College of Veterinary Medicine - General

Works Published in 2016

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Displaying works 1 - 20 of 23 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 chapter

Genetics of Feline Heart Disease

In August's Consultations in Feline Internal Medicine (Vol. 7, pp. 412–416).

By: K. Meurs*

Sources: Crossref, NC State University Libraries
Added: September 2, 2022

2016 journal article

Evaluation of artificial selection in Standard Poodles using whole-genome sequencing

Mammalian Genome, 27(11-12), 599–609.

MeSH headings : Animals; Breeding; Dogs; Genome / genetics; High-Throughput Nucleotide Sequencing; Homozygote; Integrin alpha2 / genetics; Phenotype; Polycomb-Group Proteins / genetics; Polymorphism, Single Nucleotide / genetics; Selection, Genetic; Tenascin / genetics
TL;DR: This study validated variants related to hair coat and skull morphology that have previously been identified as being under selective pressure in Poodles, and flagged additional polymorphisms in genes such as ITGA2B, CBX4, and TNXB that may represent strong candidates for other common Poodle disorders. (via Semantic Scholar)
Source: Crossref
Added: February 5, 2020

2016 journal article

Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing

Mammalian Genome, 28(1-2), 56–65.

MeSH headings : Addison Disease / genetics; Addison Disease / pathology; Animals; Dog Diseases / genetics; Dogs; Genome-Wide Association Study; Genotyping Techniques; Humans; Hypoadrenocorticism, Familial / genetics; Hypoadrenocorticism, Familial / pathology; Polymorphism, Single Nucleotide; Whole Genome Sequencing / methods
TL;DR: A genome-wide association study of 133 carefully phenotyped Standard Poodles found no markers significantly associated with primary hypoadrenocorticism and identified several candidate genes that may be fixed in both Standard POODles and a small population of dogs of related breeds. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 29, 2019

2016 journal article

Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure

Data in Brief, 6, 989–997.

author keywords: Inhalation; Iron; Manganese; Monkey
TL;DR: Liver manganese and iron levels were linearly correlated although only the intermediate mangansese exposure level (0.3 mg Mn/m3) led to a statistically significant increase in liver iron levels. (via Semantic Scholar)
Source: Crossref
Added: July 21, 2019

2016 journal article

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (118).

By: J. Winston n, R. Thanissery n, S. Montgomery & C. Theriot n

author keywords: Infection; Issue 118; Clostridium difficile; mouse model; antibiotic; colonization; cytotoxicity; histology; inflammation; Vero cells
MeSH headings : Animals; Anti-Bacterial Agents; Cefoperazone / pharmacology; Clostridioides difficile / drug effects; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL
TL;DR: This cefoperazone mouse model of CDI proves a valuable experimental platform to assess the effects of novel therapeutics on the amelioration of clinical disease and on the restoration of colonization resistance against C. difficile. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Effect of feline skin specimen preparation on postexcision and postfixation tissue shrinkage

JOURNAL OF FELINE MEDICINE AND SURGERY, 18(12), 970–975.

MeSH headings : Animals; Cadaver; Cats; Fascia / pathology; Female; Histological Techniques / veterinary; Muscle, Skeletal / pathology; Skin / pathology; Specimen Handling / methods; Specimen Handling / veterinary; Tissue Fixation / veterinary
TL;DR: Surgically obtained feline skin–muscle–fascia specimens will significantly decrease in size prior to formalin fixation, resulting in falsely decreased measurements from tumor to tissue margins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Comparison of hematology, plasma biochemistry, and blood gas variables between 2 venipuncture sites in Southern Stingrays (Dasyatis americana)

Veterinary Clinical Pathology, 45(4), 627–633.

