Works Published in 2015

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Displaying works 1 - 20 of 56 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 chapter

Concept and history of genetic control

In Genetic control of malaria and dengue (pp. 31–54). Elsevier.

By: M. Scott & M. Benedict

Source: ORCID
Added: January 29, 2024

2015 journal article

CRISPR/Cas9-mediated mutagenesis of the white and Sex lethal loci in the invasive pest, Drosophila suzukii

Biochemical and Biophysical Research Communications.

Maxwell Scott

MeSH headings : ATP-Binding Cassette Transporters / genetics; Animals; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Drosophila / classification; Drosophila / genetics; Drosophila Proteins / genetics; Eye Color / genetics; Eye Proteins / genetics; Female; Male; Mutagenesis, Site-Directed / methods; Quantitative Trait Loci / genetics; RNA-Binding Proteins / genetics; Sex Characteristics
TL;DR: The D. suzukii Sxl gene could be an excellent target for a Cas9-mediated gene drive to suppress populations of this highly destructive pest. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: January 29, 2024

2015 journal article

CESA TRAFFICKING INHIBITOR Inhibits Cellulose Deposition and Interferes with the Trafficking of Cellulose Synthase Complexes and Their Associated Proteins KORRIGAN1 and POM2/CELLULOSE SYNTHASE INTERACTIVE PROTEIN

Plant Physiology, 167(2), 381–393.

By: N. Worden*, T. Wilkop*, V. Esteve*, R. Jeannotte*, R. Lathe*, S. Vernhettes*, B. Weimer*, G. Hicks* ...

MeSH headings : Anisotropy; Arabidopsis / cytology; Arabidopsis / enzymology; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / metabolism; Benzamides / pharmacology; Carrier Proteins / metabolism; Cell Compartmentation / drug effects; Cell Membrane / drug effects; Cell Membrane / metabolism; Cellulase / metabolism; Cellulose / metabolism; Dinitrobenzenes / pharmacology; Enzyme Inhibitors / pharmacology; Glucose / metabolism; Glucosyltransferases / metabolism; Green Fluorescent Proteins / metabolism; Hypocotyl / drug effects; Hypocotyl / metabolism; Membrane Proteins / metabolism; Microtubules / drug effects; Microtubules / metabolism; Multiprotein Complexes / metabolism; Protein Transport / drug effects; Sulfanilamides / pharmacology
TL;DR: A unique small molecule, CESA TRAFFICKING INHIBITOR (CESTRIN), which reduces cellulose content and alters the anisotropic growth of Arabidopsis hypocotyls and afford unique avenues to study and understand the mechanism under which PM-associated CSCs are maintained and interact with MTs and to dissect their trafficking routes in etiolated hypocotYLs. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: October 9, 2021

2015 journal article

Signatures of adaptation to plant parasitism in nematode genomes

Parasitology, 142(S1), S71–S84.

author keywords: nematodes; genomes; plant parasitism; adaptation; convergence
MeSH headings : Adaptation, Physiological; Animals; Genomics; Host-Parasite Interactions; Nematoda / genetics; Nematoda / physiology; Phylogeny; Plants / parasitology
TL;DR: Overall, nematodes appear to have developed convergent genomic solutions to adapt to plant parasitism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
Source: Crossref
Added: November 26, 2020

2015 journal article

Genetic basis of natural variation in body pigmentation in Drosophila melanogaster

Fly, 9(2), 75–81.

By: L. Dembeck n, W. Huang n, M. Carbone n & T. Mackay n

author keywords: Drosophila melanogaster Genetic Reference Panel; extreme QTL mapping; genome wide association study; quantitative genetics; replication study
MeSH headings : Abdomen; Animals; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Female; Gene Expression Regulation / physiology; Genome-Wide Association Study; Pigmentation / genetics; Pigmentation / physiology; Polymorphism, Single Nucleotide; Quantitative Trait Loci
TL;DR: The results of an extreme quantitative trait locus (xQTL) GWA analysis of female body pigmentation in an outbred population derived from light and dark DGRP lines are described. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2015 journal article

Genetic basis of transcriptome diversity in Drosophila melanogaster

Proceedings of the National Academy of Sciences, 112(44), E6010–E6019.

