Works Published in 2013

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Displaying works 41 - 60 of 61 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2013 journal article

2,4-Di-tert-butylphenol from sweet potato protects against oxidative stress in PC12 cells and in mice

Journal of Medicinal Food, 16(11), 977–983.

By: S. Choi, J. Kim, H. Kim, K. Harris, C. Kim, G. Park, C. Park, D. Shin

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Serum Metabolic Signatures Induced By a Three-Day Intensified Exercise Period Persist After 14 h of Recovery in Runners

JOURNAL OF PROTEOME RESEARCH, 12(10), 4577–4584.

By: D. Nieman*, R. Shanely*, N. Gillitt*, K. Pappan* & M. Lila n

author keywords: metabolomics; running; lipids; amino acids; carnitines
MeSH headings : Adult; Amino Acids / blood; Female; Gas Chromatography-Mass Spectrometry; Humans; Lipid Metabolism; Lipids / blood; Male; Metabolome; Middle Aged; Physical Exertion; Running / physiology; Young Adult
TL;DR: Runners experienced a profound systemic shift in blood metabolites related to energy production especially from the lipid super pathway following 3 days of heavy exertion that was not fully restored to pre-exercise levels after 14 h recovery. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Concord Grape Pomace Polyphenols Cornplexed to Soy Protein Isolate Are Stable and Hypoglycemic in Diabetic Mice

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61(47), 11428–11433.

author keywords: grape pomace; polyphenols; soy protein isolate; nutrition; hyperglycemia
MeSH headings : Animals; Blood Glucose; Chemical Fractionation / methods; Diabetes Mellitus, Experimental / drug therapy; Drug Stability; Hyperglycemia / drug therapy; Hyperglycemia / metabolism; Hypoglycemic Agents / pharmacology; Male; Mice; Mice, Inbred C57BL; Polyphenols / chemistry; Polyphenols / isolation & purification; Polyphenols / pharmacology; Proanthocyanidins / analysis; Soybean Proteins / chemistry; Soybean Proteins / pharmacology; Vitis / chemistry
TL;DR: GP-SPI allows the capture of grape pomace polyphenols in a protein-rich food matrix and may be useful as a functional food ingredient for the management of blood glucose levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Effects of Brussels sprouts and their phytochemical components on oxidative stress-induced neuronal damages in PC12 cells and ICR mice

Journal of Medicinal Food, 16(11), 1057–1061.

By: J. Kim, E. Shin, C. Kim, G. Park, S. Choi, C. Park, D. Shin

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Composition of fatty acids in commercially available tree nuts and their relationship with protective effects against oxidative stress-induced neurotoxicity

Food Science and Biotechnology, 22(4), 1097–1104.

By: J. Kim, E. Shin, C. Kim, G. Park, S. Choi, H. Cho, D. Shin

Source: NC State University Libraries
Added: August 6, 2018

2013 article

'Von' Thornless Blackberry

Fernandez, G. E., Ballington, J. R., & Perkins-Veazie, P. (2013, May). HORTSCIENCE, Vol. 48, pp. 654–656.

author keywords: Rubus; fruit breeding
TL;DR: ‘Von’ is a new floricane-fruiting blackberry released by North Carolina State University that is a productive plant with high yield, late harvest season, excellent postharvest attributes, and small seed size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2013 conference paper

Yield and postharvest attributes of caneberries grown under high tunnels and in the open field in North Carolina

International symposium on high tunnel horticultural crop production, 987, 89–98.

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Food-compatible method for the efficient extraction and stabilization of cranberry pomace polyphenols

FOOD CHEMISTRY, 141(4), 3664–3669.

author keywords: Cranberry pomace; Polyphenols; Proanthocyanidins; Anthocyanins; Soy protein isolate
MeSH headings : Chemical Fractionation / methods; Fruit / chemistry; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Polyphenols / chemistry; Polyphenols / isolation & purification; Vaccinium macrocarpon / chemistry; Waste Products / analysis
TL;DR: The extraction and stabilization of cranberry pomace polyphenols using SPI provides an innovative approach for utilizing pomACE in the development of novel food ingredients. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Stable Binding of Alternative Protein-Enriched Food Matrices with Concentrated Cranberry Bioflavonoids for Functional Food Applications

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61(28), 6856–6864.

