Works Published in 2005

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Displaying works 101 - 120 of 133 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2005 journal article

Solving the protein sequence metric problem

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(18), 6395–6400.

By: W. Atchley n, J. Zhao n, A. Fernandes n & T. Druke n

author keywords: basic helix-loop-helix; molecular evolution; multivariate statistics; amino acid attributes; factor analysis
MeSH headings : Amino Acid Sequence / genetics; Analysis of Variance; Cluster Analysis; Codon / genetics; Computational Biology / methods; Discriminant Analysis; Genetic Variation; Models, Genetic; Multivariate Analysis; Phylogeny; Protein Conformation; Static Electricity; Statistics as Topic / methods
TL;DR: Multivariate statistical analyses on almost 500 amino acid attributes are used to produce a small set of highly interpretable numeric patterns of amino acid variability that reflect polarity, secondary structure, molecular volume, codon diversity, and electrostatic charge. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Sequence signatures and the probabilistic identification of proteins in the Myc-Max-Mad network

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(18), 6401–6406.

author keywords: Myc; predictive motif; transcription factor; oncoprotein; molecular evolution
MeSH headings : Amino Acid Sequence / genetics; Basic-Leucine Zipper Transcription Factors; Computational Biology / methods; DNA-Binding Proteins / genetics; Fuzzy Logic; Genetic Variation; Genomics / methods; Helix-Loop-Helix Motifs / genetics; Molecular Sequence Data; Protein Conformation; Proto-Oncogene Proteins c-myc / genetics; Repressor Proteins / genetics; Sequence Alignment; Sequence Homology; Transcription Factors / genetics
TL;DR: A small set of amino acid sites from the N-terminal portion of the basic helix-loop-helix (bHLH) domain are described that provide very accurate sequence signatures for the Myc-Max-Mad transcription factor network and three of its member proteins. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Reinnervation of the rat levator ani muscle after neonatal denervation

JOURNAL OF NEUROBIOLOGY, 63(3), 188–198.

By: J. Lubischer*, G. Unguez*, D. Pierotti*, R. Roy* & V. Edgerton*

author keywords: axotomy; motoneuronal death; denervation; motor unit; fatigability; maximum tetanic tension; development
MeSH headings : Age Factors; Animals; Animals, Newborn / physiology; Axotomy / methods; Male; Motor Neurons / physiology; Muscle Contraction / physiology; Muscle Denervation / methods; Muscle, Skeletal / innervation; Muscle, Skeletal / physiology; Rats; Rats, Sprague-Dawley
TL;DR: The data suggest that motoneurons that survived injury on postnatal day 14 innervated more muscle fibers than normal and exhibited a similar ability to functionally reinnervate the target muscle as those motoneURons that survive injury on P21. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 journal article

Modeling quantitative trait loci and interpretation of models

GENETICS, 169(3), 1711–1725.

MeSH headings : Gene Frequency; Linkage Disequilibrium; Models, Genetic; Models, Statistical; Quantitative Trait Loci; Regression Analysis
TL;DR: A quantitative genetic model relates the genotypic value of an individual to the alleles at the loci that contribute to the variation in a population in terms of additive, dominance, and epistatic effects and proposes a number of models to describe this relationship. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Mark-recapture estimators for dual frame population size of prominent nesting structures: the effect of uncertain detection probability

ENVIRONMENTAL AND ECOLOGICAL STATISTICS, 12(2), 155–168.

By: R. Alpizar-Jara*, K. Pollock n & D. Haines*

author keywords: area sampling; eagle nests; Lincoln-Petersen method; line transect sampling; screening estimator; wildlife population estimation
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 article

Involvement of phospholipase C and intracellular calcium signaling in the gonadotropin-releasing hormone regulation of prolactin release from lactotrophs of tilapia (Oreochromis mossambicus)

Tipsmark, C. K., Weber, G. M., Strom, C. N., Grau, E. G., Hirano, T., & Borski, R. J. (2005, May 15). GENERAL AND COMPARATIVE ENDOCRINOLOGY, Vol. 142, pp. 227–233.