By: W. Huang n, M. Carbone n, M. Magwire n, J. Peiffer n, R. Lyman n, E. Stone n, R. Anholt n, T. Mackay n

author keywords: genome-wide association; novel transcribed regions; mean eQTLs; variance eQTLs; epistasis
MeSH headings : Animals; Drosophila melanogaster / genetics; Epistasis, Genetic; Quantitative Trait Loci; Transcriptome
TL;DR: High complexity of the genetic control of gene expression is found, including widespread sexual dimorphism, highly modularized expression patterns with involvement of novel RNA transcripts, and frequent epistatic interactions among expression quantitative trait loci (QTLs) which often give rise to variance expression QTLs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Crossref
Added: February 24, 2020

2015 journal article

Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior

Proceedings of the National Academy of Sciences, 112(27), E3555–E3563.

author keywords: Drosophila Genetic Reference Panel; genome-wide association mapping; extreme QTL mapping; advanced intercross population; epistasis
MeSH headings : Aggression; Animals; Crosses, Genetic; Drosophila Proteins / genetics; Drosophila Proteins / physiology; Drosophila melanogaster / classification; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic; Evolution, Molecular; Genes, Insect / genetics; Genes, Insect / physiology; Genetic Variation; Genome, Insect / genetics; Humans; Inbreeding; Mutation; RNA Interference; Species Specificity
TL;DR: This work performed genome-wide association analyses using the inbred, sequenced lines of the Drosophila melanogaster Genetic Reference Panel and an advanced intercross population derived from the most and least aggressive DGRP lines to identify genes that have been previously implicated in aggressive behavior as well as many novel loci. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Crossref
Added: February 24, 2020

2015 journal article

Development of Abamectin Loaded Plant Virus Nanoparticles for Efficacious Plant Parasitic Nematode Control

ACS Applied Materials & Interfaces, 7(18), 9546–9553.

By: J. Cao n, R. Guenther n, T. Sit n, S. Lommel n, C. Opperman n & J. Willoughby n

author keywords: red clover necrotic mosaic virus (RCNMV); plant virus nanoparticle (PVN); abamectin; soil mobility; crop protection
MeSH headings : Animals; Biological Availability; Caenorhabditis elegans / drug effects; Capsid / chemistry; Crops, Agricultural / drug effects; Crops, Agricultural / parasitology; Ivermectin / analogs & derivatives; Ivermectin / pharmacology; Solanum lycopersicum / drug effects; Solanum lycopersicum / parasitology; Nanoparticles / chemistry; Nematoda / drug effects; Pest Control, Biological; Plant Diseases / parasitology; Plant Viruses / chemistry; Soil; Suspensions; Tobacco / drug effects; Tobacco / parasitology; Tylenchoidea / drug effects
TL;DR: Tomato seedlings treated with PVN(Abm) had healthier root growth and a reduction in root galling demonstrating the success of this delivery system for the increased efficacy of Abm to control nematode damage in crops. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: February 24, 2020

2015 chapter

A Stacking-Based Approach to Identify Translated Upstream Open Reading Frames in Arabidopsis Thaliana

In Bioinformatics Research and Applications (Vol. 9096, pp. 138–149).

Contributors: Q. Hu n, C. Merchante n, A. Stepanova n, J. Alonso n & S. Heber n

author keywords: uORF; Translation; Ribosome footprinting; Stacking; Classification; Arabidopsis thaliana
TL;DR: This paper uses ribosome footprinting together with a stacking-based classification approach to identify translated uORFs in Arabidopsis thaliana, resulting in a set of 5360 potentially translated u ORFs in 2051 genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 19, 2019

2015 book

Molecular basis of fruit development

In Frontiers Research Topics.

Robert Franks

Ed(s): Z. Liu & R. Franks

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: January 22, 2019

2015 conference paper

Mining transcript features related to translation in Arabidopsis using LASSO and random forest

2015 IEEE 5th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2015.

TL;DR: It is found that the contribution of features may be different for transcripts belonging to different functional groups, suggesting that transcripts might employ different mechanisms for the regulation of translation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Maize Homologs of Hydroxycinnamoyltransferase, a Key Enzyme in Lignin Biosynthesis, Bind the Nucleotide Binding Leucine-Rich Repeat Rp1 Proteins to Modulate the Defense Response

Plant Physiol, 169(3), 2230–2243.

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

The Pacific decadal oscillation and changes in anchovy populations in the Northwest Pacific

Journal of Asian Earth Sciences, 114, 504–511.

