Works Published in 2012

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Displaying works 241 - 260 of 260 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 journal article

Relationship between fecal hormone concentrations and reproductive success in captive pygmy rabbits (Brachylagus idahoensis)

JOURNAL OF MAMMALOGY, 93(3), 759–770.

By: C. Scarlata n, B. Elias*, J. Godwin n, R. Powell n, D. Shepherdson*, L. Shipley*, J. Brown*

author keywords: captive breeding; conception; fecal glucocorticoids; hormones; lactation; litter size; mating; progestagens; stress; reproduction
TL;DR: Investigating patterns of fecal progestagen and glucocorticoid excretion in females during mating, gestation, and lactation and identifying hormonal relationships to reproductive success found higher concentrations during the breeding season were associated with reduced conception rates and survival of subsequent litters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Production of prostaglandin E-2 in response to infection with modified vaccinia Ankara virus

VIROLOGY, 428(2), 146–155.

By: J. Pollara*, A. Spesock, D. Pickup, S. Laster* & I. Petty

author keywords: Poxvirus; Vaccine; Lipid mediator; Cyclooxygenase-2; Cytosolic phospholipase A(2); NF-kappa B
MeSH headings : Animals; Arachidonic Acid / metabolism; Cell Line; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Dinoprostone / metabolism; Humans; Mice; Vaccinia / enzymology; Vaccinia / metabolism; Vaccinia / virology; Vaccinia virus / genetics; Vaccinia virus / physiology; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR: In this study, PGE₂ production in vitro by cells infected with the poxvirus vaccine strain, modified vaccinia Ankara virus (MVA), is investigated and it is demonstrated that MVA induced the release of AA from infected cells, and this was, most unusually, independent of host cytosolic phospholipase A₁ activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Phenotypic Plasticity of the Drosophila Transcriptome

PLOS GENETICS, 8(3).

By: S. Zhou n, T. Campbell n, E. Stone n, T. Mackay n & R. Anholt n

MeSH headings : Animals; Cluster Analysis; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Gene Expression Regulation; Gene-Environment Interaction; Genetic Fitness; Genome, Insect; Phenotype; Transcriptome
TL;DR: This analysis suggests that a restricted environmentally responsive segment of the transcriptome preserves the balance between phenotypic plasticity and environmental canalization. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Joint genotyping on the fly: Identifying variation among a sequenced panel of inbred lines

GENOME RESEARCH, 22(5), 966–974.

By: E. Stone n

MeSH headings : Algorithms; Animals; Chromosome Mapping; Computer Simulation; Drosophila melanogaster / genetics; Genetic Variation; Genotyping Techniques / standards; Inbreeding; Likelihood Functions; Models, Genetic; Polymorphism, Single Nucleotide; Reference Standards; Sequence Analysis, DNA
TL;DR: This work presents the Joint Genotyper for Inbred Lines (JGIL) as a method for obtaining genotypes and identifying variation among a large panel of inbred strains or lines, and illustrates how JGIL is robust to moderate levels of error. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Fungal endophytes directly increase the competitive effects of an invasive forb

Ecology (Brooklyn, New York, N.Y.), 93(1), 3–8.

By: E. Aschehoug, K. Metlen, R. Callaway & G. Newcombe

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Environmental and Organismal Predictors of Intraspecific Variation in the Stoichiometry of a Neotropical Freshwater Fish

PLOS ONE, 7(3).

MeSH headings : Animals; Body Size; Ecosystem; Environment; Fishes / physiology; Fresh Water
TL;DR: It is suggested that spatial variability in elemental availability is more strongly correlated with organismal stoichiometry than organismal traits, and suggests that the stoichiometric of carnivores may not be completely buffered from environmental variability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Effect of Low-Head Lock-and-Dam Structures on Migration and Spawning of American Shad and Striped Bass in the Cape Fear River, North Carolina

TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY, 141(2), 402–413.

TL;DR: E egg distribution and stage of development suggested that most of the American shad spawning took place downstream from the lowermost structure, LD-1, while the probability of capturing a stage-1American shad egg was strongly dependent on water temperature and hour of egg coll... (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2012 review

Cultural traditions and the evolution of reproductive isolation: ecological speciation in killer whales?