By: C. Tipsmark n, G. Weber*, C. Strom n, E. Grau*, T. Hirano* & R. Borski n

author keywords: GnRH; calcium signaling; prolactin; tilapia; lactotrophs
MeSH headings : Animals; Calcium / metabolism; Calcium Signaling / physiology; Estrenes / pharmacology; Gallic Acid / analogs & derivatives; Gallic Acid / pharmacology; Gonadotropin-Releasing Hormone / physiology; Inositol 1,4,5-Trisphosphate / metabolism; Male; Pituitary Gland / cytology; Pituitary Gland / drug effects; Pituitary Gland / metabolism; Platelet Aggregation Inhibitors / pharmacology; Prolactin / metabolism; Pyrrolidinones / pharmacology; Tilapia / metabolism; Type C Phospholipases / antagonists & inhibitors; Type C Phospholipases / physiology
TL;DR: Findings suggest that GnRH may elicit its PRL releasing effect by increasing Ca(i)2+, which may be derived from PLC/IP3-induced mobilization of Ca2+ from intracellular stores along with influx through L-type voltage-gated Ca 2+ channels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Genetic architecture of transcript-level variation in differentiating xylem of a eucalyptus hybrid

GENETICS, 169(4), 2295–2303.

MeSH headings : Cell Differentiation; Chimera; Chromosome Mapping; Crosses, Genetic; Eucalyptus / genetics; Gene Expression Regulation; Genes, Plant; Genetic Linkage; Genetic Markers; Genetic Variation; Genome, Plant; Genotype; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Phylogeny; Quantitative Trait Loci; RNA, Messenger / metabolism
TL;DR: To analyze and compare the genetic architecture of transcript regulation in different genetic backgrounds of Eucalyptus, microarrays were used to examine variation in mRNA abundance in the differentiating xylem of a E. grandis pseudobackcross population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

The anti-apoptotic effects of nordihydroguaiaretic acid: Inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling

LIFE SCIENCES, 77(19), 2457–2470.

author keywords: apoptosis; NDGA; cPLA(2)
MeSH headings : Animals; Antioxidants / pharmacology; Apoptosis / drug effects; Arachidonic Acid / metabolism; Blotting, Western; Butylated Hydroxyanisole / pharmacology; Calcium Signaling / drug effects; Caspases / metabolism; Cell Line; Chromium Radioisotopes; Enzyme Activation / drug effects; Fibroblasts / drug effects; Fibroblasts / metabolism; Immunoprecipitation; Male; Masoprocol / pharmacology; Mice; Microscopy, Phase-Contrast; Phosphates / metabolism; Phospholipases A / antagonists & inhibitors; Tumor Necrosis Factor-alpha / pharmacology
TL;DR: The mechanism underlying the ability of NDGA to inhibit TNF-induced apoptosis is examined and it is shown that NDGA blocks many key indicators of apoptosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Polygenic mutation in Drosophila melanogaster: Mapping spontaneous mutations affecting sensory bristle number

GENETICS, 170(4), 1723–1735.

By: T. Mackay n, R. Lyman n & F. Lawrence n

MeSH headings : Animals; Chromosome Mapping; Drosophila melanogaster / genetics; Genes, Insect; Genetic Complementation Test; Genetic Variation; Genome, Insect; Mutation; Quantitative Trait Loci; Quantitative Trait, Heritable; Selection, Genetic; X Chromosome
TL;DR: Estimates of the numbers of mutations and mutational effects were consistent with diploid per-character mutation rates for bristle traits and imply that >2% of the genome could affect just one bristle trait and that there must be extensive pleiotropy for quantitative phenotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Experimental support for an immunological approach to the search for life on other planets

ASTROBIOLOGY, 5(1), 30–47.

By: M. Schweitzer n, J. Wittmeyer n, R. Avci* & S. Pincus*

author keywords: Antibody reactivity; extraction methods; exobiology; astrobiology
MeSH headings : Biomarkers / analysis; Enzyme-Linked Immunosorbent Assay / methods; Exobiology / methods; Extraterrestrial Environment; Fossils; Immunologic Techniques; Planets
TL;DR: A three-phase approach to test for evidence of life in extraterrestrial samples capitalizes on the flexibility, sensitivity, and specificity of antibody-antigen interactions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Diminished expression of C/EBP alpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBP alpha in carcinoma cells inhibits proliferation

Cancer Research, 65(3), 861–867.

