Works (46)

Updated: March 2nd, 2024 18:42

2023 article

Characterization and biological evaluation of a novel flavonoid-collagen antioxidant hydrogel with cytoprotective properties

Nalband, D. M., Sarker, P., Khan, S. A., & Freytes, D. O. (2023, September 16). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol. 9.

By: D. Nalband n, P. Sarker n, S. Khan n & D. Freytes n

co-author countries: United States of America 🇺🇸
author keywords: antioxidant; collagen; hydrogel; luteolin; reactive oxygen species; skin graft; wound healing
Sources: Web Of Science, ORCID
Added: October 23, 2023

2023 journal article

Scalable and High-Throughput In Vitro Vibratory Platform for Vocal Fold Tissue Engineering Applications

BIOENGINEERING-BASEL, 10(5).

By: A. Biehl n, R. Colmon n, A. Timofeeva n, A. Gracioso Martins n, G. Dion*, K. Peters n, D. Freytes n

co-author countries: United States of America 🇺🇸
author keywords: vocal fold; bioreactor; piezoelectric speaker; vibration; frequency; displacement; fibroblasts; mesenchymal stem cells; gene expression
Sources: Web Of Science, ORCID
Added: May 22, 2023

2023 journal article

Tendon Extracellular Matrix Promotes Myotendinous Junction Protein Expression in Engineered Muscle Tissue under Both Static and Mechanically Stimulated Culture Conditions

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2023.

By: L. Gaffney n, M. Fisher n & D. Freytes n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: September 18, 2023

2022 journal article

Bioreactors for Vocal Fold Tissue Engineering

TISSUE ENGINEERING PART B-REVIEWS, 28(1), 182–205.

By: A. Gracioso Martins n, A. Biehl n, D. Sze n & D. Freytes n

co-author countries: United States of America 🇺🇸
author keywords: vocal fold; bioreactor; lamina propria; gene expression; fibrosis; inflammation
MeSH headings : Biocompatible Materials; Bioreactors; Cicatrix; Humans; Tissue Engineering / methods; Vocal Cords / pathology; Vocal Cords / physiology
Source: Web Of Science
Added: March 29, 2021

2022 article

Donor Age and Time in Culture Affect Dermal Fibroblast Contraction in an In Vitro Hydrogel Model

Detwiler, A., Polkoff, K., Gaffney, L., Freytes, D. O., & Piedrahita, J. A. (2022, August 4). TISSUE ENGINEERING PART A.

By: A. Detwiler n, K. Polkoff n, L. Gaffney n, D. Freytes n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: cell proliferation; collagen; dermis; extracellular matrix; fibroblasts; hydrogels; skin; wound healing
MeSH headings : Adult; Infant, Newborn; Humans; Swine; Animals; Hydrogels / pharmacology; Reproducibility of Results; Wound Healing; Collagen / chemistry; Fibroblasts
Source: Web Of Science
Added: August 29, 2022

2022 article

High-Axial-Aspect Tannic Acid Microparticles Facilitate Gelation and Injectability of Collagen-Based Hydrogels

Sarker, P., Nalband, D. M., Freytes, D. O., Rojas, O. J., & Khan, S. A. (2022, October 5). BIOMACROMOLECULES, Vol. 10.

By: P. Sarker n, D. Nalband n, D. Freytes n, O. Rojas n & S. Khan n

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
MeSH headings : Humans; Hydrogels / chemistry; Tannins; Collagen / chemistry; Elastic Modulus; Rheology
Sources: Web Of Science, ORCID
Added: October 6, 2022

2022 journal article

Monitoring decellularization via absorbance spectroscopy during the derivation of extracellular matrix scaffolds

BIOMEDICAL MATERIALS, 17(1).

co-author countries: Puerto Rico 🇵🇷 United States of America 🇺🇸
author keywords: extracellular matrix; manufacturing; decellularization; monitoring; vocal fold
MeSH headings : Biocompatible Materials; Extracellular Matrix / chemistry; Hydrogels; Regenerative Medicine; Spectrum Analysis; Tissue Engineering / methods; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: November 4, 2021

