Works Published in 2001
Displaying works 21 - 40 of 55 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2001 journal article
Low Exposure Concentration Effects of Methoprene on Endocrine-Regulated Processes in the Crustacean Daphnia magna
Toxicological Sciences, 62(2), 268–273.
author keywords: methoprene; daphnid; crustacea; endocrine disruption; methyl farnesoate
MeSH headings : Animals; Daphnia / drug effects; Daphnia / growth & development; Daphnia / physiology; Dose-Response Relationship, Drug; Endocrine Glands / drug effects; Endocrine Glands / physiology; Fertility; Juvenile Hormones / toxicity; Methoprene / toxicity; Reproduction
TL;DR:
It is demonstrated that methoprene elicits significant toxicity to endocrine-related processes in the 5-50 nM concentration range, and molting and reproduction were impacted at significantly lower meethoprene concentrations, with a distinct concentration response and a threshold of < or =0.2 nM.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 28, 2020
2001 journal article
AGRICULTURAL EXPOSURE HISTORY AMONG AFRICAN-AMERICAN FARMERS IN GEORGIA
Journal of Toxicology and Environmental Health, Part A, 63(4), 237–241.
Contributors: J. Hoppin* , J. Guzman*, P. Tolbert* & E. Flagg*
MeSH headings : Adult; Black or African American; Aged; Aged, 80 and over; Agricultural Workers' Diseases / epidemiology; Data Collection; Georgia / epidemiology; Humans; Male; Middle Aged; Occupational Exposure / statistics & numerical data; Pesticides; Surveys and Questionnaires
TL;DR:
A pilot study was conducted to explore the breadth and diversity of farming practices over time among African-American farmers in Georgia whose exposures may differ in important ways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2001 journal article
Cross-species and interassay comparisons of phytoestrogen action.
Environmental Health Perspectives, 109(suppl 1), 5–20.
MeSH headings : Animals; Biological Assay / methods; Bone Density / drug effects; Breast / drug effects; Breast / pathology; Cell Division / drug effects; Diet; Dose-Response Relationship, Drug; Endocrine System / drug effects; Estrogens / agonists; Humans; Hypothalamo-Hypophyseal System / drug effects; Plant Growth Regulators / pharmacology; Urogenital System / drug effects; Urogenital System / pathology
TL;DR:
The similarity of reported proliferative and antiproliferative doses illustrates the need for fuller examination of dose-response relationships and multiple end points in assessing phytoestrogen actions.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2001 journal article
Coumestrol Antagonizes Neuroendocrine Actions of Estrogen via the Estrogen Receptor α
Experimental Biology and Medicine, 226(4), 301–306.
author keywords: phytoestrogen; progesterone receptor; luteinizing hormone; nutrition; estrogen receptor beta
MeSH headings : Animals; Brain / drug effects; Brain / metabolism; Coumestrol / administration & dosage; Coumestrol / pharmacology; Drug Evaluation, Preclinical; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogen Receptor alpha; Estrogens, Non-Steroidal / pharmacology; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Luteinizing Hormone / blood; Mice; Mice, Knockout; Ovariectomy; Receptors, Estrogen / antagonists & inhibitors; Receptors, Estrogen / deficiency; Receptors, Estrogen / genetics; Receptors, Progesterone / analysis
TL;DR:
Results show that coumestrol has anti-estrogenic actions in the brain and pituitary and that ERα mediates these effects.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2001 journal article
Soy Isoflavone Supplements Antagonize Reproductive Behavior and Estrogen Receptor α- and β-Dependent Gene Expression in the Brain*
Endocrinology, 142(7), 2946–2952.
MeSH headings : Animals; Brain / physiology; Chromatography, High Pressure Liquid; Estradiol / metabolism; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression / drug effects; Isoflavones / analysis; Isoflavones / pharmacology; Male; RNA, Messenger / metabolism; Rats; Rats, Long-Evans; Receptors, Estrogen / genetics; Receptors, Estrogen / physiology; Receptors, Oxytocin / metabolism; Sexual Behavior, Animal / drug effects; Soybeans / chemistry; Uterus / drug effects
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2001 journal article
Posttranscriptional silencing of cytochrome P4501A1 (CYP1A1) during zebrafish (Danio rerio) development
Developmental Dynamics, 222(4), 645–654.
