Kimberly Anne Nellenbach

Works (20)

Updated: September 11th, 2023 08:10

2023 journal article

Influence of Fibrinogen Concentrate on Neonatal Clot Structure When Administered Ex Vivo After Cardiopulmonary Bypass

ANESTHESIA AND ANALGESIA, 137(3), 682–690.

By: N. Moiseiwitsch n, K. Nellenbach n, L. Downey*, D. Boorman*, A. Brown n & N. Guzzetta*

Source: Web Of Science
Added: September 5, 2023

2022 journal article

A Unique Crustacean-Based Chitin Platform to Reduce Self-Aggregation of Polysaccharide Nanofibers

FIBERS, 10(10).

By: C. Londono-Zuluaga n, H. Jameel n, R. Gonzalez n, K. Nellenbach n, A. Brown n, G. Yang*, L. Lucia n

author keywords: polysaccharide nanofibers; crustacean shells; chitin; cellulose; self-aggregation; clotting; foams
Sources: Web Of Science, ORCID
Added: October 19, 2022

2022 article

On-demand, remote and lossless manipulation of biofluid droplets

Wang, W., Sun, J., Vallabhuneni, S., Pawlowski, B., Vahabi, H., Nellenbach, K., … Kota, A. K. (2022, September 7). MATERIALS HORIZONS.

By: W. Wang n, J. Sun*, S. Vallabhuneni n, B. Pawlowski*, H. Vahabi*, K. Nellenbach n, A. Brown n, F. Scholle n, J. Zhao*, A. Kota n

MeSH headings : Humans; Pandemics / prevention & control; Saliva; Disease Outbreaks; Point-of-Care Systems; Health Personnel
Source: Web Of Science
Added: September 19, 2022

2022 article

Platelet-mimicking procoagulant nanoparticles: Potential strategies for mitigating blood shortages

Nellenbach, K., & Brown, A. C. (2022, April 19). JOURNAL OF THROMBOSIS AND HAEMOSTASIS.

By: K. Nellenbach n & A. Brown n

MeSH headings : Blood Platelets; Humans; Nanoparticles; Platelet Activation
Source: Web Of Science
Added: May 2, 2022

2021 journal article

Differential sialic acid content in adult and neonatal fibrinogen mediates differences in clot polymerization dynamics

BLOOD ADVANCES, 5(23), 5202–5214.

By: K. Nellenbach, A. Kyu, N. Guzzetta & A. Brown

MeSH headings : Adult; Fibrin; Fibrinogen; Fibrinopeptide A; Humans; Infant, Newborn; N-Acetylneuraminic Acid; Polymerization
Source: Web Of Science
Added: January 3, 2022

2021 article

Ex Vivo and In Vivo Evaluation of Fibrinogen Concentrate to Mitigate Post-Surgical Bleeding in Neonates

Moiseiwitsch, N., Nellenbach, K. A., Guzzetta, N. A., Brown, A. C., & Downey, L. (2021, November 23). BLOOD, Vol. 138.

By: N. Moiseiwitsch n, K. Nellenbach n, N. Guzzetta*, A. Brown n & L. Downey*

Source: Web Of Science
Added: September 6, 2022

2021 journal article

Fibrin-modulating nanogels for treatment of disseminated intravascular coagulation

BLOOD ADVANCES, 5(3), 613–627.

By: E. Mihalko n, M. Sandry n, N. Mininni n, K. Nellenbach n, H. Deal n, M. Daniele n, K. Ghadimi*, J. Levy*, A. Brown n

MeSH headings : Disseminated Intravascular Coagulation / drug therapy; Fibrin; Humans; Microcirculation; Nanogels; Thrombosis / drug therapy
Source: Web Of Science
Added: March 22, 2021

2021 article

Fibrin-specific poly(N-isopropylacrylamide) nanogels for targeted delivery of tissue-type plasminogen activator to treat thrombotic complications are well tolerated in vivo

Mihalko, E. P., Nellenbach, K., Krishnakumar, M., Moiseiwitsch, N., Sollinger, J., Cooley, B. C., & Brown, A. C. (2021, December 11). BIOENGINEERING & TRANSLATIONAL MEDICINE.

