Works Published in 2019
Displaying works 121 - 140 of 212 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
The Status of Forensic Anthropology in Europe and South Africa: Results of the 2016 FASE Questionnaire on Forensic Anthropology
JOURNAL OF FORENSIC SCIENCES, 64(4), 1017–1025.
author keywords: forensic science; forensic anthropology; survey; education; practice; identification
MeSH headings : Age Determination by Skeleton; Biometric Identification; Employment; Europe; Forensic Anthropology / education; Forensic Anthropology / organization & administration; Humans; Societies, Scientific; South Africa; Surveys and Questionnaires
TL;DR:
An online questionnaire was sent to European and South African practitioners of forensic anthropology and related disciplines in 2016 showed that the status and roles of forensic anthropologists vary depending on the national legal systems, education, and employment status of the practitioners.
(via Semantic Scholar)
Source: Web Of Science
Added: July 22, 2019
2019 journal article
Coordinating Tissue Regeneration Through Transforming Growth Factor-beta Activated Kinase 1 Inactivation and Reactivation
STEM CELLS, 37(6), 766–778.
author keywords: Cellular proliferation; Differentiation; Progenitor cells; Proliferation; Stem; progenitor cell; Tissue regeneration
MeSH headings : Animals; Bone Regeneration / drug effects; Bone Regeneration / genetics; Cell Differentiation / drug effects; Cell Proliferation / drug effects; DNA Nucleotidyltransferases / genetics; DNA Nucleotidyltransferases / metabolism; Female; Founder Effect; Fractures, Bone / drug therapy; Fractures, Bone / enzymology; Fractures, Bone / genetics; Fractures, Bone / pathology; Gene Expression Regulation; Integrases / genetics; Integrases / metabolism; MAP Kinase Kinase Kinases / antagonists & inhibitors; MAP Kinase Kinase Kinases / deficiency; MAP Kinase Kinase Kinases / genetics; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / enzymology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Osteoblasts / cytology; Osteoblasts / drug effects; Osteoblasts / enzymology; Primary Cell Culture; Protein Kinase Inhibitors / pharmacology; Signal Transduction; Skull / drug effects; Skull / injuries; Skull / metabolism; Wound Healing / drug effects; Wound Healing / genetics
TL;DR:
It is demonstrated that loss of transforming growth factor‐β activated kinase 1 (TAK1) signaling reduces inappropriate tissue formation (heterotopic ossification) through reduced cellular differentiation, and the importance of both the “drug on” and "drug off" states during regenerative therapy is revealed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 22, 2019
2019 journal article
Transcriptome and organellar sequencing highlights the complex origin and diversification of allotetraploid Brassica napus
NATURE COMMUNICATIONS, 10.
MeSH headings : Brassica napus / genetics; Brassica napus / metabolism; Gene Expression Regulation, Plant; Genomics; Organelles; Phylogeny; Plant Leaves / growth & development; Plant Tubers; Ploidies; Polymorphism, Single Nucleotide; RNA, Plant / genetics; Sequence Analysis, RNA; Transcriptome
TL;DR:
The authors show the complex origin and diversification of Brassica napus by analyzing transcriptome and organellar sequencing data and discern regions with signatures of selective sweeps and detect 8,187 differentially expressed genes with implications for B. napus diversification.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2019
2019 journal article
Landscape patterns in top-down control of decomposition: omnivory disrupts a tropical detrital-based trophic cascade
ECOLOGY, 100(7).
