Works Published in 2009

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Displaying works 581 - 600 of 632 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2009 journal article

Regulation of iron metabolism-related genes in diethylnitrosamine-induced mouse liver tumors

TOXICOLOGY LETTERS, 184(3), 151–158.

author keywords: Mouse; Liver tumors; Iron metabolism; Ceruloplasmin; DMT1 IRE(+)
MeSH headings : Adenoma, Liver Cell / chemically induced; Adenoma, Liver Cell / genetics; Adenoma, Liver Cell / metabolism; Animals; Antimicrobial Cationic Peptides / genetics; Antimicrobial Cationic Peptides / metabolism; Cation Transport Proteins / genetics; Cation Transport Proteins / metabolism; Ceruloplasmin / genetics; Ceruloplasmin / metabolism; Copper / metabolism; Diethylnitrosamine; Ferritins / genetics; Ferritins / metabolism; Gene Expression Regulation, Neoplastic; Hepcidins; Immunoblotting; Injections, Subcutaneous; Iron / blood; Iron / metabolism; Iron-Dextran Complex / administration & dosage; Liver Neoplasms, Experimental / chemically induced; Liver Neoplasms, Experimental / genetics; Liver Neoplasms, Experimental / metabolism; Male; Mice; Mice, Inbred C3H; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Transferrin / metabolism
TL;DR: It is suggested that diethylnitrosamine-induced liver adenoma-bearing mice have abnormal iron metabolism and that dysregulation of iron metabolism-related genes contributes to iron deficiency in the adenomas. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Prevalence of Bartonella species antibodies and Bartonella species DNA in the blood of cats with and without fever

Journal of Feline Medicine and Surgery, 11(2), 141–148.

By: M. Lappin*, E. Breitschwerdt n, M. Brewer*, J. Hawley*, B. Hegarty n & S. Radecki*

MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / genetics; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Blotting, Western / standards; Blotting, Western / veterinary; Cat Diseases / blood; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cats; DNA, Bacterial / blood; Enzyme-Linked Immunosorbent Assay / standards; Enzyme-Linked Immunosorbent Assay / veterinary; Fever / blood; Fever / microbiology; Fever / veterinary; Immunodominant Epitopes / immunology; Immunoglobulin G / blood; Polymerase Chain Reaction / standards; Polymerase Chain Reaction / veterinary; Predictive Value of Tests; Prevalence
TL;DR: The results of this study indicate that in cats, Bartonella species antibody tests cannot predict whether fever is due to Bart onella species infection and should not be used to determine the Bartoneella species infection status. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Power and sample size calculation for log-rank test with a time lag in treatment effect

STATISTICS IN MEDICINE, 28(5), 864–879.

By: D. Zhang n & H. Quan*

author keywords: censoring; intent-to-treat analysis; treatment termination
MeSH headings : Algorithms; Cardiovascular Diseases / drug therapy; Clinical Trials as Topic; Computer Simulation; Epidemiologic Research Design; Humans; Proportional Hazards Models; Sample Size; Statistics, Nonparametric; Time Factors; Treatment Outcome
TL;DR: Simulation studies indicate that the formulas necessary to calculate the asymptotic power of the log‐rank test under this non‐proportional hazards alternative for the two data analysis strategies provide accurate power for a variety of trial settings. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Intracranial Abscessation as a Natural Mortality Factor for Adult Male White-Tailed Deer (Odocoileus Virginianus) in Kent County, Maryland, USA

JOURNAL OF WILDLIFE DISEASES, 45(1), 196–200.

By: G. Karns n, R. Lancia n, C. DePerno n, M. Conner* & M. Stoskopf n

author keywords: Arcanobacterium pyogenes; intracranial abscessation; Maryland; Odocoileus virginianus; Texas; white-tailed deer
MeSH headings : Actinomycetales Infections / epidemiology; Actinomycetales Infections / mortality; Actinomycetales Infections / veterinary; Age Factors; Animals; Animals, Wild / microbiology; Arcanobacterium / isolation & purification; Brain Abscess / epidemiology; Brain Abscess / microbiology; Brain Abscess / mortality; Brain Abscess / veterinary; Cause of Death; Deer / microbiology; Male; Maryland / epidemiology; Prevalence; Sex Factors; Texas / epidemiology
TL;DR: The rate of intracranial abscess among adult male white-tailed deer at the Maryland, USA, site (35%) exceeds reported rates for other regions of the United States (9%). (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Epidermal Growth Factor-Induced Proliferation of Chicken Primordial Germ Cells: Involvement of Calcium/Protein Kinase C and NFKB1