2022 article

Towards a standardized multi-tissue decellularization protocol for the derivation of extracellular matrix materials

Biehl, A., Martins, A. M. G. M., Davis, Z. G. G., Sze, D., Collins, L., Mora-Navarro, C., … Freytes, D. O. O. (2022, December 12). BIOMATERIALS SCIENCE, Vol. 12.

co-author countries: Puerto Rico 🇵🇷 United States of America 🇺🇸
MeSH headings : Tissue Engineering / methods; Proteomics; Extracellular Matrix / chemistry; Hydrogels / chemistry; Biocompatible Materials / analysis; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: January 3, 2023

2021 journal article

Dermal Extracellular Matrix-Derived Hydrogels as an In Vitro Substrate to Study Mast Cell Maturation

TISSUE ENGINEERING PART A, 27(15-16), 1008–1022.

By: E. Ozpinar n, A. Frey n, G. Arthur n, C. Mora-Navarro n, A. Biehl n, D. Snider n, G. Cruse n, D. Freytes n

co-author countries: United States of America 🇺🇸
author keywords: extracellular matrix; mast cell; allergy; metabolism
MeSH headings : Animals; Cell Differentiation; Collagen; Extracellular Matrix; Humans; Hydrogels; Mast Cells; Swine
Sources: Web Of Science, ORCID
Added: December 11, 2020

2021 article

Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins

Gaffney, L. S., Davis, Z. G., Mora-Navarro, C., Fisher, M. B., & Freytes, D. O. (2021, November 2). TISSUE ENGINEERING PART A, Vol. 11.

By: L. Gaffney n, Z. Davis n, C. Mora-Navarro n, M. Fisher n & D. Freytes n

co-author countries: United States of America 🇺🇸
author keywords: extracellular matrix; engineered tissues; myotendinous junction; paxillin
MeSH headings : Collagen / metabolism; Collagen Type I / metabolism; Culture Media, Conditioned; Extracellular Matrix / metabolism; Hydrogels; Muscles; Paxillin / metabolism; Tendons / metabolism
Sources: Web Of Science, ORCID
Added: November 15, 2021

2021 journal article

Mast Cell-Biomaterial Interactions and Tissue Repair

TISSUE ENGINEERING PART B-REVIEWS, 27(6), 590–603.

By: E. Ozpinar n, A. Frey n, G. Cruse n & D. Freytes n

co-author countries: United States of America 🇺🇸
author keywords: mast cells; biomaterials; inflammation; tissue repair; foreign body response; wound healing
MeSH headings : Biocompatible Materials; Cell Communication; Fibrosis; Humans; Mast Cells / pathology; Tissue Engineering
Sources: Web Of Science, ORCID
Added: March 8, 2021

2021 journal article

Microphysiological System for High-Throughput Computer Vision Measurement of Microtissue Contraction

ACS SENSORS, 6(3), 985–994.

co-author countries: United States of America 🇺🇸
author keywords: high throughput; 3D culture; tissue function; tissue contraction; computer vision
MeSH headings : Computers; Fibroblasts; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted
Source: Web Of Science
Added: May 10, 2021

2021 journal article

Transcriptome-targeted analysis of human peripheral blood-derived macrophages when cultured on biomaterial meshes

BIOMEDICAL MATERIALS, 16(2).

By: C. Mora-Navarro n, E. Ozpinar n, D. Sze n, D. Martin* & D. Freytes n

co-author countries: United States of America 🇺🇸
author keywords: surgical meshes; macrophage polarization; biomaterials; targeted transcriptome; poly-4-hydroxybutyrate (P4HB); polypropylene
MeSH headings : Anti-Inflammatory Agents / chemistry; Biocompatible Materials / chemistry; Cell Culture Techniques; Cell Differentiation; Cell Separation; Cells, Cultured; Flow Cytometry; Gene Expression Profiling; Humans; Hydroxybutyrates; Immunity, Innate; In Vitro Techniques; Inflammation; Macrophages / drug effects; Macrophages / metabolism; Materials Testing; Monocytes / cytology; Phenotype; Polypropylenes / chemistry; Prostheses and Implants; RNA / metabolism; Surgical Mesh; Tissue Scaffolds; Transcriptome; Treatment Outcome; Up-Regulation; Wound Healing
Sources: Web Of Science, ORCID
Added: January 16, 2021

2020 journal article

Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides

JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413–7427.