By: M. Grace n, I. Guzman n, D. Roopchand*, K. Moskal*, D. Cheng*, N. Pogrebnyak*, I. Raskin*, A. Howell*, M. Lila n

Contributors: M. Grace n, I. Guzman n, D. Roopchand*, K. Moskal*, D. Cheng*, N. Pogrebnyak*, I. Raskin*, A. Howell*, M. Lila n

author keywords: A-type proanthocyanidins; polyphenols; Vaccinium macrocarpon; antiadhesion; antimicrobial; shelf stability
MeSH headings : Anthocyanins / analysis; Anti-Bacterial Agents / administration & dosage; Arachis / chemistry; Beverages / analysis; Cannabis / chemistry; Dietary Proteins / metabolism; Flavonoids / metabolism; Food, Fortified; Fruit / chemistry; Functional Food; Plant Proteins / metabolism; Polyphenols / metabolism; Proanthocyanidins / analysis; Soybean Proteins / metabolism; Urinary Tract Infections / prevention & control; Vaccinium macrocarpon / chemistry
TL;DR: Nutritional and sensory analyses indicated that the targeted CB-matrix combinations have high potential for incorporation in functional food formulations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Berry and citrus phenolic compounds inhibit dipeptidyl peptidase IV: Implications in diabetes management

Evidence-Based Complementary and Alternative Medicine.

By: J. Fan, M. Johnson, M. Lila, G. Yousef & E. Mejia

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Acceleration of cutaneous wound healing by brassinosteroids

WOUND REPAIR AND REGENERATION, 21(5), 688–696.

Contributors: D. Esposito*, T. Rathinasabapathy*, B. Schmidt*, M. Shakarjian*, S. Komarnytsky n & I. Raskin*

MeSH headings : Administration, Topical; Animals; Blotting, Western; Brassinosteroids / pharmacology; Cell Proliferation; Cells, Cultured; Intercellular Adhesion Molecule-1 / drug effects; Intercellular Adhesion Molecule-1 / metabolism; Male; Mice; Mice, Inbred C57BL; Signal Transduction / drug effects; Skin / injuries; Skin / pathology; Transforming Growth Factor beta / drug effects; Transforming Growth Factor beta / metabolism; Tumor Necrosis Factor-alpha / drug effects; Tumor Necrosis Factor-alpha / metabolism; Wound Healing / drug effects
TL;DR: Topical application of brassinosteroids accelerates wound healing by positively modulating inflammatory and reepithelialization phases of the wound repair process, in part by enhancing Akt signaling in the skin at the edges of the wounds and enhancing migration of fibroblasts in the wounded area. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Steroidal glycosides from the bulbs of Easter lily (Lilium longiflorum Thunb.) promote dermal fibroblast migration in vitro

JOURNAL OF ETHNOPHARMACOLOGY, 148(2), 433–440.

By: D. Esposito n, J. Munafo*, T. Lucibello*, M. Baldeon*, S. Komarnytsky n & T. Gianfagna*

author keywords: Lilium longiflorum Thunb.; Steroidal glycoside; Furostanol saponin; Transforming growth factor beta; Nitric oxide; Wound healing
MeSH headings : 3T3 Cells; Animals; Carbohydrate Sequence; Cell Movement / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Dermis / cytology; Dermis / drug effects; Dermis / metabolism; Ethnopharmacology / methods; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Glycosides / chemistry; Glycosides / pharmacology; Human Umbilical Vein Endothelial Cells; Humans; Lilium / chemistry; Mice; Molecular Sequence Data; Nitric Oxide / metabolism; Plant Extracts / chemistry; Plant Extracts / pharmacology; Plant Roots / chemistry; Skin / cytology; Skin / drug effects; Skin / metabolism; Steroids / chemistry; Steroids / pharmacology; Transforming Growth Factor beta / metabolism; Wound Healing / drug effects
TL;DR: This is the first evidence that steroidal glycosides from Lilium longiflorum may potentially play a role in the wound healing process and may provide a scientific basis for the historical use of lily bulbs for this purpose. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Influence of a polyphenol-enriched protein powder on exercise-induced inflammation and oxidative stress in athletes: A randomized trial using a metabolomics approach

PLoS One, 8(8).