By: M. Shim, K. Powers, S. Ewing, S. Zhu & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Detection and identification of histamine-producing bacteria associated with harvesting and processing mahimahi and yellowfin tuna

JOURNAL OF FOOD PROTECTION, 68(8), 1676–1682.

By: D. Allen n, D. Green n, G. Bolton n, L. Jaykus n & W. Cope n

MeSH headings : Animals; Consumer Product Safety; Food Contamination / analysis; Food Handling / methods; Food Microbiology; Food-Processing Industry / methods; Food-Processing Industry / standards; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacteria / metabolism; Histamine / analysis; Histamine / biosynthesis; Humans; North Carolina; Perciformes / microbiology; Seafood / microbiology; Tuna / microbiology
TL;DR: It is revealed that gram-negative bacteria might not be solely responsible for histamine production in at-risk fish, and no seafood safety risks were found under the standard industry practices observed in this study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Aromatase cytochrome P450: Cloning, intron variation, and ontogeny of gene expression in southern flounder (Paralichthys lethostigma)

JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY, 303A(8), 643–656.

MeSH headings : Amino Acid Sequence; Animals; Aromatase / chemistry; Aromatase / genetics; Aromatase / metabolism; Base Sequence; Cloning, Molecular; Female; Flounder / genetics; Flounder / metabolism; Gene Expression Regulation, Developmental / physiology; Gene Expression Regulation, Enzymologic; Genetic Variation; Introns / genetics; Male; Molecular Sequence Data; Phylogeny; RNA, Messenger; Tissue Distribution
TL;DR: Gonadal histology confirmed predictions of sex based on P450arom expression in juvenile flounder, demonstrating that the patterns of P450Arom expression observed relate to sex-specific differentiation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 article

Androgen metabolism in invertebrates and its modulation by xenoandrogens - A comparative study

TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY, Vol. 1040, pp. 354–356.

By: G. Janer*, G. LeBlanc n & C. Porte*

author keywords: androgen; steroid metabolism; organotin; fenarimol; invertebrates
MeSH headings : Androgens / metabolism; Animals; Crustacea / metabolism; Echinodermata / metabolism; Mollusca / metabolism; Species Specificity; Xenobiotics / metabolism
TL;DR: The work evidenced different sensitivity of those pathways to androgenic compounds, together with interphyla differences in androgen metabolism, as well as different sensitivity and tissue‐specific distribution of those enzymatic activities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean

JOURNAL OF EXPERIMENTAL BIOLOGY, 208(1), 15–23.

author keywords: Cladocera; juvenoid; endocrine disruption; evolution; nuclear receptor; Daphnia magna
MeSH headings : Analysis of Variance; Animals; Base Sequence; DNA Primers; Daphnia / physiology; Electrophoresis; Fatty Acids, Unsaturated / pharmacology; Hemoglobins / genetics; Hemoglobins / metabolism; Male; Molecular Sequence Data; Reproduction / physiology; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sex Differentiation / drug effects; Signal Transduction / physiology; Spectrophotometry; Stress, Physiological / metabolism; Terpenes / metabolism
TL;DR: It is demonstrated that two responses to environmental stress signaling in the crustacean Daphnia magna - hemoglobin accumulation and male offspring production - are co-elevated by the crustACEan terpenoid hormone methyl farnesoate and several synthetic analogs, suggesting that both processes are regulated by the same ter penoid signaling pathway. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 review

Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses

[Review of ]. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 38(7), 995–1014.

author keywords: catalase; aging; telomeres; gene regulation; superoxide dismutase; genomics
MeSH headings : Aging / genetics; Aging / metabolism; Antioxidants / physiology; Gene Expression / physiology; Genome; Humans; Oxidative Stress / genetics; Oxidative Stress / physiology; Reactive Oxygen Species; Signal Transduction / genetics; Signal Transduction / physiology; Telomere / genetics
TL;DR: Antioxidant-specific gene induction, involved in xenobiotic metabolism, is mediated by the "ant antioxidant responsive element" (ARE) commonly found in the promoter region of such genes, but has not been found in plant Gst genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 review

Assisting Hox proteins in controlling body form: are there new lessons from flies (and mammals)?