By: K. Day n, J. Schneible n, A. Young n, V. Pozdin*, G. Driessche n, L. Gaffney n, R. Prodromou n, D. Freytes n ...

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Azo Compounds / chemistry; Hydrogen-Ion Concentration; Isomerism; Osmolar Concentration; Peptides, Cyclic / chemistry; Photochemical Processes
Sources: Web Of Science, ORCID
Added: September 14, 2020

2020 journal article

Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 577, 406–418.

By: S. Nandi n, L. Sommerville*, K. Nellenbach n, E. Mihalko n, M. Erb n, D. Freytes n, M. Hoffman*, D. Monroe*, A. Brown n

co-author countries: United States of America 🇺🇸
author keywords: Fibrin; Biomimetic; Platelet; Hemophilia; Biomaterials
MeSH headings : Blood Coagulation; Blood Platelets; Fibrin; Plasma; Wound Healing
Source: Web Of Science
Added: August 24, 2020

2019 journal article

Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes

BIOMATERIALS SCIENCE, 7(2), 669–682.

By: S. Nandi n, E. Sproul n, K. Nellenbach n, M. Erb n, L. Gaffney n, D. Freytes n, A. Brown n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Biomimetic Materials / chemistry; Blood Platelets / metabolism; Blood Platelets / physiology; Fibrin / chemistry; Fibrin / pharmacology; Humans; Mechanical Phenomena; Mice; Platelet Activation / drug effects; Skin / drug effects; Skin / injuries; Wound Healing / drug effects
Source: Web Of Science
Added: February 18, 2019

2018 journal article

Enhanced tissue remodelling efficacy of adipose-derived mesenchymal stem cells using injectable matrices in radiation-damaged salivary gland model

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 12(2), E695–E706.

By: J. Choi, H. An, H. Shin, Y. Kim & J. Lim

co-author countries: United States of America 🇺🇸
author keywords: salivary gland; adipose tissue-derived mesenchymal stem cells; small intestinal submucosa gel; radiation; regeneration; local transplantation
MeSH headings : Bone Morphogenetic Proteins / pharmacology; Embryonic Stem Cells / cytology; Embryonic Stem Cells / drug effects; Gene Expression Regulation / drug effects; Heart, Artificial; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Imaging, Three-Dimensional; Models, Biological; Myocardium / pathology; Neovascularization, Physiologic / drug effects; Wound Healing / drug effects
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure

ACS Nano, 12(7), 6536–6544.

By: H. Liang n, K. Huang n, T. Su n, Z. Li n, S. Hu n, P. Dinh n, E. Wrona n, C. Shao* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸

Contributors: H. Liang n, K. Huang n, T. Su n, Z. Li n, S. Hu n, P. Dinh n, E. Wrona n, C. Shao* ...

author keywords: mesenchymal stem cells; red blood cells; biomimetic; nanoparticles; membrane cloaking; liver failure
MeSH headings : Animals; Apoptosis; Biomimetic Materials / chemistry; Biomimetic Materials / therapeutic use; Carbon Tetrachloride; Cell Line; Cell Proliferation; Disease Models, Animal; Erythrocyte Membrane / chemistry; Humans; Liver Failure, Acute / chemically induced; Liver Failure, Acute / pathology; Liver Failure, Acute / physiopathology; Liver Failure, Acute / therapy; Liver Regeneration; Male; Mesenchymal Stem Cells / chemistry; Mice; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / therapeutic use
Sources: Crossref, ORCID
Added: September 10, 2019

2018 review

Potential Synergistic Effects of Stem Cells and Extracellular Matrix Scaffolds

[Review of ]. ACS BIOMATERIALS SCIENCE & ENGINEERING, 4(4), 1208–1222.