By: D. Nieman, N. Gillitt, A. Knab, R. Shanely, K. Pappan, F. Jin, M. Lila

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Bioactive polyphenols from muscadine grape and blackcurrant stably concentrated onto protein-rich matrices for topical applications

INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, 35(4), 394–401.

author keywords: antimicrobial; blackcurrant; muscadine grape; polyphenols; topical applications; tyrosinase
MeSH headings : Polyphenols / administration & dosage; Polyphenols / pharmacology; Proteins / drug effects; Ribes / chemistry; Vitis / chemistry
TL;DR: Natural botanical agents that are antimicrobial, or that modulate skin hyperpigmentation via tyrosinase inhibition, are increasingly sought in the cosmetic industry. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Anthocyanins and proanthocyanidins from blueberry-blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate-utilizing enzymes in vitro

MOLECULAR NUTRITION & FOOD RESEARCH, 57(7), 1182–1197.

By: M. Johnson*, E. Mejia*, J. Fan*, M. Lila n & G. Yousef n

author keywords: Anthocyanin; Berry; Diabetes; Hydrolysable tannins; Inflammation; Proanthocyanidin
MeSH headings : Animals; Anthocyanins / analysis; Anthocyanins / pharmacology; Antioxidants / pharmacology; Beverages; Blueberry Plants / chemistry; Cell Line, Tumor; Cell Proliferation / drug effects; Fermentation; Fruit / chemistry; Glucosides / analysis; Inflammation / prevention & control; Lipopolysaccharides / adverse effects; Macrophages / drug effects; Macrophages / metabolism; Mice; NF-kappa B / genetics; NF-kappa B / metabolism; Plant Extracts / pharmacology; Polyphenols / pharmacology; Proanthocyanidins / pharmacology; Wine / analysis; alpha-Amylases / metabolism; alpha-Glucosidases / metabolism
TL;DR: ANCs demonstrated that delphinidin-3-arabinoside effectively inactivated dipeptidyl peptidase-IV by binding with the lowest interaction energy (-3228 kcal/mol). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells

JOURNAL OF CELLULAR PHYSIOLOGY, 228(5), 1120–1126.

By: S. Komarnytsky n, D. Esposito n, A. Poulev* & I. Raskin*

MeSH headings : 3-Hydroxysteroid Dehydrogenases / antagonists & inhibitors; 3-Hydroxysteroid Dehydrogenases / biosynthesis; Adrenal Cortex Hormones / metabolism; Androstenedione / analogs & derivatives; Animals; Cell Line, Tumor; Cholesterol Side-Chain Cleavage Enzyme / antagonists & inhibitors; Cholesterol Side-Chain Cleavage Enzyme / biosynthesis; Corticosterone / biosynthesis; Corticosterone / metabolism; Cortisone / metabolism; Glycosides / administration & dosage; Humans; Pregnanes / administration & dosage; Progesterone / analogs & derivatives; Progesterone / biosynthesis; Steroid 11-beta-Hydroxylase / antagonists & inhibitors; Steroid 11-beta-Hydroxylase / biosynthesis; Steroid 17-alpha-Hydroxylase / antagonists & inhibitors; Steroid 17-alpha-Hydroxylase / biosynthesis; Structure-Activity Relationship
TL;DR: Data suggest that pregnane glycosides specifically suppress steroidogenesis through strong inhibition of 11β‐hydroxylase and steroid 17‐alpha‐monooxygenase, and weak inhibition of cytochrome P450 side chain cleavage enzyme and 21β‐ dehydrogenase/isomerase, but not 3 β‐hydroxysteroid dehydrogenases/isomersase. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Efficient Quantification of the Health-Relevant Anthocyanin and Phenolic Acid Profiles in Commercial Cultivars and Breeding Selections of Blueberries (Vaccinium spp.)

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61(20), 4806–4815.

