Works Published in 2012
Displaying works 601 - 620 of 691 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Longitudinal study comparing the dynamics of Clostridium difficile in conventional and antimicrobial free pigs at farm and slaughter
VETERINARY MICROBIOLOGY, 157(1-2), 172–178.
author keywords: Clostridium difficile; Antimicrobial resistance; Swine; Toxinotyping; Toxins; Farm; Slaughter
MeSH headings : Animal Husbandry / methods; Animals; Anti-Bacterial Agents / administration & dosage; Clostridioides difficile / classification; Clostridioides difficile / drug effects; Clostridioides difficile / isolation & purification; Drug Resistance, Multiple, Bacterial; Longitudinal Studies; Microbial Sensitivity Tests; Prevalence; Sus scrofa / microbiology; Swine / microbiology; Swine Diseases / microbiology
TL;DR:
It is concluded that the unique production practices employed in conventional and ABF production systems have no impact on the pathogen population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Longitudinal Study of the Persistence of Antimicrobial-Resistant Campylobacter Strains in Distinct Swine Production Systems on Farms, at Slaughter, and in the Environment
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(8), 2698–2705.
MeSH headings : Animal Husbandry; Animal Structures / microbiology; Animals; Anti-Bacterial Agents / pharmacology; Campylobacter coli / drug effects; Campylobacter coli / isolation & purification; Campylobacter jejuni / drug effects; Campylobacter jejuni / isolation & purification; Drug Resistance, Bacterial; Environmental Microbiology; Feces / microbiology; Longitudinal Studies; Microbial Sensitivity Tests; Swine / microbiology
TL;DR:
The results highlight the persistence and dissemination of AR Campylobacter from farm to slaughter in ABF and conventionally raised pigs and their environments.
(via Semantic Scholar)
aem.asm.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Live-Cell Fluorescence Microscopy with Molecular Biosensors: What Are We Really Measuring?
BIOPHYSICAL JOURNAL, 102(9), 2003–2011.
MeSH headings : Animals; Humans; Microscopy, Fluorescence / methods; Molecular Imaging / methods; Molecular Probe Techniques; Molecular Probes / metabolism; Protein Interaction Mapping / methods
TL;DR:
To address the pitfalls of the biosensor approach in quantitative terms, simple reaction-diffusion models were analyzed and a sobering insight emerges: the observer or saturation effect is always significant; the question is whether or not it can be tolerated or accounted for.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
LACK OF HYDROXYLATED FULLERENE TOXICITY AFTER INTRAVENOUS ADMINISTRATION TO FEMALE SPRAGUE-DAWLEY RATS
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 75(7), 367–373.
MeSH headings : Animals; Blood Chemical Analysis; Drug Administration Schedule; Female; Fullerenes / administration & dosage; Fullerenes / chemistry; Fullerenes / toxicity; Injections, Intravenous; Liver / drug effects; Lymphocytes / drug effects; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Nanoparticles / toxicity; Rats; Rats, Sprague-Dawley; Thymus Gland / drug effects; Toxicity Tests, Acute; Urinalysis
TL;DR:
These experiments suggest that this fullerol was well tolerated after iv administration to rats, and no clinically significant chemistry changes were observed after treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 article
Infertility in the Southern White Rhino: Is Diet the Source of the Problem?
Patisaul, H. B. (2012, April). ENDOCRINOLOGY, Vol. 153, pp. 1568–1571.
MeSH headings : Animals; Coumestrol / pharmacology; Female; Humans; Isoflavones / pharmacology; Receptors, Estrogen / metabolism
TL;DR:
Evidence is provided that the fertility of captive rhinos is being compromised, not by malnutrition but through endocrine disruption by phytoestrogens, which appears to be contributing to the reproductive impairments reported in captive born Southern White Rhinoceros.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 article
High-resolution mass spectrometry
Maurer, H. H., & Muddiman, D. C. (2012, May). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 403, pp. 1201–1202.
MeSH headings : Animals; Biological Science Disciplines; Environmental Pollutants / analysis; Food Analysis; Humans; Mass Spectrometry / instrumentation; Mass Spectrometry / methods; Substance Abuse Detection
TL;DR:
An overview of the current use of high-resolution mass spectrometry in the life sciences is given, intended for all readers with an interest in application of HRMS in clinical and forensic toxicology, doping control, drug metabolism, food analysis, environmental sciences, and proteomics and related fields.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Global models of ant diversity suggest regions where new discoveries are most likely are under disproportionate deforestation threat
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(19), 7368–7373.
