoplasms / chemically induced; Skin Neoplasms / enzymology; Skin Neoplasms / pathology; Tetradecanoylphorbol Acetate; ras Proteins / metabolism
TL;DR:
Overall, it is established that ras-induced tumors are more susceptible to CDK2 ablation than myc-induced tumorigenesis, suggesting that the efficacy of targetingCDK2 in tumor development and malignant progression is dependent on the oncogenic pathway involved.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Parotid duct sialolithiasis in a dog
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 43(1), 45–51.
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Female; Parotid Diseases / diagnostic imaging; Parotid Diseases / surgery; Parotid Diseases / veterinary; Salivary Duct Calculi / diagnostic imaging; Salivary Duct Calculi / surgery; Salivary Duct Calculi / veterinary; Tomography, X-Ray Computed / veterinary; Treatment Outcome
TL;DR:
Computed tomography was used to evaluate a 7-year-old English bulldog with a history of facial swelling and to aid in the diagnosis of parotid duct sialolithiasis, revealing glandular atrophy and fibrosis with lymphoplasmacytic inflammation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Antibiotic-resistant Corynebacterium jeikeium urinary tract infection in a cat
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 43(1), 61–64.
MeSH headings : Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacology; Bacteriuria / microbiology; Cat Diseases / drug therapy; Cat Diseases / microbiology; Cats; Corynebacterium / drug effects; Corynebacterium / genetics; Corynebacterium / isolation & purification; Corynebacterium Infections / drug therapy; Corynebacterium Infections / microbiology; Corynebacterium Infections / veterinary; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors / administration & dosage; Enzyme Inhibitors / pharmacology; Male; Microbial Sensitivity Tests / veterinary; RNA, Ribosomal, 16S / genetics; Treatment Outcome; Urinary Tract Infections / drug therapy; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
TL;DR:
Urine culture and gene sequencing identified Corynebacterium jeikeium, which was resistant to antibiotics and appeared to be the cause of the urinary tract infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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