BIOLOGY OF REPRODUCTION, 80(3), 528–536.

author keywords: apoptosis; Ca2+/PKC; embryo; epidermal growth factor; NFKB1; polypeptide receptors; primordial germ cell; proliferation; signal transduction
MeSH headings : Animals; Apoptosis / physiology; Calcium / metabolism; Caspase 3 / metabolism; Caspase 9 / metabolism; Cell Proliferation / drug effects; Cells, Cultured; Chick Embryo; Cyclin D1 / metabolism; Cyclin-Dependent Kinase 2 / metabolism; Dose-Response Relationship, Drug; Epidermal Growth Factor / pharmacology; ErbB Receptors / metabolism; Germ Cells / cytology; Germ Cells / drug effects; NF-kappa B p50 Subunit / metabolism; Protein Kinase C / metabolism; Signal Transduction / physiology; bcl-2-Associated X Protein / metabolism
TL;DR: Observations suggest that EGF signaling is important in regulating germ cell proliferation in the chicken embryonic gonad through activation of Ca2+/PKC involving NFKB1 signaling pathway. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Antinociceptive and side-effects of hydromorphone after subcutaneous administration in cats

JOURNAL OF FELINE MEDICINE AND SURGERY, 11(2), 76–81.

MeSH headings : Analgesics, Opioid / administration & dosage; Analgesics, Opioid / adverse effects; Analgesics, Opioid / pharmacology; Animals; Cat Diseases / chemically induced; Cats / metabolism; Female; Hydromorphone / administration & dosage; Hydromorphone / adverse effects; Hydromorphone / pharmacology; Injections, Subcutaneous / veterinary; Male; Sialorrhea / chemically induced; Sialorrhea / veterinary; Skin Temperature / drug effects; Time Factors; Vomiting / chemically induced; Vomiting / veterinary
TL;DR: Compared to previously published studies of IV and IM administration of hydromorphone, the SC route results in a slower onset of peak effect, a shorter duration of antinociception and is associated with more undesirable side-effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Absolute Quantification of C-Reactive Protein in Human Plasma Derived from Patients with Epithelial Ovarian Cancer Utilizing Protein Cleavage Isotope Dilution Mass Spectrometry

JOURNAL OF PROTEOME RESEARCH, 8(2), 1085–1090.

By: D. Williams n & D. Muddiman n

author keywords: absolute quantification; C-reactive protein; ovarian cancer; single reaction monitoring
MeSH headings : Amino Acid Sequence; C-Reactive Protein / chemistry; C-Reactive Protein / metabolism; Chromatography, Liquid / methods; Female; Humans; Isotope Labeling / methods; Mass Spectrometry / methods; Molecular Sequence Data; Ovarian Neoplasms / blood; Ovarian Neoplasms / chemistry; Peptides / chemistry; Peptides / genetics; Peptides / metabolism; Reproducibility of Results
TL;DR: Interestingly, the PC-IDMS method provided concentration values that were approximately 10x the concentration reported by the ELISA method, which demonstrated that the method of detection is an important consideration when determining reference ranges of a particular analyte. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Spin-Labeled pH-Sensitive Phospholipids for Interfacial pK(a) Determination: Synthesis and Characterization in Aqueous and Micellar Solutions

JOURNAL OF PHYSICAL CHEMISTRY B, 113(11), 3453–3460.

Contributors: M. Voinov n, I. Kirilyuk n & A. Smirnov n

MeSH headings : Electrochemistry; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Mercaptoethanol / chemistry; Micelles; Models, Molecular; Nitrogen / chemistry; Phospholipids / chemistry; Solutions; Spin Labels; Water
TL;DR: The synthesis and characterization of spin-labeled phospholipids with pH-reporting nitroxides that are covalently attached to the lipid's polar headgroup are being reported, indicating that in mixed aqueous/organic solvents, the amphiphilic lipid molecules could be shielded from changing bulk conditions by a local shell of solvent molecules. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Solution-State Conformational Ensemble of a Hexameric Porphyrin Array Characterized Using Molecular Dynamics and X-ray Scattering

JOURNAL OF PHYSICAL CHEMISTRY A, 113(11), 2516–2523.