MeSH headings : Animals; Biomass; Ecosystem; Plant Leaves; Poecilia; Predatory Behavior; Trinidad and Tobago
TL;DR:
Top-down effects of three macroconsumer species on detrital processing in headwater streams draining Trinidad's northern mountains are isolated, revealing that omnivory can result in significant indirect effects on a key ecosystem process and suggesting that resource control in tropical systems may be even more complex than previously envisioned.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: July 22, 2019
2019 journal article
Predicting residual feed intake status using rumen microbial profiles in ewe lambs
JOURNAL OF ANIMAL SCIENCE, 97(7), 2878–2888.
author keywords: feed efficiency; RFI prediction; rumen microbiome; sheep
MeSH headings : Animal Feed / analysis; Animals; Diet / veterinary; Eating; Female; Microbiota; Phenotype; Rumen / microbiology; Sheep / microbiology; Sheep / physiology
TL;DR:
Results indicate that specific rumen microbial species may play a role in feed efficiency, and that a microbial profile could be used to rank sheep for feed efficiency.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2019
2019 journal article
Paleoproteomics of Mesozoic Dinosaurs and Other Mesozoic Fossils
PROTEOMICS, 19(16), 1800251.
author keywords: dinosaurs; fossil; mesozoic; protein; soft tissues
MeSH headings : Animals; Biological Evolution; Bone and Bones / anatomy & histology; Bone and Bones / metabolism; Dinosaurs / anatomy & histology; Dinosaurs / classification; Dinosaurs / metabolism; Fossils; Mass Spectrometry / methods; Paleontology / methods; Proteins / analysis; Proteomics / methods
TL;DR:
The power and potential of a molecular approach to Mesozoic fossils is discussed, and some criteria for assessing the presence of endogenous biomolecules in very ancient fossil remains are suggested as a starting framework for such studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: July 22, 2019
2019 journal article
Functional characterization of SMN evolution in mouse models of SMA
SCIENTIFIC REPORTS, 9.
MeSH headings : Animals; Caenorhabditis elegans; Disease Models, Animal; Drosophila melanogaster; Evolution, Molecular; Mice; Mice, Knockout; Muscular Atrophy, Spinal / genetics; Muscular Atrophy, Spinal / metabolism; Schizosaccharomyces; Survival of Motor Neuron 1 Protein / genetics; Survival of Motor Neuron 1 Protein / metabolism; Xenopus Proteins / genetics; Xenopus Proteins / metabolism; Xenopus laevis; Zebrafish / genetics; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
TL;DR:
A minimal SMN construct was designed consisting of exons 2, 3, and 6, which showed a partial rescue of the SMA phenotype, which suggests that while the core conserved region is essential, additional sequences contribute to the overall ability of the SMN protein to rescue disease pathology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2019
2019 journal article
Resolving misaligned spatial data with integrated species distribution models
ECOLOGY, 100(6).
author keywords: black-throated blue warbler; change of support; Data integration for population models Special Feature; integrated species distribution modeling; occupancy modeling; spatial modeling
TL;DR:
This work examines the issue of misaligned data as it relates specifically to integrated species distribution models, and provides a general solution that builds off work in the statistical literature for the change‐of‐support problem.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2019
2019 journal article
Bone Mineral Density Adult Age Estimation in Forensic Anthropology: A Test of the DXAGE Application
JOURNAL OF FORENSIC SCIENCES, 64(4), 1125–1128.
author keywords: forensic sciences; forensic anthropology; age-at-death estimation; bone mineral density; DXAGE; NHANES
MeSH headings : Absorptiometry, Photon; Adult; Age Determination by Skeleton / methods; Aged; Aged, 80 and over; Bone Density; Datasets as Topic; Female; Femur / diagnostic imaging; Forensic Anthropology; Health Surveys; Humans; Internet; Middle Aged; Software; Young Adult
TL;DR:
While BMD data are potentially useful for predicting age age‐at‐death, the DXAGE application should be used cautiously in forensic anthropological contexts, and there is a weak correlation between predicted and actual age.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: July 22, 2019
2019 journal article
Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases
Toxicology and Applied Pharmacology, 379, 114674.
