Works Published in 2000

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Displaying works 301 - 320 of 349 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2000 journal article

Identification of a collectin-like protein in pig serum that binds a component in perienteric fluid from Ascaris suum

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 23(2), 113–124.

By: B. Watson n & B. Hammerberg n

author keywords: collectin; Ascaris suum; pig; serum; polysaccharide
MeSH headings : Animals; Antibodies, Monoclonal; Ascaris suum / immunology; Carrier Proteins / blood; Carrier Proteins / immunology; Collectins; Electrophoresis, Polyacrylamide Gel / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Mice; Mice, Inbred BALB C; Swine; Swine Diseases / blood; Swine Diseases / immunology
TL;DR: This is the first report of a porcine CLP and the binding of a CLP to components of the common nematode Ascaris suum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Efficient synthesis of monoacyl dipyrromethanes and their use in the preparation of sterically unhindered trans-porphyrins

JOURNAL OF ORGANIC CHEMISTRY, 65(4), 1084–1092.

By: P. Rao n, B. Littler n, G. Geier n & J. Lindsey n

MeSH headings : Acylation; Magnetic Resonance Spectroscopy; Methane / analogs & derivatives; Methane / chemical synthesis; Methane / chemistry; Methane / metabolism; Molecular Structure; Porphyrins / chemical synthesis; Porphyrins / chemistry; Porphyrins / metabolism; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / metabolism; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro - Signaling pathways controlling surface and gene expression

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(6), 685–692.

By: T. Krunkosky n, B. Fischer n, L. Martin n, N. Jones n, N. Akley n & K. Adler n

MeSH headings : Antibodies, Monoclonal; Bronchi / cytology; Cell Line; Epithelial Cells / enzymology; Epithelial Cells / immunology; Flow Cytometry; Gene Expression / immunology; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1 / genetics; Intercellular Adhesion Molecule-1 / immunology; L-Lactate Dehydrogenase / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Promoter Regions, Genetic / physiology; RNA Processing, Post-Transcriptional / physiology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Respiratory Mucosa / cytology; Signal Transduction / immunology; Tumor Necrosis Factor-alpha / pharmacology
TL;DR: The intracellular signaling pathway leading to enhanced expression appeared to involve activation of a phospholipase C that hydrolyzes phosphatidylcholine (PC-PLC) becaus... (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway

MOLECULAR AND CELLULAR BIOLOGY, 20(2), 672–683.

By: R. Lee*, C. Albanese*, M. Fu*, . M D'Amico, B. Lin n, G. Watanabe*, G. Haines*, P. Siegel* ...

MeSH headings : Animals; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Transformation, Neoplastic / pathology; Cyclin D1 / antagonists & inhibitors; Cyclin D1 / genetics; Cyclin D1 / metabolism; DNA-Binding Proteins / metabolism; E2F Transcription Factors; E2F1 Transcription Factor; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mammary Glands, Animal / metabolism; Mammary Glands, Animal / pathology; Mice; Mice, Nude; Mice, Transgenic; Mitogen-Activated Protein Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinases / metabolism; Monomeric GTP-Binding Proteins / genetics; Monomeric GTP-Binding Proteins / metabolism; Mutation / genetics; Promoter Regions, Genetic / genetics; Proto-Oncogene Mas; RNA, Antisense / genetics; RNA, Antisense / physiology; Receptor, ErbB-2 / antagonists & inhibitors; Receptor, ErbB-2 / genetics; Receptor, ErbB-2 / metabolism; Retinoblastoma-Binding Protein 1; Sp1 Transcription Factor / metabolism; Sp3 Transcription Factor; Transcription Factor DP1; Transcription Factors / metabolism; Transcriptional Activation; Tumor Cells, Cultured
TL;DR: It is demonstrated that E2F-1 mediates a Neu-signaling cascade tocyclin D1 and identify cyclin D 1 as a critical downstream target of neu-induced transformation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Correcting for measurement error in individual-level covariates in nonlinear mixed effects models

BIOMETRICS, 56(2), 368–375.

