Works Published in 2005
Displaying works 441 - 460 of 501 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2005 journal article
Asymmetrical protein kinase A activity establishes neutrophil cytoskeletal polarity and enables chemotaxis
JOURNAL OF LEUKOCYTE BIOLOGY, 78(1), 248–258.
author keywords: integrin; adhesion; migration; actin cytoskeleton; phosphatidylinositol-3 kinase
MeSH headings : Actin Cytoskeleton / drug effects; Actin Cytoskeleton / metabolism; CD18 Antigens / metabolism; Cell Adhesion / drug effects; Cell Adhesion / physiology; Cell Polarity / drug effects; Cell Polarity / physiology; Cells, Cultured; Chemotaxis, Leukocyte / drug effects; Chemotaxis, Leukocyte / physiology; Cyclic AMP-Dependent Protein Kinases / antagonists & inhibitors; Cyclic AMP-Dependent Protein Kinases / metabolism; Cytoskeleton / drug effects; Cytoskeleton / enzymology; Dose-Response Relationship, Drug; Enzyme Activation / drug effects; Enzyme Activation / physiology; Enzyme Inhibitors / pharmacology; Humans; Neutrophils / drug effects; Neutrophils / enzymology; Peptides / pharmacology; Phosphatidylinositol 3-Kinases / metabolism; Phosphoinositide-3 Kinase Inhibitors
TL;DR:
The data suggest that asymmetrical PKA activity is necessary and sufficient for actin cytoskeletal polarization and migration during neutrophil chemotaxis, and suggest PI‐3K is an effector of PKA during Chemotaxis.
(via Semantic Scholar)
jlb.onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Whole-blood and plasma cholinesterase levels in normal koi (Cyprinus carpio)
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 17(1), 74–75.
MeSH headings : Acetylcholinesterase / blood; Animals; Carps / blood; Plasma / enzymology; Reference Values
TL;DR:
Results from blood samples from koi suspected to be suffering from anticholinesterase toxicosis may be uninterpretable.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 article
Urinary tract manifestations of protothecosis in dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 19, pp. 115–119.
author keywords: acute renal failure; algae; Prototheca wickerhaniii; Prototheca zopfii; urinary tract infection; urine culture
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Toxicity of novel aromatic and aliphatic organic acid and ester analogs of trypsin modulating oostatic factor to larvae of the northern house mosquito, Culex pipiens complex, and the tobacco hornworm, Manduca sexta
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 81(2), 71–84.
author keywords: trypsin modulating oostatic factor; TMOF; insecticide; mosquito; tobacco hornworm; tobacco budworm; cotton bollworm; German cockroach
TL;DR:
Eight non-peptidic chemical analogs oftrypsin modulating oostatic factor (TMOF, NH2-YDPAP6), an insect hormone inhibiting trypsin biosynthesis in mosquitoes, were synthesized based on the structure of the native peptide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
The origin of stark splitting in the initial photoproduct state of MbCO
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 127(1), 40–41.
MeSH headings : Carbon Monoxide / chemistry; Carbon Monoxide / metabolism; Heme / chemistry; Heme / metabolism; Hydrogen Bonding; Models, Molecular; Myoglobin / chemistry; Myoglobin / metabolism; Photolysis; Spectroscopy, Fourier Transform Infrared
TL;DR:
F Fourier transform infrared (FTIR) spectroscopy and density functional theory (DFT) calculations were used to interpret the effects of the electrostatic environment on the B state bands.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Preclinical Evaluation of a Novel Episcleral Cyclosporine Implant for Ocular Graft-Versus-Host Disease
Investigative Opthalmology & Visual Science, 46(2), 655.
MeSH headings : Animals; Biological Availability; Cyclosporine / pharmacokinetics; Cyclosporine / pharmacology; Cyclosporine / toxicity; Dogs; Drug Evaluation, Preclinical; Drug Implants; Electroretinography / drug effects; Eye / metabolism; Eye / pathology; Female; Graft vs Host Disease / pathology; Graft vs Host Disease / prevention & control; Immunosuppressive Agents / pharmacokinetics; Immunosuppressive Agents / pharmacology; Immunosuppressive Agents / toxicity; Keratoconjunctivitis / drug therapy; Keratoconjunctivitis / pathology; Male; Rabbits; Retina / drug effects; Safety; Sclera / drug effects; Sclera / metabolism; Sclera / pathology
TL;DR:
The episcleral cyclosporine implant shows promise in reducing the morbidity associated with lacrimal gland graft-versus-host disease after allogeneic hematopoietic stem cell transplantation and may have potential in treating other ocular inflammatory diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2005 journal article
Enhanced tumour uptake of radiolabelled antibodies by hyperthermia: Part I: Timing of injection relative to hyperthermia
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 21(1), 1–11.