By: X. Zhou, Y. Sun, W. Huang, J. Smol, Q. Tang & L. Sun

Source: NC State University Libraries
Added: August 6, 2018

2015 book

Plant functional genomics: Methods and protocols

In J. M. Alonso & A. N. Stepanova (Eds.), Plant Functional Genomics: Methods and Protocols: Second Edition (2nd ed., pp. 1–526).

By: J. Alonso & A. Stepanova*

Contributors: J. Alonso & A. Stepanova*

Ed(s): J. Alonso & A. Stepanova*

TL;DR: This chapter describes an approach to map chromatin features in specifi c cell types of Arabidopsis thaliana using nuclei purifi cation from individual cell types with the INTACT method followed by chromatin immunoprecipitation and high-throughput sequencing (ChIP-seq). (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Plant functional genomics methods and protocols second edition preface

Plant Functional Genomics: Methods and Protocols, 2nd Edition, 1284, V-.

By: J. Alonso & A. Stepanova

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Metabolomic and gene expression profiles exhibit modular genetic and dietary structure linking metabolic syndrome phenotypes in Drosophila

G3-Genes Genomes Genetics, 5(12), 2817–2829.

By: S. Williams, K. Dew-Budd, K. Davis, J. Anderson, R. Bishop, K. Freeman, D. Davis, K. Bray ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Mucosal Immunogenicity of Genetically Modified Lactobacillus acidophilus Expressing an HIV-1 Epitope within the Surface Layer Protein

PLOS ONE, 10(10).

MeSH headings : Adaptive Immunity; Animals; Antibodies, Bacterial / immunology; Antibody Formation / immunology; Antibody Specificity / immunology; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Cytokines / metabolism; Epitopes / genetics; Epitopes / immunology; HIV-1 / genetics; HIV-1 / immunology; Humans; Immunity, Mucosal; Immunization; Immunoglobulin A / immunology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / immunology; Mice; Models, Animal; Mucous Membrane / immunology; Mucous Membrane / microbiology; Mucous Membrane / virology; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / immunology
TL;DR: The constructed genetically modified Lactobacillus acidophilus strains expressing the membrane proximal external region (MPER) from human immunodeficiency virus type 1 (HIV-1) within the context of the major S-layer protein, SlpA, demonstrated the potential use of the LactOBacillus S- layer protein for development of oral vaccines targeting specific peptides. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Dosage Compensation of X-Linked Muller Element F Genes but Not X-Linked Transgenes in the Australian Sheep Blowfly

PLOS ONE, 10(10), e0141544.

By: R. Linger n, E. Belikoff n & M. Scott n

Ed(s): G. Marais

MeSH headings : Animals; Animals, Genetically Modified; Diptera / genetics; Dosage Compensation, Genetic; Drosophila melanogaster / genetics; Female; Gene Expression Regulation, Developmental; Genes, X-Linked / genetics; Larva; Male; X Chromosome / genetics
TL;DR: It appears that the Lucilia dosage compensation system is specific for genes endogenous to the X chromosome and cannot be co-opted by recently arrived transgenes. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2015 journal article

A transgenic embryonic sexing system for the Australian sheep blow fly Lucilia cuprina

Scientific Reports, 5(1).

By: Y. Yan n & M. Scott n

MeSH headings : Animals; Animals, Genetically Modified / genetics; Australia; Diptera / drug effects; Diptera / genetics; Female; Genes, Insect / drug effects; Genes, Insect / genetics; Genes, Lethal / drug effects; Genes, Lethal / genetics; Male; Pest Control, Biological / methods; Pupa / drug effects; Pupa / genetics; Sexual Behavior / physiology; Sheep / parasitology; Tetracycline / pharmacology; Transgenes / drug effects; Transgenes / genetics
TL;DR: Embryonic sexing strains were made by combining the Lsbnk-tTA and tetO-Lshid components into a single gene construct, which will facilitate transfer of the technology to other major calliphorid livestock pests. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2015 conference paper

A stacking-based approach to identify translated upstream open reading frames in Arabidopsis thaliana

Bioinformatics research and applications (isbra 2015), 9096, 138–149.

By: Q. Hu, C. Merchante, A. Stepanova, J. Alonso & S. Heber

Source: NC State University Libraries
Added: August 6, 2018

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