Works Published in 2020
Displaying works 21 - 40 of 50 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 article
Shutting down RNA-targeting CRISPR
Barrangou, R., & Sontheimer, E. J. (2020, July 3). SCIENCE, Vol. 369, pp. 31–32.
MeSH headings : Bacteriophages; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; RNA
TL;DR:
An anti-CRISPR mechanism is reported that inhibits Cas13a RNase activity, with potential utility as a CRISPR effector control switch.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 3, 2020
2020 journal article
Role of sweeteners on temporality and bar hardening of protein bars
JOURNAL OF DAIRY SCIENCE, 103(7), 6032–6053.
MeSH headings : Animals; Flavoring Agents; Food Analysis; Food Storage; Hardness; Humans; Sweetening Agents / analysis; Taste; Time Factors
TL;DR:
Non-nutritive sweeteners did not have a negative effect on bar hardness in low-carbohydrate, high-protein bars and can be applied to commercially produced protein bars for naturally sweetened bars with different protein types without negative effects on protein bar texture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 13, 2020
2020 review
Invited review: Astringency in whey protein beverages
[Review of ]. JOURNAL OF DAIRY SCIENCE, 103(7), 5793–5804.
MeSH headings : Beverages / analysis; Humans; Sensation; Taste; Whey Proteins / chemistry
TL;DR:
Astringency is the sensation of mouth drying and puckering, and it has also been described as a loss of lubrication in the mouth, which limits whey protein ingredient applications because astringency is undesirable to consumers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: July 13, 2020
2020 journal article
The effects of fungal lipase-treated milk lipids on bread making
LWT-FOOD SCIENCE AND TECHNOLOGY, 128.
Contributors: Z. Huang *, C. Brennan *, H. Zheng n , M. Mohan *, L. Stipkovits*, W. Liu *, D. Kulasiri *, W. Guan *, H. Zhao *, J. Liu*
author keywords: Rheological characteristics; Texture profile analysis (TPA); Glycaemic response; Complexing index; Anti-staling
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 6, 2020
2020 article
Celebrating reviewers-The 2020 Manfred Kroger Outstanding Reviewer Award winner
Foegeding, E. A. (2020, June). JOURNAL OF FOOD SCIENCE, Vol. 85, pp. 1618–1618.
onlinelibrary.wiley.com (publisher PDF)
Source: Web Of Science
Added: June 29, 2020
2020 article
Dear authors, reviewers, and editors: Thank you!
Foegeding, E. A. (2020, May). JOURNAL OF FOOD SCIENCE, Vol. 85, pp. 1383–1383.
Source: Web Of Science
Added: June 8, 2020
2020 journal article
Fabrication and assessment of milk phospholipid-complexed antioxidant phytosomes with vitamin C and E: A comparison with liposomes
FOOD CHEMISTRY, 324.
Contributors: Z. Huang *, C. Brennan *, H. Zhao *, J. Liu*, W. Guan *, M. Mohan *, L. Stipkovits*, H. Zheng n , D. Kulasiri *
author keywords: Milk phospholipids; Phytosome; Liposome; Encapsulation efficiency; In vitro digestion; Cellular uptake
MeSH headings : Animals; Antioxidants / chemistry; Ascorbic Acid / chemistry; Ascorbic Acid / pharmacokinetics; Calorimetry, Differential Scanning; Cell Line; Drug Liberation; Epithelial Cells / drug effects; Hydrogen Bonding; Intestinal Absorption / drug effects; Liposomes / chemistry; Milk / chemistry; Phospholipids / chemistry; Phospholipids / pharmacokinetics; Rats; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; alpha-Tocopherol / chemistry
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 1, 2020
2020 journal article
Comprehensive Mining and Characterization of CRISPR-Cas Systems in Bifidobacterium
Microorganisms, 8(5), 720.
