Works Published in 2019

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Displaying works 201 - 220 of 278 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 journal article

Evaluation of a multi-agent chemotherapy protocol combining dexamethasone, melphalan, actinomycin D, and cytarabine for the treatment of resistant canine non-Hodgkin high-grade lymphomas: a single centre's experience

VETERINARY AND COMPARATIVE ONCOLOGY, 17(2), 165–173.

By: K. Smallwood*, J. Tanis*, I. Grant*, L. Blackwood*, D. Killick*, I. Amores-Fuster*, J. Elliott*, A. Mas* ...

author keywords: actinomycin-D; canine lymphoma; chemotherapy; DMAC; dog; melphalan; rescue; resistant lymphoma
MeSH headings : Animals; Antibiotics, Antineoplastic / pharmacology; Antimetabolites, Antineoplastic / pharmacology; Antineoplastic Agents / pharmacology; Antineoplastic Agents, Alkylating / pharmacology; Antineoplastic Agents, Hormonal / pharmacology; Antineoplastic Combined Chemotherapy Protocols / pharmacology; Cohort Studies; Cytarabine / pharmacology; Dactinomycin / pharmacology; Databases, Factual; Dexamethasone / pharmacology; Dog Diseases / drug therapy; Dogs; Female; Kaplan-Meier Estimate; Lymphoma, Non-Hodgkin / drug therapy; Lymphoma, Non-Hodgkin / veterinary; Male; Melphalan / pharmacology; Neoplasm Recurrence, Local / drug therapy; Neutropenia / veterinary; Remission Induction; Schools, Veterinary; Thrombocytopenia / veterinary; Treatment Outcome; United Kingdom
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 13, 2019

2019 journal article

Multicentre, blinded, randomised clinical trial comparing the use of flunixin meglumine with firocoxib in horses with small intestinal strangulating obstruction

EQUINE VETERINARY JOURNAL, 51(3), 329–335.

By: A. Ziegler n, C. Freeman n, C. Fogle n, M. Burke n, J. Davis*, V. Cook*, L. Southwood*, A. Blikslager n

author keywords: horse; colic; endotoxaemia; flunixin meglumine; firocoxib; clinical study
MeSH headings : 4-Butyrolactone / administration & dosage; 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / therapeutic use; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / therapeutic use; Female; Horse Diseases / drug therapy; Horses; Intestinal Obstruction / complications; Intestinal Obstruction / veterinary; Male; Pain, Postoperative / drug therapy; Pain, Postoperative / veterinary; Random Allocation; Sulfones / administration & dosage; Sulfones / therapeutic use
TL;DR: Treatment of post-surgical SISO horses with firocoxib (COX-2 selective) would reduce the signs of endotoxaemia to a greater extent than flunixin meglumine (nonselective COX inhibitor) while continuing to provide similar levels of pain control. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 6, 2019

2019 journal article

The effect of a surgical safety checklist on complication rates associated with permanent transvenous pacemaker implantation in dogs

JOURNAL OF VETERINARY CARDIOLOGY, 22, 72–83.

By: J. Ward*, A. McLaughlin n, R. Burzette* & B. Keene n

author keywords: Canine; Atrioventricular block; Heart block; Bradycardia
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bradycardia / surgery; Bradycardia / therapy; Bradycardia / veterinary; Checklist / statistics & numerical data; Dog Diseases / surgery; Dog Diseases / therapy; Dogs; Hospitals, Animal / statistics & numerical data; North Carolina; Pacemaker, Artificial / veterinary; Postoperative Complications / mortality; Postoperative Complications / prevention & control; Postoperative Complications / veterinary; Retrospective Studies; Treatment Outcome
TL;DR: Use of an SSC was associated with a decrease in the major complication rate and an increase in compliance with antibiotic protocols during pacemaker implantation in dogs, and results of this study support the use of the SSC in veterinary cardiology procedures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
4. Quality Education (Web of Science)
Source: Web Of Science
Added: May 6, 2019

2019 journal article

Pharmacokinetics and ex vivo anti-inflammatory effects of oral misoprostol in horses

EQUINE VETERINARY JOURNAL, 51(3), 415–421.

author keywords: horse; leucocyte; E prostanoid receptor agonist; pharmacokinetics; inflammation; tumour necrosis factor-
MeSH headings : Abortifacient Agents, Nonsteroidal / administration & dosage; Abortifacient Agents, Nonsteroidal / pharmacokinetics; Administration, Oral; Animals; Area Under Curve; Cells, Cultured; Horse Diseases / drug therapy; Horse Diseases / metabolism; Horses / blood; Horses / metabolism; Inflammation / drug therapy; Inflammation / metabolism; Inflammation / veterinary; Leukocytes / drug effects; Leukocytes / metabolism; Misoprostol / administration & dosage; Misoprostol / pharmacokinetics
TL;DR: Misoprostol is rapidly absorbed following oral administration in horses, and a single 5 μg/kg dose had no significant inhibitory effect on ex vivo LPS‐stimulated TNFα mRNA production in leucocytes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: May 6, 2019

2019 journal article

Letter to the Editor: Bias in statistics or bias in equine veterinary medicine?