[Review of ]. Biological Journal of the Linnean Society, 106(1), 1–17.

By: R. Riesch, L. Barrett-Lennard, G. Ellis, J. Ford & V. Deecke

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Proliferation of hydroelectric dams in the Andean Amazon and implications for Andes-Amazon connectivity

PLoS One, 7(4).

By: M. Finer & C. Jenkins

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice

MAMMALIAN GENOME, 23(5-6), 322–335.

By: J. Crowley*, Y. Kim*, J. Szatkiewicz*, A. Pratt*, C. Quackenbush*, D. Adkins*, E. Oord*, M. Bogue* ...

MeSH headings : Animals; Antipsychotic Agents / adverse effects; Basal Ganglia Diseases / chemically induced; Basal Ganglia Diseases / genetics; Basal Ganglia Diseases / physiopathology; Chromosome Mapping; Dyskinesia, Drug-Induced / genetics; Dyskinesia, Drug-Induced / physiopathology; Female; Genome-Wide Association Study; Humans; Male; Mice; Mice, Inbred A; Motor Activity; Polymorphism, Single Nucleotide
TL;DR: A validated mouse model was used for a systems genetics analysis geared toward detecting genetic predictors of TD in human patients and identified ~50 genes that are expected to have high prior probabilities for association with haloperidol-induced TD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems

DRUG AND CHEMICAL TOXICOLOGY, 35(3), 310–315.

author keywords: 2-aminoimidazole; adjuvant; biofilm; Caenorhabditis elegans; toxicity; Toxicity of 2-aminoimidazole; antibiofilm agents
MeSH headings : Adjuvants, Pharmaceutic / toxicity; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / toxicity; Biofilms / drug effects; Caenorhabditis elegans; Cell Line; Dose-Response Relationship, Drug; Environmental Exposure; Fertility / drug effects; Humans; Imidazoles / pharmacology; Imidazoles / toxicity; Keratinocytes / metabolism; Tetrazolium Salts; Thiazoles; Toxicity Tests
TL;DR: The most effective antibiofilm compound had significant effects when used in conjunction with several standard antibiotics against resistant bacteria and was found to maintain the same low level of toxicity as when acting alone, bolstering its candidacy for further testing as an adjuvant. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Computation of Neutron Multiplicity Statistics Using Deterministic Transport

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 59(2), 314–322.

author keywords: Coincidence techniques; neutron detectors; inverse problems; simulation
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Genetic estimates of population structure and dispersal in a benthic stream fish

Ecology of Freshwater Fish, 21(1), 75–86.

By: B. Lamphere & M. Blum

Source: NC State University Libraries
Added: August 6, 2018

2012 review

Endocrine Disrupters: A Review of Some Sources, Effects, and Mechanisms of Actions on Behaviour and Neuroendocrine Systems

[Review of ]. JOURNAL OF NEUROENDOCRINOLOGY, 24(1), 144–159.

By: C. Frye*, E. Bo*, G. Calamandrei*, L. Calza*, F. Dessi-Fulgheri, M. Fernandez*, L. Fusani*, O. Kah* ...

author keywords: xenoestrogens; dichloro diphenyl trichloroethane; methoxychlor; biocides; tributyltin; bisphenol A; diethylstilbestrol; ethinylestradiol; phytoestrogens; aryl hydrocarbon receptor; the peroxisome proliferator-activated receptor; retinoid X receptor
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds; Brain / drug effects; Endocrine Disruptors / pharmacology; Environmental Pollutants / pharmacology; Humans; Phenols / pharmacology; Phytoestrogens / pharmacology; Puberty / drug effects; Reproduction / drug effects
TL;DR: EDCs, from varied sources, may have organisational effects during development and/or activational effects in adulthood that influence sexually‐dimorphic, reproductively‐relevant processes or other functions, by mimicking, antagonising or altering steroidal actions. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Differential expression and biological activity of two piscidin paralogues and a novel splice variant in Atlantic cod (Gadus morhua L.)

Fish & Shellfish Immunology, 32(3), 396–406.

By: J. Ruangsri, S. Salger, C. Caipang, V. Kiron & J. Fernandes

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Who likes it hot? A global analysis of the climatic, ecological, and evolutionary determinants of warming tolerance in ants

Global Change Biology, 18(2), 448–456.

