Works (24)

Updated: July 12th, 2023 21:19

2020 journal article

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

NATURE BIOMEDICAL ENGINEERING, 4(5), 499–506.

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Blood Glucose / metabolism; Diabetes Mellitus, Experimental / blood; Disease Models, Animal; Drug Delivery Systems; Humans; Insulin / pharmacology; Insulin Secretion / drug effects; Male; Mice, Inbred C57BL; Needles; Swine; Swine, Miniature; Transdermal Patch
Source: Web Of Science
Added: February 17, 2020

2019 journal article

Extraction of Plant DNA by Microneedle Patch for Rapid Detection of Plant Diseases

ACS Nano, 13(6), 6540–6549.

By: R. Paul n, A. Saville n, J. Hansel n, Y. Ye n, C. Ball n, A. Williams n, X. Chang*, G. Chen n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: plant disease; DNA extraction; microneedle patch; Phytophthora infestans; nucleic acid amplification; point-of-care diagnostics
MeSH headings : DNA Barcoding, Taxonomic / instrumentation; DNA Barcoding, Taxonomic / methods; DNA, Fungal / chemistry; DNA, Fungal / genetics; Solanum lycopersicum / microbiology; Metagenomics / instrumentation; Metagenomics / methods; Needles; Phytophthora / genetics; Phytophthora / pathogenicity; Plant Diseases / microbiology; Plant Leaves / chemistry; Plant Leaves / microbiology
Sources: Web Of Science, ORCID, Crossref
Added: July 15, 2019

2019 journal article

Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy

NANO RESEARCH, 12(6), 1313–1320.

By: J. Yan n, X. Zhang n, Y. Liu n, Y. Ye n, J. Yu n, Q. Chen n, J. Wang n, Y. Zhang n ...

co-author countries: United States of America 🇺🇸
author keywords: liquid metal; melanin nanoparticles; nanomedicine; shape-controlled synthesis; photothermal therapy
Source: Web Of Science
Added: June 17, 2019

2019 article

Topical and Transdermal Nanomedicines for Cancer Therapy

NANOTHERANOSTICS FOR CANCER APPLICATIONS, Vol. 5, pp. 231–251.

By: Y. Ye n, J. Wang n, W. Sun n, H. Bomba n & Z. Gu n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: October 26, 2020

2018 journal article

Cardiac cell-integrated microneedle patch for treating myocardial infarction

SCIENCE ADVANCES, 4(11).

By: J. Tang n, J. Wang n, K. Huang n, Y. Ye n, T. Su n, L. Qiao n, M. Hensley n, T. Caranasos* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Cells, Cultured; Microtechnology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Needles; Rats; Rats, Inbred WKY; Regeneration; Stromal Cells / cytology; Stromal Cells / transplantation; Swine; Tissue Engineering / instrumentation
Sources: Web Of Science, ORCID
Added: December 31, 2018

2018 journal article

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy

NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840.

By: Q. Hu n, W. Sun*, J. Wang n, H. Ruan n, X. Zhang*, Y. Ye n, S. Shen*, C. Wang n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antibodies / chemistry; Antibodies / immunology; Blood Platelets / chemistry; Blood Platelets / cytology; Blood Platelets / metabolism; Cell Line, Tumor; Chemokines / metabolism; Cytokines / metabolism; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells / chemistry; Hematopoietic Stem Cells / cytology; Hematopoietic Stem Cells / metabolism; Leukemia / therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor / deficiency; Programmed Cell Death 1 Receptor / genetics; Programmed Cell Death 1 Receptor / immunology; T-Lymphocytes / cytology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
Source: Web Of Science
Added: November 26, 2018

2018 journal article

In situ formed reactive oxygen species-responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

SCIENCE TRANSLATIONAL MEDICINE, 10(429).

By: C. Wang n, J. Wang n, X. Zhang n, S. Yu n, D. Wen n, Q. Hu n, Y. Ye n, H. Bomba n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Cell Line, Tumor; Combined Modality Therapy; Deoxycytidine / analogs & derivatives; Deoxycytidine / therapeutic use; Female; Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry; Immunotherapy / methods; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor / metabolism; Gemcitabine
Source: Web Of Science
Added: August 6, 2018

2017 review

Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs

[Review of ]. THERANOSTICS, 7(14), 3504–3516.

