Works Published in 2009
Displaying works 561 - 580 of 632 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 journal article
Manganese Tissue Dosimetry in Rats and Monkeys: Accounting for Dietary and Inhaled Mn with Physiologically based Pharmacokinetic Modeling
TOXICOLOGICAL SCIENCES, 108(1), 22–34.
author keywords: manganese; nonhuman primates; dose-dependent regulation; saturable tissue binding; asymmetrical diffusional flux; biliary induction; inhalation exposures; PBPK
MeSH headings : Administration, Inhalation; Administration, Oral; Animals; Brain Chemistry; Calibration; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Inhalation Exposure / analysis; Liver / chemistry; Macaca mulatta; Manganese / administration & dosage; Manganese / pharmacokinetics; Models, Biological; Rats; Sensitivity and Specificity
TL;DR:
A physiologically based pharmacokinetic model for Mn in rats and scale the model to describe Mn tissue accumulation in nonhuman primates exposed to Mn by inhalation and diet are complete and consistent with the available experimental kinetic data.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Managing canine vector-borne diseases of zoonotic concern: part one
Trends in Parasitology, 25(4), 157–163.
MeSH headings : Animals; Disease Reservoirs / microbiology; Disease Reservoirs / parasitology; Disease Reservoirs / veterinary; Disease Vectors; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Humans; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / parasitology
TL;DR:
This review focuses on the zoonotic relevance of CVBDs, the significance of co-infection and the role of infected but clinically healthy dogs in spreading different pathogens among human and canine populations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Intrinsic Limitations on the vertical bar E vertical bar(4) Dependence of the Enhancement Factor for Surface-Enhanced Raman Scattering
JOURNAL OF PHYSICAL CHEMISTRY C, 113(15), 5912–5919.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Interaction of the porcine reproductive and respiratory syndrome virus nucleocapsid protein with the inhibitor of MyoD family-a domain-containing protein
BIOLOGICAL CHEMISTRY, 390(3), 215–223.
author keywords: arterivirus; HIC; inhibitor of MyoD family-a (I-mfa) domain-containing protein; nucleocapsid; porcine reproductive and respiratory syndrome ( PRRS); PRRS virus ( PRRSV); yeast two-hybrid assay
MeSH headings : Animals; Base Sequence; Cell Line; DNA Primers; MyoD Protein / antagonists & inhibitors; Nucleocapsid Proteins / metabolism; Porcine respiratory and reproductive syndrome virus / metabolism; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Swine; Viral Proteins / metabolism; Zinc / metabolism
TL;DR:
Yeast two-hybrid screening identified the inhibitor of MyoD family-a (I-mfa) domain-containing protein (HIC) as a cellular partner for PRRS virus (PRRSV) N protein, a homolog of human HIC, a recently identified cellular transcription factor.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Intact and Top-Down Characterization of Biomolecules and Direct Analysis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Coupled to FT-ICR, Mass Spectrometry
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 20(4), 667–673.
MeSH headings : Amino Acid Sequence; Animals; Carbohydrates / chemistry; Cattle; Chickens; Egg Yolk / chemistry; Horses; Lipids / chemistry; Milk / chemistry; Molecular Sequence Data; Mucins / chemistry; Mucins / metabolism; Myoglobin / chemistry; Polysaccharides / chemistry; Polysaccharides / metabolism; Proteins / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectroscopy, Fourier Transform Infrared / methods
TL;DR:
Three of the four classes of biological macromolecules have been ionized and detected using MALDESI with minimal sample preparation and Sequencing of O-linked glycans, cleaved from mucin using reductive β-elimination chemistry, is also demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 40(3), 349–358.
author keywords: carbon nanotubes; asthma; fibrosis; lung
MeSH headings : Administration, Inhalation; Aerosols; Animals; Asthma / chemically induced; Asthma / immunology; Asthma / pathology; Bronchoalveolar Lavage Fluid / cytology; Fibrosis / chemically induced; Fibrosis / immunology; Fibrosis / pathology; Humans; Interleukin-13 / immunology; Lung / cytology; Lung / immunology; Lung / pathology; Macrophages / cytology; Macrophages / metabolism; Male; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / adverse effects; Nanotubes, Carbon / ultrastructure; Ovalbumin / immunology; Particle Size; Platelet-Derived Growth Factor / immunology; Random Allocation; Transforming Growth Factor beta1 / immunology
TL;DR:
It is indicated that individuals with pre-existing allergic inflammation may be susceptible to airway fibrosis from inhaled multiwalled carbon nanotubes, and combined ovalbumin sensitization and MWCNT inhalation also synergistically increased IL-5 mRNA levels, which could further contribute to airways fibrosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Genotyping of Campylobacter coli isolated from humans and retail meats using multilocus sequence typing and pulsed-field gel electrophoresis
JOURNAL OF APPLIED MICROBIOLOGY, 106(5), 1722–1733.
author keywords: antimicrobial resistance; Campylobacter coli; humans; multilocus sequence typing; pulsed-field gel electrophoresis; retail meats
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Campylobacter Infections / microbiology; Campylobacter coli / classification; Campylobacter coli / drug effects; Campylobacter coli / genetics; Cattle; Chickens; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Food Microbiology; Genetic Variation; Genotype; Humans; Meat / microbiology; Microbial Sensitivity Tests; Phenotype; Phylogeny; Swine; Turkeys
TL;DR:
The objective is to determine the antimicrobial resistant profiles and clonality of Campylobacter coli isolated from clinically ill humans and retail meats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 review
Genome-wide association for major depressive disorder: A possible role for the presynaptic protein piccolo
[Review of ]. Molecular Psychiatry, 14(4), 359–375.