By: B. Phillips n, E. Christiansen n, M. Stoskopf n, H. Broadhurst n, R. George* & C. Harms n

MeSH headings : Animals; Blood Chemical Analysis / veterinary; Female; Hematologic Tests / veterinary; Male; Pathology, Clinical; Phlebotomy / veterinary; Skates, Fish / blood
TL;DR: Good agreement between sampling sites for the majority of the measured analytes and the lack of differences that would alter clinical interpretation support the use of the pectoral site as an alternative to the traditional caudal fin venipuncture site in Southern Stingrays. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science)
Source: NC State University Libraries
Added: August 6, 2018

2016 conference paper

Coalescence prevention algorithm for level set method

Proceedings of the asme fluids engineering division summer meeting, 2016, vol 1b.

By: M. Talley n, M. Zimmer n & I. Bolotnov n

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2016 journal article

Sustained Release of Protein Therapeutics from Subcutaneous Thermosensitive Biocompatible and Biodegradable Pentablock Copolymers (PTSgels)

JOURNAL OF DRUG DELIVERY, 2016.

By: E. Schaefer n, S. Abbaraju*, M. Walsh n, D. Newman n, J. Salmon n, R. Amin*, S. Weiss, U. Grau, P. Velagaleti, B. Gilger n

TL;DR: Subcutaneous PTSgels were highly biocompatible and in vitro IgG release occurred in parallel with the disappearance of subcutaneous gel in vivo, and modulation of release of biologics to fit the therapeutic need can be achieved by varying the biocombatible and biodegradable PTSgel composition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract

ANAEROBE, 41, 44–50.

author keywords: Clostridium difficile; Secondary bile acids; Colonization resistance; Gut microbiota; Antibiotics
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bile Acids and Salts / pharmacology; Bile Acids and Salts / physiology; Clostridioides difficile / drug effects; Clostridioides difficile / physiology; Disease Susceptibility; Drug Resistance, Neoplasm; Enterocolitis, Pseudomembranous / drug therapy; Enterocolitis, Pseudomembranous / microbiology; Gastrointestinal Microbiome; Gastrointestinal Tract / microbiology; Humans
TL;DR: Rational manipulation of secondary bile acids may prove beneficial as a treatment for patients with CDI and shed light on how bile acid play a role in colonization resistance against C. difficile. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Genotype imputation in the domestic dog

MAMMALIAN GENOME, 27(9-10), 485–494.

By: S. Friedenberg n & K. Meurs n

MeSH headings : Alleles; Animals; Breeding; Computer Simulation; Dogs / genetics; Genotype; Models, Genetic; Polymorphism, Single Nucleotide; Sequence Analysis, DNA
TL;DR: These findings demonstrate that genotype imputation from SNP array-derived data to whole genome-level genotypes is both feasible and accurate in the dog with appropriate breed overlap between the target and reference panels. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases)

VETERINARY DERMATOLOGY, 27(6), 488-+.

By: F. Banovic n, K. Linder n, M. Uri n, M. Rossi & T. Olivry n

MeSH headings : Animals; Dog Diseases / pathology; Dogs; Female; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Male; Skin / pathology
TL;DR: Observations support the existence of a canine homologue of human GDLE, a newly recognized canine variant of chronic cutaneous lupus erythematosus that is not well characterized. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy

AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(7), 693–699.

MeSH headings : Animals; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / metabolism; Cardiomyopathy, Dilated / veterinary; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Down-Regulation; Female; Gene Expression; Heart Ventricles; Male; Myocardium / metabolism; RNA / genetics; Up-Regulation
TL;DR: Genes involved in cellular energy metabolism, especially metabolism of carbohydrates and fats, were significantly downregulated in dogs with DCM, and Expression of cardiac structural proteins was also altered in affected dogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

The effect of specimen preparation on post-excision and post-fixation dimensions, translation, and distortion of canine cadaver skin-muscle-fascia specimens

Veterinary Surgery, 45(5), 563–570.