Equine Veterinary Journal, 51(3), 423–423.

By: A. Ziegler n, C. Fogle n, M. Burke n & A. Blikslager n

MeSH headings : 4-Butyrolactone / analogs & derivatives; Animals; Clonixin / analogs & derivatives; Horses; Sulfones
TL;DR: It is proposed that validating a trend towards improved survival in horses treated with firocoxib would require additional studies with greater numbers of horses and likely modification of the study design to include preoperative drug randomisation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: May 6, 2019

2019 journal article

Thyroid Hormone and Thyrotropin Concentrations and Responses to Thyrotropin-Stimulating Hormone in Horses with PPID Compared with Age-Matched Normal Horses

JOURNAL OF EQUINE VETERINARY SCIENCE, 75, 35–40.

By: B. Breuhaus n

author keywords: Pituitary pars intermedia dysfunction; Horse; Thyroid hormone; Thyrotropin; Thyrotropin-releasing hormone
MeSH headings : Animals; Equidae; Horses; Pituitary Diseases / veterinary; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone
TL;DR: Normal serum thyroid hormone and TSH concentration responses to exogenous TRH administration support the theory that increased glucocorticoid activity in horses with PPID may exert prolonged tonic suppression, but not complete inhibition, of TRH and subsequent TSH release, similar to what has been observed in other species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2019

2019 journal article

Retraction mechanics of Finochietto-style self-retaining thoracic retractors

BIOMEDICAL ENGINEERING ONLINE, 18.

By: G. Chanoit*, C. Pell*, G. Bolotin*, G. Buckner n, J. Williams* & H. Crenshaw*

author keywords: Retraction; Thoracotomy; Sternotomy; Finochietto; Rib fracture; Force relaxation
MeSH headings : Animals; Female; Mechanical Phenomena; Swine; Thoracotomy / instrumentation; Weight-Bearing
TL;DR: The Finochietto-style retractor can generate large forces and some aspects of its design increase the probability of tissue trauma, and mechanical analyses revealed that arm motion is a non-linear function of handle rotation. (via Semantic Scholar)
Source: Web Of Science
Added: April 29, 2019

2019 journal article

Are Geckos Paratenic Hosts for Caribbean Island Acanthocephalans? Evidence from Gonatodes antillensis and a Global Review of Squamate Reptiles Acting as Transport Hosts

BULLETIN OF THE PEABODY MUSEUM OF NATURAL HISTORY, 60(1), 55–79.

author keywords: Acanthocephala; intestinal helminths; cats; parasite; trophic transmission; mammals; birds; host-parasite interactions; vector species
TL;DR: Evidence is found that the ability of squamate reptiles to act as transport hosts is a pervasive feature across their Tree of Life, suggesting that these animals may serve as important vectors for transporting parasites between intermediate and definitive hosts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 29, 2019

2019 journal article

ACVIM consensus statement on the diagnosis of immune-mediated hemolytic anemia in dogs and cats

JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(2), 313–334.

author keywords: comorbidity; Delphi survey; direct antiglobulin test; erythrocyte; evidence; flow cytometry; hemolysis; iceberg model; spherocyte; veterinary and comparative clinical immunology society
MeSH headings : Anemia, Hemolytic, Autoimmune / diagnosis; Anemia, Hemolytic, Autoimmune / etiology; Anemia, Hemolytic, Autoimmune / veterinary; Animals; Cat Diseases / diagnosis; Cat Diseases / etiology; Cats; Comorbidity; Consensus; Dog Diseases / diagnosis; Dog Diseases / etiology; Dogs; Societies, Veterinary
TL;DR: Clinical guidelines for diagnosis of, and underlying disease screening for, IMHA in dogs and cats are provided, which should be implemented with consideration of animal, owner, and geographical factors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 22, 2019

2019 journal article

Baseline plasma thromboelastography in Kemp’s ridley (Lepidochelys kempii), green (Chelonia mydas) and loggerhead (Caretta caretta) sea turtles and its use to diagnose coagulopathies in cold-stunned Kemp’s ridley and green sea turtles

Journal of Zoo and Wildlife Medicine, 50(1), 62.