By: G. Yousef n, A. Brown n, Y. Funakoshi n, F. Mbeunkui n, M. Grace n, J. Ballington n, A. Loraine*, M. Lila n

Contributors: G. Yousef n, A. Brown n, Y. Funakoshi n, F. Mbeunkui n, M. Grace n, J. Ballington n, A. Loraine*, M. Lila n

author keywords: anthocyanins; chlorogenic acid; blueberry; HPLC-DAD-MS; Vaccinium spp.; freeze-drying; health benefits
MeSH headings : Anthocyanins / analysis; Blueberry Plants / chemistry; Breeding; Chromatography, High Pressure Liquid / methods; Food, Preserved / analysis; Frozen Foods / analysis; Fruit / chemistry; Genotype; Glucosides / analysis; Health Promotion; Humans; Hydroxybenzoates / analysis; Plant Extracts / chemistry; Species Specificity; Tandem Mass Spectrometry / methods
TL;DR: An improved protocol was developed for the accurate, efficient, and rapid comparative screening for large blueberry sample sets and different genotypes frequently had comparable overall levels of total anthocyanins and phenolic acids, but differed dramatically in individual profiles of compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Blueberry polyphenol-enriched soybean flour reduces hyperglycemia, body weight gain and serum cholesterol in mice

PHARMACOLOGICAL RESEARCH, 68(1), 59–67.

author keywords: Metabolic syndrome; Diabetes; Blueberry; Soybean; Anthocyanins; Polyphenols
MeSH headings : Animals; Anthocyanins / pharmacology; Anthocyanins / therapeutic use; Blueberry Plants; Cell Line; Cell Line, Tumor; Cholesterol / blood; Flour; Glucose / metabolism; Hyperglycemia / drug therapy; Hyperglycemia / metabolism; Hypoglycemic Agents / pharmacology; Hypoglycemic Agents / therapeutic use; Male; Mice; Mice, Inbred C57BL; Myoblasts / metabolism; Polyphenols / pharmacology; Polyphenols / therapeutic use; Rats; Soybeans; Weight Gain / drug effects
TL;DR: The results indicate that delivery of blueberry polyphenols stabilized in a high-protein food matrix may be useful for the dietary management of pre-diabetes and/or diabetes. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Effects of Pregnane Glycosides on Food Intake Depend on Stimulation of the Melanocortin Pathway and BDNF in an Animal Model

Journal of Agricultural and Food Chemistry, 61(8), 1841–1849.

By: S. Komarnytsky n, D. Esposito n, T. Rathinasabapathy*, A. Poulev* & I. Raskin*

Contributors: S. Komarnytsky n, D. Esposito n, T. Rathinasabapathy*, A. Poulev* & I. Raskin*

author keywords: appetite; satiety; body weight; milkweed; Asclepias
MeSH headings : Animals; Appetite / drug effects; Asclepias / chemistry; Brain-Derived Neurotrophic Factor / genetics; Brain-Derived Neurotrophic Factor / metabolism; Cell Line, Tumor; Eating / drug effects; Female; Glycosides / administration & dosage; Humans; Male; Melanocortins / metabolism; Models, Animal; Plant Extracts / administration & dosage; Pregnanes / administration & dosage; Rats; Rats, Wistar
TL;DR: The results support the multimodal effects of pregnane glycosides on feeding regulation, which depends on the activity of the melanocortin signaling pathway and BDNF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Biosynthesis of highly enriched C-13-lycopene for human metabolic studies using repeated batch tomato cell culturing with C-13-glucose

FOOD CHEMISTRY, 139(1-4), 631–639.

By: N. Moran*, R. Rogers*, C. Lu*, L. Conlon*, M. Lila n, S. Clinton*, J. Erdman*

author keywords: Carotenoids; Tracers; Lycopene; Tomato; Nutrition; Plant cell culture
MeSH headings : Biological Availability; Carbon Isotopes / metabolism; Carotenoids / biosynthesis; Cells, Cultured; Glucose / chemistry; Glucose / metabolism; Humans; Isotope Labeling; Lycopene; Solanum lycopersicum / chemistry; Solanum lycopersicum / metabolism
TL;DR: An optimised acetone and hexane extraction led to a fourfold increase in lycopene recovery from cultures compared to a standard extraction and an optimised 9-day-long and 18- day-long labelling strategy developed based on glucose utilisation and lycopenes yields yielded (13)C-lycopene with 93% ( 13)C isotopic purity, and 55% of isotopomers were uniformly labelled. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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