College of Veterinary Medicine - General

Works Published in 2017

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Displaying works 21 - 28 of 28 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 journal article

Pilot study to determine the feasibility of radiation therapy for dogs with right atrial masses and hemorrhagic pericardial effusion

JOURNAL OF VETERINARY CARDIOLOGY, 19(2), 132–143.

author keywords: Heart-base tumor; Cardiac hemangiosarcoma; Canine
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / radiotherapy; Dogs; Echocardiography; Female; Heart Atria; Heart Neoplasms / complications; Heart Neoplasms / radiotherapy; Heart Neoplasms / veterinary; Hemangiosarcoma / complications; Hemangiosarcoma / radiotherapy; Hemangiosarcoma / veterinary; Hemorrhage / complications; Hemorrhage / veterinary; Male; Pericardial Effusion / complications; Pericardial Effusion / veterinary; Pilot Projects; Postoperative Complications / veterinary; Treatment Outcome
TL;DR: RT alone, or in combination with chemotherapy, may provide clinical benefit to dogs with presumptive diagnoses of cardiac hemangiosarcoma, and appears to have reduced the frequency of periacardial tamponade that necessitated pericardiocentesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Efficacy of an Escherichia coli O157:H7 SRP Vaccine in Orally Challenged Goats and Strain Persistence Over Time

FOODBORNE PATHOGENS AND DISEASE, 14(3), 160–166.

author keywords: Shiga toxin-producing E. coli; goats; livestock exhibition; vaccination
MeSH headings : Administration, Oral; Animals; Bacterial Outer Membrane Proteins / immunology; Electrophoresis, Gel, Pulsed-Field; Escherichia coli Infections / prevention & control; Escherichia coli Infections / veterinary; Escherichia coli O157 / immunology; Escherichia coli Proteins / genetics; Escherichia coli Proteins / immunology; Escherichia coli Vaccines / immunology; Feces / microbiology; Food Contamination / prevention & control; Food Microbiology; Goat Diseases / microbiology; Goat Diseases / prevention & control; Goats / immunology; Goats / microbiology; Male; Milk / microbiology; Porins / immunology; Receptors, Cell Surface / immunology; Red Meat / microbiology; Vaccination / veterinary
TL;DR: Further work is needed to evaluate cost-effective intervention strategies that reliably reduce E. coli O157:H7 shedding in goats, particularly those that may reduce the risk of transmission at public events, including petting zoos and fairs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Stomach curvature is generated by left-right asymmetric gut morphogenesis

DEVELOPMENT, 144(8), 1477–1483.

author keywords: Left-right; Asymmetry; Stomach; Gut; Morphogenesis; Pitx2; Xenopus; Mouse
MeSH headings : Animals; Body Patterning; Endoderm / embryology; Endoderm / metabolism; Epithelium / embryology; Epithelium / metabolism; Homeodomain Proteins / metabolism; Mice; Rotation; Signal Transduction; Stomach / anatomy & histology; Stomach / embryology; Transcription Factors / metabolism; Xenopus / embryology
TL;DR: It is shown that the mechanisms that drive the curvature of the stomach are intrinsic to the gut tube itself, and this findings have implications for how LR patterning manifests distinct types of morphological asymmetries in different contexts. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease-associated pain

VETERINARY RECORD, 180(19).

MeSH headings : Analgesics / therapeutic use; Animals; Caregivers / psychology; Cat Diseases / drug therapy; Cats; Female; Humans; Joint Diseases / complications; Joint Diseases / veterinary; Male; Optimism; Osteoarthritis / complications; Osteoarthritis / veterinary; Pain / drug therapy; Pain / etiology; Pain / veterinary; Placebo Effect; Treatment Outcome
TL;DR: The caregiver placebo effect across these clinical trials was remarkably high, making demonstration of efficacy for an analgesic above a placebo difficult, and further work is needed to determine whether a potential placebo-by-proxy effect could benefit cats in clinical settings. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Thromboelastographic monitoring of the effect of unfractionated heparin in healthy dogs