author keywords: hyperthermia; monoclonal antibody; combined modality therapies; radioimmunotherapy
MeSH headings : Animals; Antibodies, Monoclonal / pharmacokinetics; Antibodies, Neoplasm / pharmacology; Brain Neoplasms / therapy; Cell Line, Tumor; Combined Modality Therapy; Glioma / therapy; Humans; Hyperthermia, Induced / methods; Iodine Radioisotopes / pharmacology; Mice; Mice, Inbred BALB C; Mice, Nude; Radioimmunotherapy / methods; Tenascin / immunology; Xenograft Model Antitumor Assays
TL;DR:
Tumour targeting mAbs administered in combination with heat may be injected either prior to or immediately following hyperthermia treatment, with the expectation that levels of uptake in tumour will be relatively equivalent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Enhanced tumour uptake of radiolabelled antibodies by hyperthermia. Part II: Application of the thermal equivalency equation
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 21(1), 13–27.
author keywords: hyperthermia; monoclonal antibody; thermal isodose; combined modality therapies; radioimmunotherapy
MeSH headings : Animals; Antibodies, Monoclonal / pharmacokinetics; Antibodies, Neoplasm / pharmacology; Brain Neoplasms / therapy; Cell Line, Tumor; Combined Modality Therapy; Glioma / therapy; Humans; Hyperthermia, Induced / methods; Iodine Radioisotopes / pharmacology; Mice; Mice, Inbred BALB C; Mice, Nude; Radiation Dosage; Radioimmunotherapy / methods; Temperature; Xenograft Model Antitumor Assays
TL;DR:
Differences in absolute tumour and normal tissue uptake were seen, suggesting that the thermal isodose formula has limited usefulness in the design and comparison of hyperthermia protocols for enhancing the tumour uptake of radiolabelled mAbs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Canine and feline blood donor screening for infectious disease
JOURNAL OF VETERINARY INTERNAL MEDICINE, 19(1), 135–142.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Treatment of localized lesions of canine atopic dermatitis with tacrolimus ointment: A blinded randomized controlled trial
Veterinary Dermatology, 16(1), 52–60.
Contributors: E. Bensignor & T. Olivry n
MeSH headings : Administration, Topical; Animals; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Double-Blind Method; Female; Immunosuppressive Agents / adverse effects; Immunosuppressive Agents / therapeutic use; Male; Ointments; Severity of Illness Index; Tacrolimus / adverse effects; Tacrolimus / therapeutic use; Treatment Outcome
TL;DR:
Results of this trial suggest that the application of 0.1% tacrolimus ointment is useful for reducing the severity of localized skin lesions of canine AD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Production of germline chimeric chickens following the administration of a busulfan emulsion
MOLECULAR REPRODUCTION AND DEVELOPMENT, 70(4), 438–444.
author keywords: germline; chimera; busulfan; chicken
MeSH headings : Alkylating Agents / pharmacology; Animals; Busulfan / pharmacology; Chick Embryo; Chickens / genetics; Chimera / genetics; Female; Male; Ovum / drug effects; Spermatozoa / drug effects
TL;DR:
Results demonstrated that the administration of a busulfan emulsion into the egg yolk of unincubated eggs improved the depletion of endogenous PGCs in the embryo and enhanced the efficiency of germline chimera production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 article
Nanostructuring polymers with cyclodextrins
POLYMERS FOR ADVANCED TECHNOLOGIES, Vol. 16, pp. 269–275.
author keywords: cyclodextrins; inclusion chemistry; block copolymers; phase separation; nanostructuring
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Junctional epidermolysis bullosa in two domestic shorthair kittens
VETERINARY DERMATOLOGY, 16(1), 69–73.
Contributors: Z. Alhaidari, T. Olivry n , A. Spadafora*, R. Thomas*, C. Perrin *, G. Meneguzzi *, J. Ortonne*
MeSH headings : Animals; Cat Diseases / pathology; Cats; Epidermolysis Bullosa, Junctional / pathology; Epidermolysis Bullosa, Junctional / ultrastructure; Epidermolysis Bullosa, Junctional / veterinary; Female; Fluorescent Antibody Technique, Indirect / veterinary; Immunoenzyme Techniques / veterinary; Laminin / biosynthesis; Male; Microscopy, Electron / veterinary
TL;DR:
This article describes two cases of junctional epidermolysis bullosa in nonrelated kittens, both of which exhibited pinnal erosions, oral ulcerations and severe onychomadesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Evaluation of a method of intracoelomic catheterization in koi
Journal of the American Veterinary Medical Association, 226(5), 784–788.