author keywords: Bifidobacterium; CRISPR-Cas; genomics
TL;DR:
This study mined 954 publicly available Bifidobacterium genomes and identified CRIPSR-Cas systems in 57% of these strains, and characterized the CRISPR RNA, tracrRNA, and PAM sequences to provide a molecular basis for the development of new genome editing tools for a variety of applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: ORCID
Added: May 29, 2020
2020 journal article
Applications of CRISPR-Cas systems in lactic acid bacteria
FEMS Microbiology Reviews, 44(5), 523–537.
author keywords: Lactic acid bacteria; CRISPR; Cas; genome editing; probiotics; genomics
MeSH headings : CRISPR-Cas Systems; Industrial Microbiology / trends; Lactobacillales / genetics; Microbiota / genetics
TL;DR:
CRISPR-Cas classification, overview CRISPR biology and mechanism of action, and current and future applications in lactic acid bacteria are discussed, opening new avenues for their industrial exploitation and manipulation of microbiomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 21, 2020
2020 journal article
Strain-Dependent Inhibition of Clostridioides difficile by Commensal Clostridia Carrying the Bile Acid-Inducible ( bai ) Operon
Journal of Bacteriology, 202(11).
Ed(s): L. Comstock
author keywords: 7 alpha-dehydroxylation; Clostridia; Clostridioides difficile; bile acids; cholate; deoxycholate
MeSH headings : Antibiosis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bile Acids and Salts / metabolism; Clostridiales / genetics; Clostridiales / physiology; Clostridioides difficile / growth & development; Clostridioides difficile / physiology; Clostridium Infections / metabolism; Clostridium Infections / microbiology; Clostridium histolyticum / genetics; Clostridium histolyticum / physiology; Humans; Operon; Species Specificity; Symbiosis
TL;DR:
Four commensal Clostridia that encode the bai operon effect C. scindens have been associated with protection against CDI, however the mechanism for this protection is unknown and competition studies revealed that C. difficile was able to outcompete the commensals in an in vitro co-culture system.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 9, 2020
2020 review
Production of Milk Phospholipid-Enriched Dairy Ingredients
[Review of ]. FOODS, 9(3).
Contributors: Z. Huang *, H. Zheng n , C. Brennan *, M. Mohan *, L. Stipkovits*, L. Li*, D. Kulasiri *
author keywords: milk phospholipids; buttermilk; life-cycle assessment; carbon footprint; supercritical fluid extraction; membrane separation
TL;DR:
This review assessed four typical extraction processes and estimated that the life-cycle carbon footprints of MPLs were 87.40, 170.59, 159.07, and 101.05 kg CO2/kg MPL for membrane separation process, supercritical fluid extraction by CO2 and dimethyl ether (DME), SFE by DME, and organic solvent extraction, respectively.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 8, 2020
2020 review
Combining omics technologies with CRISPR-based genome editing to study food microbes
[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 61, 198–208.
MeSH headings : Bacteria / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Editing; Probiotics
TL;DR:
Current applications of omics technologies in food microorganisms and CRISPR-based genome editing technologies in bacteria are highlighted, and how this integrated approach enables effective engineering of food microbes to generate enhanced probiotic strains, develop novel biotherapeutics and alter microbial communities in food matrices is discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020
2020 journal article
Genomic characterization of Lactobacillus fermentum DSM 20052
BMC Genomics, 21(1).
author keywords: Lactobacillus; Fermentum; Comparative genomics; CRISPR
MeSH headings : CRISPR-Cas Systems / genetics; Genetic Variation; Genome, Bacterial; Genomic Islands; Genomics; Interspersed Repetitive Sequences; Limosilactobacillus fermentum / classification; Limosilactobacillus fermentum / genetics; Phylogeny
TL;DR:
This study genomically characterize L. fermentum using the type strain DSM 20052 as a canonical representative of this species, enabling genomic-informed selection of strains with specific traits for commercial product formulation, and establishes a framework for the functional characterization of features of interest.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: April 30, 2020
2020 article
Understanding and Controlling Food Protein Structure and Function in Foods: Perspectives from Experiments and Computer Simulations
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 365–387.
