Works Published in 2015

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Displaying works 1 - 20 of 45 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Effect of cook method on consumer perception of bacon

Meat Science, 101, 106–107.

By: T. Tennant n, M. Drake n & D. Hanson n

Source: Crossref
Added: February 24, 2020

2015 journal article

An updated evolutionary classification of CRISPR–Cas systems

Nature Reviews Microbiology, 13(11), 722–736.

MeSH headings : Archaea / genetics; Bacteria / genetics; CRISPR-Cas Systems / genetics; Evolution, Molecular; Genome, Archaeal; Genome, Bacterial; Phylogeny
TL;DR: An approach combining the analysis of signature protein families and features of the architecture of cas loci that unambiguously partitions most CRISPR–cas loci into distinct classes, types and subtypes is presented. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: January 2, 2020

2015 journal article

Conserved S-Layer-Associated Proteins Revealed by Exoproteomic Survey of S-Layer-Forming Lactobacilli

Applied and Environmental Microbiology, 82(1), 134–145.

By: B. Johnson n, J. Hymes n, R. Sanozky-Dawes n, E. Henriksen n, R. Barrangou n & T. Klaenhammer n

Ed(s): H. Nojiri

MeSH headings : Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Lactobacillus / chemistry; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / metabolism; Lactobacillus acidophilus / chemistry; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / genetics; Membrane Glycoproteins / metabolism; Molecular Sequence Data; Phylogeny; Proteomics
TL;DR: Proteomic complexity and differences in the cell surface properties between S-layer- and non-S- layer-forming lactobacilli reveal the potential for SLAPs to mediate intimate probiotic interactions and signaling with the host intestinal mucosa. (via Semantic Scholar)
Source: ORCID
Added: January 2, 2020

2015 journal article

Metagenomic reconstructions of bacterial CRISPR loci constrain population histories

The ISME Journal, 10(4), 858–870.

MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / virology; Bacteriophages / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Metagenomics; Plasmids
TL;DR: Metagenomics is used to study the stability and dynamics of the type I-E CRISPR-Cas locus of Leptospirillum group II bacteria in biofilms sampled over 5 years from an acid mine drainage (AMD) system and suggest long-term coexistence of Leptonospirillo group II with AMDV1 and periods whenAMDV1 was less dominant. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries
Added: January 2, 2020

2015 journal article

CRISPR-Based Technologies and the Future of Food Science

Journal of Food Science, 80(11), R2367–R2372.

author keywords: CRISPR; genome; microbiology
MeSH headings : Bacteria / genetics; Bacteria / virology; Bacteriophages; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Fermentation; Food Technology; Humans; Probiotics
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: January 2, 2020

2015 journal article

Diversity of CRISPR-Cas immune systems and molecular machines

Genome Biology, 16(1).

By: R. Barrangou n

MeSH headings : Adaptive Immunity / genetics; Animals; Bacteria / genetics; Bacteria / immunology; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / immunology; DNA / genetics; Genetic Engineering / methods; Genetic Variation / genetics; Genetic Variation / immunology; Humans; RNA Editing / genetics
TL;DR: A plethora of CRISPR molecular machines occur broadly in prokaryotic genomes, with a diversity of Cas nucleases that can be repurposed for various applications. (via Semantic Scholar)
Source: ORCID
Added: January 2, 2020

2015 journal article

Food Protein Functionality-A New Model

JOURNAL OF FOOD SCIENCE, 80(12), C2670–C2677.

By: E. Foegeding n

author keywords: foam; gel; protein; protein functionality; sol
MeSH headings : Allergens; Diet; Dietary Proteins / chemistry; Digestion; Emulsions; Food Hypersensitivity / etiology; Functional Food; Gels; Humans; Models, Chemical; Molecular Structure; Nutritive Value; Taste
TL;DR: A new model is proposed that addresses the function of proteins in foods based on the length scale(s) responsible for the function, and emphasis should be on a common means for structure formation to allow for comparisons across investigations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 review

The Bacterial Origins of the CRISPR Genome-Editing Revolution

[Review of ]. HUMAN GENE THERAPY, 26(7), 413–424.

