Works Published in 2011
Displaying works 201 - 220 of 225 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 article
comK Prophage Junction Fragments as Markers for Listeria monocytogenes Genotypes Unique to Individual Meat and Poultry Processing Plants and a Model for Rapid Niche-Specific Adaptation, Biofilm Formation, and Persistence (vol 77, pg 3279, 2011)
Verghese, B., Lok, M., Wen, J., Alessandria, V., Chen, Y., Kathariou, S., & Knabel, S. (2011, July). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 77, pp. 5064–5064.
TL;DR:
This research presents a novel and scalable approach to farming that combines horizontal and vertical integration that addresses the challenges of horizontal integration in the field of food safety and nutrition.
(via Semantic Scholar)
aem.asm.org (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Refining tumor-associated aneuploidy through 'genomic recoding' of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas
LEUKEMIA & LYMPHOMA, 52(7), 1321–1335.
author keywords: Comparative genomic hybridization (CGH); canine; lymphoma; chromosome; microarray
MeSH headings : Aneuploidy; Animals; Breeding; Comparative Genomic Hybridization; Cyclin-Dependent Kinase Inhibitor p16 / genetics; DNA Copy Number Variations / genetics; Dogs; Gene Expression Regulation, Neoplastic; Genomics; Immunophenotyping; Lymphoma, Non-Hodgkin / genetics; Lymphoma, Non-Hodgkin / pathology
TL;DR:
It is hypothesized that the restricted genetic variation of purebred dogs, combined with the contrasting architecture of the human and canine karyotypes, will increase the penetrance of fundamental NHL-associated chromosomal aberrations in both species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Physiologically Based Pharmacokinetic Modeling of Fetal and Neonatal Manganese Exposure in Humans: Describing Manganese Homeostasis during Development
TOXICOLOGICAL SCIENCES, 122(2), 297–316.
author keywords: manganese; potentially susceptible subpopulation; environmental exposure to Mn; formula; fetus; neonate
MeSH headings : Adult; Animals; Child, Preschool; Female; Fetus / drug effects; Fetus / metabolism; Homeostasis; Humans; Infant; Inhalation Exposure; Lactation; Male; Manganese / blood; Manganese / pharmacokinetics; Manganese / toxicity; Maternal Exposure; Milk, Human / chemistry; Models, Biological; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Tissue Distribution
TL;DR:
A physiologically based pharmacokinetic model for Mn during human gestation and lactation was developed to predict Mn in fetal and neonatal brain using a parallelogram approach based upon extrapolation across life stages in rats and cross-species extrapolation to humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Performance Characteristics of a New Hybrid Quadrupole Time-of-Flight Tandem Mass Spectrometer (TripleTOF 5600)
ANALYTICAL CHEMISTRY, 83(13), 5442–5446.
MeSH headings : Fungal Proteins / metabolism; Proteome; Saccharomyces cerevisiae / metabolism; Tandem Mass Spectrometry / instrumentation; Trypsin / metabolism
TL;DR:
The TripleTOF 5600 System, a hybrid quadrupole time-of-flight mass spectrometer, was evaluated to explore the key figures of merit in generating peptide and protein identifications that included spectral acquisition rates, data quality, proteome coverage, and biological depth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Genetic differentiation across North America in the generalist moth Heliothis virescens and the specialist H. subflexa
Molecular Ecology, 20(13), 2676–2692.
author keywords: host plant distribution; metapopulation; population structure; structurama
MeSH headings : Amplified Fragment Length Polymorphism Analysis; Analysis of Variance; Animals; Bayes Theorem; Biological Evolution; DNA / genetics; Feeding Behavior / physiology; Female; Genetic Drift; Genetic Variation / genetics; Genetics, Population; Genotype; Host-Parasite Interactions / genetics; Larva / genetics; Larva / physiology; Male; Moths / classification; Moths / genetics; Moths / physiology; North America; Phenotype; Plants / parasitology; Population Dynamics; Species Specificity
TL;DR:
The finding that the specialist shows more population differentiation than the generalist corroborates the notion that host specialization is not an evolutionary dead end but a dynamic trait.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Complete Genome Sequence of the Thermophilic Bacterium Exiguobacterium sp AT1b
JOURNAL OF BACTERIOLOGY, 193(11), 2880–2881.
