College of Veterinary Medicine - General

Works Published in 2013

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Displaying all 17 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2013 chapter

Cardiomyopathy in the boxer dog

In Current Veterinary Therapy (Small Animal Practice) XV. Philadelphia: WB Saunders.

By: K. Meurs

Source: NC State University Libraries
Added: October 10, 2020

2013 journal article

Identification of DNA variants in the canine beta-1 adrenergic receptor gene

Research in Veterinary Science, 95(1), 238–240.

By: B. Maran, K. Mealey, S. Lahmers, O. Nelson & K. Meurs*

author keywords: Pharmacogenomic; Beta blocker; Cardiac
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; DNA / chemistry; DNA / genetics; Dogs / genetics; Genetic Variation; Molecular Sequence Data; Polymerase Chain Reaction / veterinary; Receptors, Adrenergic, beta-1 / genetics; Sequence Alignment
TL;DR: Two deletions were identified within the region of the gene that encodes the cytoplasmic tail of ADRB1, which is important in differentiating subtypes of adrenergic receptors and may be associated with control of receptor downregulation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: November 16, 2019

2013 journal article

Hybrid cutting balloon dilatation for treatment of cor triatriatum sinister in a cat

JOURNAL OF VETERINARY CARDIOLOGY, 15(3), 205–210.

author keywords: Sinistrum; Pulmonary venous anomaly; Feline; Congenital heart disease; Dilatation
MeSH headings : Angioplasty, Balloon, Coronary / methods; Angioplasty, Balloon, Coronary / veterinary; Animals; Cat Diseases / diagnosis; Cat Diseases / therapy; Cats; Cor Triatriatum / diagnosis; Cor Triatriatum / therapy; Cor Triatriatum / veterinary; Echocardiography, Transesophageal / veterinary; Female
TL;DR: Based upon the outcome of this case, balloon dilatation appears to be a viable treatment option for cats affected with cor triatriatum sinister. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

EFFICACY OF ALFAXALONE FOR INTRAVASCULAR ANESTHESIA AND EUTHANASIA IN BLUE CRABS (CALLINECTES SAPIDUS)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 44(3), 694–699.

By: L. Minter n, C. Harms*, K. Archibald*, H. Broadhurst, K. Bailey, E. Christiansen*, G. Lewbart*, L. Posner

author keywords: Alfaxalone; Alfaxan (R); anesthetic; blue crab; Callinectes sapidus; euthanasia
MeSH headings : Anesthetics / pharmacology; Animals; Brachyura; Euthanasia, Animal / methods; Female; Pregnanediones / pharmacology
TL;DR: In summary, the intravascular administration of alfaxalone at 15 mg/kg provided rapid and reliable sedation, whereasAlfaxalone administered at 100mg/kg produced rapid and long lasting anesthesia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Association of Dilated Cardiomyopathy with the Striatin Mutation Genotype in Boxer Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1437–1440.

By: K. Meurs n, J. Stern n, D. Sisson*, M. Kittleson*, S. Cunningham*, M. Ames n, C. Atkins n, T. DeFrancesco n ...

author keywords: Boxer; Dilated cardiomyopathy; Mutation; Striatin
MeSH headings : Animals; Arrhythmogenic Right Ventricular Dysplasia / genetics; Arrhythmogenic Right Ventricular Dysplasia / physiopathology; Arrhythmogenic Right Ventricular Dysplasia / veterinary; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / physiopathology; Cardiomyopathy, Dilated / veterinary; Case-Control Studies; Confidence Intervals; DNA / chemistry; DNA / genetics; Dog Diseases / genetics; Dog Diseases / physiopathology; Dogs; Echocardiography / veterinary; Female; Genotype; Male; Membrane Proteins / genetics; Polymerase Chain Reaction / veterinary; Sequence Deletion / genetics
TL;DR: This study demonstrates an association between DCM in the Boxer dog and the striatin mutation, particularly with the homozygous genotype, and suggests that there is at least 1 other cause of DCm in the boxer dog. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

pH Dynamics of Tricaine Methanesulfonate (MS-222) in Fresh and Artificial Seawater

NORTH AMERICAN JOURNAL OF AQUACULTURE, 75(3), 356–360.

UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

In vitro comparison of the effectiveness of polihexanide and chlorhexidine against canine isolates of Staphylococcus pseudintermedius, Pseudomonas aeruginosa and Malassezia pachydermatis

Veterinary Dermatology, 24(4), 409–489.