MeSH headings : Animals; Carps; Catheterization / adverse effects; Catheterization / methods; Catheterization / veterinary; Catheters, Indwelling / adverse effects; Catheters, Indwelling / veterinary; Drug Administration Routes / veterinary; Enrofloxacin; Fluoroquinolones / pharmacokinetics; Prospective Studies; Quinolones / pharmacokinetics; Safety
TL;DR:
An intracoelomic catheter was effective and safe when maintained in koi for at least 6 days and would be highly beneficial for veterinarians, clients, and fish, especially when intracoELomic administration of a drug would require daily or more frequent dosing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2005 journal article
Designing pattern-recognition surfaces for selective adsorption of copolymer sequences using lattice Monte Carlo simulation
PHYSICAL REVIEW LETTERS, 94(7).
MeSH headings : Adsorption; Biocompatible Materials / chemistry; Computer Simulation; Models, Chemical; Molecular Conformation; Monte Carlo Method; Polymers / chemistry; Surface Properties
TL;DR:
A simulation method to design surfaces for recognizing specific monomer sequences in copolymers and finding an optimal surface pattern that can recognize and selectively adsorb the sequence in the copolymer is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(11), 3906–3912.
author keywords: adhesion; stress response; proteolytic system; sugar metabolism; in silico analysis
MeSH headings : Bacterial Adhesion / genetics; Bacteriocins / genetics; Bacteriophages / genetics; Bacteriophages / pathogenicity; Carbohydrate Metabolism; Computational Biology; Genome, Bacterial; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Lactobacillus acidophilus / virology; Molecular Sequence Data; Peptide Hydrolases / genetics; Prophages / genetics; Sequence Analysis, DNA; Transposases / genetics
TL;DR:
These features within the genome sequence of L. acidophilus are likely to contribute to the organisms' gastric survival and promote interactions with the intestinal mucosa and microbiota.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Comparison between two partial likelihood approaches for the competing risks model with missing cause of failure
LIFETIME DATA ANALYSIS, 11(1), 29–40.
author keywords: cause-specific hazard; martingale; missing at random; semiparametric efficiency
MeSH headings : Cause of Death; Humans; Life Tables; Likelihood Functions; Models, Statistical; Proportional Hazards Models; Risk; Risk Assessment; Sensitivity and Specificity; Survival Analysis; United States
TL;DR:
It is shown that the estimator for the regression coefficients based on the Dewanji partial likelihood is not only consistent and asymptotically normal, but also semiparametric efficient.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Bilateral nodular lymphocytic conjunctivitis in a horse
Veterinary Ophthalmology, 8(2), 129–134.
author keywords: conjunctival mass; horse; nodular lymphoid hyperplasia
MeSH headings : Animals; Conjunctival Neoplasms / diagnosis; Conjunctival Neoplasms / veterinary; Diagnosis, Differential; Horse Diseases / diagnosis; Horse Diseases / pathology; Horses; Immunohistochemistry / veterinary; Lymphoma, B-Cell, Marginal Zone / diagnosis; Lymphoma, B-Cell, Marginal Zone / veterinary; Male
TL;DR:
This is the first reported case of bilateral nodular lymphocytic conjunctivitis in a horse and for which surgical excision alone was not curative.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2005 journal article
Bayesian capture-recapture analysis and model selection allowing for heterogeneity and behavioral effects
Journal of Agricultural, Biological, and Environmental Statistics, 10(1), 35–49.
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2005 journal article
An observer study methodology for evaluating detection of motion abnormalities in gated myocardial perfusion SPECT
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 52(3), 480–485.
author keywords: gated SPECT; myocardial SPECT
MeSH headings : Artificial Intelligence; Gated Blood-Pool Imaging / instrumentation; Gated Blood-Pool Imaging / methods; Heart Ventricles / diagnostic imaging; Heart Ventricles / physiopathology; Humans; Image Interpretation, Computer-Assisted / methods; Movement; Observer Variation; Phantoms, Imaging; Reproducibility of Results; Sample Size; Sensitivity and Specificity; Task Performance and Analysis; Tomography, Emission-Computed, Single-Photon / instrumentation; Tomography, Emission-Computed, Single-Photon / methods; Ventricular Dysfunction, Left / diagnostic imaging; Ventricular Dysfunction, Left / physiopathology; Video Recording / methods
TL;DR:
It is concluded that, for the task of detecting abnormal motion, increasing the number of gated frames from 8 to 16 offers no apparent advantage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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