By: H. Ko & M. Davidian n

author keywords: laplace's approximation; random effects; regression calibration; small sigma
MeSH headings : Biometry / methods; Calibration; Models, Statistical; Pharmacokinetics; Regression Analysis; Virus Physiological Phenomena
TL;DR: Methods to take account of measurement error that correct this bias are developed and may be implemented with standard software and demonstrated their utility via simulation and application to data from a study of HIV dynamics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Aluminum accumulation at nuclei of cells in the root tip. Fluorescence detection using lumogallion and confocal laser scanning microscopy

PLANT PHYSIOLOGY, 123(2), 543–552.

By: I. Silva, T. Smyth*, D. Moxley*, T. Carter n, N. Allen* & T. Rufty n

MeSH headings : Aluminum / metabolism; Benzenesulfonates / chemistry; Cell Nucleus / metabolism; Genotype; Lasers; Microscopy, Confocal / methods; Plant Roots / metabolism; Soybeans / genetics; Soybeans / metabolism; Spectrometry, Fluorescence / methods
TL;DR: The results support an important role for exclusion in Al tolerance and indicate that the Al-tolerant genotype accumulated lower amounts of Al in meristematic and differentiating cells of the root tip and their cell walls. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

A survey of acid catalysts for use in two-step, one-flask syntheses of meso-substituted porphyrinic macrocycles

ORGANIC LETTERS, 2(12), 1745–1748.

By: G. Geier n, Y. Ciringh n, F. Li n, D. Haynes n & J. Lindsey n

MeSH headings : Acids, Noncarboxylic / chemistry; Aldehydes / chemistry; Catalysis; Porphyrins / chemical synthesis; Pyrroles / chemistry
TL;DR: The scope of acid catalysis was found to be very broad, with 35 of 45 acids providing TPP in yields ranging from 5% to 58%. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 46(1), 179–185.

By: Z. Vujaskovic*, J. Poulson*, A. Gaskin*, D. Thrall n, R. Page n, H. Charles*, . MacFall*, D. Brizel* ...

author keywords: tumors; hyperthermia blood how; pO(2); pH; thermal dose
MeSH headings : Animals; Combined Modality Therapy; Dogs; Female; Hydrogen-Ion Concentration; Hyperthermia, Induced / methods; Male; Oxygen / metabolism; Partial Pressure; Sarcoma, Experimental / blood supply; Sarcoma, Experimental / metabolism; Sarcoma, Experimental / radiotherapy; Sarcoma, Experimental / therapy; Soft Tissue Neoplasms / blood supply; Soft Tissue Neoplasms / metabolism; Soft Tissue Neoplasms / radiotherapy; Soft Tissue Neoplasms / therapy
TL;DR: This study suggests that hyperthermia has biphasic effects on tumor physiologic parameters, and suggests that the thermal threshold for vascular damage is higher in spontaneous tumors than in more rapidly growing rodent tumors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Rational synthesis of meso-substituted porphyrins bearing one nitrogen heterocyclic group

JOURNAL OF ORGANIC CHEMISTRY, 65(7), 2249–2252.

MeSH headings : Heterocyclic Compounds / chemical synthesis; Indicators and Reagents; Porphyrins / chemical synthesis
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Seroprevalence of Ehrlichia canis, Ehrlichia equi, and Ehrlichia risticii in sick dogs from North Carolina and Virginia

Journal of Veterinary Internal Medicine, 14(1), 50–55.

TL;DR: Ehrlichia canis, E. equi, and E. risticii seroprevalence was determined by microimmunofluorescent antibody testing in a sequential population of 1,845 sick dogs admitted during a 1-year period to the North Carolina State University Veterinary Teaching Hospital to indicate that ehrlichiosis was not diagnosed in the majority of serologically confirmed cases. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2000 journal article

Prevalence of Bartonella henselae Antibody in Florida Panthers

Journal of Wildlife Diseases, 36(1), 157–160.