By: A. Barratclough*, K. Tuxbury*, R. Hanel n, N. Stacy*, L. Ruterbories n, E. Christiansen*, C. Harms n

author keywords: Coagulation; coagulopathy; cold stunned; sea turtle; thromboelastography
MeSH headings : Animals; Cold Temperature / adverse effects; Hemostasis; Plasma / chemistry; Reference Values; Species Specificity; Thrombelastography / veterinary; Turtles / blood
TL;DR: Findings indicate that cold stunning may cause disorders in hemostasis that can contribute to the severity of the condition and early diagnosis of coagulopathies in the clinical assessment of a cold-stunned sea turtle may influence the treatment approach and clinical outcome of the case. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 22, 2019

2019 review

The renin-angiotensin-aldosterone system and its suppression

[Review of ]. JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(2), 363–382.

author keywords: angiotensin converting enzyme inhibitor; angiotensin receptor blocker; chronic kidney disease; heart failure; mineralocorticoid receptor blocker; proteinuric kidney disease; systemic hypertension
MeSH headings : Aldosterone / metabolism; Angiotensin II / metabolism; Angiotensin Receptor Antagonists / therapeutic use; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Cat Diseases / drug therapy; Cat Diseases / physiopathology; Cats; Dog Diseases / drug therapy; Dog Diseases / physiopathology; Dogs; Heart Failure / veterinary; Hypertension / veterinary; Kidney Diseases / veterinary; Mineralocorticoid Receptor Antagonists / therapeutic use; Renin-Angiotensin System / drug effects; Renin-Angiotensin System / physiology
TL;DR: This review focuses on updates in the understanding of the RAAS and the pathophysiology of AngII and aldosterone excess, reviewing what is known about its suppression in cardiovascular and renal diseases, especially in the cat and dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 22, 2019

2019 journal article

Prognostic value of fluorine(18) flourodeoxyglucose positron emission tomography/computed tomography in dogs with appendicular osteosarcoma

JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(2), 820–826.

author keywords: avidity; cancer; canine; MST; SUVmax
MeSH headings : Animals; Bone Neoplasms / diagnostic imaging; Bone Neoplasms / therapy; Bone Neoplasms / veterinary; Dogs; Extremities; Fluorodeoxyglucose F18; Osteosarcoma / diagnostic imaging; Osteosarcoma / therapy; Osteosarcoma / veterinary; Positron Emission Tomography Computed Tomography / veterinary; Prognosis; Progression-Free Survival; Radiopharmaceuticals; Retrospective Studies
TL;DR: Maximum standard uptake value as measured via 18F‐FDG PET/CT is significantly associated with survival in dogs with appendicular OSA with a high SUVmax being an indicator of a negative prognosis. (via Semantic Scholar)
Source: Web Of Science
Added: April 22, 2019

2019 journal article

Enrofloxacin Pharmacokinetics and Sampling Techniques in California Sea Hares (Aplysia californica)

Journal of the American Association for Laboratory Animal Science, 58(2), 231–234.

By: S. Mason n, M. Papich n, M. Schmale*, C. Harms n & S. Davis*

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Aplysia / metabolism; Chromatography, High Pressure Liquid; Enrofloxacin / administration & dosage; Enrofloxacin / pharmacokinetics; Laboratory Animal Science
TL;DR: Hemocoel injection appears to be an effective way to administer enrofloxacin to Aplysia and reach clinically relevant concentrations, and reached therapeutic target concentrations in A. californica when dosed according to the regimen described in the current report. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: April 22, 2019

2019 journal article

Clinicopathological findings in 41 dogs (2008‐2018) naturally infected with Ehrlichia ewingii

Journal of Veterinary Internal Medicine, 33(2), 618–629.

By: B. Qurollo n, J. Buch*, R. Chandrashekar*, M. Beall*, E. Breitschwerdt n, C. Yancey*, A. Caudill n, A. Comyn n

author keywords: canine; granulocytic ehrlichiosis; tick borne
MeSH headings : Animals; Antibodies, Bacterial / blood; Blood Cell Count / veterinary; Borrelia burgdorferi / immunology; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Ehrlichia / immunology; Ehrlichia canis / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Female; Male; Retrospective Studies; Serologic Tests / veterinary
TL;DR: Renal disease, IMHA, proteinuria, neutrophilia, abnormal lymphocytes, and increased liver enzyme activities were common in this group of E. ewingii‐infected dogs and studies are needed to determine if E. Ewingii contributes to comorbidities or is a precipitating factor in clinical syndromes in persistently infected dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 22, 2019

2019 journal article

TISSUE ENZYME ACTIVITIES IN FREE-LIVING EASTERN BOX TURTLES (TERRAPENE CAROLINA CAROLINA)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 50(1), 45–54.

By: L. Adamovicz*, J. Griffioen n, A. Cerreta n, G. Lewbart n & M. Allender*

author keywords: biochemistry enzyme activity; eastern box turtle Terrapene carolina carolina; reptile; tissue specificity
MeSH headings : Animal Testing Alternatives; Animals; Enzymes / metabolism; Female; Male; Organ Specificity; Turtles / metabolism
TL;DR: Tissue specificity of six biochemical enzymes evaluated in box turtles was evaluated, and AST was relatively nonspecific, with significantly higher activity in the cardiac muscle, liver, kidney, skeletal muscle, and gallbladder compared to other tissues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 22, 2019

2019 journal article

Response and outcome following toceranib phosphate treatment for stage four anal sac apocrine gland adenocarcinoma in dogs: 15 cases (2013-2017)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 254(8), 960–966.

