College of Veterinary Medicine - General

Works Published in 2002

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Displaying all 12 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2002 journal article

OLFACTORY TRANSPORT: A DIRECT ROUTE OF DELIVERY OF INHALED MANGANESE PHOSPHATE TO THE RAT BRAIN

Journal of Toxicology and Environmental Health, Part A, 65(20), 1493–1511.

By: D. Dorman*, K. Brenneman*, A. McElveen*, S. Lynch*, K. Roberts* & B. Wong*

MeSH headings : Administration, Inhalation; Analysis of Variance; Animals; Autoradiography; Axonal Transport; Brain / metabolism; Linear Models; Male; Manganese / administration & dosage; Manganese / pharmacokinetics; Nasal Mucosa / metabolism; Olfactory Bulb / metabolism; Rats; Spectrometry, Gamma
TL;DR: The results demonstrate that the olfactory route contributes to 54 Mn delivery to the rat Olfactory bulb and tubercle, however, this pathway does not significantly contribute to striatal 54 Mn concentrations following a single, short-term inhalation exposure to54 MnHPO 4. (via Semantic Scholar)
Source: Crossref
Added: February 24, 2020

2002 journal article

Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers

Journal of the American Veterinary Medical Association, 221(4), 522–527.

By: K. Meurs*, A. Spier, N. Wright, C. Atkins, T. DeFrancesco, S. Gordon, R. Hamlin, B. Keene, M. Miller, N. Moise

MeSH headings : Animals; Anti-Arrhythmia Agents / pharmacology; Anti-Arrhythmia Agents / therapeutic use; Arrhythmias, Cardiac / drug therapy; Arrhythmias, Cardiac / veterinary; Atenolol / therapeutic use; Dog Diseases / drug therapy; Dogs; Drug Therapy, Combination; Heart Rate; Mexiletine / therapeutic use; Procainamide / therapeutic use; Random Allocation; Sotalol / therapeutic use; Syncope / drug therapy; Syncope / veterinary; Treatment Outcome; Ventricular Premature Complexes / drug therapy; Ventricular Premature Complexes / veterinary
TL;DR: Significant reductions in number of VPC, severity of arrythmia, and maximum and mean HR were observed in dogs treated with mexiletine-atenolol or sotalol; occurrence of syncope was not significantly different between these 2 treatment groups. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 8, 2020

2002 journal article

Plasma concentrations of tumor necrosis factor-α in cats with congestive heart failure

American Journal of Veterinary Research, 63(5), 640–642.

MeSH headings : Animals; Cardiomyopathy, Dilated / blood; Cardiomyopathy, Dilated / immunology; Cardiomyopathy, Dilated / veterinary; Cat Diseases / blood; Cat Diseases / immunology; Cats; Female; Formazans / chemistry; Male; Mice; Tetrazolium Salts / chemistry; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha / immunology; Tumor Necrosis Factor-alpha / metabolism
TL;DR: Concentrations of TNF-α were increased in 10 of 26 cats with CHF but were undetectable in the other 16 cats withCHF and all control cats, indicating increased cytotoxic effects of T NF-α on L929 murine fibrosarcoma cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 8, 2020

2002 journal article

Preoperative radiotherapy for vaccine associated sarcoma in 92 cats

VETERINARY RADIOLOGY & ULTRASOUND, 43(5), 473–479.

By: T. Kobayashi n, M. Hauck n, R. Dodge*, R. Page*, G. Price, L. Williams n, E. Hardie n, K. Mathews n, D. Thrall n

author keywords: cat; vaccine-associated sarcoma; radiation therapy; preoperative irradiation
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / therapeutic use; Carboplatin / administration & dosage; Carboplatin / therapeutic use; Cat Diseases / chemically induced; Cat Diseases / drug therapy; Cat Diseases / radiotherapy; Cat Diseases / surgery; Cats; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Female; Male; Neoplasm Recurrence, Local / mortality; Neoplasm Recurrence, Local / prevention & control; Neoplasm Recurrence, Local / veterinary; North Carolina; Preoperative Care / veterinary; Records / veterinary; Retrospective Studies; Sarcoma / chemically induced; Sarcoma / mortality; Sarcoma / radiotherapy; Sarcoma / surgery; Sarcoma / veterinary; Soft Tissue Neoplasms / chemically induced; Soft Tissue Neoplasms / mortality; Soft Tissue Neoplasms / radiotherapy; Soft Tissue Neoplasms / surgery; Soft Tissue Neoplasms / veterinary; Treatment Outcome; Vaccination / adverse effects; Vaccination / veterinary
TL;DR: Preoperative irradiation is an effective treatment for cats with vaccine associated sarcoma, especially if complete excision can be accomplished following irradiation, and outcome in cats receiving carboplatin was better than all other treatment groups. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 article

Percutaneous balloon pericardiotomy as a treatment for recurrent pericardial effusion in 6 dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 16, pp. 541–546.

author keywords: cardiac tamponade; chemodectoma; heart base tumor; hemangiosarcoma; idiopathic pericardial effusion
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Effects of long-term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation

Journal of the American Veterinary Medical Association, 221(5), 654–658.