By: L. Gaffney n, E. Wrona n & D. Freytes n

co-author countries: United States of America 🇺🇸

Contributors: L. Gaffney n, E. Wrona n & D. Freytes n

author keywords: extracellular matrix (ECM); stem cells; pluripotent stem cells (PSCs); wound healing; macrophage polarization
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

BMP protein-mediated crosstalk between inflammatory cells and human pluripotent stem cell-derived cardiomyocytes

Journal of Tissue Engineering and Regenerative Medicine, 11(5), 1466–1478.

By: I. Pallotta*, B. Sun*, E. Wrona* & D. Freytes*

co-author countries: United States of America 🇺🇸

Contributors: I. Pallotta*, B. Sun*, E. Wrona* & D. Freytes*

author keywords: cardiomyocytes; macrophages; inflammation; BMP; migration; tissue engineering; regenerative medicine
MeSH headings : Bone Morphogenetic Protein 4 / metabolism; Cell Communication; Humans; Inflammation / metabolism; Inflammation / pathology; Macrophages / metabolism; Macrophages / pathology; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Pluripotent Stem Cells / metabolism; Pluripotent Stem Cells / pathology; Smad Proteins / metabolism
Sources: Crossref, ORCID
Added: September 10, 2019

2017 journal article

Directed Differentiation of Human Pluripotent Stem Cells to Microglia

STEM CELL REPORTS, 8(6), 1516–1524.

By: P. Douvaras*, B. Sun*, M. Wang*, I. Kruglikov*, G. Lallos*, M. Zimmer*, C. Terrenoire*, B. Zhang* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Adenosine Diphosphate / pharmacology; CX3C Chemokine Receptor 1 / metabolism; Calcium / metabolism; Cell Differentiation; Cell Line; Cytokines / metabolism; Gene Expression; Human Embryonic Stem Cells / cytology; Human Embryonic Stem Cells / metabolism; Humans; Lipopolysaccharide Receptors / metabolism; Macrophages / cytology; Macrophages / metabolism; Microglia / cytology; Microglia / drug effects; Microglia / metabolism; Pluripotent Stem Cells / cytology; Pluripotent Stem Cells / metabolism
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Macrophages' role in tissue disease and regeneration

Macrophages: Origin, Functions and Biointervention, 62, 245–271.

By: L. Gaffney, P. Warren, E. Wrona, M. Fisher & D. Freytes

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Differential gene expression in human, murine, and cell line-derived macrophages upon polarization

Experimental Cell Research, 347(1), 1–13.

By: K. Spiller*, E. Wrona*, S. Romero-Torres, I. Pallotta*, P. Graney*, C. Witherel*, L. Panicker*, R. Feldman* ...

co-author countries: United States of America 🇺🇸

Contributors: K. Spiller*, E. Wrona*, S. Romero-Torres, I. Pallotta*, P. Graney*, C. Witherel*, L. Panicker*, R. Feldman* ...

author keywords: Classically activated; Alternatively activated macrophages; Wound healing; In vitro characterization; Angiogenesis; Tissue engineering; Induced pluripotent stem cells; Biomaterials
MeSH headings : Animals; Biocompatible Materials / pharmacology; Cell Differentiation / drug effects; Cell Line; Cell Polarity / drug effects; Cell Polarity / genetics; Discriminant Analysis; Gene Expression Profiling; Gene Expression Regulation / drug effects; Humans; Interferon-gamma / pharmacology; Least-Squares Analysis; Lipopolysaccharides / pharmacology; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice, Inbred BALB C; Phenotype
Sources: Crossref, ORCID
Added: September 10, 2019

2016 review

Extracellular Matrix for Vocal Fold Lamina Propria Replacement: A Review

[Review of ]. TISSUE ENGINEERING PART B-REVIEWS, 22(6), 421–429.

By: E. Wrona n, R. Peng*, M. Amin*, R. Branski* & D. Freytes n

co-author countries: United States of America 🇺🇸

Contributors: E. Wrona n, R. Peng*, M. Amin*, R. Branski* & D. Freytes n

author keywords: voice; vocal fold; extracellular matrix; scaffold
MeSH headings : Extracellular Matrix; Humans; Mucous Membrane; Regenerative Medicine; Tissue Engineering; Vocal Cords
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Response of human macrophages to wound matrices in vitro

WOUND REPAIR AND REGENERATION, 24(3), 514–524.

