Works Published in 2022
Displaying works 41 - 60 of 229 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2022 journal article
Prescribed fire in longleaf pine ecosystems: fire managers' perspectives on priorities, constraints, and future prospects
FIRE ECOLOGY, 18(1).
author keywords: Longleaf pine; Prescribed fire; Compound stressors; Burn windows; Conservation goals; Climate change
fireecology.springeropen.com (publisher PDF)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: December 12, 2022
2022 journal article
Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure
TOXICS, 10(12).
author keywords: gene-environment interaction; chemical risk-assessment; zebrafish behavior; toxicity screening
TL;DR:
It is demonstrated how standing genetic variation in a heterogeneous population such as the authors' can be leveraged to test for potential GxE by showing evidence that heritable genetics are directly affecting gene expression and behavioral susceptibility of individuals to PFHxA exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 10, 2022
2022 article
Assessing the Nucleotide-Level Impact of Spaceflight Stress using RNA-Sequencing Data
Knight, M. S., Doherty, C. J., & Nielsen, D. M. (2022, December 2).
TL;DR:
GeneLab data is used to examine DNA sequence variants linked to spaceflight stress exposure and provides a baseline for the types of mutations that could be detected, demonstrating that RNA-Seq data is a useful resource for evaluating DNA damage from spaceflight.
(via Semantic Scholar)
Source: ORCID
Added: December 7, 2022
2022 journal article
The acclimatory response of the mayfly Neocloeon triangulifer to dilute conditions is linked to the plasticity of sodium transport
author keywords: mayfly; dilute; ion transport; acclimation; life history; sodium
MeSH headings : Acclimatization; Animals; Ephemeroptera / physiology; Fresh Water; Gills; Ions; Salinity; Sodium; Water Pollutants, Chemical
TL;DR:
A physiological affinity for dilute conditions in this emerging mayfly model is shown, as nymphs acclimated to their dilute exposures by increasing their rates of Na uptake and were able to maintain a relatively narrow range of uptake rates across all treatments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: December 5, 2022
2022 article
Genome-wide meta-analysis identifies novel maternal risk variants and enables polygenic prediction of preeclampsia and gestational hypertension
Honigberg, M. C., Truong, B., Khan, R. R., Xiao, B., Bhatta, L., Vy, T. H., … Natarajan, P. (2022, December 1).
TL;DR:
Findings provide mechanistic insights into the hypertensive disorders of pregnancy and advance pregnancy risk stratification as identified loci highlight the role of natriuretic peptide signaling, angiogenesis, renal glomerular function, trophoblast development, and immune dysregulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 2, 2022
2022 journal article
A Double Penalty Model for Ensemble Learning
MATHEMATICS, 10(23).
author keywords: double penalty model; interpretability; partially linear model; separability
TL;DR:
By considering ensemble learning for two learning ensemble components as a double penalty model, this work provides a framework to better understand the relative convergence and identifiability of the two components.
(via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 1, 2022
2022 book
Ancient DNA
Source: Crossref
Added: November 21, 2022
2022 article
A standardized procedure for quantitative evaluation of residual viral activity on antiviral treated textiles
Wang, Z., Amanah, A. Y., Ali, K. M., Payne, L. C., Kisthardt, S., Scholle, F., … Gluck, J. M. (2022, November 2). TEXTILE RESEARCH JOURNAL.
author keywords: SARS-CoV-2; antiviral textiles; Tissue Culture Infectious Dose 50
TL;DR:
This pilot study aims to develop and refine a standardized protocol to quantitatively evaluate residual viral activity on antiviral textiles and used HCoV-229E and Huh-7 human liver cancer cells for this investigation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 21, 2022
2022 article
Gender Stereotypes and Peer Selection in STEM Domains Among Children and Adolescents
McGuire, L., Hoffman, A. J., Mulvey, K. L., Hartstone-Rose, A., Winterbottom, M., Joy, A., … Rutland, A. (2022, November 4). SEX ROLES, Vol. 11.
author keywords: STEM stereotypes; Gender stereotypes; Peer selection; Social identity
UN Sustainable Development Goal Categories
4. Quality Education
(OpenAlex)
10. Reduced Inequalities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 21, 2022
2022 article
Promoting Diverse Youth's Career Development through Informal Science Learning: The Role of Inclusivity and Belonging
Zhao, M., Mathews, C. J., Mulvey, K. L., Hartstone-Rose, A., McGuire, L., Hoffman, A. J., … Rutland, A. (2022, November 7). JOURNAL OF YOUTH AND ADOLESCENCE, Vol. 11.
author keywords: Inclusivity; Inclusion; Social identity; Belonging; Career development; Informal science
MeSH headings : Female; Humans; Adolescent; United States; Infant; Male; Ethnicity; Gender Identity; Social Identification; United Kingdom
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 21, 2022
2022 journal article
Pleiotropic modifiers of age-related diabetes and neonatal intestinal obstruction in cystic fibrosis
AMERICAN JOURNAL OF HUMAN GENETICS, 109(10), 1894–1908.
MeSH headings : Cystic Fibrosis / complications; Cystic Fibrosis / genetics; Cystic Fibrosis Transmembrane Conductance Regulator / genetics; Diabetes Mellitus / genetics; Genome-Wide Association Study; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Obstruction / complications; Intestinal Obstruction / genetics
TL;DR:
Different loci modify risk of CFRD and MI; however, a subset exhibit pleiotropic effects indicating etiologic and mechanistic overlap between these two otherwise distinct complications of CF.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 21, 2022
2022 journal article
A cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes
AMERICAN JOURNAL OF HUMAN GENETICS, 109(10), 1814–1827.