By: C. Atkins n, W. Brown, J. Coats*, M. Crawford, T. DeFrancesco*, J. Edwards, P. Fox, B. Keene* ...

MeSH headings : Angiotensin-Converting Enzyme Inhibitors / adverse effects; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Blood Urea Nitrogen; Creatinine / blood; Dog Diseases / drug therapy; Dogs; Enalapril / adverse effects; Enalapril / therapeutic use; Female; Follow-Up Studies; Kidney / drug effects; Kidney Function Tests / veterinary; Male; Mitral Valve Insufficiency / complications; Mitral Valve Insufficiency / drug therapy; Mitral Valve Insufficiency / veterinary; Time Factors
TL;DR: Results suggest that administration of enalapril for up to 2 years did not have any demonstrable adverse effects on renal function in dogs with severe, compensated mitral regurgitation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2002 journal article

Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain

JOURNAL OF NEUROIMMUNOLOGY, 131(1-2), 135–146.

By: R. Strohmeyer*, M. Ramirez n, G. Cole n, K. Mueller* & J. Rogers*

author keywords: Alzheimer's; factor H; heparan sulfate proteoglycan; agrin; complement receptor 3; amyloid beta
MeSH headings : Aged; Agrin / analysis; Agrin / metabolism; Alzheimer Disease / immunology; Alzheimer Disease / metabolism; Alzheimer Disease / pathology; Amyloid beta-Peptides / analysis; Amyloid beta-Peptides / metabolism; Blotting, Western; Brain / immunology; Brain / metabolism; Brain Chemistry; Complement Factor H / analysis; Complement Factor H / immunology; Complement Factor H / metabolism; Complement Pathway, Alternative; Humans; Immunohistochemistry; Macrophage-1 Antigen / analysis; Neuroglia / immunology
TL;DR: It is proposed that CR3 receptors expressed by microglia are used for ligand binding to factor H bound to HSPGs and Abeta in plaques in the AD brain. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation

AMERICAN JOURNAL OF PATHOLOGY, 161(2), 405–411.

By: M. Rodriguez-Puebla n, P. Marval*, M. LaCava*, D. Moons*, H. Kiyokawa* & C. Conti*

MeSH headings : Animals; Carcinogens / toxicity; Cell Division / genetics; Cell Transformation, Neoplastic / genetics; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases / deficiency; Cyclin-Dependent Kinases / genetics; Keratinocytes / cytology; Keratinocytes / enzymology; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins; Skin Neoplasms / enzymology; Skin Neoplasms / etiology; Skin Neoplasms / genetics; Tetradecanoylphorbol Acetate / toxicity
TL;DR: The results suggest that therapeutic approaches to inhibit cdk4 activity could provide a target to inhibit tumor development with minimal or no effect in normal tissue. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 article

Influence of bolt tightening torque, wire size, and component reuse on wire fixation in circular external fixation

VETERINARY SURGERY, Vol. 31, pp. 571–576.

MeSH headings : Animals; Biomechanical Phenomena; Bone Screws / veterinary; Bone Wires / veterinary; Equipment Failure; Fracture Fixation / methods; Fracture Fixation / veterinary; Orthopedic Fixation Devices / veterinary; Torque
TL;DR: The cannulated and slotted bolts from both manufacturers failed to maintain 70% of initial wire tension after 7 and 4 uses, respectively, and only the IMEX system could maintain clinically recommended wire tension safely using 1.5- or 1.6-mm wires. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Heparin inhibits DNA synthesis and gene expression in alveolar type II cells

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 27(3), 345–352.

MeSH headings : Animals; Cell Division / drug effects; Cells, Cultured; DNA / biosynthesis; DNA / drug effects; Extracellular Matrix / drug effects; Extracellular Matrix / metabolism; Fibroblast Growth Factor 1 / genetics; Fibroblast Growth Factor 1 / metabolism; Fibroblast Growth Factor 1 / pharmacology; Fibroblast Growth Factor 2 / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Heparin / pharmacology; Pulmonary Alveoli / cytology; Pulmonary Alveoli / drug effects; Pulmonary Alveoli / physiology; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases / drug effects; Receptor Protein-Tyrosine Kinases / genetics; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor / drug effects; Receptors, Fibroblast Growth Factor / genetics; Thymidine / metabolism
TL;DR: It is demonstrated that sulfated molecules in the ABM may play important regulatory role(s) in selected type II cell activities during normal cell homeostasis, turnover, and repair after lung injury. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Pharmacokinetics of fluconazole in loggerhead sea turtles (Caretta caretta) after single intravenous and subcutaneous injections, and multiple subcutaneous injections

Journal of Zoo and Wildlife Medicine, 33(1), 29–35.

By: K. Mallo n, C. Harms*, G. Lewbart* & M. Papich*

TL;DR: It is suggested that fluconazole can be effectively administered to sea turtles at a dosage of 10 mg/kg every 5 days after a loading dose of 21mg/kg, and the terminal half-life after the last dose was calculated at 143 hr. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Prostatic pythiosis in a dog

JOURNAL OF VETERINARY INTERNAL MEDICINE, 16(5), 598–602.

Source: Web Of Science
Added: August 6, 2018

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