MeSH headings : Animals; Cadaver; Dermatologic Surgical Procedures / veterinary; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Fasciotomy / veterinary; Muscles / surgery; Skin Neoplasms / surgery; Skin Neoplasms / veterinary; Specimen Handling / methods; Specimen Handling / veterinary; Suture Techniques / veterinary
TL;DR: Canine skin-muscle-fascia specimens significantly decrease in size from gross pre-excision dimensions after removal, and Suturing the specimen during surgery before excision will significantly improve alignment of tissue planes without creating distortion of the sample, but may alter the length, width, and lateral margins of the specimen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

The effect of high dose oral manganese exposure on copper, iron and zinc levels in rats

BIOMETALS, 29(3), 417–422.

author keywords: Manganese; Copper; Iron; Zinc; Exposure
MeSH headings : Administration, Oral; Animals; Copper / metabolism; Diet; Homeostasis / drug effects; Iron / metabolism; Male; Manganese / administration & dosage; Manganese / analysis; Manganese / toxicity; Rats; Rats, Inbred F344; Zinc / metabolism
TL;DR: While manganese exposure affected levels of all metals, particularly in the frontal cortex and liver, copper levels were most prominently affected and suggests an under-appreciated effect of manganae exposure on copper homeostasis which may contribute to the understanding of the pathophysiology of mangansese toxicity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Diphenhydramine exposure in dogs: 621 cases (2008-2013)

Journal of the American Veterinary Medical Association, 249(1), 77–82.

By: A. Worth, T. Wismer & D. Dorman*

MeSH headings : Animals; Anti-Allergic Agents / poisoning; Diphenhydramine / poisoning; Dog Diseases / epidemiology; Dog Diseases / pathology; Dog Diseases / prevention & control; Dogs; Female; Illinois / epidemiology; Male; Poison Control Centers / statistics & numerical data; Poisoning / epidemiology; Poisoning / veterinary; Retrospective Studies; Severity of Illness Index
TL;DR: Results indicated that dogs exposed to diphenhydramine developed clinical signs of toxicosis fairly infrequently, and those clinical signs were generally mild and primarily affected the neurologic and cardiovascular systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Cyniclomyces guttulatus Infection in Dogs: 19 Cases (2006-2013)

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 52(1), 42–51.

By: J. Winston n, I. Piperisova n, J. Neel n & J. Gookin n

TL;DR: It is suggested that additional studies to determine if C. guttulatus is a potential cause or consequence of gastrointestinal illness in dogs may be warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Ventricular arrhythmias in Rhodesian Ridgebacks with a family history of sudden death and results of a pedigree analysis for potential inheritance patterns

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 248(10), 1135–1138.

By: K. Meurs n, J. Weidman, S. Rosenthal, K. Lahmers* & S. Friedenberg n

MeSH headings : Animals; Arrhythmias, Cardiac / pathology; Arrhythmias, Cardiac / veterinary; Death, Sudden / veterinary; Dog Diseases; Dogs; Female; Genetic Predisposition to Disease; Male; Pedigree
TL;DR: Holter monitoring of Rhodesian Ridgebacks with a family history of an arrhythmia or sudden death is recommended for early diagnosis of disease and an autosomal recessive pattern of inheritance in the studied dogs was likely, and inbreeding should be strongly discouraged. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Hydrocephalus in three juvenile North American black bears (Ursus americanus)

Journal of Zoo and Wildlife Medicine, 47(2), 632–635.

By: S. Ferguson, J. Novak, S. Hecht & L. Craig

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Exuberant granulation tissue response associated with Neobenedenia sp (Monogenea: Capsalidae) infestation in two cobia, Rachycentron canadum (Linnaeus)

JOURNAL OF FISH DISEASES, 39(3), 277–283.

author keywords: granulation tissue; Neobenedenia; Rachycentron canadum
MeSH headings : Animals; Animals, Zoo / parasitology; Fish Diseases / parasitology; Gills / parasitology; Granulation Tissue / parasitology; Perciformes / parasitology; Trematoda / physiology; Trematode Infections / parasitology; Trematode Infections / veterinary
TL;DR: An unusual pathological presentation of exuberant granulation tissue of the gills, suspected to be related to Neobenedenia infestation in two cobia housed together at a North Carolina aquarium is described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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