By: J. Elliott*

MeSH headings : Adenocarcinoma / veterinary; Anal Sacs; Animals; Apocrine Glands; Dog Diseases; Dogs; Indoles; Pyrroles; Quality of Life; Retrospective Studies; Treatment Outcome
TL;DR: Results of the present study indicated that dogs with stage 4 ASAGA treated with toceranib had improved outcomes, compared with outcomes previously reported for dogs with ASAGA that had received non-tyrosine kinase inhibitor treatments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 22, 2019

2019 journal article

IMMERSION IN TRICAINE METHANESULFONATE (MS-222) IS NOT SUFFICIENT FOR EUTHANASIA OF SMOKEY JUNGLE FROGS (LEPTODACTYLUS PENTADACTYLUS)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 50(1), 89–95.

author keywords: Animal welfare; Euthanasia; Leptodactylus petuadactylus; MS-222; Smokey Jungle Frog; Tricaine methanesulfonate
MeSH headings : Aminobenzoates / therapeutic use; Anesthetics / therapeutic use; Animals; Anura / physiology; Dose-Response Relationship, Drug; Euthanasia, Animal / methods; Immersion
TL;DR: Although death was achieved in 17 of 18 frogs, given the repeated events of regained consciousness, MS-222 immersion when used at concentrations ≤10 g/L did not result in rapid and distress-free death and is not sufficient for humane euthanasia in this species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: April 22, 2019

2019 journal article

2-Phenoxyethanol (2-PE) and tricaine methanesulfonate (MS-222) immersion anesthesia of American horseshoe crabs (Limulus polyphemus)

Journal of Zoo and Wildlife Medicine, 50(1), 96–106.

MeSH headings : Aminobenzoates / adverse effects; Anesthesia / methods; Anesthesia / veterinary; Anesthetics / adverse effects; Animals; Ethylene Glycols / adverse effects; Female; Horseshoe Crabs / drug effects; Horseshoe Crabs / physiology; Immersion; Male; North Carolina; Random Allocation
TL;DR: 2-PE provided a subjectively more reliable and smoother anesthesia compared to MS-222, and provided effective anesthesia with clinically useful induction and recovery times. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 22, 2019

2019 journal article

Incidence and risk factors associated with development of clinical cardiotoxicity in dogs receiving doxorubicin

Journal of Veterinary Internal Medicine, 33(2), 783–791.

By: B. Hallman n, M. Hauck n, L. Williams*, P. Hess n & S. Suter n

author keywords: canine; cardiology; cardiomyopathy; chemotherapy; echocardiography; oncology
MeSH headings : Animals; Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / adverse effects; Antibiotics, Antineoplastic / therapeutic use; Body Weight; Cardiomyopathy, Dilated / veterinary; Cardiotoxicity / veterinary; Dog Diseases / drug therapy; Dogs; Doxorubicin / administration & dosage; Doxorubicin / adverse effects; Doxorubicin / therapeutic use; Female; Heart Diseases / chemically induced; Heart Diseases / veterinary; Incidence; Male; Neoplasms / drug therapy; Neoplasms / veterinary; Retrospective Studies; Risk Factors
TL;DR: Overall, the incidence of clinical DOX‐induced cardiotoxicity is low, but Boxers and other breeds at high risk for dilated cardiomyopathy may be at an increased risk. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 22, 2019

2019 journal article

EVALUATION OF EUTHANASIA OF MOON JELLYFISH (AURELIA AURITA) USING SIMPLE SALT SOLUTIONS

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 50(1), 123–126.

By: M. Doerr n & M. Stoskopf n

author keywords: Aurelia aurita; euthanasia; invertebrate; jellyfish; MgCl2
MeSH headings : Animals; Euthanasia, Animal / methods; Ions / administration & dosage; Ions / pharmacology; Magnesium Chloride / administration & dosage; Magnesium Chloride / pharmacology; Magnesium Sulfate / administration & dosage; Magnesium Sulfate / pharmacology; Potassium Chloride / administration & dosage; Potassium Chloride / pharmacology; Scyphozoa / drug effects; Scyphozoa / physiology
TL;DR: A rolling study design evaluated potassium chloride, magnesium chloride, and magnesium sulfate as potential ion-based euthanasia methods for moon jellyfish destined for metabolomic analysis by NMR spectroscopy and found that MgSO4 at the doses tested resulted in abnormal behavior and failed to provide rapid euthanasia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 22, 2019

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