By: C. Witherel*, P. Graney*, D. Freytes n, M. Weingarten* & K. Spiller*

co-author countries: United States of America 🇺🇸
MeSH headings : Acellular Dermis; Biocompatible Materials / pharmacology; Biological Dressings; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Cellular Microenvironment / drug effects; Cellular Microenvironment / physiology; Humans; Macrophages / drug effects; Macrophages / metabolism; Materials Testing; Neovascularization, Physiologic / drug effects; Neovascularization, Physiologic / physiology; Phenotype; Tissue Scaffolds; Wound Healing / drug effects; Wound Healing / physiology
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Controlled release of cytokines using silk-biomaterials for macrophage polarization

Biomaterials, 73, 272–283.

By: A. Reeves*, K. Spiller*, D. Freytes*, G. Vunjak-Novakovic* & D. Kaplan*

co-author countries: United States of America 🇺🇸
author keywords: Macrophage; Polarization; Silk; Cytokine
MeSH headings : Aniline Compounds / chemistry; Animals; Biocompatible Materials / chemistry; Cytokines / metabolism; Delayed-Action Preparations / metabolism; Humans; Interferon-gamma / administration & dosage; Interleukin-4 / administration & dosage; Macrophages / cytology; Macrophages / metabolism; Mice; Microscopy, Electron, Scanning; Phenotype; Protein Structure, Secondary; Real-Time Polymerase Chain Reaction; Silk / chemistry; Solubility; Time Factors; Water / chemistry
Source: Crossref
Added: February 24, 2020

2015 journal article

Derivation and characterization of porcine vocal fold extracellular matrix scaffold

The Laryngoscope, 126(4), 928–935.

By: E. Wrona*, R. Peng*, H. Born*, M. Amin*, R. Branski* & D. Freytes*

co-author countries: United States of America 🇺🇸

Contributors: E. Wrona*, R. Peng*, H. Born*, M. Amin*, R. Branski* & D. Freytes*

author keywords: Vocal fold; extracellular matrix; mesenchymal stem cells; scaffold
MeSH headings : Animals; Cells, Cultured; DNA / analysis; Deoxycholic Acid; Extracellular Matrix / physiology; Gene Expression; Mesenchymal Stem Cells / cytology; Peracetic Acid; Swine; Tissue Engineering / methods; Tissue Scaffolds; Vocal Cords / cytology
Sources: Crossref, ORCID
Added: September 10, 2019

2015 journal article

Reprint of: Extracellular matrix as a biological scaffold material: Structure and function

Acta Biomaterialia, 23, S17–S26.

By: S. Badylak*, D. Freytes* & T. Gilbert*

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2014 journal article

Macrophages Modulate Engineered Human Tissues for Enhanced Vascularization and Healing

Annals of Biomedical Engineering, 43(3), 616–627.

co-author countries: United States of America 🇺🇸
author keywords: Scaffold; Vascularization; Inflammatory response; Tissue engineering; Healing
MeSH headings : Animals; Humans; Inflammation / immunology; Macrophages / physiology; Neovascularization, Physiologic; Regeneration; Tissue Engineering; Tissue Scaffolds
Source: Crossref
Added: January 21, 2021

2013 journal article

Decellularization of Human and Porcine Lung Tissues for Pulmonary Tissue Engineering

The Annals of Thoracic Surgery, 96(3), 1046–1056.

By: J. O'Neill*, R. Anfang*, A. Anandappa*, J. Costa*, J. Javidfar*, H. Wobma*, G. Singh*, D. Freytes* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bioartificial Organs; Biomechanical Phenomena; Cell Separation / methods; Elastin / physiology; Extracellular Matrix / physiology; Feasibility Studies; Humans; Immunohistochemistry; Lung / cytology; Lung Transplantation / methods; Materials Testing; Microscopy, Electron, Scanning; Sensitivity and Specificity; Swine; Tensile Strength; Tissue Engineering / methods; Tissue Scaffolds
Source: Crossref
Added: August 28, 2020

2013 journal article

The regulation of growth and metabolism of kidney stem cells with regional specificity using extracellular matrix derived from kidney

Biomaterials, 34(38), 9830–9841.