MeSH headings : Computer Simulation; Macromolecular Substances / chemistry; Motion; Porphyrins / chemistry; Solutions; Thermodynamics; Toluene; X-Ray Diffraction
TL;DR: Comparison between experiment and simulation provides a means not only to interpret scattering data in terms of an explicit atomic model but more generally demonstrates the use of solution X-ray scattering as an experimental benchmark for the development of simulation methods that more accurately predict configurational dynamics of supramolecular assemblies. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Porous Nylon-6 Fibers via a Novel Salt-Induced Electrospinning Method

MACROMOLECULES, 42(3), 709–715.

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Mesenchymal stem cell-seeded collagen matrices for bone repair: Effects of cyclic tensile strain, cell density, and media conditions on matrix contraction in vitro

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 88A(3), 778–786.

author keywords: bone tissue engineering; mechanical stimulation; osteogenic differentiation; collagen contraction; mesenchymal stem cells
MeSH headings : Adult; Bone and Bones / cytology; Cell Culture Techniques / methods; Cell Differentiation; Cell Survival; Collagen; Culture Media, Conditioned; Humans; Male; Mesenchymal Stem Cells / cytology; Tensile Strength
TL;DR: Findings suggest a correlation between hMSC proliferation and osteogenic differentiation on collagen matrix contraction that is affected by media, cell-seeding density, and cyclic tensile strain. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Lifespan changes in working memory in fragile X premutation males

BRAIN AND COGNITION, 69(3), 551–558.

author keywords: Fragile X syndrome; Fragile X tremor and ataxia syndrome; Premutation status; Working memory; Central executive; Phonological loop; Visual-spatial sketchpad; Development; Aging
MeSH headings : Adolescent; Adult; Aged; Aging; Fragile X Mental Retardation Protein / genetics; Fragile X Syndrome / genetics; Heterozygote; Humans; Intelligence Tests; Linear Models; Male; Memory, Short-Term / physiology; Middle Aged; Neuropsychological Tests; Principal Component Analysis; Surveys and Questionnaires; Trinucleotide Repeat Expansion; Young Adult
TL;DR: The findings indicate a specific vulnerability in premutation males on tasks that require simultaneous manipulation and storage of new information, so-called executive control of memory, which appears to exist regardless of the presence of FXTAS symptoms. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Development of a nanoLC LTQ Orbitrap Mass Spectrometric Method for Profiling Glycans Derived from Plasma from Healthy, Benign Tumor Control, and Epithelial Ovarian Cancer Patients

ANALYTICAL CHEMISTRY, 81(3), 1130–1136.

By: M. Bereman n, T. Williams n & D. Muddiman n

MeSH headings : Biomarkers, Tumor / blood; Biomarkers, Tumor / chemistry; Carcinoma / diagnosis; Chromatography, Liquid / methods; Female; Genital Neoplasms, Female / chemistry; Genital Neoplasms, Female / diagnosis; Glycoproteins / blood; Glycoproteins / chemistry; Humans; Hydrophobic and Hydrophilic Interactions; Lectins / blood; Lectins / chemistry; Male; Ovarian Neoplasms / diagnosis; Polysaccharides / blood; Polysaccharides / chemistry; ROC Curve; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: A split-less nano-flow liquid chromatography mass spectrometric analysis of glycans chemically cleaved from glycoproteins in plasma shows similar column efficiencies and excellent retention time reproducibility without an internal standard to correct for retention time shift. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Climatic drivers of hemispheric asymmetry in global patterns of ant species richness

ECOLOGY LETTERS, 12(4), 324–333.

author keywords: Biodiversity; climate change; Eocene; Formicidae; latitudinal gradient
MeSH headings : Animals; Ants / genetics; Ants / physiology; Biodiversity; Biological Evolution; Climate
TL;DR: Examining the latitudinal pattern of species richness across 1003 local ant assemblages finds latitudinal asymmetry, with southern hemisphere sites being more diverse than northern hemisphere sites, and the most parsimonious explanation is that greater climate change since the Eocene in the northern than in the southern hemisphere has led to more extinctions in the north with consequent effects on local ant species richness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Characterization of Dehaloperoxidase Compound ES and Its Reactivity with Trihalophenols†

Biochemistry, 48(5), 995–1005.