By: E. Mihalko n, K. Nellenbach n, M. Krishnakumar n, N. Moiseiwitsch n, J. Sollinger n, B. Cooley*, A. Brown n

author keywords: disseminated intravascular coagulation; fibrin; nanogels; pNIPAM; targeted delivery; thrombosis; tissue plasminogen activator
Source: Web Of Science
Added: December 20, 2021

2021 journal article

Modeling and Parameter Subset Selection for Fibrin Polymerization Kinetics with Applications to Wound Healing

BULLETIN OF MATHEMATICAL BIOLOGY, 83(5).

By: K. Pearce n, K. Nellenbach n, R. Smith n, A. Brown n & M. Haider n

author keywords: Wound healing; Fibrin polymerization; Kinetics model; Parameter identifiability; Subset selection
MeSH headings : Animals; Cells, Cultured; Fibrin / metabolism; Humans; Kinetics; Models, Biological; Polymerization; Wound Healing
Sources: Web Of Science, ORCID
Added: March 23, 2021

2021 article

Platelet-like particles reduce coagulopathy-related and neuroinflammatory pathologies post-experimental traumatic brain injury

Todd, J., Bharadwaj, V. N., Nellenbach, K., Nandi, S., Mihalko, E., Copeland, C., … Stabenfeldt, S. E. (2021, June 11). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS.

By: J. Todd*, V. Bharadwaj*, K. Nellenbach n, S. Nandi n, E. Mihalko n, C. Copeland*, A. Brown n, S. Stabenfeldt*

author keywords: blood-brain barrier; coagulopathy; neuroinflammation; permeability; platelet-like particles; traumatic brain injury
MeSH headings : Animals; Blood Platelets / metabolism; Blood-Brain Barrier / metabolism; Brain Injuries, Traumatic / complications; Brain Injuries, Traumatic / drug therapy; Brain Injuries, Traumatic / metabolism; Disease Models, Animal; Mice; Microglia / metabolism
Source: Web Of Science
Added: June 21, 2021

2021 journal article

Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses

COLLOIDS AND SURFACES B-BIOINTERFACES, 204.

By: C. Roosa n, I. Muhamed n, A. Young n, K. Nellenbach n, M. Daniele n, F. Ligler n, A. Brown n

author keywords: Fibrin; Nanoparticles; Wound healing; Regenerative medicine; Fibrin sealant
MeSH headings : Fibrin; Fibrin Tissue Adhesive; Nanoparticles; Polymerization; Wound Healing
Source: Web Of Science
Added: July 19, 2021

2021 journal article

Synthetic Platelet Microgels Containing Fibrin Knob B Mimetic Motifs Enhance Clotting Responses

ADVANCED THERAPEUTICS, 4(5).

By: S. Nandi n, E. Mihalko n, K. Nellenbach n, M. Castaneda n, J. Schneible n, M. Harp*, H. Deal n, M. Daniele n ...

author keywords: bleeding; Clotting; fibrin; hemostasis; microgel
Sources: Web Of Science, ORCID
Added: April 5, 2021

2020 journal article

Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet-like particles

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 108(6), 2599–2609.

By: E. Chee n, S. Nandi n, K. Nellenbach n, E. Mihalko n, D. Snider n, L. Morrill n, A. Bond n, E. Sproul n ...

author keywords: antimicrobial; microgels; nanosilver; platelet-mimetic; wound healing
MeSH headings : Acrylic Resins / chemistry; Animals; Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacology; Bacterial Infections / drug therapy; Bacterial Infections / microbiology; Blood Platelets; Clot Retraction; Colony-Forming Units Assay; Fibrin / chemistry; Fibrin / immunology; Gels; Hemorrhage / drug therapy; Hemostasis / drug effects; Liver / injuries; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Microgels; Silver / administration & dosage; Silver / chemistry; Wound Healing
Sources: Web Of Science, ORCID
Added: March 16, 2020

2020 article

Neonatal Fibrin Scaffolds Promote Enhanced Cell Adhesion, Migration, and Wound Healing In Vivo Compared to Adult Fibrin Scaffolds

CELLULAR AND MOLECULAR BIOENGINEERING.

