Works Published in 2017

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Displaying works 1 - 20 of 37 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 journal article

Rheological, pasting and microstructural studies of dairy protein–starch interactions and their application in extrusion-based products: A review

Starch/Staerke, 69(1-2).

By: L. Kumar*, M. Brennan*, S. Mason*, H. Zheng* & C. Brennan*

Contributors: L. Kumar*, M. Brennan*, S. Mason*, H. Zheng* & C. Brennan*

author keywords: Dairy protein; Extrusion; Protein-starch interactions; Rheology; Starch
Source: ORCID
Added: September 22, 2021

2017 journal article

Les systèmes CRISPR-Cas comme arme contre les bactéries pathogènes

Biologie Aujourd'Hui, 211(4), 265–270.

MeSH headings : Animals; Anti-Bacterial Agents / metabolism; Bacteria / immunology; Bacteria / pathogenicity; CRISPR-Cas Systems / physiology; Cell Death / genetics; Deoxyribonucleases / genetics; Deoxyribonucleases / metabolism; Disease Resistance / genetics; Humans; Immunity, Innate / genetics
TL;DR: These technologies enable the development of novel tools based on CRISPR-Cas systems to specifically eliminate pathogenic bacteria and precisely modify the composition of various microbiomes. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 27, 2020

2017 journal article

Genome Editing of Food-Grade Lactobacilli To Develop Therapeutic Probiotics

Microbiology Spectrum, 5(5).

MeSH headings : Animals; Bacterial Infections / drug therapy; Gene Editing; Genome, Bacterial; Humans; Lactobacillus / genetics; Lactobacillus / physiology; Probiotics / chemistry; Probiotics / therapeutic use
TL;DR: Recent advances in genetic alteration of food-grade bacteria, with a focus on CRISPR-associated enzyme genome editing, single-stranded DNA recombineering, and the modification of bacteriophages are discussed. (via Semantic Scholar)
Source: ORCID
Added: January 3, 2020

2017 journal article

Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum

Frontiers in Microbiology, 8.

author keywords: CRISPR-Cas systems; genotyping; probiotics; Bifidobacterium longum
TL;DR: It is suggested that CRISPR-Cas immune systems are instrumental in mounting diversified viral resistance in B. longum, and hypervariable loci can be used to gain insights into strain origin, evolution and phylogeny, and can provide discriminatory sequences to distinguish even clonal isolates. (via Semantic Scholar)
Source: ORCID
Added: January 3, 2020

2017 journal article

Repurposing CRISPR-Cas systems as DNA-based smart antimicrobials

Cell and Gene Therapy Insights, 3(1), 63–72.

By: R. Barrangou* & D. Ousterout

Source: ORCID
Added: January 2, 2020

2017 article

Immune Loss as a Driver of Coexistence During Host-Phage Coevolution

Weissman, J. L., Holmes, R., Barrangou, R., Moineau, S., Fagan, W. F., Levin, B., & Johnson, P. L. F. (2017, February 3). (Vol. 2). Vol. 2.

Source: ORCID
Added: January 2, 2020

2017 journal article

QnAs with Rodolphe Barrangou

Proceedings of the National Academy of Sciences, 114(28), 7183–7184.

By: P. Nair

MeSH headings : Animals; Bacteria / virology; Biotechnology / history; Biotechnology / methods; Biotechnology / trends; CRISPR-Cas Systems; Drug Resistance, Bacterial; Food Contamination; Food Microbiology; Food Technology; Genotype; History, 21st Century; Livestock; Meat; Molecular Biology
TL;DR: Rodolphe Barrangou furnished experimental proof for the notion that CRISPR confers a form of adaptive immunity that helps bacteria fend off invading viruses, and was honored with 2017 National Academy of Sciences Award in molecular biology. (via Semantic Scholar)
Source: ORCID
Added: January 2, 2020

2017 journal article

On the global CRISPR array behavior in class I systems

Biology Direct.

