Works (23)

Updated: April 11th, 2023 10:13

2021 journal article

Preliminary results of neutron and X-ray diffraction data collection on a lytic polysaccharide monooxygenase under reduced and acidic conditions

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 77(4), 128–133.

By: G. Schroder, . William B. O'Dell n, P. Swartz & F. Meilleur

author keywords: lytic polysaccharide monooxygenases; Neurospora crassa; neutron protein crystallography; reduction; protonation; enzymatic mechanism.
Sources: Web Of Science, ORCID
Added: April 1, 2021

2021 journal article

Remodeling hydrogen bond Interactions results in relaxed specificity of Caspase-3

BIOSCIENCE REPORTS, 41(1).

By: L. Yao*, P. Swartz, P. Hamilton & A. Clark*

Sources: Web Of Science, ORCID
Added: April 12, 2021

2020 journal article

Caspases from scleractinian coral show unique regulatory features

JOURNAL OF BIOLOGICAL CHEMISTRY, 295(43), 14578–14591.

By: S. Shrestha*, J. Tung*, R. Grinshpon n, P. Swartz, P. Hamilton, B. Dimos*, L. Mydlarz*, A. Clark

author keywords: caspase; cysteine protease; allosteric regulation; substrate specificity; coral apoptosis; coral immunity; functional divergence; substrate selection; CARD-caspase; apoptosis
Sources: Web Of Science, ORCID
Added: January 14, 2021

2020 journal article

DRoP: Automated detection of conserved solvent-binding sites on proteins

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 88(1), 152–165.

By: B. Kearney n, M. Schwabe*, K. Marcus*, D. Roberts n, M. Dechene, P. Swartz, C. Mattos

author keywords: conserved solvent positions; DRoP software; protein hydration; protein multiple crystal structures; RNase A; water analysis program
Source: Web Of Science
Added: August 12, 2019

2020 journal article

Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 76, 1001–1014.

By: S. Agarwal, M. Smith, I. De La Rosa, K. Verba, P. Swartz, M. Segura-Totten, C. Mattos

author keywords: BAF; multiple solvent crystal structures; conserved water for structure refinement; differentialB-factor analysis
Source: Web Of Science
Added: November 16, 2020

2018 journal article

Modifications to a common phosphorylation network provide individualized control in caspases

JOURNAL OF BIOLOGICAL CHEMISTRY, 293(15), 5447–5461.

By: M. Thomas, R. Grinshpon n, P. Swartz & A. Clark*

Source: Web Of Science
Added: August 6, 2018

2018 journal article

Selective tuning of activity in a multifunctional enzyme as revealed in the F21W mutant of dehaloperoxidase B from Amphitrite ornata

JBIC Journal of Biological Inorganic Chemistry, 23(2), 209–219.

By: L. Carey n, K. Kim n, N. McCombs n, P. Swartz, C. Kim* & R. Ghiladi

author keywords: Globin; Peroxidase; Peroxygenase; Structure-function relationship
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 73(2), 70–78.

By: . William B. O'Dell n, P. Swartz, K. Weiss* & F. Meilleur

author keywords: lytic polysaccharide monooxygenases; Pichia pastoris; glycoengineering; neutron proteincrystallography
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish

Protein Science, 25(11), 2076–2088.

By: M. Tucker n, S. MacKenzie n, J. Maciag n, H. Dirscherl Ackerman, P. Swartz, J. Yoder, P. Hamilton, A. Clay Clark

author keywords: phage display substrate library; substrate recognition; Danio rerio; apoptosis
Sources: Crossref, ORCID
Added: January 31, 2019

2016 journal article

Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(41), E6080–E6088.

By: J. Maciag, S. Mackenzie, M. Tucker n, J. Schipper, P. Swartz & A. Clark

author keywords: allostery; conformational selection; saturation mutagenesis; protein solvation; protein structure
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 70(Pt 6), 773–776.