[Review of ]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 15(4), 422–429.

By: J. Mahaffey n

MeSH headings : Amino Acid Sequence; Animals; Body Patterning / genetics; DNA-Binding Proteins / genetics; Diptera / embryology; Diptera / genetics; Gene Expression Regulation, Developmental; Homeodomain Proteins / genetics; Mice; Models, Genetic; Sequence Homology, Amino Acid; Zinc Fingers / genetics
TL;DR: There is now evidence that a global network of zinc finger transcription factors contributes to patterning of the Drosophila embryo, and it is possible that these zinc finger proteins are Hox cofactors, providing additional specificity during Hox target-gene selection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Anabaena sp strain PCC 7120 gene devH is required for synthesis of the heterocyst glycolipid layer

JOURNAL OF BACTERIOLOGY, 187(7), 2326–2331.

By: M. Ramirez n, P. Hebbar n, R. Zhou*, C. Wolk* & S. Curtis n

MeSH headings : Aerobiosis; Anabaena / genetics; Anabaena / metabolism; Anabaena / ultrastructure; Bacterial Proteins / biosynthesis; Bacterial Proteins / genetics; Gene Expression Regulation, Bacterial / physiology; Genes, Bacterial / physiology; Glycolipids / biosynthesis; Mutation; Nitrogen / physiology; Nitrogen Fixation / genetics; Nitrogen Fixation / physiology; Operon; Phenotype; Transcription Factors
TL;DR: It is demonstrated that rearrangements of nitrogen fixation genes take place normally in the devH mutant and that it is Fix(+), i.e., has nitrogenase activity under anoxic conditions. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Testosterone conjugating activities in invertebrates: are they targets for endocrine disruptors?

AQUATIC TOXICOLOGY, 71(3), 273–282.

By: G. Janer*, R. Sternberg n, G. LeBlanc n & C. Porte*

author keywords: sulfotransferase; Acyl-CoA; testosterone acyltransferase; echinoderm; Crustacea; mollusc
MeSH headings : Acyltransferases / metabolism; Analysis of Variance; Animals; Cytosol / metabolism; Invertebrates / drug effects; Invertebrates / enzymology; Italy; Kinetics; Microsomes / metabolism; Organotin Compounds / toxicity; Palmitoyl Coenzyme A / metabolism; Pyrimidines / toxicity; Seawater; Species Specificity; Sulfotransferases / metabolism; Testosterone / metabolism; Trialkyltin Compounds / toxicity; Water Pollutants, Chemical / toxicity
TL;DR: The results demonstrated the existence of interphyla differences in testosterone conjugation, and revealed that these processes can serve as targets for endocrine disrupting chemicals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Soft-tissue vessels and cellular preservation in Tyrannosaurus rex

SCIENCE, 307(5717), 1952–1955.

By: M. Schweitzer n, J. Wittmeyer n, . Horner n & J. Toporski*

MeSH headings : Animals; Blood Vessels / anatomy & histology; Blood Vessels / cytology; Bone Demineralization Technique; Bone Matrix; Bone and Bones / anatomy & histology; Bone and Bones / blood supply; Bone and Bones / cytology; Cell Separation; DNA / analysis; Dinosaurs / anatomy & histology; Elasticity; Femur / anatomy & histology; Femur / blood supply; Fossils; Microscopy, Electron, Scanning; Montana; Osteocytes / cytology; Osteocytes / ultrastructure; Time
TL;DR: Soft tissues are preserved within hindlimb elements of Tyrannosaurus rex and removal of the mineral phase reveals transparent, flexible, hollow blood vessels containing small round microstructures that can be expressed from the vessels into solution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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