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(8), 2794–2799.
MeSH headings : Amyotrophic Lateral Sclerosis / genetics; Amyotrophic Lateral Sclerosis / pathology; Animals; Base Sequence; DNA Primers; Disease Models, Animal; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Genome; Genome-Wide Association Study; Homozygote; Immunohistochemistry; Muscular Diseases / genetics; Muscular Diseases / pathology; Muscular Diseases / veterinary; Mutation, Missense; Polymerase Chain Reaction; Species Specificity; Superoxide Dismutase / genetics
TL;DR:
These findings identify canine DM to be the first recognized spontaneously occurring animal model for ALS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Generation of Multiply Charged Peptides and Proteins by Radio Frequency Acoustic Desorption and Ionization for Mass Spectrometric Detection
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 20(4), 597–600.
MeSH headings : Electrodes; Equipment Design; Mass Spectrometry / instrumentation; Mass Spectrometry / methods; Natriuretic Peptide, Brain / chemistry; Peptides / chemistry; Proteins / chemistry; Quartz / chemistry; Ubiquitin / chemistry
TL;DR:
The design and implementation of a radio frequency acoustic desorption ionization (RADIO) source has been demonstrated and intact and dissociated species observed during MS and MS/MS experiments, respectively are confirmed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Fast and Robust Route to Hydroporphyrin-Chalcones with Extended Red or Near-Infrared Absorption
ORGANIC LETTERS, 11(8), 1761–1764.
MeSH headings : Aldehydes / chemistry; Chalcones / chemical synthesis; Chalcones / chemistry; Combinatorial Chemistry Techniques; Microwaves; Molecular Structure; Photochemistry; Porphyrins / chemical synthesis; Porphyrins / chemistry; Spectrophotometry, Infrared; Spectroscopy, Near-Infrared; Stereoisomerism
TL;DR:
The reaction of an acetylchlorin or diacetylbacteriochlorin with an aldehyde under microwave conditions readily affords the corresponding hydroporphyrin-chalcone, which should make such constructs valuable for fundamental spectroscopic studies as well as diverse photochemical applications in the relatively unexplored red and near-infrared spectral regions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors
Veterinary Research, 40(2), 29.
author keywords: Bartonella; vectors; ecological fitness; host adaptation; pathogenesis
MeSH headings : Adaptation, Physiological; Animals; Bartonella / classification; Bartonella / physiology; Disease Reservoirs; Ecosystem; Humans; Insect Vectors / microbiology; Insecta / microbiology
TL;DR:
Bacterial type IV secretion systems, which are supra-molecular transporters ancestrally related to bacterial conjugation systems, represent crucial pathogenicity factors that have contributed to a radial expansion of the Bartonella lineage in nature by facilitating adaptation to unique mammalian hosts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep
NATURE GENETICS, 41(3), 371–375.
MeSH headings : Animals; Animals, Genetically Modified; Animals, Inbred Strains; Drosophila / genetics; Drosophila Proteins / genetics; Female; Gene Expression Regulation / physiology; Gene Regulatory Networks / physiology; Genes, Insect; Genetic Variation / physiology; Genome, Insect; Genome-Wide Association Study / veterinary; Male; Models, Biological; Molecular Sequence Data; Polymorphism, Genetic; Sleep / genetics
TL;DR:
It is independently confirmed that molecular polymorphisms in Catsup (Catecholamines up) are associated with variation in sleep and that P-element mutations in four candidate genes affect sleep and gene expression and co-regulated gene expression using P- element mutants are confirmed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Longitudinal Study of Salmonella Dispersion and the Role of Environmental Contamination in Commercial Swine Production Systems
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 75(6), 1478–1486.
MeSH headings : Amplified Fragment Length Polymorphism Analysis; Animals; Anti-Bacterial Agents / pharmacology; Bacterial Typing Techniques; Cluster Analysis; Cohort Studies; Cross-Sectional Studies; DNA Fingerprinting; DNA, Bacterial / genetics; Environmental Microbiology; Longitudinal Studies; Microbial Sensitivity Tests; Prevalence; Salmonella / classification; Salmonella / isolation & purification; Salmonella Infections, Animal / microbiology; Serotyping; Swine; Swine Diseases / microbiology
TL;DR:
The roles of various environmental sources, such as truck-washing systems, waste-processing lagoons, and other sources, as potential contributors to the exposure and dissemination of Salmonella in commercial swine production systems are investigated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
A model for HCMV infection in immunosuppressed patients
MATHEMATICAL AND COMPUTER MODELLING, 49(7-8), 1653–1663.
author keywords: HCMV; CMV; Herpes; Transplantation; Mathematical model; Immunosuppression
TL;DR:
Simulations with the approximated parameter values demonstrates that the model is capable of describing primary, latent, and secondary (reactivated) HCMV infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 chapter
Development and application of naturally renewable scaffold materials for bone tissue engineering
In L. A. Lucia & O. J. Rojas (Eds.), Nanotechnology of renewable materials.
