Golden Leaf Biomanufacturing Training and Education Center

Works Published in 2016

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Displaying all 7 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 magazine article

Process-oriented Training in Single-use Technology

BioProcess International Supplement Series.

Contributors: G. Gilleskie

Source: ORCID
Added: October 16, 2022

2016 journal article

A Life Cycle Approach to Education and Training for the Biopharmaceutical Industry

Chemical Engineering Education. https://journals.flvc.org/cee/article/view/88298

Contributors: G. Gilleskie, B. Reeves, J. Zanten, J. Balchunas & R. Carbonell

Source: ORCID
Added: October 16, 2022

2016 journal article

Development of a stability indicating method for green fluorescent protein by HPLC

LC GC North America, 34(10), 798-.

By: N. Hentz & B. Mosley

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Design of protease-resistant peptide ligands for the purification of antibodies from human plasma

Journal of Chromatography A, 1445, 93–104.

By: S. Menegatti n, B. Bobay n, K. Ward n, T. Islam n, W. Kish n, A. Naik n, R. Carbonell n

author keywords: Peptide affinity ligands; Polyclonal antibodies; Affinity chromatography; Proteolysis; Protease; Molecular docking
MeSH headings : Animals; Antibodies / isolation & purification; Binding Sites; Blood Chemical Analysis / methods; Chromatography, Affinity; Chymotrypsin / metabolism; Humans; Ligands; Peptides / chemistry; Protein Binding; Trypsin / metabolism
TL;DR: A strategy is presented for developing variants of peptide ligands with enhanced biochemical stability for the purification of antibodies from animal sera and higher selectivity than the original sequences, due to electrical neutrality. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Reducing diffusion limitations in Ion exchange grafted membranes using high surface area nonwovens

JOURNAL OF MEMBRANE SCIENCE, 514, 53–64.

By: M. Heller n, R. Wimbish n, P. Gurgel n, B. Pourdeyhimi n & R. Carbonell n

author keywords: UV grafting; Islands-in-the-sea nonwoven; Diffusion limited; Ion exchange protein capture; Shrinking core
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs

IMMUNOGENETICS, 68(3), 205–217.

By: S. Friedenberg n, G. Buhrman n, L. Chdid n, N. Olby n, T. Olivry n, J. Guillaumin*, T. O'Toole*, R. Goggs* ...

author keywords: Canine; Immune-mediated disease; Dog leukocyte antigen; Major histocompatibility complex class Ib
MeSH headings : Alleles; Amino Acid Substitution; Animals; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Binding Sites; Dog Diseases / genetics; Dog Diseases / immunology; Dogs; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / immunology; Immune System Diseases / veterinary; Meta-Analysis as Topic; Models, Molecular; Peptides / chemistry; Peptides / metabolism; Phenotype; Polymorphism, Single Nucleotide; Protein Conformation; Reproducibility of Results; Structure-Activity Relationship
TL;DR: A strong association is demonstrated between two polymorphic positions (10 bp apart) in exon 2 of one allele in D LA-79, DLA-79*001:02, and multiple immune-mediated diseases, resulting in F33L and N37D amino acid changes that are likely to affect critical interactions with the peptide N-terminus. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Affinity interactions of human immunoglobulin G with short peptides: role of ligand spacer on binding, kinetics, and mass transfer

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408(7), 1829–1841.

author keywords: Peptide ligands; Immunoglobulin G; Peptide HWRGWV; Spacer arms; Quartz crystal microbalance
MeSH headings : Adsorption; Amino Acid Sequence; Humans; Immunoglobulin G / metabolism; Kinetics; Ligands; Peptides / chemistry; Peptides / metabolism; Polyethylene Glycols / chemistry; Protein Binding; Quartz Crystal Microbalance Techniques / methods; Silicon Dioxide / chemistry
TL;DR: Light was shed on interfacial effects important for detection and bioseparation by following the shifts in frequency and energy dissipation in a quartz crystal microbalance, as well as thermodynamic and kinetics parameters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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