By: A. Bodenheimer, M. Cuneo*, P. Swartz, J. He*, H. O'Neill*, D. Myles*, B. Evans*, F. Meilleur, F. Section

Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

DRoP: A Water Analysis Program Identifies Ras-GTP-Specific Pathway of Communication between Membrane-Interacting Regions and the Active Site

JOURNAL OF MOLECULAR BIOLOGY, 426(3), 611–629.

By: B. Kearney n, C. Johnson*, D. Roberts n, P. Swartz & C. Mattos

author keywords: crystallographic water analysis; Ras GTPase; water-mediated networks in protein structure; protein hydration; DRoP software
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Modifying Caspase-3 Activity by Altering Allosteric Networks

BIOCHEMISTRY, 53(48), 7582–7595.

By: C. Cade, P. Swartz, S. MacKenzie & A. Clark

Source: Web Of Science
Added: August 6, 2018

2013 journal article

Lengthening the Intersubunit Linker of Procaspase 3 Leads to Constitutive Activation

BIOCHEMISTRY, 52(36), 6219–6231.

Source: Web Of Science
Added: August 6, 2018

2013 journal article

The role of T56 in controlling the flexibility of the distal histidine in dehaloperoxidase-hemoglobin from Amphitrite ornata

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1834(10), 2020–2029.

By: S. Jiang, I. Wright, P. Swartz & S. Franzen

author keywords: Enzyme kinetics; Catalytic efficiency; Hemichrome; Resonance Raman; Molecular dynamics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Allosteric modulation of caspase 3 through mutagenesis

BIOSCIENCE REPORTS, 32(4), 401–411.

author keywords: allosteric site; apoptosis; caspase; inhibition; protein ensemble
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 508(1), 31–38.

By: J. Walters, P. Swartz, C. Mattos & A. Clark

author keywords: Apoptosis; Caspase activation; Enzyme activity; Protein folding and assembly
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 66(Pt 11), 1458–1462.

By: S. Martin, R. Guenther n, T. Sit, P. Swartz, F. Meilleur, S. Lommel, R. Rose, F. Section

author keywords: red clover necrotic mosaic virus; dianthoviruses; viruses
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis

BIOCHEMICAL JOURNAL, 424, 335–345.

By: J. Walters, C. Pop*, F. Scott*, M. Drag*, P. Swartz, C. Mattos, G. Salvesen*, A. Clark

author keywords: apoptosis; cancer therapy; conformational switch; co-operative dimer interface; procaspase activation
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Multiple solvent crystal structures of ribonuclease A: An assessment of the method

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 76(4), 861–881.

By: M. Dechene, G. Wink, M. Smith, P. Swartz & C. Mattos

author keywords: organic solvents; solvent mapping; plasticity; hydration; protein binding sites
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Role of loop bundle hydrogen bonds in the maturation and activity of (pro) caspase-3

BIOCHEMISTRY, 45(44), 13249–13263.

By: B. Feeney, C. Pop n, P. Swartz, C. Mattos & A. Clark

Source: Web Of Science
Added: August 6, 2018

2004 journal article

Comparative mutagenicity of halomethanes and halonitromethanes in Salmonella TA100: structure–activity analysis and mutation spectra

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 554(1-2), 335–350.

By: B. Kundu*, S. Richardson*, C. Granville*, D. Shaughnessy*, N. Hanley*, P. Swartz, A. Richard*, D. DeMarini*

author keywords: halonitromethanes; halomethanes; mutagenicity; Salmonella; drinking water; mutation spectra
Source: Crossref
Added: August 28, 2020

2004 journal article

Mutagenicity in Salmonella of halonitromethanes: a recently recognized class of disinfection by-products in drinking water

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 562(1-2), 39–65.

By: B. Kundu*, S. Richardson*, P. Swartz, P. Matthews*, A. Richard* & D. DeMarini*

Source: Crossref
Added: August 28, 2020