Contributors: M. Kosnik n & D. Reif n
author keywords: Data integration; Risk assessment; New approach methodologies; Gene-environment interactions
MeSH headings : Animals; Databases, Factual; Datasets as Topic; Environmental Exposure / adverse effects; Environmental Exposure / statistics & numerical data; Gene-Environment Interaction; Genetic Predisposition to Disease / etiology; Genetic Predisposition to Disease / genetics; Genetic Variation; High-Throughput Screening Assays; Humans; Information Storage and Retrieval; Risk Assessment / methods; Toxicology / methods
TL;DR:
This work presents an approach that systematically links multiple data sources to relate chemical risk values to diseases and gene-disease variants and develops a new value that estimates the risk of these associations toward differential population responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: ORCID
Added: July 17, 2019
2019 journal article
Migratory gauntlets on oceanic islands: Watershed disturbance increases the cost of amphidromy
ECOLOGY OF FRESHWATER FISH, 28(3), 446–458.
author keywords: biological invasions; diadromy; Gobiidae; Hawai'i; land use; Poeciliidae
TL;DR:
Densities of native Hawaiian amphidromous fishes are equally or more sensitive to conditions along migratory pathways relative to conditions in primary residential habitats, suggesting alleviating pressures by removing invasive species and restoring habitat along dispersal pathways could be effective approaches to increasing densities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: July 15, 2019
2019 journal article
Interferon-λ3 Promotes Epithelial Defense and Barrier Function Against Cryptosporidium parvum Infection
Cellular and Molecular Gastroenterology and Hepatology, 8(1), 1–20.
author keywords: Cryptosporidiosis; Cytokine; Enterocyte; Protozoa
MeSH headings : Animals; Cell Line; Cryptosporidiosis / genetics; Cryptosporidiosis / immunology; Cryptosporidiosis / parasitology; Cryptosporidium parvum / physiology; Cytokines / genetics; Cytokines / metabolism; Disease Models, Animal; Gene Expression Profiling; Intestinal Mucosa / immunology; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Swine; Up-Regulation
TL;DR:
These studies identify IFN-λ2/3 as a key epithelial defense mechanism against C parvum infection and Priming of IECs with recombinant human IFn-λ3 promoted cellular defense against CParvum infections and abrogated C parVum–induced loss of barrier function by decreasing paracellular permeability to sodium.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: July 15, 2019
2019 review
A Review and Tutorial of Machine Learning Methods for Microbiome Host Trait Prediction
[Review of ]. FRONTIERS IN GENETICS, 10.
author keywords: disease; phenotype; modeling; machine learning; prediction
TL;DR:
The most commonly used machine learning methods are explored, and their prediction accuracy as applied to microbiome host trait prediction is evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 15, 2019
2019 journal article
Development of an Online Experiment Platform for High School Biology
JOURNAL OF FORMATIVE DESIGN IN LEARNING, 3(1), 62–81.
author keywords: Online lab experiments; High school biology; Virtual experiments; Neuroscience; Drugs; Situational interest
TL;DR:
A novel online platform that immerses students in a scientific investigative process, Rex (Real experiments), that uses zebrafish and rats as model systems to study the effects of drugs such as tetrahydrocannabinol, caffeine, alcohol, and cigarette smoke is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Source: Web Of Science
Added: July 8, 2019
2019 journal article
Association of prenatal antibiotics with measures of infant adiposity and the gut microbiome
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, 18.
author keywords: Gut microbiome; Pediatric obesity; Antibiotic; Child health; Prenatal exposure; Pregnancy
MeSH headings : Adiposity / drug effects; Adult; Anti-Bacterial Agents / adverse effects; Bacteria / classification; Bacteria / drug effects; Bacteria / genetics; Bacteria / isolation & purification; Female; Gastrointestinal Microbiome / drug effects; Humans; Infant; Male; Obesity / etiology; Obesity / microbiology; Obesity / physiopathology; Pregnancy; Prenatal Exposure Delayed Effects / etiology; Prenatal Exposure Delayed Effects / microbiology; Prenatal Exposure Delayed Effects / physiopathology; Prospective Studies; Young Adult
TL;DR:
Prenatal antibiotic exposure in the second trimester was associated with an altered infant gut microbiome composition at 3 and 12 months and with higher infant WFL-z and subscapular skinfold thickness at 12 months.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 8, 2019
2019 journal article
A facile strategy for photoactive nanocellulose-based antimicrobial materials
GREEN CHEMISTRY, 21(12), 3424–3435.
