Works Published in 2020
Displaying works 121 - 131 of 131 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes
CLINICAL PHARMACOLOGY & THERAPEUTICS, 107(6), 1383–1393.
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents / adverse effects; Antineoplastic Agents / pharmacology; Child; Child, Preschool; Female; Gene Expression Regulation / genetics; Genetic Variation; Genome-Wide Association Study; Genotype; Humans; Hypolipidemic Agents / pharmacology; Infant; Liver / metabolism; Male; Middle Aged; Phenotype; Proprotein Convertase 9 / genetics; Quantitative Trait Loci / genetics; Receptors, G-Protein-Coupled / genetics; Sex Factors; Young Adult
TL;DR:
Translational relevance of these results is evidenced by linking DPYD eQTLs to differences in safety of chemotherapy, linking the sex‐biased regulation of PCSK9 expression to anti‐lipid therapy, and identifying the G‐protein coupled receptor GPR180 as a novel drug target for hypertriglyceridemia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: February 10, 2020
2020 journal article
High-Frequency Irreversible Electroporation Using 5,000-V Waveforms to Create Reproducible 2-and 4-cm Ablation Zones - A Laboratory Investigation Using Mechanically Perfused Liver
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 31(1), 162–168.
MeSH headings : Ablation Techniques / adverse effects; Animals; Electroporation; Liver / injuries; Liver / pathology; Liver / surgery; Perfusion; Sus scrofa; Time Factors
TL;DR:
Investigating if high-frequency irreversible electroporation treatments can be delivered at higher voltages and with greater energy delivery rates than currently implemented in clinical irreversible Electroporation protocols found that H-FIRE treatments can rapidly and reproducibly create 2-cm ablations using an A+GP configuration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: February 3, 2020
2020 journal article
Predicting body mass of bonobos (Pan paniscus) with human-based morphometric equations
AMERICAN JOURNAL OF PRIMATOLOGY, 82(2).
author keywords: allometry; bi-iliac breadth; body size; hominin; panel regression; stature
MeSH headings : Animals; Anthropometry / methods; Body Weight; Democratic Republic of the Congo; Female; Hominidae; Male; Pan paniscus / physiology
TL;DR:
It is found that the novel equation predicts bonobo body mass most accurately overall (41 of 56 bonobos predicted within 20% of their observed body mass) and the novel BMPE is particularly accurate between 25 and 45 kg.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: February 3, 2020
2020 review
The Future of Environmental DNA in Forensic Science
[Review of ]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 86(2).
author keywords: environmental DNA; forensic science; eDNA; metabarcoding; DNA sequencing
MeSH headings : Bacteria / isolation & purification; DNA Barcoding, Taxonomic; DNA, Environmental / analysis; Forensic Sciences / instrumentation; Forensic Sciences / methods; Fungi / isolation & purification; Humans; Microbiota; Plants; Soil Microbiology
TL;DR:
A critical look at the current DNA-based technologies using microbiome and environmental sample sources that are focused on the generation of some investigative tools for use in forensic science and discusses the pitfalls and contentions associated with the use of these techniques.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 3, 2020
2020 journal article
OBJECTIVE GAIT ANALYSIS IN HUMBOLDT PENGUINS (SPHENISCUS HUMBOLDTI) USING A PRESSURE-SENSITIVE WALKWAY
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 50(4), 910–916.
author keywords: Humboldt penguin; lameness; objective gait analysis; pressure-sensitive walkway; Spheniscus humboldti; Tekscan
MeSH headings : Animals; Animals, Zoo; Biomechanical Phenomena; Female; Gait; Gait Analysis / instrumentation; Gait Analysis / methods; Gait Analysis / veterinary; Male; Spheniscidae / physiology
TL;DR:
Assessment of pododermatitis, osteoarthritis, and other causes of lameness in penguins can be challenging and a pressure-sensitive walkway (PSW) allows for objective gait analysis and assessment of analgesic therapeutic response.
(via Semantic Scholar)
Source: Web Of Science
Added: January 27, 2020
2020 journal article
Sterility and concentration of liposomal bupivacaine single-use vial when used in a multiple-dose manner
VETERINARY SURGERY, 49(4), 772–777.