By: C. Wang*, W. Sun*, Y. Ye*, H. Bomba & Z. Gu*

author keywords: artificial immune cells; lymphoid organs
MeSH headings : Animals; Antigen-Presenting Cells / immunology; Artificial Cells / chemistry; Artificial Cells / immunology; Biomimetic Materials / chemistry; Humans; Lymphoid Tissue / cytology; Lymphoid Tissue / immunology
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Investigation and intervention of autophagy to guide cancer treatment with nanogels

NANOSCALE, 9(1), 150–163.

By: X. Zhang n, X. Liang*, J. Gu*, D. Chang*, J. Zhang*, Z. Chen n, Y. Ye n, C. Wang n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Autophagy; Chloroquine / administration & dosage; Doxorubicin / administration & dosage; Drug Delivery Systems; Endocytosis; Endosomes; Exocytosis; Female; Gels; Humans; MCF-7 Cells; Mice; Mice, SCID; Nanoparticles; Neoplasms, Experimental / drug therapy; Rhodamines; Xenograft Model Antitumor Assays; rab GTP-Binding Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Local delivery of checkpoints antibodies

HUMAN VACCINES & IMMUNOTHERAPEUTICS, 13(1), 245–248.

By: C. Wang n, Y. Ye n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: biomaterials; cancer immunotherapy; drug delivery; immune checkpoint inhibitors; microneedle
MeSH headings : Antibodies / administration & dosage; Biomedical Research / trends; Humans; Immunologic Factors / administration & dosage; Immunotherapy / methods; Molecular Targeted Therapy / methods; Neoplasms / immunology; Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Red Blood Cells for Glucose-Responsive Insulin Delivery

ADVANCED MATERIALS, 29(18).

co-author countries: United States of America 🇺🇸
MeSH headings : Erythrocytes; Glucose; Insulin
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook

ADVANCED MATERIALS, 29(29).

By: C. Wang n, Y. Ye n, Q. Hu n, A. Bellotti n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: biomaterials; cancer immunotherapy; cell therapy; drug delivery
MeSH headings : Animals; Antigen-Presenting Cells / cytology; Antigen-Presenting Cells / metabolism; Antigens / genetics; Antigens / immunology; Antigens / metabolism; Biocompatible Materials / chemistry; Cell- and Tissue-Based Therapy; Humans; Immunologic Factors / metabolism; Immunologic Factors / therapeutic use; Immunotherapy; Nanostructures / chemistry; Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Ultrasound-triggered noninvasive regulation of blood glucose levels using microgels integrated with insulin nanocapsules

Nano Research, 10(4), 1393–1402.

By: J. Di n, J. Yu n, Q. Wang*, S. Yao n, D. Suo n, Y. Ye n, M. Pless n, Y. Zhu n, Y. Jing n, Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: controlled drug delivery; focused ultrasound; diabetes; nanocapsule; microgel
Sources: Web Of Science, Crossref
Added: August 6, 2018

2016 journal article

Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody

NANO LETTERS, 16(4), 2334–2340.

By: C. Wang n, Y. Ye n, G. Hochu n, H. Sadeghifar n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: Anti-PD-1; cancer immunotherapy; microneedle patch; melanoma; drug delivery
MeSH headings : Animals; Antibodies, Neoplasm / immunology; Antibodies, Neoplasm / pharmacology; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Immunotherapy / instrumentation; Immunotherapy / methods; Mice; Needles; Programmed Cell Death 1 Receptor / immunology; Skin Neoplasms / immunology; Skin Neoplasms / pathology; Skin Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Internalized compartments encapsulated nanogels for targeted drug delivery

NANOSCALE, 8(17), 9178–9184.

By: J. Yu n, Y. Zhang n, W. Sun n, C. Wang n, D. Ranson n, Y. Ye n, Y. Weng*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Doxorubicin / administration & dosage; Drug Delivery Systems; Ferrous Compounds; Hyaluronic Acid; Nanoparticles; Silicon Dioxide
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery

Advanced Materials, 28(16), 3115–3121.

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Blood Glucose / analysis; Blood Glucose / metabolism; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Experimental / pathology; Insulin / metabolism; Insulin Secretion; Islets of Langerhans / metabolism; Mice; Needles; Time Factors
Sources: Web Of Science, Crossref
Added: August 6, 2018

2016 journal article

Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration

ACS NANO, 10(1), 1292–1299.