TL;DR:
Anti-infective materials based upon renewable nanocellulose–porphyrin conjugates photodynamically inactivated four strains of drug-resistant bacteria and two viruses by 99.999+%.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 8, 2019
2019 journal article
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
NATURE COMMUNICATIONS, 10.
MeSH headings : ADAM17 Protein / antagonists & inhibitors; Antineoplastic Combined Chemotherapy Protocols / pharmacology; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Benchmarking; Biomarkers, Tumor / genetics; Cell Line, Tumor; Computational Biology / methods; Computational Biology / standards; Datasets as Topic; Drug Antagonism; Drug Resistance, Neoplasm / drug effects; Drug Resistance, Neoplasm / genetics; Drug Synergism; Genomics / methods; Humans; Molecular Targeted Therapy / methods; Mutation; Neoplasms / drug therapy; Neoplasms / genetics; Pharmacogenetics / methods; Pharmacogenetics / standards; Phosphatidylinositol 3-Kinases / genetics; Phosphoinositide-3 Kinase Inhibitors; Treatment Outcome
TL;DR:
A large drug combination screen across cancer cell lines is provided to benchmark crowdsourced methods and to computationally predict drug synergies, and genomic rationale for synergy predictions are identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 1, 2019
2019 journal article
Conservation and diversity in expression of candidate genes regulating socially-induced female-male sex change in wrasses
PEERJ, 7.
author keywords: Protogynous sex change; Bluehead wrasse; Spotty wrasse; Kyusen wrasse; Quantitative real-time PCR; Sex-biased gene expression; cyp19a1a; cyp19a1b; amh; Isotocin
TL;DR:
While key components of the molecular machinery controlling gonadal sex change are phylogenetically conserved among wrasses, neural pathways governing behavioural sex change may be more variable.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2019
2019 journal article
Smoking-associated AHRR demethylation in cord blood DNA: impact of CD235a+nucleated red blood cells
CLINICAL EPIGENETICS, 11.
MeSH headings : Adult; Basic Helix-Loop-Helix Transcription Factors / genetics; CpG Islands; DNA Demethylation; Epigenesis, Genetic; Erythrocyte Count; Erythrocytes / immunology; Female; Fetal Blood / immunology; Glycophorins / metabolism; Humans; Lipopolysaccharide Receptors / metabolism; Male; Maternal Age; Pregnancy; Prenatal Exposure Delayed Effects / genetics; Repressor Proteins / genetics; Sequence Analysis, DNA; Smoking / adverse effects; Smoking / genetics; Young Adult
TL;DR:
Prenatal smoke exposure was highly significantly associated with AHRR methylation in cord blood, CD14+ monocytes, and CD235a+ nRBCs, andCD14+ cells, and robust linear regression models adjusting for estimated cell type composition outperformed those lacking these covariates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 1, 2019
2019 journal article
Epigenome-wide meta-analysis of DNA methylation and childhood asthma
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 143(6), 2062–2074.
author keywords: Epigenetics; methylation; asthma; childhood; newborn; drug development
MeSH headings : Asthma / genetics; Child; CpG Islands / genetics; Cross-Sectional Studies; DNA Methylation; ERG1 Potassium Channel / genetics; Epigenesis, Genetic; Epigenome / genetics; Genome-Wide Association Study; Humans; Infant, Newborn; Interleukin-5 Receptor alpha Subunit / genetics
TL;DR:
Novel loci differentially methylated in newborns represent potential biomarkers of risk of asthma by school age, and Asthma-related differential methylation in blood in children was substantially replicated in eosinophils and respiratory epithelium.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 24, 2019
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