By: D. Rotstein*, S. Taylor*, J. Bradley n & E. Breitschwerdt n

author keywords: Bartonellosis; Bartonella henselae; Florida panther; mountain lion; Puma concolor coryi; Puma concolor stanleyana; serology
MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Bartonella henselae / immunology; Carnivora; Female; Florida / epidemiology; Male; Seroepidemiologic Studies; Texas
TL;DR: Serum samples from 28 free-ranging Florida panthers and seven mountain lions living in south Florida between 1997 to 1998 were tested for antibodies to Bartonella henselae and the seroprevalence in animals <2-yr from southern Florida was similar to prevalences reported in mountain lions or domestic felids in California. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2000 journal article

Host and bacterial factors involved in the innate ability of mouse macrophages to eliminate internalized unopsonized Escherichia coli

INFECTION AND IMMUNITY, 68(1), 125–132.

MeSH headings : Adhesins, Bacterial / immunology; Adhesins, Escherichia coli; Animals; Cell Line; Cytotoxicity, Immunologic; Escherichia coli / immunology; Fimbriae Proteins; Macrophages, Peritoneal / immunology; Macrophages, Peritoneal / microbiology; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Phagocytosis; Species Specificity
TL;DR: Host and bacterial factors involved in the nonopsonic phagocytosis and killing of Escherichia coli K-12 by mouse macrophages were examined to better understand genetic and cellular factors that influence innate immunity and there was no correlation between the bacteriocidal effectiveness of amacrophage population and the number of bacteria bound per macrophage. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Histologic and immunohistochemical characterization of lens capsular plaques in dogs with cataracts

AMERICAN JOURNAL OF VETERINARY RESEARCH, 61(2), 139–143.

By: C. Colitz n, D. Malarkey*, M. Dykstra*, M. McGahan & M. Davidson*

MeSH headings : Actins / analysis; Animals; Cataract / pathology; Cataract / veterinary; Cataract Extraction / veterinary; Dog Diseases / pathology; Dogs; Fibronectins / analysis; Histocytochemistry; Humans; Immunohistochemistry / methods; Lens, Crystalline / pathology; Lens, Crystalline / ultrastructure; Tenascin / analysis; Transforming Growth Factor beta / analysis
TL;DR: Canine lens capsular plaques are histologically and immunohistochemically similar to posterior capsule opacification and subcapsular cataracts in humans, which suggests that the canine condition, like the human conditions, is associated with fibrous metaplasia of lens epithelial cells. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 article

Granulomatous disease associated with Bartonella infection in 2 dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 37–42.

By: B. Pappalardo n, T. Brown*, J. Gookin n, C. Morrill n & E. Breitschwerdt n

author keywords: canine; infectious; lymphadenopathy; pathology
TL;DR: This is the 1st report of granulomatous disease in dogs associated with Bartonella infection, and an 11-year-old mixed-breed dog was referred for evaluation of a 6-week history of serous nasal discharge. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 article

Food hypersensitivity reactions in Soft Coated Wheaten Terriers with protein-losing enteropathy or protein-losing nephropathy or both: Gastroscopic food sensitivity testing, dietary provocation, and fecal immunoglobulin E

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 60–67.

By: S. Vaden n, B. Hammerberg n, D. Davenport, S. Orton n, M. Trogdon n, L. Melgarejo*, S. VanCamp n, D. Williams*

author keywords: food allergy; glomerulonephritis; inflammatory bowel disease
Source: Web Of Science
Added: August 6, 2018

2000 book

Fish disease: Diagnosis and treatment

Ames: Iowa State University.

By: E. Noga

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Familial protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers: 222 cases (1983-1997)

JOURNAL OF VETERINARY INTERNAL MEDICINE, 14(1), 68–80.

By: M. Littman, D. Dambach, S. Vaden* & U. Giger

author keywords: glomerulonephritis; inflammatory bowel disease; lymphangiectasia; lymphangitis
TL;DR: A new, distinctive familial predisposition for both PLE and PLN has been recognized in the SCWT breed, and the prognosis is poor. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Characterization of Lyme disease spirochetes isolated from ticks and vertebrates in North Carolina

JOURNAL OF WILDLIFE DISEASES, 36(1), 48–55.