By: S. Diamond, D. Sorger, J. Hulcr, S. Pelini, I. Del Toro, C. Hirsch, E. Oberg, R. Dunn

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer

CANCER BIOLOGY & THERAPY, 13(3), 130–137.

By: E. Rinella*, E. Bankaitis* & D. Threadgill n

author keywords: colon cancer; EGFR; calcium; mouse models; AG1478; therapy; toxicity
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Antineoplastic Agents / toxicity; Azoxymethane; Calcium / pharmacology; Calcium / therapeutic use; Calcium / toxicity; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Colonic Neoplasms / chemically induced; Colonic Neoplasms / drug therapy; Colonic Neoplasms / pathology; Dietary Supplements; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors / antagonists & inhibitors; Female; Humans; MAP Kinase Signaling System / drug effects; Male; Mice; Mice, Inbred C57BL; Quinazolines / pharmacology; Quinazolines / therapeutic use; Quinazolines / toxicity; Random Allocation; Tumor Burden / drug effects; Tyrphostins / pharmacology; Tyrphostins / therapeutic use; Tyrphostins / toxicity
TL;DR: Calcium supplementation combined with pharmacologic blockade of EGFR results in an additive effect on tumor growth inhibition in all models and the combined use of dietary calcium supplementation and EGFR inhibitors also resulted in elevated toxicity suggesting that careful consideration be given when combining dietary supplements with prescribed cancer therapies. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 review

A conceptual model for the origin of worker behaviour and adaptation of eusociality

[Review of ]. JOURNAL OF EVOLUTIONARY BIOLOGY, 25(1), 1–19.

By: J. Hunt n

author keywords: altruism; Baldwin effect; conceptual model; exaptation; genetic assimilation; inclusive fitness; kin selection; multilevel selection; phenotypic accommodation; Polistes
MeSH headings : Adaptation, Biological; Altruism; Animals; Behavior, Animal; Biological Evolution; Genetic Fitness; Models, Biological; Phenotype; Phylogeny; Selection, Genetic; Social Behavior; Wasps / genetics
TL;DR: Roles of behavioural flexibility and developmental plasticity in the evolutionary process equal or exceed those of genotype and components of multilevel selection vary across levels of eusociality. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 article

On the scent of pleiotropy

Singh, N. D., & Shaw, K. L. (2012, January 3). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 109, pp. 5–6.

By: N. Singh n & K. Shaw*

MeSH headings : Animals; Drosophila Proteins / genetics; Drosophila melanogaster / enzymology; Drosophila melanogaster / genetics; Fatty Acid Desaturases / genetics; Female; Gene Expression Regulation, Enzymologic; Male; Nervous System / enzymology; Perception / physiology; Sex Attractants / metabolism
TL;DR: The work presented in PNAS by Bousquet et al. (4) builds the best case to date for genetic coupling between signaler and receiver traits in sexual communication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

TCDD Disrupts Hypural Skeletogenesis during Medaka Embryonic Development

TOXICOLOGICAL SCIENCES, 125(1), 91–104.

By: W. Dong n, D. Hinton* & S. Kullman n

author keywords: medaka; dioxin; cartilage; skeletogenesis; aquatic toxicology
MeSH headings : Animals; Cartilage / abnormalities; Cartilage / drug effects; Cartilage / embryology; Cartilage / ultrastructure; Cell Differentiation / drug effects; Cell Proliferation / drug effects; Chondrocytes / drug effects; Chondrocytes / ultrastructure; Collagen Type II / genetics; Dose-Response Relationship, Drug; Embryo, Nonmammalian / abnormalities; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / pathology; Gene Expression / drug effects; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / ultrastructure; Microscopy, Electron, Transmission; Musculoskeletal Abnormalities / chemically induced; Musculoskeletal Abnormalities / embryology; Musculoskeletal Abnormalities / pathology; Oryzias / abnormalities; Oryzias / embryology; Osteogenesis / drug effects; Polychlorinated Dibenzodioxins / toxicity; Real-Time Polymerase Chain Reaction
TL;DR: It is illustrated that TCDD impacts terminal differentiation and growth of cartilage and bone in axial structures not likely derived from neural crest progenitors in medaka hypurals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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