Contributors: B. Gueńard n, M. Weiser n & R. Dunn n
author keywords: biogeography; Formicidae
MeSH headings : Animals; Ants / classification; Ants / growth & development; Biodiversity; Conservation of Natural Resources / methods; Ecosystem; Environmental Monitoring / methods; Geography; Models, Biological
TL;DR:
A database representing about 13,000 records for ant generic distribution from over 350 regions that cover much of the globe is assembled, finding that the hotspots of discovery are also the regions in which biodiversity is the most threatened by habitat destruction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation
JOURNAL OF EXPERIMENTAL MEDICINE, 209(6), 1105–1119.
MeSH headings : ADAM Proteins / genetics; ADAM Proteins / metabolism; ADAM17 Protein; Administration, Topical; Animals; Animals, Newborn; Cell Differentiation / physiology; Dermatitis, Atopic / pathology; Epidermal Cells; Epidermis / metabolism; Epidermis / pathology; ErbB Receptors / genetics; ErbB Receptors / metabolism; Gene Expression Regulation, Developmental; Interleukin-1 / metabolism; Keratinocytes / cytology; Keratinocytes / metabolism; Macrophages / pathology; Mice; Mice, Mutant Strains; Skin / cytology; Skin / growth & development; Skin / metabolism; Transforming Growth Factor alpha / administration & dosage; Transforming Growth Factor alpha / genetics; Transforming Growth Factor alpha / pharmacology; Transglutaminases / metabolism
TL;DR:
EGFR requires ADAM17 activity to preserve skin barrier homeostasis and needs to be tuned to prevent cell reprograming and cell death.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs
PLoS ONE, 7(2), e32072.
Contributors: T. Olivry n , K. Linder n, P. Wang *, P. Bizikova n, J. Bernstein, S. Dunston n, J. Paps n, M. Casal *
Ed(s): J. Brandner
MeSH headings : Animals; DNA Primers / genetics; Desmosomes / metabolism; Disease Models, Animal; Dogs; Ectodermal Dysplasia / genetics; Gene Expression Regulation; Keratins / chemistry; Microscopy, Electron / methods; Microscopy, Electron, Transmission / methods; Mutation; Phenotype; Plakophilins / biosynthesis; Plakophilins / genetics; Sequence Analysis, DNA / methods; Skin / pathology; Skin Diseases / genetics; Skin Diseases / metabolism
TL;DR:
The clinical and pathological findings, along with the PKP1 mutation, were consistent with the diagnosis of ectodermal dysplasia-skin fragility syndrome with plakophilin-1 deficiency, a novel congenital acantholytic dermatosis that developed in Chesapeake Bay retriever dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2012 journal article
Behavior of Poly(epsilon-caprolactone)s (PCLs) Coalesced from Their Stoichiometric Urea Inclusion Compounds and Their Use as Nucleants for Crystallizing PCL Melts: Dependence on PCL Molecular Weights
MACROMOLECULES, 45(6), 2835–2840.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease-endemic Region
EMERGING INFECTIOUS DISEASES, 18(5), 783–791.
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Arthritis / microbiology; Bacteremia / diagnosis; Bacteremia / epidemiology; Bacteremia / microbiology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Lyme Disease / epidemiology; Male; Middle Aged; Molecular Typing; Serotyping; Surveys and Questionnaires; Young Adult
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Vector-Borne Diseases - constant challenge for practicing veterinarians: recommendations from the CVBD World Forum
Parasites & Vectors, 5(1), 55.
MeSH headings : Animals; Bacterial Infections / diagnosis; Bacterial Infections / drug therapy; Bacterial Infections / prevention & control; Bacterial Infections / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / prevention & control; Dogs; Parasitic Diseases, Animal / diagnosis; Parasitic Diseases, Animal / drug therapy; Parasitic Diseases, Animal / prevention & control; Veterinary Medicine / methods
TL;DR:
Recommendations to veterinarians for the management of canine vector-borne diseases (CVBDs), a growing global threat as they continue their spread far from their traditional geographical and temporal restraints as a result of changes in both climatic conditions and pet dog travel patterns.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2012 journal article
Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 35(2), 113–120.
MeSH headings : Adipose Tissue; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Disaccharides / administration & dosage; Disaccharides / blood; Disaccharides / pharmacokinetics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Residues; Female; Goats / metabolism; Heterocyclic Compounds / administration & dosage; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Infusions, Subcutaneous; Kidney; Liver; Lung; Male; Muscle, Skeletal; Reproducibility of Results; Tissue Distribution
TL;DR:
It is demonstrated that tissue levels in goats are very similar to those seen in swine and cattle, and below limit of quantification in injection site and lung by day 18 and in liver, kidney, muscle, and fat at all time points.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Thin-layer spectroelectrochemistry of the Fe(III)/Fe(II) redox reaction of dehaloperoxidase-hemoglobin
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 668, 37–43.
author keywords: Dehaloperoxidase; Hemoglobin; Fe(III)/Fe(II) reduction potential; Gibbs free energy analysis; Distal histidine conformation; Redox thermodynamic square scheme
TL;DR:
A thermodynamic cycle that links the conformational change to electron transfer is shown to be consistent with a positive shift in reduction potential if the open conformation is differentially favored by the Fe(II) state, a proposal that is supported by the available crystallographic data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Reproductive consequences of developmental phytoestrogen exposure
REPRODUCTION, 143(3), 247–260.
