Works Published in 2021
Displaying works 141 - 160 of 248 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2021 journal article
Perinatal activation of ER alpha and ER beta but not GPER-1 masculinizes female rat caudate-putamen medium spiny neuron electrophysiological properties
JOURNAL OF NEUROPHYSIOLOGY, 125(6), 2322–2338.
author keywords: < em > caudate putamen <; em >; < em > dorsal striatum <; em >; < em > electrophysiology <; em >; < em > estradiol <; em >; < em > estrogen receptor <; em >
MeSH headings : Animals; Animals, Newborn; Caudate Nucleus / drug effects; Electrophysiological Phenomena / drug effects; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogen Receptor alpha / agonists; Estrogen Receptor alpha / drug effects; Estrogen Receptor beta / agonists; Estrogen Receptor beta / drug effects; Estrogens / administration & dosage; Estrogens / pharmacology; Female; GABAergic Neurons / drug effects; Male; Patch-Clamp Techniques; Putamen / drug effects; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled / drug effects; Sex Characteristics
TL;DR:
It is indicated that perinatal estradiol exposure masculinizes MSN electrophysiological phenotype via activation of ERα and ERβ.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 6, 2021
2021 journal article
A model integrating multiple processes of synchronization and coherence for information instantiation within a cortical area
BIOSYSTEMS, 205.
author keywords: Cortex; Synchronization; Coherence; Network; LFP; Kuramoto model; Information; van Cittert-Zernike
MeSH headings : Animals; Cerebral Cortex / physiology; Cortical Synchronization; Electroencephalography; Humans; Mammals / physiology; Models, Neurological; Nerve Net / physiology; Neural Networks, Computer; Spatio-Temporal Analysis
TL;DR:
The coherent aperture model incorporates considerable reported research, integrating five conceptually and mathematically independent processes: a damped Kuramoto network model, a pumped area field potential, the gating of nearly coincident spikes, the coherence of activity across cortical lamina, and 5) complex information formed through functions in macrocolumns.
(via Semantic Scholar)
Source: Web Of Science
Added: July 6, 2021
2021 journal article
Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology
PLOS COMPUTATIONAL BIOLOGY, 17(7).
Ed(s): V. Hatzimanikatis
MeSH headings : Animals; Computational Biology; Embryo, Nonmammalian / drug effects; High-Throughput Screening Assays; Models, Chemical; Neural Networks, Computer; Toxicity Tests; Toxicology; Zebrafish
TL;DR:
E embryonic zebrafish were used to examine a suite of morphological and mortality endpoints at six concentrations from over 1,000 unique chemicals found in the ToxCast library, and Go-ZT significantly outperformed the cGAN, support vector machine, random forest and multilayer perceptron models in cross-validation, and when tested against an external test dataset.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 5, 2021
2021 journal article
Association between PEG3 DNA methylation and high-grade cervical intraepithelial neoplasia
INFECTIOUS AGENTS AND CANCER, 16(1).
author keywords: Cervical intraepithelial neoplasia; Gene methylation; Imprinted gene; Human papillomavirus
TL;DR:
An association between altered DNA methylation at regulatory regions of PEG3 and high grade CIN in high-risk HPV positive cases is suggested in women enrolled at colposcopic evaluation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: June 28, 2021
2021 journal article
Estimating exposure to neighborhood crime by race and ethnicity for public health research
BMC PUBLIC HEALTH, 21(1).
author keywords: Police-reported crime; Race and ethnicity; Crime exposure; Police; Policing
MeSH headings : Crime; Ethnicity; Humans; Infant, Newborn; North Carolina / epidemiology; Police; Public Health; Residence Characteristics; United States
TL;DR:
Dramatic disparities in exposure to crime based on participant race and ethnicity are demonstrated and variability in these disparities is highlighted based on the type of crime and crime measurement method chosen.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions
(Web of Science)
Source: Web Of Science
Added: June 28, 2021
2021 article
Effects of Prescribed Fire on Northern Bobwhite Nesting Ecology
Rosche, S. B., Moorman, C. E., Kroeger, A. J., Pacifici, K., Jones, J. G., & Deperno, C. S. (2021, June 14). WILDLIFE SOCIETY BULLETIN, Vol. 6.
author keywords: Colinus virginianus; ecological restoration; ground-nesting bird; growing-season fire; longleaf pine; nest-site selection; northern bobwhite; prescribed fire
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 28, 2021
2021 journal article
Disruption of the odorant coreceptor Orco impairs foraging and host finding behaviors in the New World screwworm fly
SCIENTIFIC REPORTS, 11(1).
