Works Published in 2020
Displaying works 21 - 40 of 99 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Methods for Cryosectioning and Mass Spectrometry Imaging of Whole-Body Zebrafish
Journal of the American Society for Mass Spectrometry, 31(4), 768–772.
author keywords: zebrafish; mass spectrometry imaging; cryosectioning; IR-MALDESI; lipids
MeSH headings : Animals; Cryoultramicrotomy / methods; Lipids / analysis; Male; Molecular Imaging; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Zebrafish / metabolism
TL;DR:
The zebrafish (Danio rerio) is an ideal model for whole animal studies of lipid metabolism and lipid-related disease, and infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) mass spectrometry imaging (MSI) was applied for direct visualization of lipid and metabolite distributions across various organs in whole-body zebra fish tissue sections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 6, 2021
2020 journal article
From Pesticides to Per- and Polyfluoroalkyl Substances: An Evaluation of Recent Targeted and Untargeted Mass Spectrometry Methods for Xenobiotics.
Analytical Chemistry.
MeSH headings : Fluorocarbons / analysis; Mass Spectrometry; Xenobiotics / analysis
www.ncbi.nlm.nih.gov (repository)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: ORCID
Added: February 4, 2021
2020 journal article
Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies
REPRODUCTIVE TOXICOLOGY, 98, 29–60.
Contributors: J. Heindel*, S. Belcher n , J. Flaws *, G. Prins *, S. Ho*, J. Mao*, H. Patisaul n , W. Ricke*
author keywords: CLARITY-BPA; Guideline study; Bisphenol A; EDC; Endocrine disruptor; GLP; Systemic effects
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; DNA Methylation; Endocrine Disruptors / toxicity; Female; Gene Expression Regulation, Developmental / drug effects; Heart / drug effects; Heart / growth & development; Male; Mammary Glands, Animal / drug effects; Mammary Glands, Animal / growth & development; Maternal-Fetal Exchange; Ovary / drug effects; Ovary / growth & development; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Prostate / drug effects; Prostate / growth & development; Rats, Sprague-Dawley; Reproducibility of Results; Thyroid Gland / drug effects; Thyroid Gland / growth & development; Urethra / drug effects; Urethra / growth & development
TL;DR:
The goal of this collaboration was to provide a more comprehensive dataset upon which to base safety standards and to determine whether industry-standard tests are as sensitive and predictive as molecular and disease-associated endpoints.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
9. Industry, Innovation and Infrastructure
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 19, 2021
2020 journal article
Thyroid Receptor Antagonism of Chemicals Extracted from Personal Silicone Wristbands within a Papillary Thyroid Cancer Pilot Study
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 54(23), 15296–15312.
MeSH headings : Adult; Antithyroid Agents; Case-Control Studies; Environmental Monitoring; Flame Retardants / analysis; HEK293 Cells; Halogenated Diphenyl Ethers / analysis; Humans; North Carolina; Pilot Projects; Prospective Studies; Silicones; Thyroid Cancer, Papillary; Thyroid Neoplasms
TL;DR:
The results suggest that personal passive samplers may be useful in evaluating the bioactivities of mixtures that people contact on a daily basis and tentative associations between thyroid receptor antagonism, chemical concentrations, and papillary thyroid cancer case status are reported.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021
2020 journal article
Rapid Characterization of Emerging Per- and Polyfluoroalkyl Substances in Aqueous Film-Forming Foams Using Ion Mobility Spectrometry-Mass Spectrometry
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 54(23), 15024–15034.
MeSH headings : Fluorocarbons / analysis; Ion Mobility Spectrometry; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical / analysis
TL;DR:
This work demonstrates that LC-IMS-MS-enabled untargeted analysis of complex formulations, followed by feature identification using data-processing algorithms, can be used for rapid exposure characterization of known and putative PFAS during fire suppression-related contamination events.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021
2020 journal article
A Versatile Platform for Mass Spectrometry Imaging of Arbitrary Spatial Patterns
Journal of the American Society for Mass Spectrometry, 31(12), 2547–2552.
author keywords: Mass Spectrometry Imaging; Arbitrary Region of Interest; MALDESI; Vision-System
TL;DR:
A vision-system driven platform, RastirX, has been constructed for mass spectrometry imaging (MSI) of arbitrary two-dimensional patterns that reduces contamination from off-sample material and significantly reduces acquisition time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: January 19, 2021
2020 journal article
Unveiling molecular signatures of preeclampsia and gestational diabetes mellitus with multi-omics and innovative cheminformatics visualization tools
MOLECULAR OMICS, 16(6).