MeSH headings : Anesthesia, Local / methods; Anesthesia, Local / veterinary; Anesthetics, Local / analysis; Anesthetics, Local / therapeutic use; Bupivacaine / analysis; Bupivacaine / therapeutic use; Drug Contamination; Drug Storage
TL;DR:
Single-use liposomal bupivacaine liposome injectable suspension used in a multiple-dose fashion for 5 days yielded no bacterial growth and remained sterile for 5 days when aseptic technique was used.
(via Semantic Scholar)
Source: Web Of Science
Added: January 27, 2020
2020 chapter
Chapter 19 - Immunology
In The Zebrafish in Biomedical Research.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: December 20, 2019
2020 journal article
Efficacy study of a topical treatment with a plant extract with antibiofilm activities using an in vivo model of canine superficial pyoderma
VETERINARY DERMATOLOGY, 31(2), 86–89.
MeSH headings : Administration, Topical; Animals; Anti-Bacterial Agents / administration & dosage; Biofilms / drug effects; Cross-Over Studies; Disease Models, Animal; Dog Diseases / drug therapy; Dogs; Female; Male; Microbial Sensitivity Tests; Plant Extracts / administration & dosage; Proof of Concept Study; Pyoderma / drug therapy; Pyoderma / veterinary; Skin / microbiology; Skin / pathology; Staphylococcus / drug effects
TL;DR:
Topical application of W16P576 markedly reduced lesion development in this proof of principle study and clinical trials are warranted to estimate benefits for dogs with naturally occurring pyoderma under field conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 2, 2019
2020 journal article
Role of electrolyte concentrations and renin‐angiotensin‐aldosterone activation in the staging of canine heart disease
Journal of Veterinary Internal Medicine.
author keywords: ACVIM; congestive heart failure; diuretic; refractory
MeSH headings : Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Diuretics / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / metabolism; Dogs; Electrolytes / blood; Heart Diseases / classification; Heart Diseases / drug therapy; Heart Diseases / metabolism; Heart Diseases / veterinary; Kidney Function Tests; Pyridazines / therapeutic use; Renin-Angiotensin System / physiology; Spironolactone / therapeutic use
TL;DR:
Hypochloremia is a useful marker for stage D HD in dogs, and greater RAAS inhibition in stage D versus stage C indicates effectiveness of RAAS‐suppressive treatments in this group of dogs with refractory CHF.
(via Semantic Scholar)
onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: November 27, 2019
2020 journal article
A preoperative bupivacaine retrobulbar block offers superior antinociception compared with an intraoperative splash block in dogs undergoing enucleation
VETERINARY OPHTHALMOLOGY, 23(2), 225–233.
author keywords: analgesia; bupivacaine; dogs; enucleation; retrobulbar block; splash block
MeSH headings : Anesthetics, Local / administration & dosage; Anesthetics, Local / pharmacology; Animals; Bupivacaine / administration & dosage; Bupivacaine / pharmacology; Dog Diseases / surgery; Dogs; Double-Blind Method; Eye Enucleation / veterinary; Female; Intraoperative Care; Male; Nerve Block / methods; Nerve Block / veterinary; Pain, Postoperative / prevention & control; Preoperative Care
TL;DR:
Preoperative retrobulbar block bupvacaine is more effective than an iSB bupivacaine at controlling both intraoperative and postoperative nociception in dogs undergoing enucleation.
(via Semantic Scholar)
Source: Web Of Science
Added: October 21, 2019
2020 journal article
The impact of tongue dimension on air volume in brachycephalic dogs
VETERINARY SURGERY, 49(3), 512–520.
MeSH headings : Airway Obstruction / etiology; Airway Obstruction / veterinary; Animals; Body Weight; Case-Control Studies; Dogs / anatomy & histology; Female; Male; Nasopharynx / anatomy & histology; Oropharynx / anatomy & histology; Palate, Soft / anatomy & histology; Skull / anatomy & histology; Tomography, X-Ray Computed / veterinary; Tongue / anatomy & histology
TL;DR:
A relative macroglossia was detected in brachycephalic dogs along with reduced air volume in the upper airway, and the tongue was approximately 10 times denser inBrachycephalics dogs than in mesaticephalic dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 26, 2019
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