By: A. Toms n & R. Barrangou n

MeSH headings : CRISPR-Cas Systems / physiology; Chromosomes, Bacterial / chemistry; Datasets as Topic; Genome, Bacterial; Models, Genetic; Poisson Distribution; Software
TL;DR: This study establishes that bacterial Class I CRISPR array size tends to follow a geometric distribution; theseCRISPRs are not randomly distributed along the chromosome; and the CRISpr array closest to the cas genes is typically larger than loci in trans. (via Semantic Scholar)
Source: ORCID
Added: January 2, 2020

2017 journal article

Advances in Industrial Biotechnology Using CRISPR-Cas Systems

Trends in Biotechnology, 8(2), 134–146.

MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Biotechnology / methods; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Endonucleases / genetics; Endonucleases / metabolism; Gene Editing / methods; Genetic Engineering / methods; Industrial Microbiology / methods; Metabolic Networks and Pathways / genetics; Plants / genetics; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / metabolism
TL;DR: The fundamental characteristics of CRISPR-Cas systems are explored and how these features can be used in industrial settings are highlighted. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries
Added: January 2, 2020

2017 article

Sensory Character of Cheese and Its Evaluation

CHEESE: CHEMISTRY, PHYSICS AND MICROBIOLOGY, VOL 1-2, 4TH EDITION, pp. 517–545.

By: M. Drake n & C. Delahunty

Source: Web Of Science
Added: August 6, 2018

2017 review

Using CRISPR-Cas systems as antimicrobials

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 37, 155–160.

MeSH headings : Anti-Infective Agents / pharmacology; Biological Products / pharmacology; CRISPR-Cas Systems; DNA Cleavage; DNA, Bacterial / metabolism; Genetic Engineering; Microbial Viability / drug effects; Plasmids; Transformation, Bacterial
TL;DR: This work discusses how DNA damage introduced by Cas nucleases in bacteria can efficiently and specifically lead to plasmid curing or drive cell death and establishes CRISPR-Cas systems as potent and programmable antimicrobials. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Guest editorial: CRISPRcas9: CRISPR-Cas systems: at the cutting edge of microbiology

Current Opinion in Microbiology, 37, vii-viii.

MeSH headings : Bacteria / genetics; Bacteria / immunology; Biotechnology / trends; CRISPR-Associated Proteins / metabolism; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / immunology; Gene Editing; Microbiology / trends; Quorum Sensing
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2017 review

CRISPR-based engineering of next-generation lactic acid bacteria

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 37, 79–87.

MeSH headings : Bifidobacterium / genetics; Bifidobacterium / physiology; CRISPR-Cas Systems; Food Microbiology / methods; Gene Editing; Humans; Lactobacillus / genetics; Lactobacillus / physiology; Metabolic Engineering; Probiotics
TL;DR: The advent of CRISPR-based technologies has opened new avenues for the development of next-generation food microorganisms and probiotics with enhanced functionalities and can be harnessed to genetically modify probiotics and enhance their therapeutic potential to deliver vaccines or modulate the host immune response. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals

MBIO, 8(6).

Ed(s): E. Martens & M. McFall-Ngai

author keywords: Lactobacillus; beta-glucoside; bioavailability; gut microbiota; phytochemical; polydatin; polyphenols; resveratrol; xenobiotic metabolism
MeSH headings : Biological Availability; Dietary Carbohydrates / metabolism; Gastrointestinal Microbiome / physiology; Glucosides / metabolism; Glucosides / pharmacology; Humans; Hydrolysis; Lactobacillus acidophilus / drug effects; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / metabolism; Phytochemicals / metabolism; Polyphenols / metabolism; Resveratrol; Stilbenes / metabolism
TL;DR: This work demonstrates the growth of Lactobacillus acidophilus on mono- and diglucosyl dietary plant glycosides (PGs) possessing small aromatic aglycones and highlights an important role of lactobacilli in the bioconversion of dietary PG and presents a framework from which to derive molecular insights into their metabolism by members of the human gut microbiota. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