MeSH headings : Case-Control Studies; Diabetes, Gestational / genetics; Female; Genomics; Humans; Lipidomics; Metabolic Networks and Pathways; Pre-Eclampsia / genetics; Pregnancy
TL;DR:
The multi-omic evaluations performed here provide new insight into the end-stage molecular profiles of each disease, thereby supplying information potentially crucial for earlier diagnosis and treatments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 4, 2021
2020 journal article
From Prevention to Disease Perturbations: A Multi-Omic Assessment of Exercise and Myocardial Infarctions
Biomolecules.
author keywords: lipidomics; metabolomics; multi-omics; planned myocardial infarction (PMI); myocardial infarction (MI); exercise; heart; cheminformatics
MeSH headings : Exercise; Exercise Test; Female; Humans; Lipidomics; Lipids / blood; Lipids / genetics; Male; Metabolomics; Middle Aged; Myocardial Infarction / blood; Myocardial Infarction / genetics; Myocardial Infarction / physiopathology; Myocardial Infarction / prevention & control; Risk Factors
TL;DR:
Different lipidomic perturbations were observed for these events, as could be expected from their vastly different stresses on the body, and these results were combined with previously published metabolomic characterizations of the same patients to give a more holistic understanding of the molecular changes associated with each.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: January 4, 2021
2020 review
Emerging lanthanum (III)-containing materials for phosphate removal from water: A review towards future developments
[Review of ]. ENVIRONMENT INTERNATIONAL, 145.
author keywords: Lanthanum; Lanthanum-containing materials; Phosphate; Surface water restoration; Eutrophication control; Phosphorus inactivation
MeSH headings : Adsorption; Kinetics; Lanthanum; Phosphates; Prospective Studies; Water; Water Pollutants, Chemical
TL;DR:
The main benefits of lanthanum (III)-containing materials for phosphate removal are their ability to strongly bind phosphate under diverse environmental conditions and their ability for long-term exposures on ecological organisms, particularly primary producers and benthic organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: December 21, 2020
2020 journal article
Energetics as a lens to understanding aquatic insect's responses to changing temperature, dissolved oxygen and salinity regimes
CURRENT OPINION IN INSECT SCIENCE, 41, 46–53.
MeSH headings : Animals; Aquatic Organisms / physiology; Insecta / physiology; Oxygen / analysis; Salinity; Stress, Physiological; Temperature; Water / chemistry
TL;DR:
Recent developments in understanding of how high temperatures, elevated salinities and low oxygen levels affect physiological processes, responses at the organismal level, and impacts on species interaction and community assembly are highlighted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: December 14, 2020
2020 journal article
Effects of Prenatal Exposure to a Mixture of Organophosphhate Flame Ritardants on Placental Gene Expression and Serotonergic Innervaion in the Fetal Rat Brain
TOXICOLOGICAL SCIENCES, 176(1), 203–223.
author keywords: endocrine disruptors; endocrine toxicology; flame retardants; metabolome; neurotoxicity; developmental; neurotoxicology; neurotransmitter; developmental toxicity; prenatal; reproductive and developmental toxicology; developmental/teratology
MeSH headings : Animals; Brain / drug effects; Female; Fetal Development; Fetus; Flame Retardants / toxicity; Gene Expression; Humans; Male; Organophosphates; Organophosphorus Compounds; Placenta / metabolism; Plasticizers; Polybrominated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Serotonin / metabolism
TL;DR:
Findings suggest that OPFRs have the potential to impact the 5-HTergic system in the fetal forebrain by disrupting placental Trp metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 14, 2020
2020 journal article
Leveraging the Comparative Toxicogenomics Database to Fill in Knowledge Gaps for Environmental Health: A Test Case for Air Pollution-induced Cardiovascular Disease
TOXICOLOGICAL SCIENCES, 177(2), 392–404.
author keywords: environmental health; chemical-induced pathways; air pollution; cardiovascular disease; database
MeSH headings : Air Pollutants / toxicity; Air Pollution; Cardiovascular Diseases / chemically induced; Environmental Exposure; Environmental Health; Humans; Toxicogenetics
TL;DR:
This paper systematically compute the genes, molecular mechanisms, and biological events for the environmental health association linking air pollution toxicants with two cardiovascular diseases as a test case and identifies 19 genes and 96 phenotypes shared between these two air pollutant-induced outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: December 14, 2020
2020 journal article
Treating water containing elevated bromide and iodide levels with granular activated carbon and free chlorine: impacts on disinfection byproduct formation and calculated toxicity
ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY, 6(12), 3460–3475.