MeSH headings : Bacillales / genetics; Bacillales / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Environmental Microbiology; Genome, Bacterial; Hot Temperature; Molecular Sequence Data; Sequence Analysis, DNA
TL;DR:
The genome of strain Exiguobacterium sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Characterization of natural organic matter adsorption in granular activated carbon adsorbers
WATER RESEARCH, 45(13), 3951–3959.
Contributors: S. Velten*, D. Knappe n, J. Traber*, H. Kaiser*, U. Gunten *, M. Boller *, S. Meylan*
author keywords: Adsorption; Granular activated carbon; Natural organic matter (NOM); NOM characterization; Size exclusion chromatography
MeSH headings : Adsorption; Charcoal / chemistry; Chromatography, Gel; Organic Chemicals / chemistry; Organic Chemicals / isolation & purification; Water Pollutants, Chemical / chemistry; Water Pollutants, Chemical / isolation & purification; Water Purification / methods
TL;DR:
In both GAC adsorbers, adsorbability of the remaining NOM fractions, compared on the basis of partition coefficients, increased with decreasing molecular size, suggesting that increasingly larger portions of the internal GAC surface area could be accessed as the size of NOM decreased.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
A Spatial Dirichlet Process Mixture Model for Clustering Population Genetics Data
BIOMETRICS, 67(2), 381–390.
author keywords: Bayesian nonparametrics; Dirichlet process prior; Landscape genetics; Microsatellite data; Model-based clustering
MeSH headings : Algorithms; Animals; Bayes Theorem; Cluster Analysis; Computer Simulation; Genetics, Population / methods; Microsatellite Repeats; Montana; Mustelidae / genetics
TL;DR:
A Bayesian clustering algorithm based on the Dirichlet process prior that uses both genetic and spatial information to classify individuals into homogeneous clusters for further study is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
The impact of neonatal bisphenol-A exposure on sexually dimorphic hypothalamic nuclei in the female rat
NEUROTOXICOLOGY, 32(1), 38–49.
author keywords: Xenoestrogen; Endocrine disruption; Brain; Sexual differentiation; Development; Estrogen receptor; Neuroendocrine
MeSH headings : Age Factors; Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus / drug effects; Arcuate Nucleus of Hypothalamus / growth & development; Benzhydryl Compounds; Body Weight / drug effects; Body Weight / physiology; Female; Phenols / toxicity; Preoptic Area / drug effects; Preoptic Area / growth & development; Rats; Rats, Long-Evans; Sex Characteristics; Sexual Behavior, Animal / drug effects; Sexual Behavior, Animal / physiology; Ventromedial Hypothalamic Nucleus / drug effects; Ventromedial Hypothalamic Nucleus / growth & development
TL;DR:
The results of this and a prior study indicate that the impact of neonatal BPA Exposure within the female rat hypothalamus is region specific and support the hypothesis that developmental BPA exposure may adversely affect reproductive development in females.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 article
John Bennett Fenn (1917-2010)
Muddiman, D. C. (2011, January 14). SCIENCE, Vol. 331, pp. 160–160.
MeSH headings : Chemistry / history; History, 20th Century; History, 21st Century; Nobel Prize; Spectrometry, Mass, Electrospray Ionization / history; United States
TL;DR:
The Nobel Prize in Chemistry did not define John Fenn, nor did it change him; he was the same man before and after, always showing a strong sense of humility.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species
BMC BIOCHEMISTRY, 12.
MeSH headings : Animals; Bile Acids and Salts / metabolism; Evolution, Molecular; Humans; Ligands; Mice; Models, Molecular; Pregnane X Receptor; Protein Interaction Domains and Motifs; Rats; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Receptors, Cytoplasmic and Nuclear / genetics; Receptors, Cytoplasmic and Nuclear / metabolism; Receptors, Steroid / genetics; Receptors, Steroid / metabolism; Species Specificity; Structure-Activity Relationship; Tetraodontiformes; Zebrafish
TL;DR:
These studies provide further evidence of the relationship between both FXR, PXR, and VDR ligand selectivity and cross-species variation in bile salt profiles and suggest a ligand-binding pocket architecture more similar to human and rat FXRs than to lamprey or zebrafish FXRs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Population Genetic Structure in German Cockroaches (Blattella Germanica): Differentiated Islands in an Agricultural Landscape
Journal of Heredity, 102(2), 175–183.