By: J. O'Neill*, D. Freytes*, A. Anandappa*, J. Oliver* & G. Vunjak-Novakovic*

co-author countries: United States of America 🇺🇸
author keywords: Extracellular matrix; Hydrogels; Kidney; Stem cells; Niche; Regional specificity
MeSH headings : Animals; Cells, Cultured; Extracellular Matrix / metabolism; Extracellular Matrix / ultrastructure; Immunohistochemistry; Kidney / cytology; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / ultrastructure; Mice; Microscopy, Electron, Scanning; Stem Cells / cytology; Stem Cells / metabolism; Stem Cells / ultrastructure; Swine
Source: Crossref
Added: August 28, 2020

2012 journal article

Macrophages modulate the viability and growth of human mesenchymal stem cells

Journal of Cellular Biochemistry, 114(1), 220–229.

By: D. Freytes*, J. Kang, I. Marcos-Campos & G. Vunjak-Novakovic

author keywords: MESENCHYMAL STEM CELLS; MACROPHAGES; INFLAMMATION
MeSH headings : Cell Communication; Cell Line; Cell Proliferation / drug effects; Cell Survival / drug effects; Coculture Techniques; Cytokines / pharmacology; Humans; Inflammation / metabolism; Inflammation / pathology; Lipopolysaccharides / pharmacology; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Models, Biological; Vascular Endothelial Growth Factor A / pharmacology
Source: Crossref
Added: January 21, 2021

2011 journal article

549 Perfusion/Decellularization of Large Animal Lungs

The Journal of Heart and Lung Transplantation, 30(4), S184–S185.

By: G. Singh*, J. Javidfar*, J. Costa*, J. Guarrera*, J. Miller*, S. Henry*, Q. Jallerat*, D. Freytes* ...

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: August 28, 2020

2011 journal article

Hybrid Gel Composed of Native Heart Matrix and Collagen Induces Cardiac Differentiation of Human Embryonic Stem Cells without Supplemental Growth Factors

Journal of Cardiovascular Translational Research, 4(5), 605–615.

co-author countries: United States of America 🇺🇸
author keywords: Tissue engineering; Cardiac differentiation; Human embryonic stem cells; Biomaterial; Native cardiac matrix
MeSH headings : Animals; Biomarkers / metabolism; Cell Differentiation; Cells, Cultured; Coculture Techniques; Collagen Type I / metabolism; Connexin 43 / metabolism; Embryonic Stem Cells / metabolism; Embryonic Stem Cells / transplantation; Extracellular Matrix / metabolism; Humans; Hydrogels; Myocardial Contraction; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / transplantation; Regenerative Medicine / methods; Swine; Time Factors; Tissue Engineering; Tissue Scaffolds; Troponin I / metabolism; Troponin T / genetics; Up-Regulation
Source: Crossref
Added: August 28, 2020

2009 journal article

Extracellular matrix as a biological scaffold material: Structure and function

Acta Biomaterialia, 5(1), 1–13.

By: S. Badylak*, D. Freytes* & T. Gilbert*

co-author countries: United States of America 🇺🇸
author keywords: Extracellular matrix; Scaffold; Remodeling; Degradation; Ultrastructure
MeSH headings : Animals; Biochemistry / methods; Biocompatible Materials / chemistry; Biomedical Engineering; Collagen / chemistry; Extracellular Matrix / chemistry; Extracellular Matrix / physiology; Freeze Drying; Humans; Materials Testing; Microscopy, Electron, Scanning; Models, Biological; Stress, Mechanical; Tissue Engineering / methods; Tissue Scaffolds
Source: Crossref
Added: August 28, 2020

2009 journal article

Geometry and force control of cell function

Journal of Cellular Biochemistry, 108(5), 1047–1058.