Ed(s): . L. A. Lucia & O. Rojas
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
The Role of L-monocytogenes Serotype 4b gtcA in Gastrointestinal Listeriosis in A/J Mice
FOODBORNE PATHOGENS AND DISEASE, 6(1), 39–48.
MeSH headings : Animals; Bacterial Adhesion / genetics; Bacterial Adhesion / physiology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Proteins / physiology; Caco-2 Cells / microbiology; Disease Models, Animal; Female; Gastrointestinal Tract / microbiology; Genes, Bacterial; Glycosylation; Humans; Listeria monocytogenes / classification; Listeria monocytogenes / genetics; Listeria monocytogenes / pathogenicity; Listeriosis / microbiology; Mice; Mutation; Serotyping; Teichoic Acids / metabolism; Virulence / genetics
TL;DR:
A role for gtcA in the pathogenesis of gastrointestinal listeriosis in mice is demonstrated, and diminished ability of gTCA mutants to invade intestinal epithelial cells may be partly responsible for decreased gastrointestinal virulence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats
HORMONES AND BEHAVIOR, 55(2), 319–328.
author keywords: DPN; PPT; Estrogen; Soy isoflavones; Testosterone; Anxiety; Endocrine active compound; Resveratrol; Equol; Plus maze; ER beta; Estrogen receptor beta
MeSH headings : Analysis of Variance; Animals; Anti-Anxiety Agents / administration & dosage; Anxiety / drug therapy; Behavior, Animal / drug effects; Equol; Estrogen Receptor alpha / agonists; Isoflavones / administration & dosage; Male; Nitriles / administration & dosage; Nitriles / blood; Phenols; Phytoestrogens / administration & dosage; Propionates / administration & dosage; Propionates / blood; Pyrazoles / administration & dosage; Rats; Rats, Long-Evans; Rats, Wistar; Resveratrol; Stilbenes / administration & dosage; Testosterone / blood
TL;DR:
It is determined that DPN can be successfully administered either orally or by subcutaneous injection, although plasma DPN levels are significantly lower if given orally, and the efficacy of ERbeta agonists may depend on gonadal status, therefore the therapeutic potential of ER beta selective agonists to treat mood disorders may be limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Soy-Derived Isoflavones Inhibit the Growth of Canine Lymphoid Cell Lines
CLINICAL CANCER RESEARCH, 15(4), 1269–1276.
MeSH headings : Animals; Apoptosis / drug effects; Caspase 3 / physiology; Caspase 9 / physiology; Cell Line, Tumor; Cell Proliferation / drug effects; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Genistein / pharmacology; Lymphoma, B-Cell / drug therapy; Lymphoma, B-Cell / pathology; Lymphoma, B-Cell / veterinary; Male; Polysaccharides / pharmacology; Proto-Oncogene Proteins c-bcl-2 / analysis; bcl-2-Associated X Protein / analysis
TL;DR:
The notion that canine high-grade B-cell lymphoma may represent a relevant large animal model of human non-Hodgkin's lymphoma to investigate the utility of GCP in chemopreventive and/or treatment strategies that may serve as a prelude to human clinical lymphoma trials is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Reovirus mu 2 Protein Inhibits Interferon Signaling through a Novel Mechanism Involving Nuclear Accumulation of Interferon Regulatory Factor 9
JOURNAL OF VIROLOGY, 83(5), 2178–2187.
MeSH headings : Animals; Cell Nucleus / metabolism; Cells, Cultured; Gene Expression Regulation; Humans; Interferon-Stimulated Gene Factor 3 / metabolism; Interferon-Stimulated Gene Factor 3, gamma Subunit / metabolism; Interferon-alpha / pharmacology; Interferon-beta / pharmacology; Mammalian orthoreovirus 3 / genetics; Mammalian orthoreovirus 3 / metabolism; Mammalian orthoreovirus 3 / pathogenicity; Mice; Myocarditis / virology; Orthoreovirus, Mammalian / genetics; Orthoreovirus, Mammalian / metabolism; Orthoreovirus, Mammalian / pathogenicity; Reassortant Viruses / genetics; Reassortant Viruses / metabolism; Reassortant Viruses / pathogenicity; STAT1 Transcription Factor / metabolism; STAT2 Transcription Factor / metabolism; Transcriptional Activation; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR:
The first report of an increase in IRF9 nuclear accumulation associated with viral subversion of the IFN response and couple virus strain-specific differences in IFN antagonism to the pathogenesis of viral myocarditis are reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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