MeSH headings : Alleles; Animals; Brain / metabolism; Chromosome Mapping; Humans; Ischemic Stroke; Mice; Vesicular Transport Proteins / genetics; rab GTP-Binding Proteins / genetics; rab GTP-Binding Proteins / metabolism
TL;DR:
This work established an in vivo evaluation platform in mice by using adeno-associated virus (AAV) gene replacement and verified that both mouse and human RABEP2 rescue the mouse Rabep2 knockout ischemic stroke volume and collateral vessel phenotypes, and chose four coding variants from the human population that are predicted by multiple in silico algorithms to be damaging to RAB EP2 function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 21, 2022
2022 journal article
C3NA: correlation and consensus-based cross-taxonomy network analysis for compositional microbial data
BMC BIOINFORMATICS, 23(1).
author keywords: Co-occurrence network analysis; Microbiome; R package; Consensus clustering; Module preservation analysis
MeSH headings : Phylogeny; Consensus
TL;DR:
C3NA is presented, a user-friendly R package for investigating compositional microbial sequencing data to identify and compare co-occurrence patterns across different taxonomic levels and discovered clusters of study and disease-dependent taxa that overlap with known functional taxa studied by other discovery studies and differential abundance analyses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 21, 2022
2022 journal article
Hybridization order is not the driving factor behind biases in duplicate gene losses among the hexaploid Solanaceae
author keywords: Solanaceae; polyploidy; biased fractionation; hexaploidy; repetitive elements
MeSH headings : Genes, Duplicate; Polyploidy; Solanaceae / genetics; Evolution, Molecular; Brassicaceae / genetics; Bias; Genome, Plant
TL;DR:
Whether the distribution of repetitive elements in these genomes can explain the biases in gene losses is explored, but while the signals found are broadly consistent with a role for high RE density in driving gene losses, the REs turn over so quickly that little signal of the RE condition at the time of paleopolyploidy is extant in the modern genomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 14, 2022
2022 journal article
Endogenous Diurnal Patterns of Adrenal and Gonadal Hormones During a 24-Hour Constant Routine After Simulated Shift Work
JOURNAL OF THE ENDOCRINE SOCIETY, 6(12).
author keywords: circadian misalignment; healthy young adults; internal desynchrony; reproductive health; sex steroids
TL;DR:
Experimental circadian misalignment had minimal effects on steroidogenesis and adrenal steroids, but not gonadal hormones, showed endogenous circadian regulation robust to prior shift schedule, which may predispose night-shift workers to metabolic ill health.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 14, 2022
2022 journal article
CIRCADIAN DYSREGULATION OF HUMAN DNA REPAIR GENES AND ELEVATED DNA DAMAGE IN SIMULATED NIGHT SHIFT SCHEDULE
Sleep. https://publons.com/wos-op/publon/54906417/
Contributors: H. Van Dongen, B. Koritala, K. Porter, O. Arshad, R. Gajula, H. Mitchell, T. Arman, M. Manjanatha
Source: ORCID
Added: November 14, 2022
2022 journal article
Leveraging a natural murine meiotic drive to suppress invasive populations
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(46).
author keywords: genetic biocontrol; gene drive; invasive rodents; conservation; modeling
MeSH headings : Mice; Female; Animals; Biodiversity; Gene Drive Technology; Rodentia; Genetics, Population; Clustered Regularly Interspaced Short Palindromic Repeats
TL;DR:
Modelling of realistic parameter values indicates that tCRISPR can eradicate an island population of 200,000 mice while the unmodified t haplotype fails under the same conditions, and is the first example of a feasible gene drive system for invasive alien rodent population control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 9, 2022
2022 article
The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease
Riegl, S. D., Starnes, C., Jima, D. D., Baptissart, M., Diehl, A. M., Belcher, S. M., & Cowley, M. (2022, October 6). TOXICOLOGICAL SCIENCES, Vol. 10.
author keywords: nonalcoholic fatty liver disease; developmental toxicology; epigenetics; cadmium; genomic imprinting; developmental programming
MeSH headings : Mice; Animals; Non-alcoholic Fatty Liver Disease / genetics; Non-alcoholic Fatty Liver Disease / metabolism; Cadmium; Cadmium Chloride / toxicity; PPAR gamma; Liver / metabolism; Fibrosis
TL;DR:
It is demonstrated that developmental Cd exposure is sufficient to program NAFLD in later life, and Zac1 and the IGN are established as key regulators of prosteatotic and profibrotic pathways, two of the major pathological hallmarks ofNAFLD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 7, 2022
2022 article
Life-history stage and the population genetics of the tiger mosquito Aedes albopictus at a fine spatial scale
Reed, E. M. X., Reiskind, M. H., & Reiskind, M. O. B. (2022, October 27). MEDICAL AND VETERINARY ENTOMOLOGY, Vol. 10.
Contributors: M. Reiskind n
author keywords: Aedes albopictus; invasive species; life stage; mosquito; population genetics
MeSH headings : Animals; Aedes / genetics; Mosquito Vectors; Genetics, Population; Larva / genetics; Pupa / genetics
TL;DR:
Examining population genomic patterns of egg and adult A. albopictus at five sites in Wake County, North Carolina, USA found that the level of genetic diversity and connectivity between sites varied between adults and eggs, which warrants further study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: ORCID, Web Of Science
Added: November 1, 2022
2022 review
Racial disparities in liver cancer: Evidence for a role of environmental contaminants and the epigenome
[Review of ]. FRONTIERS IN ONCOLOGY, 12.
author keywords: liver cancer; race; epigenetic; contaminants; epigenome
TL;DR:
The hypothesis that epigenetic mediators may provide biomarkers for early detection to support interventions that reduce disparities is discussed and the paucity of mechanistic insights impedes prevention efforts is evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: October 31, 2022
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