A 100-Year Review: Sensory analysis of milk

JOURNAL OF DAIRY SCIENCE, 100(12), 9966–9986.

author keywords: sensory analysis; flavor; fluid milk
MeSH headings : Animals; Food Analysis / history; Food Analysis / methods; Food Quality; History, 20th Century; History, 21st Century; Humans; Milk / chemistry; Milk / history; Taste; United States
TL;DR: This review outlines the literature pertaining to relevant testing procedures and studies of the history of sensory analysis of fluid milk, and evaluation methods outside of traditional sensory techniques and future outlooks are explored and presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Short communication: Sensitive detection of norbixin in dried dairy ingredients at concentrations of less than 1 part per billion

JOURNAL OF DAIRY SCIENCE, 100(11), 8754–8758.

By: B. Carter n, C. Park n & M. Drake n

author keywords: norbixin; annatto; whey; high performance liquid chromatography
MeSH headings : Animals; Bixaceae / chemistry; Carotenoids / chemistry; Food Analysis / methods; Plant Extracts / chemistry; Sensitivity and Specificity; Solid Phase Extraction; Taste; Whey Proteins / chemistry
TL;DR: The developed method provides detection and quantification of norbixin for dairy ingredients that have a concentration of <1 ppb and had similar performance to the established method for whey proteins and permeates but was also able to detect norbIXin in powdered lactose samples. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Investigating the Effect of Growth Phase on the Surface-Layer Associated Proteome of Lactobacillus acidophilus Using Quantitative Proteomics

FRONTIERS IN MICROBIOLOGY, 8.

author keywords: Lactobacillus; probiotic; cell surface; S-layer; quantitative proteomics
TL;DR: This study establishes a framework for quantifying condition-dependent changes to cell surface proteins that can easily be applied to other S-layer forming bacteria. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Consumer Perception of Retail Pork Bacon Attributes Using Adaptive Choice-based Conjoint Analysis and Maximum Differential Scaling

JOURNAL OF FOOD SCIENCE, 82(11), 2659–2668.

By: K. McLean n, D. Hanson n, S. Jervis n & M. Drake n

author keywords: bacon; conjoint analysis; consumer liking
MeSH headings : Adolescent; Adult; Animals; Commerce; Consumer Behavior / economics; Female; Flavoring Agents / analysis; Food Preferences / psychology; Humans; Male; Meat Products / analysis; Meat Products / economics; Middle Aged; Perception; Surveys and Questionnaires; Swine; Taste; Young Adult
TL;DR: A combination of these 3 approaches can provide key understandings on consumer perception of retail bacon allowing companies to optimize and maximize their development and advertising resources. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Protein-polyphenol particles for delivering structural and health functionality

FOOD HYDROCOLLOIDS, 72, 163–173.

By: E. Foegeding n, N. Plundrich n, M. Schneider n, C. Campbell n & M. Lila n

author keywords: Protein; Polyphenols; Colloidal aggregates; Health, and Structural Functionality
TL;DR: The overall goal should be a rational design of protein-polyphenol particles to ensure a positive contribution to food quality, protein nutrition, and delivery of a health-relevant dose of polyphenols to the gastrointestinal tract. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Drivers of choice for fluid milk versus plant-based alternatives: What are consumer perceptions of fluid milk?

Journal of Dairy Science, 100(8), 6125–6138.

By: K. McCarthy n, M. Parker n, A. Ameerally n, S. Drake n & M. Drake n

MeSH headings : Animals; Beverages; Choice Behavior; Consumer Behavior; Food Preferences; Humans; Milk; Perception; Taste
TL;DR: The dairy industry should focus on the nutrition value of milk and educating consumers about misconceptions regarding dairy milk, and future beverage innovation should include the development of lactose-free milk that is also appealing to consumers in flavor. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

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