By: F. Banovic, F. Bozic & N. Lemo

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Expression of Fibroblast Growth Factor 9 in Normal Human Lung and Idiopathic Pulmonary Fibrosis

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 61(9), 671–679.

author keywords: smooth muscle cells; myofibroblast; metaplastic epithelium
MeSH headings : Adult; Cells, Cultured; Fibroblast Growth Factor 9 / analysis; Fibroblast Growth Factor 9 / metabolism; Humans; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Immunohistochemistry; Lung / metabolism; Lung / pathology; Lung / ultrastructure; Myocytes, Smooth Muscle / metabolism; Myocytes, Smooth Muscle / pathology; Myocytes, Smooth Muscle / ultrastructure; Myofibroblasts / metabolism; Myofibroblasts / pathology; Myofibroblasts / ultrastructure
TL;DR: Lungs of IPF patients expressed FGF9 in a population of myofibroblasts within fibroblastic foci, hypertrophic and hyperplastic epithelium of airways and alveoli, and smooth muscle cells surrounding vessels embedded in thickened interstitium, demonstrating a potentially strong candidate for contributing to the progression of IPf. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Outcomes and Complications Associated With Epicardial Pacemakers in 28 Dogs and 5 Cats

VETERINARY SURGERY, 42(5), 544–550.

MeSH headings : Animals; Arrhythmias, Cardiac / therapy; Arrhythmias, Cardiac / veterinary; Cat Diseases / therapy; Cats; Dog Diseases / therapy; Dogs; Female; Male; Pacemaker, Artificial / veterinary; Retrospective Studies; Treatment Outcome
TL;DR: Larger dogs (>10 kg) may be predisposed to more major complications with epicardial pacemaker (EP) implantation, and therefore implantation of EPs remains a suitable alternative. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Assessment of geographical variation in the respiratory toxicity of desert dust particles

INHALATION TOXICOLOGY, 25(7), 405–416.

By: K. Taylor n, M. Foster n, J. Law n, J. Centeno*, E. Fornero*, M. Henderson n, S. Trager n, M. Stockelman*, D. Dorman n

author keywords: Cytotoxicity; dust inhalation; in vitro; in vivo; particle toxicity; pulmonary toxicity; rat
MeSH headings : Administration, Inhalation; Afghanistan; Animals; Arsenic / analysis; Arsenic / toxicity; Bronchoalveolar Lavage Fluid / chemistry; Bronchoalveolar Lavage Fluid / cytology; Cell Count; Cell Line; Cell Survival / drug effects; Cytokines / metabolism; Dust / analysis; Endotoxins / analysis; Endotoxins / toxicity; Geography; Iraq; L-Lactate Dehydrogenase / metabolism; Lung / drug effects; Lung / metabolism; Lung / pathology; Male; Metals / analysis; Metals / toxicity; Rats; Silicon Dioxide / analysis; Silicon Dioxide / toxicity; United States
TL;DR: The in vitro cytotoxicity assay results were partially predictive of in vivo responses and could be used to prioritize future particle inhalation studies or guide epidemiological study design. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Extent of linkage disequilibrium in large-breed dogs: chromosomal and breed variation

MAMMALIAN GENOME, 24(9-10), 409–415.

MeSH headings : Animals; Breeding; Chromosomes, Mammalian / genetics; Dogs / genetics; Female; Genetic Markers; Genome-Wide Association Study; Haplotypes; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide
TL;DR: This is the first reported of SNP-based LD for Newfoundland dogs, the first report based on genome-wide SNPs for Rottweilers, and an almost tenfold improvement in marker density over previous genome- wide studies of LD in Golden Retrievers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Assessment of Plasma Concentrations and Potential Adverse Effects of Doxycycline in Cockatiels (Nymphicus hollandicus) Fed a Medicated Pelleted Diet

JOURNAL OF AVIAN MEDICINE AND SURGERY, 27(3), 187–193.

By: K. Flammer n, J. Massey n, T. Roudybush, C. Meek n & M. Papich n

author keywords: Chlamydophila psittaci; spiral bacteria; antimicrobial drug; doxycycline; pharmacology; avian; cockatiel; Nymphicus hollandicus
MeSH headings : Animal Feed / analysis; Animals; Anti-Bacterial Agents / adverse effects; Anti-Bacterial Agents / blood; Cockatoos / blood; Doxycycline / adverse effects; Doxycycline / blood; Food Handling; Time Factors
TL;DR: This medicated diet may be suitable for treating spiral bacteria and Chlamydophila psittaci infections in cockatiels that will consume a pelleted diet. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Inhalation dosimetry of hexamethylene diisocyanate vapor in the rat and human respiratory tracts

INHALATION TOXICOLOGY, 25(3), 168–177.