MeSH headings : Animals; Archaea / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Genetic Engineering / economics; Genetic Engineering / trends; Genome, Bacterial; Humans
TL;DR: The biological and mechanistic basis for these remarkable immune systems, and how their engineered derivatives are revolutionizing basic and clinical research are described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Mucosal Immunogenicity of Genetically Modified Lactobacillus acidophilus Expressing an HIV-1 Epitope within the Surface Layer Protein

PLOS ONE, 10(10).

MeSH headings : Adaptive Immunity; Animals; Antibodies, Bacterial / immunology; Antibody Formation / immunology; Antibody Specificity / immunology; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Cytokines / metabolism; Epitopes / genetics; Epitopes / immunology; HIV-1 / genetics; HIV-1 / immunology; Humans; Immunity, Mucosal; Immunization; Immunoglobulin A / immunology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / immunology; Mice; Models, Animal; Mucous Membrane / immunology; Mucous Membrane / microbiology; Mucous Membrane / virology; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / immunology
TL;DR: The constructed genetically modified Lactobacillus acidophilus strains expressing the membrane proximal external region (MPER) from human immunodeficiency virus type 1 (HIV-1) within the context of the major S-layer protein, SlpA, demonstrated the potential use of the LactOBacillus S- layer protein for development of oral vaccines targeting specific peptides. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 review

Diversity of CRISPR-Cas immune systems and molecular machines

[Review of ]. Genome Biology, 16.

By: R. Barrangou

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Sensory and Functionality Differences of Whey Protein Isolate Bleached by Hydrogen or Benzoyl Peroxide

JOURNAL OF FOOD SCIENCE, 80(10), C2153–C2160.

By: T. Smith n, E. Foegeding n & M. Drake n

author keywords: bleaching; functionality; sensory; whey protein isolate
MeSH headings : Benzoyl Peroxide / pharmacology; Bixaceae; Bleaching Agents / pharmacology; Carotenoids; Cheese; Color; Electrophoresis, Polyacrylamide Gel; Food Coloring Agents / chemistry; Functional Food / analysis; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen; Hydrogen Peroxide / pharmacology; Lipid Peroxidation; Odorants; Plant Extracts; Proteolysis / drug effects; Sulfur / analysis; Taste; Volatile Organic Compounds / analysis; Whey; Whey Proteins / chemistry; Whey Proteins / isolation & purification
TL;DR: It is demonstrated that bleaching has flavor effects as well as effects on many of the functionality characteristics of whey proteins, and provides insights for the product applications which may benefit from bleaching. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Occurrence and activity of a type II CRISPR-Cas system in Lactobacillus gasseri

MICROBIOLOGY-SGM, 161, 1752–1761.

MeSH headings : Base Sequence; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Order; Genome, Bacterial; Lactobacillus / genetics; Molecular Sequence Data; Plasmids / genetics
TL;DR: The distribution and function of a native type II-A CRISPR-Cas system in the commensal species L. gasseri is reported, which open avenues for applications for bacteriophage protection and genome modification in L.gasseri, and contribute to the fundamental understanding of CRISpr-Cas systems in bacteria. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera

NATURE COMMUNICATIONS, 6.

By: Z. Sun*, H. Harris*, A. McCann*, C. Guo*, S. Argimon*, W. Zhang*, X. Yang*, I. Jeffery* ...

MeSH headings : Biotechnology; Genome, Bacterial; Lactobacillus / enzymology; Lactobacillus / genetics; Leuconostoc / genetics; Pediococcus / genetics; Phylogeny; Sequence Analysis, DNA
TL;DR: The genome sequences of 213 different Lactobacilli strains and associated genera are reported, and new insight is provided into phylogenomic organization and adaptive immunity elements in this bacteria family, presenting a robust phylogenomic framework of existing species and for classifying new species. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Effect of temperature and concentration on benzoyl peroxide bleaching efficacy and benzoic acid levels in whey protein concentrate

JOURNAL OF DAIRY SCIENCE, 98(11), 7614–7627.

author keywords: benzoyl peroxide; benzoic acid; whey protein concentrate; bleaching
MeSH headings : Adult; Benzoic Acid / analysis; Benzoyl Peroxide / analysis; Bleaching Agents / analysis; Carotenoids / chemistry; Color; Female; Humans; Male; Middle Aged; Taste; Temperature; Whey Proteins / chemistry; Young Adult
TL;DR: It is suggested that new, soluble (liquid) BP can be used at lower concentrations than insoluble BP to achieve equivalent bleaching and that less residual benzoic acid remains in WPC80 powder from liquid whey bleached hot (50°C) than cold (4°C), which may provide opportunities to reduce benzoIC acid residues in dried whey ingredients, expanding their marketability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 review

An updated evolutionary classification of CRISPR-Cas systems

[Review of ]. Nature Reviews. Microbiology, 13(11), 722–736.