MeSH headings : Animals; Diptera / metabolism; Diptera / physiology; Feeding Behavior; Host-Seeking Behavior; Insect Proteins / genetics; Insect Proteins / metabolism; Mutation; Phylogeny; Receptors, Odorant / genetics; Receptors, Odorant / metabolism; Smell
TL;DR:
It is shown that the screwworm Orco orthologue (ChomOrco) is highly conserved within Diptera, showing signals of strong purifying selection and broadening the understanding of the chemoreception basis of niche occupancy by blowflies.
(via Semantic Scholar)
Source: Web Of Science
Added: June 28, 2021
2021 journal article
Course-based undergraduate research experiences are a viable approach to increase access to research experiences in biology
Journal of Biological Education, 6, 1–15.
author keywords: Undergraduate; research; cure; expanding access; biology
TL;DR:
In comparing student outcomes from four distinct CUREs to outcomes from students engaged in a summer research programme in the biology department at one institution, it is found that students in both experiences self-report comparable gains on all items studied using the Undergraduate Research Student Self-Assessment tool.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: June 28, 2021
2021 journal article
Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification
Frontiers in Toxicology, 3.
TL;DR:
It is found that combining information from behavioral and mortality assessments captures early signals of potential chemical hazards, obviating the need to evaluate a comprehensive suite of morphological endpoints in initial screens for toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: June 22, 2021
2021 journal article
Three steps to adapt case studies for synchronous and asynchronous online learning
Journal of Microbiology and Biology Education, 22(1), ev22i1-2337.
TL;DR:
This work describes functional examples of a three-step process to prepare cases with defined outcomes for individual student preparation, collaborative learning, and individual student synthesis to create an inclusive learning experience, whether in a traditional or remote learning environment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 21, 2021
2021 article
Antipredator phenotype in crucian carp altered by a psychoactive drug
Vinterstare, J., Bronmark, C., Nilsson, P. A., Langerhans, R. B., Berglund, O., Orjes, J., … Hulthen, K. (2021, June 14). ECOLOGY AND EVOLUTION.
author keywords: antipredator traits; inducible defenses; phenotypic plasticity; psychoactive drugs; serotonergic system; SSRI
TL;DR:
The results highlight that environmental pollution by pharmaceuticals could disrupt physiological regulation of ecologically important inducible defenses, and influence the physiological stress response in a model species, crucian carp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: June 21, 2021
2021 journal article
Divide and Conquer: A Simple Modern Technique for Collaborative Small Group Learning with Reciprocal Peer Teaching
Journal of Microbiology and Biology Education, 22(1), ev22i1-2153.
TL;DR:
Divide and Conquer is a simple, easy-to-use, and modern technique that faculty and instructors can use to rapidly transform traditional lecture content into collaborative small group learning and peer-teaching experiences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 21, 2021
2021 journal article
STAT6-dependent exacerbation of house dust mite-induced allergic airway disease in mice by multi-walled carbon nanotubes
NANOIMPACT, 22.