By: J. Schroeter*, J. Kimbell*, B. Asgharian*, E. Tewksbury*, M. Sochaski*, M. Foster n, D. Dorman n, B. Wong*, M. Andersen*

author keywords: Computational fluid dynamics; dosimetry; hexamethylene diisocyanate; inhalation; lung; nose
MeSH headings : Air Pollutants, Occupational / pharmacokinetics; Air Pollutants, Occupational / toxicity; Animals; Cyanates / pharmacokinetics; Cyanates / toxicity; Dose-Response Relationship, Drug; Humans; Inhalation Exposure; Isocyanates; Lung / drug effects; Lung / metabolism; Lung / pathology; Male; Models, Biological; Rats; Rats, Inbred F344; Respiratory Mucosa / drug effects; Respiratory Mucosa / metabolism; Species Specificity; Volatilization
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Subject Matter Expert and Public Evaluations of a Veterinary Toxicology Course Brochure-Writing Assignment

JOURNAL OF VETERINARY MEDICAL EDUCATION, 40(1), 19–28.

author keywords: communication; brochure; rubrics; toxicology; activity; educational
MeSH headings : Comprehension; Education, Veterinary; Health Communication; North Carolina; Pamphlets; Schools, Veterinary; Students, Health Occupations; Toxicology / education; Writing
TL;DR: How patient-centered written communication has been integrated into the training of veterinary students using toxicology-related preventive materials is described and revised, resulting in revision of the grading rubric, increased use of brochure examples, and additional instruction in readability assessment and brochure development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Skp2 Deficiency Inhibits Chemical Skin Tumorigenesis Independent of p27(Kip1) Accumulation

AMERICAN JOURNAL OF PATHOLOGY, 182(5), 1854–1864.

MeSH headings : Animals; Apoptosis; Carcinogenesis / metabolism; Carcinogenesis / pathology; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p27 / metabolism; Epidermis / metabolism; Epidermis / pathology; Gene Deletion; Humans; Kinetics; Mice; Mice, Inbred C57BL; Papilloma / metabolism; Papilloma / pathology; S-Phase Kinase-Associated Proteins / metabolism; Skin Neoplasms / metabolism; Skin Neoplasms / pathology; Tumor Suppressor Protein p53 / deficiency; Tumor Suppressor Protein p53 / metabolism
TL;DR: It is concluded that p27(Kip1) accumulation is responsible for the hypoplasia observed in normal tissues of Skp2(-/-) mice but does not have a preponderant function in reducing skin tumorigenesis. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Early Weaning Stress in Pigs Impairs Innate Mucosal Immune Responses to Enterotoxigenic E. coli Challenge and Exacerbates Intestinal Injury and Clinical Disease

PLOS ONE, 8(4).

By: B. McLamb n, A. Gibson n, E. Overman n, C. Stahl n & A. Moeser n

MeSH headings : Animals; Animals, Newborn; Cytokines / immunology; Cytokines / metabolism; Dextrans / metabolism; Enterotoxigenic Escherichia coli / immunology; Enterotoxigenic Escherichia coli / pathogenicity; Escherichia coli Infections / veterinary; Ileum / immunology; Ileum / metabolism; Ileum / microbiology; Ileum / pathology; Immunity, Innate; Immunity, Mucosal; Inflammation Mediators / immunology; Inflammation Mediators / metabolism; Intestinal Mucosa / immunology; Intestinal Mucosa / microbiology; Intestinal Mucosa / pathology; Mast Cells / immunology; Mast Cells / pathology; Neutrophils / immunology; Neutrophils / pathology; Permeability; Stress, Physiological / immunology; Swine; Swine Diseases / immunology; Weaning
TL;DR: The early weaning stress can profoundly alter subsequent immune and physiology responses and clinical outcomes to subsequent infectious pathogen challenge, as demonstrated in pigs weaned from their dam. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Developmental origins of a novel gut morphology in frogs

EVOLUTION & DEVELOPMENT, 15(3), 213–223.

By: S. Bloom n, C. Ledon-Rettig n, C. Infante*, A. Everly*, J. Hanken & N. Nascone-Yoder n

MeSH headings : Animals; Anura / embryology; Cell Lineage; Evolution, Molecular; Genetic Variation; Intestines / embryology; Morphogenesis; Phenotype; Phylogeny; Signal Transduction; Species Specificity; Thyroid Hormones / metabolism; Tretinoin / metabolism; Xenopus laevis / embryology
TL;DR: The ancestral gut phenotype in Lepidobatrachus was recovered by performing a reverse chemical manipulation to upregulate RA signaling, providing strong evidence that modifications to this specific pathway promoted the emergence of a lineage‐specific phenotypic novelty. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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