By: D. Shi*, X. Xu*, Y. Ye n, K. Song*, Y. Cheng, J. Di n, Q. Hu n, J. Li ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; tissue engineering; hydrogel; regenerative medicine; nanoparticles
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors

ACS NANO, 10(9), 8956–8963.

By: Y. Ye n, J. Wang n, Q. Hu n, G. Hochu n, H. Xin n, C. Wang n, Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: drug delivery; immunotherapy; anti-PD1; IDO; microneedle
MeSH headings : Animals; Cell Cycle Checkpoints / drug effects; Drug Delivery Systems; Immunosuppression Therapy; Immunotherapy / methods; Indoleamine-Pyrrole 2,3,-Dioxygenase / therapeutic use; Melanoma / therapy; Programmed Cell Death 1 Receptor / therapeutic use; Skin Neoplasms / therapy; Tumor Microenvironment
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots

NANO LETTERS, 16(2), 1118–1126.

By: Q. Hu n, W. Sun n, Y. Lu n, H. Bomba n, Y. Ye n, T. Jiang*, A. Isaacson*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Drug delivery; stimuli-responsive; tumor microenvironment; apoptosis; antiangiogenesis
MeSH headings : Angiogenesis Inhibitors / administration & dosage; Angiogenesis Inhibitors / chemistry; Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Apoptosis / drug effects; Breast Neoplasms / drug therapy; Breast Neoplasms / genetics; Cell Line, Tumor; Cell Membrane Permeability / drug effects; Drug Delivery Systems; Endosomes / drug effects; Gene Transfer Techniques; Humans; Hyaluronoglucosaminidase / biosynthesis; Hyaluronoglucosaminidase / chemistry; Mice; Snake Venoms / administration & dosage; Snake Venoms / chemistry; TNF-Related Apoptosis-Inducing Ligand / administration & dosage; Tumor Microenvironment / drug effects; Xenograft Model Antitumor Assays
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Versatile Protein Nanogels Prepared by In Situ Polymerization

MACROMOLECULAR CHEMISTRY AND PHYSICS, 217(3), 333–343.

By: Y. Ye n, J. Yu n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: drug delivery; in situ polymerization; nanogels; protein; stimuli-responsive
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Engineering Synthetic Insulin-Secreting Cells Using Hyaluronic Acid Microgels Integrated with Glucose-Responsive Nanoparticles

CELLULAR AND MOLECULAR BIOENGINEERING, 8(3), 445–454.

By: J. Di n, J. Yu n, Y. Ye n, D. Ranson n, A. Jindal n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: Insulin delivery; Diabetes; Glucose responsive; Bio-inspired; Hyaluronic acid; Dextran
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265.

By: J. Yu n, Y. Zhang n, Y. Ye n, R. DiSanto n, W. Sun n, D. Ranson n, F. Ligler n, J. Buse*, Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: diabetes; drug delivery; glucose-responsive; hypoxia-sensitive; microneedle
MeSH headings : Animals; Blood Glucose / analysis; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Glucose / metabolism; Glucose Oxidase / metabolism; Humans; Hyaluronic Acid / chemistry; Hyaluronic Acid / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Hypoxia / metabolism; Insulin / administration & dosage; Insulin / chemistry; Insulin / metabolism; Male; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidation-Reduction; Reproducibility of Results
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Stretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots

ACS NANO, 9(9), 9407–9415.

By: J. Di n, S. Yao n, Y. Ye n, Z. Cui n, J. Yu n, T. Ghosh n, Y. Zhu n, Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: drug delivery; wearable devices; stimuli-responsive; nanoparticles; microdepots
MeSH headings : Animals; Drug Delivery Systems; Drug Liberation; Elastomers / chemistry; Elastomers / pharmacology; Mice; Nanoparticles / chemistry; Polymers / chemistry; Polymers / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

journal article

Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery

Wang, J. Q., Ye, Y. Q., Yu, J. C., Kahkoska, A. R., Zhang, X. D., Wang, C., … Gu, Z. ACS Nano, 12(3), 2466–2473.

By: J. Wang, Y. Ye, J. Yu, A. Kahkoska, X. Zhang, C. Wang, W. Sun, R. Corder ...

Source: NC State University Libraries
Added: August 6, 2018

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