By: K. Makarova, Y. Wolf, O. Alkhnbashi, F. Costa, S. Shah, S. Saunders, R. Barrangou, S. Brouns ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

The effect of microfiltration on color, flavor, and functionality of 80% whey protein concentrate

Journal of Dairy Science, 98(9), 5862–5873.

MeSH headings : Benzoyl Peroxide / chemistry; Bleaching Agents / chemistry; Carotenoids / chemistry; Cheese; Color; Food Handling; Hydrogen Peroxide / chemistry; Lactoperoxidase / metabolism; Pasteurization; Taste; Volatile Organic Compounds / analysis; Whey / chemistry; Whey Proteins
TL;DR: Based on bleaching efficacy comparable to chemical bleaching with HP, flavor, and functionality results, MF is a viable alternative to chemical or enzymatic bleaching of fluid whey. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

JFS Special Issue: 75 years of advancing food science, and preparing for the next 75 CRISPR-based technologies and the future of food science

Journal of Food Science, 80(11), R2367–2372.

Source: NC State University Libraries
Added: August 6, 2018

2015 article

Transforming Structural Breakdown into Sensory Perception of Texture

Foegeding, E. A., Vinyard, C. J., Essick, G., Guest, S., & Campbell, C. (2015, June). JOURNAL OF TEXTURE STUDIES, Vol. 46, pp. 152–170.

By: E. Foegeding n, C. Vinyard*, G. Essick*, S. Guest* & C. Campbell n

author keywords: Food structure; mechanoreceptors; oral processing; sensory analysis; texture
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 article

Sortase-deficient lactobacilli: effect on immunomodulation and gut retention

Call, E. K., Goh, Y. J., Selle, K., Klaenhammer, T. R., & O'Flaherty, S. (2015, February). MICROBIOLOGY-SGM, Vol. 161, pp. 311–321.

By: E. Call n, Y. Goh n, K. Selle n, T. Klaenhammer n & S. O'Flaherty n

MeSH headings : Aminoacyltransferases / genetics; Aminoacyltransferases / immunology; Aminoacyltransferases / metabolism; Animals; Bacterial Adhesion; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Bacterial Proteins / metabolism; Caco-2 Cells; Cysteine Endopeptidases / genetics; Cysteine Endopeptidases / immunology; Cysteine Endopeptidases / metabolism; Dendritic Cells / immunology; Dendritic Cells / microbiology; Gastrointestinal Tract / immunology; Gastrointestinal Tract / microbiology; Humans; Immunomodulation; Lactobacillus / enzymology; Lactobacillus / genetics; Lactobacillus / growth & development; Lactobacillus / physiology; Lactobacillus acidophilus / enzymology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / physiology; Mice; Swine; Tumor Necrosis Factor-alpha / immunology
TL;DR: It is shown for the first time that sortase-dependent proteins contribute to gut retention of probiotic microbes in the gastrointestinal tract. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Sensory Perception, Nutritional Role, and Challenges of Flavored Milk for Children and Adults

JOURNAL OF FOOD SCIENCE, 80(4), R665–R670.

By: X. Li n & M. Drake n

author keywords: children; flavored milk; milk consumption; sugar content; sweeteners
MeSH headings : Adult; Animals; Child; Diet; Dietary Sucrose / administration & dosage; Feeding Behavior; Flavoring Agents / administration & dosage; Humans; Milk; Nutritive Value; Taste
TL;DR: Understanding the sensory perception of both adults and children for flavored milk can help food developers and manufacturers to address attractive attributes while reducing the sugar content to meet the needs of a healthy diet. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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