MeSH headings : Animals; Child Development / drug effects; Diet; Humans; Infant; Infant Food / adverse effects; Infant Formula / chemistry; Infant, Newborn; Phytoestrogens / adverse effects; Phytoestrogens / pharmacology; Reproduction / drug effects; Reproduction / physiology
TL;DR:
The aim of this review is to examine the evidence that phytoestrogen exposure, particularly in the developmentally sensitive periods of life, has consequences for future reproductive health.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2012 journal article
Renal Disease in Cats Infected with Feline Immunodeficiency Virus
JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(2), 238–243.
author keywords: Azotemia; Glomerulonephropathy; Human immunodeficiency virus - associated nephropathy; Proteinuria
MeSH headings : Animals; Blood Urea Nitrogen; CD4-CD8 Ratio / veterinary; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / virology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / virology; Cats; Creatinine / blood; Cross-Sectional Studies; Feline Acquired Immunodeficiency Syndrome / blood; Feline Acquired Immunodeficiency Syndrome / complications; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Female; Immunodeficiency Virus, Feline / isolation & purification; Kidney Diseases / blood; Kidney Diseases / immunology; Kidney Diseases / veterinary; Kidney Diseases / virology; Male; Prospective Studies; Proteinuria / veterinary; Retrospective Studies; Specific Pathogen-Free Organisms; Statistics, Nonparametric
TL;DR:
Proteinuria but not azotemia was associated with natural FIV infection and neither neuter status nor health status were risk factors for proteinuria in FIV-infected cats, but UPC was positively correlated with the CD4+:CD8+ T lymphocyte ratio.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Production of prostaglandin E-2 in response to infection with modified vaccinia Ankara virus
VIROLOGY, 428(2), 146–155.
author keywords: Poxvirus; Vaccine; Lipid mediator; Cyclooxygenase-2; Cytosolic phospholipase A(2); NF-kappa B
MeSH headings : Animals; Arachidonic Acid / metabolism; Cell Line; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Dinoprostone / metabolism; Humans; Mice; Vaccinia / enzymology; Vaccinia / metabolism; Vaccinia / virology; Vaccinia virus / genetics; Vaccinia virus / physiology; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR:
In this study, PGE₂ production in vitro by cells infected with the poxvirus vaccine strain, modified vaccinia Ankara virus (MVA), is investigated and it is demonstrated that MVA induced the release of AA from infected cells, and this was, most unusually, independent of host cytosolic phospholipase A₁ activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Porphyrin-Cellulose Nanocrystals: A Photobactericidal Material that Exhibits Broad Spectrum Antimicrobial Activity†
Photochemistry and Photobiology, 88(3), 527–536.
Contributors: B. Carpenter n, E. Feese n, H. Sadeghifar n, D. Argyropoulos n & R. Ghiladi n
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / pharmacology; Cellulose / chemistry; Drug Resistance, Microbial; Microscopy, Confocal; Microscopy, Fluorescence; Nanoparticles; Photochemotherapy; Porphyrins / chemistry; Spectrophotometry, Ultraviolet; Staphylococcus aureus / drug effects
TL;DR:
Research into alternative materials such as CNC‐Por may lead to their application in hospitals and healthcare‐related industries wherein novel materials with the capability of reducing the rates of transmission of a wide range of bacteria, particularly antibiotic resistant strains, are desired.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2012 article
Polymers coalesced from their cyclodextrin inclusion complexes: What can they tell us about the morphology of melt-crystallized polymers?
Gurarslan, A., Joijode, A. S., & Tonelli, A. E. (2012, June 15). JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, Vol. 50, pp. 813–823.
author keywords: cyclodextrin; inclusion chemistry; morphology; solid-state structure; thermal stability
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Joint genotyping on the fly: Identifying variation among a sequenced panel of inbred lines
GENOME RESEARCH, 22(5), 966–974.
MeSH headings : Algorithms; Animals; Chromosome Mapping; Computer Simulation; Drosophila melanogaster / genetics; Genetic Variation; Genotyping Techniques / standards; Inbreeding; Likelihood Functions; Models, Genetic; Polymorphism, Single Nucleotide; Reference Standards; Sequence Analysis, DNA
TL;DR:
This work presents the Joint Genotyper for Inbred Lines (JGIL) as a method for obtaining genotypes and identifying variation among a large panel of inbred strains or lines, and illustrates how JGIL is robust to moderate levels of error.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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