By: D. Freytes*, L. Wan* & G. Vunjak-Novakovic*

co-author countries: United States of America 🇺🇸
author keywords: STEM CELLS; BIOPHYSICAL REGULATION; SCAFFOLDS; BIOREACTORS; TISSUE ENGINEERING
MeSH headings : Animals; Biomedical Research; Biomimetics / methods; Cell Culture Techniques; Humans; Models, Biological; Rats; Regeneration; Stem Cells / cytology; Stem Cells / physiology; Stress, Physiological; Tissue Engineering / methods; Tissue Scaffolds; Transplants
Source: Crossref
Added: August 28, 2020

2009 journal article

Oxygen diffusivity of biologic and synthetic scaffold materials for tissue engineering

Journal of Biomedical Materials Research Part A, 91A(4), 1010–1017.

By: J. Valentin*, D. Freytes*, J. Grasman*, C. Pesyna*, J. Freund*, T. Gilbert*, S. Badylak*

co-author countries: United States of America 🇺🇸
author keywords: biologic scaffold material; extracellular matrix; tissue engineering; oxygen diffusivity; ultrastructure
MeSH headings : Animals; Biocompatible Materials / pharmacology; Diffusion / drug effects; Extracellular Matrix / drug effects; Extracellular Matrix / ultrastructure; Materials Testing; Oxygen / metabolism; Sus scrofa; Temperature; Time Factors; Tissue Engineering / methods; Tissue Scaffolds / chemistry
Source: Crossref
Added: August 28, 2020

2008 journal article

Collagen fiber alignment and biaxial mechanical behavior of porcine urinary bladder derived extracellular matrix

Biomaterials, 29(36), 4775–4782.

By: T. Gilbert*, S. Wognum*, E. Joyce*, D. Freytes*, M. Sacks* & S. Badylak*

co-author countries: United States of America 🇺🇸
author keywords: Extracellular matrix; Scaffold; Collagen fiber alignment; Biaxial mechanical behavior
MeSH headings : Animals; Biomechanical Phenomena; Elastic Modulus; Extracellular Matrix / metabolism; Fibrillar Collagens / metabolism; Mucous Membrane / metabolism; Sus scrofa / metabolism; Urinary Bladder / metabolism
Source: Crossref
Added: August 28, 2020

2008 journal article

Hydrated versus lyophilized forms of porcine extracellular matrix derived from the urinary bladder

Journal of Biomedical Materials Research Part A, 87A(4), 862–872.

By: D. Freytes*, R. Tullius*, J. Valentin*, A. Stewart-Akers* & S. Badylak*

co-author countries: United States of America 🇺🇸
author keywords: extracellular matrix; lyophilization; freeze-drying; scaffold; structural properties; urinary bladder
MeSH headings : Animals; Biocompatible Materials / chemistry; Extracellular Matrix / chemistry; Freeze Drying; Humans; Hydrostatic Pressure; Materials Testing; Mice; NIH 3T3 Cells; Permeability; Stress, Mechanical; Swine; Tissue Engineering / methods; Tissue Scaffolds / chemistry; Urinary Bladder / anatomy & histology; Urinary Bladder / chemistry; Water / chemistry
Source: Crossref
Added: August 28, 2020

2008 journal article

Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix

Biomaterials, 29(11), 1630–1637.

By: D. Freytes*, J. Martin*, S. Velankar*, A. Lee* & S. Badylak*

co-author countries: United States of America 🇺🇸
author keywords: extracellular matrix; viscoelasticity; rheology; scaffold; gel
MeSH headings : Animals; Cell Adhesion; Cell Proliferation; Cells, Cultured; Extracellular Matrix / metabolism; Extracellular Matrix / ultrastructure; Gels / chemistry; Gels / metabolism; Kinetics; Microscopy, Electron, Scanning; Myocytes, Smooth Muscle / cytology; Rats; Rheology; Swine; Tissue Scaffolds / chemistry; Urinary Bladder / metabolism; Viscosity
Source: Crossref
Added: August 28, 2020

2008 journal article

Uniaxial and biaxial properties of terminally sterilized porcine urinary bladder matrix scaffolds

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 84B(2), 408–414.