author keywords: Blattella germanica; commensal; Genetic bottleneck; human-mediated dispersal; microsatellite DNA profiling; population structure
MeSH headings : Agriculture; Animals; Bayes Theorem; Blattellidae / genetics; Genetic Variation; Genetics, Population; Genotype; Geography; Insect Control; Microsatellite Repeats / genetics; North Carolina; Phylogeny
TL;DR:
Results reveal that structure of cockroach populations will be genetically structured based on association to a specific management company of origin, but instead it may be regional and influenced strongly by the unintentional movement of cockroaches by farm workers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Endocrine Disruption of Brain Sexual Differentiation by Developmental PCB Exposure
ENDOCRINOLOGY, 152(2), 581–594.
MeSH headings : Animals; Estrogen Receptor alpha / metabolism; Female; Gonadotropin-Releasing Hormone / metabolism; Immunohistochemistry; Insulin-Like Growth Factor I / genetics; Kisspeptins; Male; Neurosecretory Systems / drug effects; Polychlorinated Biphenyls / pharmacology; Polymerase Chain Reaction; Pregnancy; Preoptic Area; Proteins / metabolism; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Androgen / genetics; Receptors, N-Methyl-D-Aspartate / genetics; Sex Differentiation / drug effects; Transforming Growth Factor beta / genetics
TL;DR:
The hypothesis that perinatal exposure to polychlorinated biphenyls (PCBs) that disrupt hormonal pathways would perturb reproductive maturation and the sexually dimorphic development of neuroendocrine systems in the preoptic area (POA) is tested and data suggest that developmental PCBs profoundly impair the sexual differentiation of the female hypothalamus.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Bayesian geostatistical modelling with informative sampling locations
BIOMETRIKA, 98(1), 35–48.
author keywords: Cox process; Gaussian process; Joint model; Point pattern; Posterior consistency; Preferential sampling
TL;DR:
A Bayesian approach is proposed, which models the locations using a log Gaussian Cox process, while modelling the outcomes conditionally on the locations as Gaussian with a Gaussian process spatial random effect and adjustment for the location intensity process.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
BCR-ABL translocation in a dog with chronic monocytic leukemia
VETERINARY CLINICAL PATHOLOGY, 40(1), 40–47.
author keywords: FISH; flow cytometry; monocytosis; myeloproliferative disorder
MeSH headings : Animals; Bone Marrow Cells / pathology; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Flow Cytometry / veterinary; Leukemia, Myeloid / diagnosis; Leukemia, Myeloid / genetics; Leukemia, Myeloid / pathology; Leukemia, Myeloid / veterinary; Translocation, Genetic / genetics
TL;DR:
Clinical and laboratory findings and the protracted course supported a diagnosis of chronic monocytic leukemia (CMoL), the first case of CMoL with a BCR-ABL chromosomal abnormalitiy described in dogs, and may have clinical implications for treatment of dogs with chronic leukemias associated with particular genetic mutations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Aryl hydrocarbon receptor activation in lactotropes and gonadotropes interferes with estradiol-dependent and -independent preprolactin, glycoprotein alpha and luteinizing hormone beta gene expression
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 333(2), 151–159.