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 27(1), 71–81.

author keywords: anticoagulation monitoring; anti-Xa; canine; RapidTEG; thrombosis
MeSH headings : Animals; Anticoagulants / administration & dosage; Anticoagulants / pharmacology; Blood Coagulation / drug effects; Dogs; Female; Heparin / administration & dosage; Heparin / pharmacology; Injections, Subcutaneous / veterinary; Male; Partial Thromboplastin Time / veterinary; Prospective Studies; Reference Values; Thrombelastography / veterinary
TL;DR: This study demonstrates that TEG variables derived using robust activation correlate with AXa activity as well as aPTT and have the potential to be used for monitoring UFH therapy in healthy dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 article

Severity scoring of manganese health effects for categorical regression

Mattison, D. R., Milton, B., Krewski, D., Levy, L., Dorman, D. C., Aggett, P. J., … McGough, D. (2017, January). NEUROTOXICOLOGY, Vol. 58, pp. 203–216.

By: D. Mattison*, B. Milton, D. Krewski*, L. Levy*, D. Dorman n, P. Aggett*, H. Roels*, M. Andersen* ...

author keywords: Exposure-response assessment; Categorical regression; Database; Manganese toxicity
MeSH headings : Animals; Copper / toxicity; Databases, Factual; Dose-Response Relationship, Drug; Environmental Exposure; Female; Humans; Male; Manganese / toxicity; Manganese Poisoning / etiology; Regression Analysis
TL;DR: The development of a database on Mn toxicity designed to support the application of categorical regression techniques is documents, providing a comprehensive repository of exposure‐response information with the ability to support categorically regression modeling of oral exposure data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Evaluation of the Lactate Plus monitor for plasma lactate concentration measurement in dogs

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 27(1), 66–70.

By: C. Nye n, S. Musulin n, R. Hanel n & C. Mariani n

author keywords: canine; metabolic acidosis; perfusion; point of care; shock; validation
MeSH headings : Animals; Blood Gas Analysis / instrumentation; Blood Gas Analysis / veterinary; Dogs; Emergency Medical Services; Female; Lactic Acid / blood; Male; Monitoring, Physiologic / instrumentation; Monitoring, Physiologic / veterinary; Point-of-Care Systems; Prospective Studies; Reproducibility of Results
TL;DR: The Lactate Plus provides a fast and affordable method to measure plasma lactate concentration in dogs and shows excellent agreement with the reference analyzer and precision of the instrument was acceptable. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Demonstration of rebound phenomenon following abrupt withdrawal of the JAK1 inhibitor oclacitinib

EUROPEAN JOURNAL OF PHARMACOLOGY, 794, 20–26.

author keywords: JAK-inhibitor; Oclacitinib; Itch; Rebound phenomenon; Allergic dermatitis; TRPV1
MeSH headings : Animals; Behavior, Animal / drug effects; CD11c Antigen / metabolism; Calcium / metabolism; Cytokines / metabolism; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Dendritic Cells / pathology; Female; Ganglia, Spinal / drug effects; Ganglia, Spinal / pathology; Immunomodulation / drug effects; Intracellular Space / drug effects; Intracellular Space / metabolism; Janus Kinase 1 / antagonists & inhibitors; Mice; Mice, Inbred BALB C; Protein Kinase Inhibitors / pharmacology; Protein Kinase Inhibitors / therapeutic use; Pruritus / drug therapy; Pruritus / immunology; Pruritus / pathology; Pyrimidines / pharmacology; Pyrimidines / therapeutic use; Sensory Receptor Cells / drug effects; Sensory Receptor Cells / pathology; Skin / drug effects; Skin / immunology; Skin / metabolism; Sulfonamides / pharmacology; Sulfonamides / therapeutic use; Tumor Necrosis Factor-alpha / metabolism
TL;DR: While oclacitinib significantly reduced itch during treatment the abrupt withdrawal led to a rapid rebound phenomenon which can be explained by an increase in pruritogenic cytokines and fast peripheral sensitization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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