By: D. Freytes*, R. Stoner* & S. Badylak*

co-author countries: United States of America 🇺🇸
author keywords: sterilization; extracellular matrix; material properties; strength; scaffolds
MeSH headings : Animals; Biocompatible Materials; Extracellular Matrix; Materials Testing; Sterilization; Swine; Tensile Strength; Tissue Scaffolds; Urinary Bladder
Source: Crossref
Added: August 28, 2020

2006 journal article

Effect of storage upon material properties of lyophilized porcine extracellular matrix derived from the urinary bladder

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 78B(2), 327–333.

By: D. Freytes*, R. Tullius* & S. Badylak*

co-author countries: United States of America 🇺🇸
author keywords: stability; suture; scaffold; permeability; mechanical properties; urinary bladder; extracellular matrix
MeSH headings : Animals; Bioprosthesis; Extracellular Matrix; Freeze Drying; Materials Testing; Swine; Time Factors; Urinary Bladder
Source: Crossref
Added: August 28, 2020

2006 journal article

Fiber architecture and biaxial mechanical behavior of porcine urinary bladder extracellular matrix

Journal of Biomechanics, 39, S391.

By: T. Gilbert, D. Freytes*, A. Willment, M. Sacks & S. Badylak

Source: Crossref
Added: August 28, 2020

2005 journal article

Analytically derived material properties of multilaminated extracellular matrix devices using the ball-burst test

Biomaterials, 26(27), 5518–5531.

By: D. Freytes*, A. Rundell*, J. Vandegeest*, D. Vorp*, T. Webster* & S. Badylak*

co-author countries: United States of America 🇺🇸
author keywords: bladder; ECM; multilaminate devices; mechanical properties; mechanical test; ball-burst test; scaffold
MeSH headings : Animals; Biocompatible Materials / analysis; Biocompatible Materials / chemistry; Biomechanical Phenomena / methods; Compressive Strength; Computer Simulation; Elasticity; Extracellular Matrix / chemistry; Extracellular Matrix / physiology; Manufactured Materials / analysis; Materials Testing / methods; Models, Biological; Models, Chemical; Physical Stimulation / methods; Swine; Tensile Strength
Source: Crossref
Added: August 28, 2020

2005 journal article

Esophageal Reconstruction with ECM and Muscle Tissue in a Dog Model

Journal of Surgical Research, 128(1), 87–97.

By: S. Badylak*, D. Vorp*, A. Spievack*, A. Simmons-Byrd*, J. Hanke*, D. Freytes*, A. Thapa*, T. Gilbert*, A. Nieponice*

co-author countries: United States of America 🇺🇸
author keywords: extracellular matrix; urinary bladder matrix; esophagus; surgery; tissue engineering; scaffold; esophageal cancer; regenerative medicine; bioscaffold
MeSH headings : Animals; Biomechanical Phenomena; Dogs; Esophageal Stenosis / etiology; Esophageal Stenosis / prevention & control; Esophagectomy / adverse effects; Esophagus / physiopathology; Esophagus / surgery; Extracellular Matrix / physiology; Female; Models, Animal; Muscle, Smooth / physiology; Muscle, Smooth / surgery; Plastic Surgery Procedures / methods; Recovery of Function; Tissue Engineering / methods
Source: Crossref
Added: August 28, 2020

2004 journal article

Biaxial strength of multilaminated extracellular matrix scaffolds

Biomaterials, 25(12), 2353–2361.

By: D. Freytes*, S. Badylak*, T. Webster*, L. Geddes* & A. Rundell*

co-author countries: United States of America 🇺🇸
author keywords: ECM (extracellular matrix); ball-burst strength; mechanical properties; SEM (scanning electron microscopy); SIS (small intestinal submucosa); disinfection
MeSH headings : Absorbable Implants; Animals; Biocompatible Materials; Biological Factors / physiology; Cells, Cultured; Dogs; Extracellular Matrix / physiology; Extracellular Matrix / ultrastructure; Gastric Mucosa / physiology; Gastric Mucosa / ultrastructure; Humans; Jejunum / physiology; Jejunum / ultrastructure; Manufactured Materials / analysis; Materials Testing / methods; Organ Specificity; Swine; Tensile Strength / physiology; Urinary Bladder / physiology; Urinary Bladder / ultrastructure
Source: Crossref
Added: August 28, 2020

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