author keywords: Dioxin; Ahr; Antiestrogen; Prl; LH; Estradiol
MeSH headings : Animals; Aryl Hydrocarbon Hydroxylases / genetics; Aryl Hydrocarbon Hydroxylases / metabolism; Cytochrome P-450 CYP1A1 / genetics; Cytochrome P-450 CYP1A1 / metabolism; Cytochrome P-450 CYP1A2 / genetics; Cytochrome P-450 CYP1A2 / metabolism; Cytochrome P-450 CYP1B1; Estradiol / pharmacology; Estrogen Receptor alpha / genetics; Estrogen Receptor alpha / metabolism; Female; Gene Expression Regulation / drug effects; Glycoprotein Hormones, alpha Subunit / genetics; Glycoprotein Hormones, alpha Subunit / metabolism; Gonadotrophs / cytology; Gonadotrophs / drug effects; Gonadotrophs / metabolism; Immunohistochemistry; In Situ Hybridization; Lactotrophs / cytology; Lactotrophs / drug effects; Lactotrophs / metabolism; Luteinizing Hormone, beta Subunit / genetics; Luteinizing Hormone, beta Subunit / metabolism; Pituitary Gland / cytology; Pituitary Gland / drug effects; Pituitary Gland / enzymology; Polychlorinated Dibenzodioxins / pharmacology; Prolactin / genetics; Prolactin / metabolism; Protein Precursors / genetics; Protein Precursors / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon / genetics; Receptors, Aryl Hydrocarbon / metabolism
TL;DR:
It is found that TCDD upregulated known AhR target genes, cytochrome p450 1a1 (Cyp1a1), Cyp1a2 and Cyp1b1 in the rat pituitary gland, and complex interactions between Ahr and Esr alter Prl and luteinizing hormone (LH) synthesis by direct actions in lactotropes and gonadotropes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 review
The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities
[Review of ]. IMMUNOGENETICS, 63(3), 123–141.
author keywords: Marsupial; Monotreme; Chicken; Xenopus; Zebrafish; Innate immunity; Cytotoxicity
MeSH headings : Animals; Evolution, Molecular; Humans; Immunity, Innate; Killer Cells, Natural / immunology; Mammals / genetics; Mammals / immunology; Phylogeny; Receptors, Natural Killer Cell / genetics; Receptors, Natural Killer Cell / immunology; Receptors, Natural Killer Cell / metabolism; Vertebrates / genetics; Vertebrates / immunology
TL;DR:
Several lines of evidence suggest that NK-type function or its equivalent has sustained a long evolutionary history throughout vertebrate species and likely reflects the influence of pathogens on their evolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Molecular characterization of two isoforms of piscidin 4 from the hybrid striped bass (Morone chrysops x Morone saxatilis)
FISH & SHELLFISH IMMUNOLOGY, 30(1), 420–424.
author keywords: Antimicrobial peptides; Piscidin 4; Isoforms; Hybrid striped bass
MeSH headings : Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides / genetics; Antimicrobial Cationic Peptides / metabolism; Base Sequence; Bass / genetics; Bass / metabolism; Hybridization, Genetic; Molecular Sequence Data; Protein Isoforms
TL;DR:
Small, linear, a-helical, amphipathic polypeptides in this class are the piscidins, components of innate immunity, which serve as a first line of defense against potential pathogens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Insects in confined swine operations carry a large antibiotic resistant and potentially virulent enterococcal community
BMC Microbiology, 11(1), 23.
MeSH headings : Animals; Cockroaches / microbiology; Drug Resistance, Multiple, Bacterial / genetics; Electrophoresis, Gel, Pulsed-Field; Enterococcus / drug effects; Enterococcus / genetics; Enterococcus / pathogenicity; Enterococcus faecalis / drug effects; Enterococcus faecalis / genetics; Enterococcus faecalis / pathogenicity; Genotype; Houseflies / microbiology; Phenotype; Swine; Virulence / genetics
TL;DR:
This study shows that house flies and German cockroaches in the confined swine production environment likely serve as vectors and/or reservoirs of antibiotic resistant and potentially virulent enterococci and consequently may play an important role in animal and public health.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
FLT3 mutations in canine acute lymphocytic leukemia
BMC CANCER, 11.
MeSH headings : Amino Acid Sequence; Animals; Blotting, Western; Carbazoles / pharmacology; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; DNA Mutational Analysis; DNA, Neoplasm / chemistry; DNA, Neoplasm / genetics; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases / metabolism; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Mutation; Phosphorylation / drug effects; Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism; Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology; Reverse Transcriptase Polymerase Chain Reaction; STAT5 Transcription Factor / metabolism; fms-Like Tyrosine Kinase 3 / antagonists & inhibitors; fms-Like Tyrosine Kinase 3 / genetics; fms-Like Tyrosine Kinase 3 / metabolism
TL;DR:
Results show that ALL andFLT3 biology is conserved between canine and human patients, supporting the notion that canine ALL, in conjunction with the GL-1 cell line, will be useful in the development of a relevant large animal model to aid in the study of human FLT3 mutant leukemias.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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