author keywords: molecular dynamics; coarse graining; rare-event methods; constant-pH simulation; QSAR; GPCR; molecular interactions
MeSH headings : Computer Simulation; Dietary Proteins / administration & dosage; Dietary Proteins / chemistry; Food; Structure-Activity Relationship
TL;DR:
This review highlights several examples of advanced computer simulations at molecular, mesoscale, and multiscale levels that shed light on the mechanisms at play in foods, thereby facilitating their control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 27, 2020
2020 journal article
Deletion of S-Layer Associated Ig-Like Domain Protein Disrupts the Lactobacillus acidophilus Cell Surface
FRONTIERS IN MICROBIOLOGY, 11.
author keywords: Lactobacillus; probiotic; S-layer; cell surface; S-layer associated protein; Ig-like domain
TL;DR:
Identification of similar proteins in alternative bacterial species may help pinpoint next-generation host-adapted probiotic candidates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020
2020 journal article
Comparison of a central location test versus a home usage test for consumer perception of ready-to-mix protein beverages
JOURNAL OF DAIRY SCIENCE, 103(4), 3107–3124.
author keywords: central location test; home usage test; flavor; mouthfeel
MeSH headings : Animals; Beverages / analysis; Cattle / physiology; Consumer Behavior; Female; Flavoring Agents / analysis; Humans; Taste; Vanilla; Viscosity; Whey Proteins / analysis
TL;DR:
It is suggested that a CLT can be used to differentiate consumer acceptance among vanilla-flavored RTM whey protein beverages and a HUT should be used for more intensive insights for mouthfeel and mixing experience-related attributes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 article
CRISPR Shields: Fending Off Diverse Cas Nucleases with Nucleus-like Structures
Barrangou, R., & Sontheimer, E. J. (2020, March 5). MOLECULAR CELL, Vol. 77, pp. 934–936.
MeSH headings : Bacteriophages / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; DNA; RNA
TL;DR:
It is demonstrated that a nucleus-like proteinaceous structure shields phage DNA from CRISPR-associated nucleases encompassing Cascade-Cas3, Cas9, and Cas12.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 6, 2020
2020 journal article
Drivers of liking for Cheddar cheese shreds
JOURNAL OF DAIRY SCIENCE, 103(3), 2167–2185.
author keywords: Cheddar cheese shreds; consumer liking; drivers of liking
MeSH headings : Adult; Animals; Cheese / analysis; Color; Consumer Behavior; Female; Food Preferences; Humans; Male; Middle Aged; Principal Component Analysis; Taste; Whey; Young Adult
TL;DR:
Results from this study can be used to optimize the intrinsic sensory properties of Cheddar cheese shreds, as well as by hot and cold texture attributes and instrumental tests.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials
MBio, 11(2).
Ed(s): J. Ballard
MeSH headings : Animals; Bacteriophages / genetics; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems / genetics; Clostridioides difficile / genetics; Enterocolitis, Pseudomembranous / microbiology; Enterocolitis, Pseudomembranous / therapy; Female; Genetic Engineering; Male; Mice; Mice, Inbred C57BL
TL;DR:
The findings suggest that phage-delivered programmable CRISPR therapeutics have the potential to leverage the specificity and apparent safety of phage therapies and improve their potency and reliability for eradicating specific bacterial species within complex communities, offering a novel mechanism to treat pathogenic and/or multidrug-resistant organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: March 10, 2020
2020 review
Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants
[Review of ]. NATURE REVIEWS MICROBIOLOGY, 18(2), 67–83.
MeSH headings : Archaea / genetics; Bacteria / genetics; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / physiology; Evolution, Molecular; Gene Expression Regulation, Archaeal / physiology; Gene Expression Regulation, Bacterial / physiology
TL;DR:
An updated evolutionary classification of CRISPR–Cas systems and cas genes is provided, with an emphasis on the major developments that have occurred since the publication of the latest classification, in 2015, which includes 2 classes, 6 types and 33 subtypes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 27, 2020
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