By: J. Feducia n, R. Dumarieh n, L. Gilvey n, T. Smirnova n, S. Franzen n & R. Ghiladi n

Contributors: J. Feducia n, R. Dumarieh n, L. Gilvey n, T. Smirnova n, S. Franzen n & R. Ghiladi n

MeSH headings : Animals; Binding Sites; Chlorophenols / chemistry; Chlorophenols / metabolism; Crystallography, X-Ray; Cytochrome-c Peroxidase / chemistry; Cytochrome-c Peroxidase / metabolism; Electron Transport Complex IV / chemistry; Electron Transport Complex IV / metabolism; Hemoglobins / chemistry; Hemoglobins / metabolism; Peroxidases / chemistry; Peroxidases / metabolism; Polychaeta / enzymology
TL;DR: It is demonstrated that the first detectable intermediate following the addition of hydrogen peroxide to ferric DHP contains both a ferryl heme and a tyrosyl radical, analogous to Compound ES of cytochrome c peroxidase. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Aquatic animal models of human disease: Selected papers and recommendations from the 4th Conference

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 149(2), 121–128.

By: D. Hinton*, R. Hardman*, S. Kullman n, J. Law n, M. Schmale*, R. Walter*, R. Winn*, J. Yoder n

MeSH headings : Animals; Disease Models, Animal; Fishes; Humans; Mollusca
TL;DR: Of increasing importance are contributions of aquatic invertebrates and fishes to the detection of toxic responses from: metal mining and smelting impacts, polycyclic aromatichydrocarbons and persistent organic pollutants and their adverse effects in harbors and coastal estuaries, including the verification of remediation processes. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Altered bone marrow dendritic cell cytokine production to toll-like receptor and CD40 ligation during chronic feline immunodeficiency virus infection

IMMUNOLOGY, 126(3), 405–412.

By: T. Lehman*, . Kevin P. O'Halloran*, S. Fallon*, L. Habermann*, J. Campbell*, S. Nordone n, G. Dean n, E. Hoover*, P. Avery*

author keywords: cell surface molecules; cytokines; dendritic cells; immunodeficiency diseases; other animals
MeSH headings : Animals; Bone Marrow Cells / immunology; CD40 Ligand / immunology; Cats; Chronic Disease; Cytokines / biosynthesis; Dendritic Cells / immunology; Feline Acquired Immunodeficiency Syndrome / immunology; Gene Expression; Immunodeficiency Virus, Feline; Interleukin-10 / biosynthesis; Interleukin-12 / biosynthesis; RNA, Messenger / genetics; Toll-Like Receptors / biosynthesis; Toll-Like Receptors / genetics; Toll-Like Receptors / immunology
TL;DR: Chronic FIV infection alters the ratio of immunoregulatory cytokines produced by BM‐DCs in response to certain pathogen‐derived signals, which is probably relevant to the increased risk of opportunistic infections seen in lentiviral infection. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Surgical correction of severe strabismus and enophthalmos secondary to zygomatic arch fracture in a dog

Veterinary Ophthalmology, 12(2), 119–124.

author keywords: dog; fracture; miniplate fixation; orbital rim
MeSH headings : Animals; Bone Plates / veterinary; Dog Diseases / surgery; Dogs; Enophthalmos / surgery; Enophthalmos / veterinary; Male; Strabismus / surgery; Strabismus / veterinary; Zygomatic Fractures / surgery; Zygomatic Fractures / veterinary
TL;DR: A grossly displaced segmental zygomatic arch fracture with marked ventro-lateral deviation of the left globe was diagnosed in a 3-month-old male German Shepherd dog following a bite injury and surgical correction achieved sufficient skeletal fixation for proper anatomical reduction of the globe. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2009 journal article

Shrinkage inverse regression estimation for model-free variable selection

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY, 71, 287–299.

By: H. Bondell n & L. Li n

author keywords: Inverse regression estimation; Non-negative garrotte; Sliced inverse regression; Sufficient dimension reduction; Variable selection
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Safety and Immunogenicity of the Mycobacterium tuberculosis Delta lysA Delta panCD Vaccine in Domestic Cats Infected with Feline Immunodeficiency Virus

CLINICAL AND VACCINE IMMUNOLOGY, 16(3), 427–429.

By: D. Zimmerman*, W. Waters*, K. Lyashchenko*, B. Nonnecke*, D. Armstrong*, W. Jacobs n, M. Larsen n, E. Egan*, G. Dean*

MeSH headings : Animals; Antibodies, Bacterial / blood; Cats; Feline Acquired Immunodeficiency Syndrome / immunology; Hypersensitivity, Delayed; Tuberculosis Vaccines / adverse effects; Tuberculosis Vaccines / immunology
TL;DR: Feline immunodeficiency virus (FIV)-positive and FIV-negative cats received 2 × 106 CFU Mycobacterium tuberculosis ΔlysA ΔpanCD intramuscularly and elicited antibody responses, albeit at lower levels in Fiv-positive cats than in FIV -negative cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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