author keywords: cytochrome P450; monooxygenase; zebrafish; Ah receptor; dioxin
MeSH headings : Aging / metabolism; Animals; Base Sequence / genetics; Cloning, Molecular; Cytochrome P-450 CYP1A1 / genetics; Cytochrome P-450 CYP1A1 / metabolism; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / physiology; Environmental Pollutants / poisoning; Gene Expression Regulation; Gene Expression Regulation, Developmental; Gene Silencing; Molecular Sequence Data; Polychlorinated Dibenzodioxins / poisoning; RNA, Messenger / metabolism; Transcription, Genetic; Zebrafish / embryology; Zebrafish / genetics; Zebrafish / metabolism
TL;DR:
The data suggest that TCDD‐mediated induction of CYP1A1 activity is regulated differentially in developing and mature systems.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2001 journal article
Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio).
Environmental Health Perspectives, 109(8), 845–849.
MeSH headings : Animals; Biomarkers / analysis; Cytochrome P-450 CYP1A1 / genetics; Eye Abnormalities / chemically induced; Green Fluorescent Proteins; Luminescent Proteins / biosynthesis; Models, Animal; Morphogenesis / drug effects; Polychlorinated Dibenzodioxins / toxicity; Receptors, Aryl Hydrocarbon / genetics; Spine / abnormalities; Transcription, Genetic; Transfection; Zebrafish / embryology
TL;DR:
An inducible in vivo reporter system to examine expression of the aryl hydrocarbon receptor (AhR) during development in zebrafish (Danio rerio) and whether AhR-regulated GFP expression correlated with sites of TCDD toxicity is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2001 journal article
Corrigendum to: “The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13” [Gene 261 (2000) 235–242]
Gene, 269(1-2), 227.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: February 13, 2019
2001 journal article
Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA
Nucleic Acids Research, 29(2), 439–448.
MeSH headings : Adenosine Triphosphate / chemistry; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; DNA (Cytosine-5-)-Methyltransferases / chemistry; DNA (Cytosine-5-)-Methyltransferases / genetics; Guanosine Triphosphate / chemistry; Humans; Mice; Models, Molecular; Molecular Sequence Data; Multigene Family; Nucleic Acid Denaturation; Protein Denaturation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins / chemistry; Sequence Deletion; Sequence Homology, Amino Acid
TL;DR:
It is shown that homologs of DNMT2, which are present in some organisms that are not known to methylate their genomes, contain a specific target-recognizing sequence motif including an invariant CysPheThr tripeptide.
(via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2001 review
Novel immune-type receptor genes
[Review of ]. IMMUNOLOGICAL REVIEWS, 181(1), 250–259.
MeSH headings : Animals; Biological Evolution; Fishes / genetics; Fishes / immunology; Genetic Variation; Genome; Models, Biological; Molecular Structure; Polymerase Chain Reaction; Receptors, Immunologic / chemistry; Receptors, Immunologic / genetics
TL;DR:
The presence in NITR of V regions that are related closely to those found in Ig and TCR, as well as regulatory motifs and other structural features that are characteristic of immune inhibitory receptors encoded at the leukocyte receptor cluster, suggests that the NITRs are representative of an integral stage in the evolution of innate and adaptive immune function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 journal article
Immune-type receptor genes in zebrafish share genetic and functional properties with genes encoded by the mammalian leukocyte receptor cluster
Proceedings of the National Academy of Sciences, 98(12), 6771–6776.
MeSH headings : Amino Acid Sequence; Animals; Biological Evolution; Conserved Sequence; Genes, Immunoglobulin; Genetic Linkage; Killer Cells, Natural / immunology; Molecular Sequence Data; Multigene Family; Receptors, Immunologic / genetics; Zebrafish / genetics; Zebrafish / immunology
TL;DR:
Antibody-induced crosslinking of Nitrs that have been introduced into a human natural killer cell line inhibits the phosphorylation of mitogen-activated protein kinase that is triggered by natural killer-sensitive tumor target cells.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2001 journal article
Extraordinary variation in a diversified family of immune-type receptor genes
Proceedings of the National Academy of Sciences, 98(24), 13832–13837.