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 11, 2020
2020 journal article
The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity
REPRODUCTIVE TOXICOLOGY, 96, 359–369.
author keywords: Developmental toxicity; Flame retardants; Benchmark dose; Lowest effect concentration; Neurotoxicity; Classification model
MeSH headings : Animals; Embryo, Nonmammalian; Embryonic Development / drug effects; Flame Retardants / toxicity; Models, Animal; Neurotoxicity Syndromes; Risk Assessment; Structure-Activity Relationship; Teratogens / chemistry; Teratogens / toxicity; Zebrafish
TL;DR:
Developmental zebrafish were sufficiently sensitive at detecting FRC structure-bioactivity impacts that this work illustrates the power of a multi-dimensional in vivo platform to expand the ability to predict the hazard potential of new compounds based on structural relatedness, ultimately leading to reliable toxicity predictions based on chemical structure.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 30, 2020
2020 journal article
Transcriptomic and life history responses of the mayfly Neocloeon triangulifer to chronic diel thermal challenge
SCIENTIFIC REPORTS, 10(1).
MeSH headings : Animals; Ephemeroptera / genetics; Ephemeroptera / physiology; Gene Expression Regulation; Heat-Shock Response / genetics; Heat-Shock Response / physiology; Temperature; Transcriptome
TL;DR:
The chronically stressed population had reduced expression of transcripts related to ATP synthesis, mitochondrial electron chain functions, gluconeogenesis and glycolytic processes while transcripts associated with cell adhesion, synaptic vesicle transport, regulation of membrane potential and lipid biosynthesis increased.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: November 30, 2020
2020 journal article
Application of LCA modelling in integrated waste management
WASTE MANAGEMENT, 118, 313–322.
author keywords: LCA; Waste management; Modelling
MeSH headings : Environment; Policy Making; Prospective Studies; Refuse Disposal; Waste Management
TL;DR:
Six areas where LCA is expected to play a role in waste management in the future are described: understanding an existing waste management system; improving existing wastemanagement systems; comparing alternative technologies/ technology performance; 4) technology development/prospective technologies; 5) policy development/strategic development; and 6) reporting.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020
2020 journal article
Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems
ANALYST, 145(22), 7197–7209.
MeSH headings : Cheminformatics; Lipidomics; Lipids; Mass Spectrometry; Phenotype
TL;DR:
A Structural-based Connectivity and Omic Phenotype Evaluations (SCOPE) cheminformatics toolbox to aid in these evaluations of lipid species and their respective biological roles is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020
2020 journal article
3D Imaging and metabolomic profiling reveal higher neuroactive kavalactone contents in lateral roots and crown root peels of Piper methysticum (kava)
GIGASCIENCE, 9(9).
author keywords: kava; kavalactones; metabolomics; 3D imaging; mass spectrometry imaging
MeSH headings : Imaging, Three-Dimensional; Kava; Lactones; Metabolomics; X-Ray Microtomography
TL;DR:
Detailed metabolomic profile and spatio-temporal characteristics of tissues from the roots and stems are characterized using cross-platform metabolomics and a 3D imaging approach to provide mechanistic insights into the social and clinical practice of the use of only peeled roots.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 16, 2020
2020 journal article
Children’s Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals
International Journal of Environmental Research and Public Health, 17(22), 8337.
author keywords: systems approach; children’ s environmental health
TL;DR:
A systems approach is considered to address the complexity of children’s environmental health and the role of exposure to chemicals during early life, in the context of nonchemical stressors, on health outcomes by advancing the tools for integrating more complex information.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: ORCID
Added: November 13, 2020
2020 journal article
Proteomic assessment of serum biomarkers of longevity in older men
AGING CELL, 19(11).
author keywords: aging; biomarker; inflammation; longevity; men; proteomics
MeSH headings : Aged; Biomarkers / blood; Humans; Longevity; Male; Proteomics / methods
TL;DR:
It is suggested that complex pathways, prominently including inflammation, are linked to the likelihood of attaining longevity and may serve to identify novel biomarkers for longevity and to understand the biology underlying lifespan.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 2, 2020
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