By: . Ryan n, C. Apperson n, P. Orndorff n & J. Levine n

author keywords: Borrelia burgdorferi; isolate characterization; Lyme disease; ticks; vertebrates
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Arachnid Vectors / microbiology; Bacterial Outer Membrane Proteins / analysis; Bacterial Outer Membrane Proteins / immunology; Blotting, Western / veterinary; Borrelia burgdorferi Group / classification; Borrelia burgdorferi Group / genetics; Borrelia burgdorferi Group / immunology; Chickens / microbiology; DNA, Bacterial / analysis; Disease Reservoirs; Dogs; Electrophoresis, Polyacrylamide Gel / veterinary; Lizards / microbiology; North Carolina; Plasmids / chemistry; Rabbits / microbiology; Raccoons / microbiology; Rodentia / microbiology; Species Specificity; Ticks / microbiology; Vertebrates / microbiology
TL;DR: This study demonstrates that B. burgdorferi sensu stricto is present and naturally transmitted on the Outer Banks and in the Coastal Plain and Piedmont regions of North Carolina. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

A spontaneously arising porcine model of bullous pemphigoid

ARCHIVES OF DERMATOLOGICAL RESEARCH, 292(1), 37–45.

By: T. Olivry*, M. Mirsky, W. Singleton, S. Dunston*, A. Borrillo*, L. Xu*, T. Traczyk*, D. Rosolia, L. Chan*

Contributors: T. Olivry*, M. Mirsky, W. Singleton, S. Dunston*, A. Borrillo*, L. Xu*, T. Traczyk*, D. Rosolia, L. Chan*

author keywords: basement membrane zone; bullous pemphigoid; pig
MeSH headings : Amino Acid Sequence; Animals; Autoantigens / analysis; Carrier Proteins; Collagen; Cytoskeletal Proteins; Disease Models, Animal; Dystonin; Enzyme-Linked Immunosorbent Assay; Epitopes / analysis; Fluorescent Antibody Technique; Immunoblotting; Immunosorbent Techniques; Microscopy, Electron; Microscopy, Fluorescence; Microscopy, Immunoelectron; Molecular Sequence Data; Nerve Tissue Proteins; Non-Fibrillar Collagens; Pemphigoid, Bullous / immunology; Pemphigoid, Bullous / metabolism; Pemphigoid, Bullous / pathology; Skin / chemistry; Skin / pathology; Skin / ultrastructure; Swine; Swine, Miniature
TL;DR: This novel porcine acquired blistering dermatosis could be proposed as a valuable model to conduct immunomechanistic studies on the natural progression of BP, correlation of autoreactive T cells or autoantibodies with disease activity, and the role of eosinophils in the blistering process, as these diseases cannot be modeled easily in human patients or in murine passive transfer models. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2000 journal article

Equine bullous pemphigoid IgG autoantibodies target linear epitopes in the NC16A ectodomain of collagen XVII (BP180, BPAG2)

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 73(1), 45–52.

By: T. Olivry*, A. Borrillo, L. Xu, S. Dunston*, N. Slovis, V. Affolter, T. DeManuelle, L. Chan

Contributors: T. Olivry*, A. Borrillo, L. Xu, S. Dunston*, N. Slovis, V. Affolter, T. Demanuelle, L. Chan

author keywords: autoimmunity; basement membrane zone; bullous pemphigoid; horse
MeSH headings : Animals; Autoantibodies / analysis; Autoantibodies / immunology; Autoantigens / immunology; Carrier Proteins; Collagen; Cytoskeletal Proteins; Dystonin; Enzyme-Linked Immunosorbent Assay; Epitopes; Horse Diseases / immunology; Horses; Immunoblotting; Immunoglobulin G / analysis; Immunoglobulin G / immunology; Microscopy, Fluorescence; Nerve Tissue Proteins; Non-Fibrillar Collagens; Pemphigoid, Bullous / immunology; Pemphigoid, Bullous / veterinary
TL;DR: Equine BP could be proposed, therefore, as another spontaneous model of this most common basement membrane autoimmune dermatosis of humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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