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Evolution, Molecular; Gene Expression; Genetic Variation; Ictaluridae; Immunoglobulin Variable Region / classification; Immunoglobulin Variable Region / genetics; Lymphocyte Culture Test, Mixed; Molecular Sequence Data; Receptors, Immunologic / classification; Receptors, Immunologic / genetics
TL;DR:
Eleven related genes encoding distinct structural forms have been identified in Ictalurus punctatus (channel catfish), a well characterized immunological model system that represents a third independent bony fish lineage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2001 journal article
Cloning and sequence analysis of a zebrafish cDNA encoding DNA (cytosine-5)-methyltransferase-1
GENESIS, 30(4), 213–219.
author keywords: DNA cytosine-5-methyltransferase; DNA mtase; Dnmt1; zebrafish; methylation; development
MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases / chemistry; DNA (Cytosine-5-)-Methyltransferases / genetics; DNA, Complementary / genetics; Molecular Sequence Data; Open Reading Frames / genetics; Polymerase Chain Reaction; Sequence Homology; Zebrafish / genetics; Zebrafish Proteins / chemistry; Zebrafish Proteins / genetics
TL;DR:
The determination of the full‐length cDNA sequence corresponding to the zebrafish DNA (cytosine‐5‐) methyltransferase gene, Dnmt1, is 4,907 bases long and has an open reading frame predicted to encode a 1,499 amino acid protein that is similar in size and sequence to a number of other methyltransferases identified in other organisms.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 chapter
Pesticide disposition: dermal absorption
In Handbook of Pesticide Toxicology (2nd ed.) (pp. 515–530).
Source: NC State University Libraries
Added: August 6, 2018
2001 chapter
Interleukin-13 induced mucous cell hyperplasia in airway epithelium.
In Cilia and mucus: from development to respiratory disease. (pp. 253–263).
Source: NC State University Libraries
Added: August 6, 2018
2001 article
Autocrine production of TGFa mediates interleukin 13-induced proliferation of human airway epithelial cells during development of a mucous phenotype in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A738.
Source: NC State University Libraries
Added: August 6, 2018
2001 journal article
Neonatal low- and high-dose exposure to estradiol benzoate in the male rat: II. Effects on male puberty and the reproductive tract
BIOLOGY OF REPRODUCTION, 65(5), 1506–1517.
author keywords: early development; environment; estradiol; prostate; puberty; steroid hormones; toxicology
MeSH headings : Aging; Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System / metabolism; Dose-Response Relationship, Drug; Epididymis / drug effects; Epididymis / growth & development; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Estradiol / pharmacology; Genitalia, Male / drug effects; Genitalia, Male / growth & development; Liver / drug effects; Liver / enzymology; Male; Organ Size / drug effects; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sexual Maturation / drug effects; Steroid Hydroxylases / metabolism; Testis / drug effects; Testis / growth & development; Testosterone / blood
TL;DR:
Results showed an inverted U-shaped dose-response profile for testis and epididymis weights in 35-day-old SD rats, with increased organ sizes at the low-dose end of the treatment, which suggests an advancement of puberty as the cause for increased reproductive organ weights.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2001 journal article
Factors controlling alkylbenzene sorption to municipal solid waste
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 35(22), 4569–4576.
Contributors: B. Wu n, C. Taylor n, D. Knappe n, M. Nanny n & M. Barlaz n
MeSH headings : Adsorption; Biological Availability; Fatty Acids / chemistry; Hazardous Waste; Plastics; Refuse Disposal; Solubility; Solvents / chemistry; Toluene / chemistry; Volatilization; Xylenes / chemistry
TL;DR:
Results of this study showed that sorbent organic matter affinity for hydrophobic organic contaminants (HOCs) increases with increasing extent of MSW decomposition because of the recalcitrance of plastics and the preferential degradation of polar biopolymers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 journal article
The fungicide propiconazole interferes with embryonic development of the crustacean Daphnia magna
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 20(3), 502–509.
author keywords: development; embryos; crustaceans; daphnids; propiconazole
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2001 journal article
Temporal and quantitative changes in sexual reproductive cycling of the cladoceran Daphnia magna by a juvenile hormone analog
JOURNAL OF EXPERIMENTAL ZOOLOGY, 290(2), 148–155.
MeSH headings : Animals; Daphnia / physiology; Female; Juvenile Hormones / physiology; Male; Methoprene / pharmacology; Parthenogenesis; Reproduction
TL;DR:
It is demonstrated that methoprene uncouples the coordinate production of males and resting eggs during the sexual reproductive period of D. magna.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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