By: K. Nellenbach n, S. Nandi n, C. Peeler n, A. Kyu n & A. Brown n

Source: Web Of Science
Added: June 15, 2020

2020 journal article

Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 577, 406–418.

By: S. Nandi n, L. Sommerville*, K. Nellenbach n, E. Mihalko n, M. Erb n, D. Freytes n, M. Hoffman*, D. Monroe*, A. Brown n

author keywords: Fibrin; Biomimetic; Platelet; Hemophilia; Biomaterials
MeSH headings : Blood Coagulation; Blood Platelets; Fibrin; Plasma; Wound Healing
Source: Web Of Science
Added: August 24, 2020

2020 journal article

Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair

ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(5), 3026–3036.

By: S. Nandi n, K. Mohanty n, K. Nellenbach n, M. Erb n, M. Muller n & A. Brown n

author keywords: biomimetic; fibrin; wound healing clot retraction; artificial platelet
MeSH headings : Blood Coagulation; Blood Platelets; Clot Retraction; Fibrin; Wound Healing
Source: Web Of Science
Added: June 8, 2020

2019 journal article

Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes

BIOMATERIALS SCIENCE, 7(2), 669–682.

By: S. Nandi n, E. Sproul n, K. Nellenbach n, M. Erb n, L. Gaffney n, D. Freytes n, A. Brown n

MeSH headings : Animals; Biomimetic Materials / chemistry; Blood Platelets / metabolism; Blood Platelets / physiology; Fibrin / chemistry; Fibrin / pharmacology; Humans; Mechanical Phenomena; Mice; Platelet Activation / drug effects; Skin / drug effects; Skin / injuries; Wound Healing / drug effects
Source: Web Of Science
Added: February 18, 2019

2018 journal article

Analysis of the structural and mechanical effects of procoagulant agents on neonatal fibrin networks following cardiopulmonary bypass

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 16(11), 2159–2167.

By: K. Nellenbach n, N. Guzzetta* & A. Brown n

author keywords: activated factor VII; cardiopulmonary bypass; fibrin; neonatal coagulation; prothrombin complex concentrate; transfusion
MeSH headings : Blood Coagulation; Blood Coagulation Factors / therapeutic use; Blood Coagulation Tests; Blood Transfusion; Cardiopulmonary Bypass; Coagulants / therapeutic use; Factor VIIa / therapeutic use; Fibrin / chemistry; Fibrinogen / chemistry; Fibrinolysis; Hemorrhage; Hemostatics / therapeutic use; Humans; Infant, Newborn; Neonatology; Recombinant Proteins / therapeutic use; Risk
Source: Web Of Science
Added: December 3, 2018

2018 journal article

Viscoelastic properties of microgel thin films control fibroblast modes of migration and pro-fibrotic responses

BIOMATERIALS, 185, 371–382.

By: D. Chester n, R. Kathard n, J. Nortey n, K. Nellenbach n & A. Brown n

author keywords: Microgels; Colloidal thin film; Fibroblasts; Mechanotransduction; Self-healing
MeSH headings : Biocompatible Materials / chemistry; Cell Adhesion; Cell Differentiation; Cell Line; Cell Movement; Elastic Modulus; Fibroblasts / cytology; Fibrosis / etiology; Gels / chemistry; Humans; Mechanotransduction, Cellular; Viscosity
Source: Web Of Science
Added: November 12, 2018

2017 journal article

Peptide Mimetic Drugs for Modulating Thrombosis and Hemostasis

DRUG DEVELOPMENT RESEARCH, 78(6), 236–244.

By: K. Nellenbach n & A. Brown n

author keywords: thrombosis; hemostasis; peptide-mimetic; fibrinogen; thrombin; platelet
MeSH headings : Animals; Blood Coagulation; Fibrinolytic Agents / pharmacology; Hemostasis / drug effects; Humans; Peptidomimetics / pharmacology; Risk Factors; Thrombosis / drug therapy
Source: Web Of Science
Added: August 6, 2018