author keywords: Carbon nanotubes; House dust mite; Allergens; STAT6; Asthma
MeSH headings : Animals; Antigens, Dermatophagoides / adverse effects; Asthma / chemically induced; Dermatophagoides pteronyssinus; Fibrosis; Hypersensitivity / metabolism; Immunoglobulin E; Lung; Male; Metaplasia / chemically induced; Mice; Mice, Knockout; Nanotubes, Carbon / adverse effects; Pulmonary Eosinophilia / chemically induced; Pulmonary Fibrosis / chemically induced; Respiration Disorders / chemically induced; STAT6 Transcription Factor / genetics
TL;DR:
Findings provide new mechanistic insight by demonstrating a requirement for STAT6 in MWCNT-induced exacerbation of allergic respiratory disease by demonstrating that airway fibrosis was significantly increased by the combination of HDM and M WCNTs in WT mice but not in Stat6 KO mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 21, 2021
2021 journal article
Eigenvector-based sparse canonical correlation analysis: Fast computation for estimation of multiple canonical vectors
JOURNAL OF MULTIVARIATE ANALYSIS, 185.
author keywords: GTEx; High-dimensional data analysis; Multivariate regression; Sparse canonical correlation analysis
TL;DR:
This work provides an explicit link between sparse multiple regression with sparse canonical correlation analysis, and an efficient algorithm that can estimate multiple canonical pairs simultaneously rather than sequentially, and naturally allows parallel computing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 19, 2021
2021 journal article
Origin of a Giant Sex Chromosome
MOLECULAR BIOLOGY AND EVOLUTION, 38(4), 1554–1569.
author keywords: sex chromosomes; genome evolution; chromosome evolution; supernumerary chromosome; chromosome fusion; genetic conflict
MeSH headings : Animals; Biological Evolution; Cichlids / genetics; DNA Transposable Elements; Female; Genome; Male; Sex Chromosomes; Synteny
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 14, 2021
2021 journal article
Testing hypothesis of skeletal unity using bone histology: The case of the sauropod remains from the Howe-Stephens and Howe Scott quarries (Morrison Formation, Wyoming, USA)
PALAEONTOLOGIA ELECTRONICA, 24(1).
author keywords: Bone microstructure; intra-specific variability; Upper Jurassic; Diplodocidae; Macronaria
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: June 14, 2021
2021 journal article
The contributions from the progenitor genomes of the mesopolyploid Brassiceae are evolutionarily distinct but functionally compatible
GENOME RESEARCH, 31(5), 799–810.
MeSH headings : Evolution, Molecular; Genome; Genome, Plant; Humans; Hybridization, Genetic; Phylogeny; Polyploidy
TL;DR:
A “mix and match” model of allopolyploidy is proposed, in which subgenome origin drives homoeolog loss propensities but where genes from different subgenomes function together without difficulty.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021
2021 journal article
Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms
ACS OMEGA, 6(11), 7454–7468.
TL;DR:
Tilorone and pyronaridine inhibited the virus replication in A549-ACE2 cells with IC50 values of 180 nM and IC50 198 nM, respectively and novel insights are provided into the mechanism of these compounds which is likely lysosomotropic.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021
2021 journal article
Smoke-Free Home Rules and Association with Child Secondhand Smoke Exposure among Mother-Child Dyad Relationships
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(10).
author keywords: smoke-free home; smoke-free home rules; child secondhand smoke exposure; salivary cotinine; household smokers; smoking mothers
MeSH headings : Child; Female; Humans; Longitudinal Studies; Mother-Child Relations; North Carolina; Saliva / chemistry; Tobacco Smoke Pollution / analysis
TL;DR:
Smoke-free home rules are not sufficient to fully protect children from secondhand smoke exposure, especially in homes with smokers, and future research should focus on how household members who smoke can facilitate the prevention of child second hand smoke exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021
2021 journal article
Understanding the influence of multiple pollutant stressors on the decline of freshwater mussels in a biodiversity hotspot
SCIENCE OF THE TOTAL ENVIRONMENT, 773, 144757.
author keywords: Unionidae; Habitat; Metals; Organic contaminants; Clinch River
MeSH headings : Animals; Biodiversity; Bivalvia; Environmental Monitoring; Environmental Pollutants; Fresh Water; Tennessee; Virginia; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / toxicity
TL;DR:
This study revealed that PAHs and Mn are important pollutant stressors to mussels in the Clinch River and that they are largely being delivered through the Guest River tributary watershed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021
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