Works Published in 2020

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Displaying works 1 - 20 of 45 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

Core commitments for field trials of gene drive organisms

Science, 370(6523), 1417–1419.

By: K. Long, L. Alphey, G. Annas, C. Bloss, K. Campbell, J. Champer, C. Chen, A. Choudhary ...

MeSH headings : Animals; Gene Drive Technology / standards; Guidelines as Topic; Organisms, Genetically Modified; Safety
TL;DR: Significant commitments are outlined that are deemed critical for responsible conduct of a field trial and to ensure that these technologies, if they are introduced, serve the public interest. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 30, 2024

2020 chapter book

Conditional Expression Systems for Drosophila suzukii Pest Control

By: S. Jaffri*, Y. Yan*, M. Scott n & M. Schetelig*

Sources: Crossref, NC State University Libraries
Added: January 30, 2024

2020 journal article

Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects

G3 Genes|Genomes|Genetics, 10(4), 1271–1281.

By: K. Knudsen, W. Reid n, T. Barbour, L. Bowes, J. Duncan, E. Philpott, S. Potter, M. Scott n

TL;DR: The data suggest that standing genetic variation in an insect population could provide multiple mechanisms for resistance to the tTA overexpression system, and specifically genes associated with RNA processing and rRNA maturation were significantly upregulated in low lethal lines. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: January 29, 2024

2020 journal article

Development and testing of a novel killer–rescue self-limiting gene drive system in <i>Drosophila melanogaster

Proceedings of the Royal Society B: Biological Sciences, 287(1925), 20192994.

By: S. Webster n, M. Vella n & M. Scott n

TL;DR: It is demonstrated that with a single 2:1 engineered to wildtype release, more than 98% of the population carry R after eight generations, and this simple gene drive system could be readily adapted to other species such as mosquito disease vectors for driving anti-viral or anti-parasite genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: January 29, 2024

2020 journal article

Developmental Analysis of Mimulus Seed Transcriptomes Reveals Functional Gene Expression Clusters and Four Imprinted, Endosperm-Expressed Genes

Frontiers in Plant Science, 11.

By: M. Flores-Vergara n, E. Oneal*, M. Costa*, G. Villarino*, C. Roberts*, M. Balaguer n, S. Coimbra*, J. Willis*, R. Franks n

author keywords: seed development; ribonucleic acid sequencing; developmental time course analysis; endosperm; genomic imprinting; K-means clustering; MADS-box genes; Mimulus guttatus
TL;DR: This study is the first to validate genes with imprinted endosperm expression in Mimulus guttatus, and will inform future studies on the genetic causes of seed failure in this model system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: ORCID
Added: February 9, 2023

2020 chapter

RiboSimR: A Tool for Simulation and Power Analysis of Ribo-seq Data

In I. Măndoiu, T. Murali, G. Narasimhan, S. Rajasekaran, P. Skums, & A. Zelikovsky (Eds.), Computational Advances in Bio and Medical Sciences (pp. 121–133).

By: P. Perkins n, A. Stepanova n, J. Alonso n & S. Heber n

Ed(s): I. Măndoiu, T. Murali, G. Narasimhan, S. Rajasekaran, P. Skums & A. Zelikovsky

Event: ICCABS 2019

TL;DR: A power assessment tool, called RiboSimR, that produces semi-parametric simulations that generate data based on real RNA and Ribo-seq experiments, with customizable choices on baseline parameters and tool configurations is proposed. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: October 9, 2021

2020 journal article

Gibberellin-mediated RGA-LIKE1 degradation regulates embryo sac development in Arabidopsis

JOURNAL OF EXPERIMENTAL BOTANY, 71(22), 7059–7072.

By: M. Dolores Gomez*, D. Barro-Trastoy*, C. Fuster-Almunia*, P. Tornero, J. Alonso n & M. Perez-Amador*

author keywords: Arabidopsis; DELLA; development; embryo sac; gibberellin; megagametogenesis; ovule; RGL1
MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Gene Expression Regulation, Plant; Gibberellins; Ovule / genetics; Ovule / metabolism
TL;DR: New genetic tools to study R GL1 expression and function through plant development allowed the uncovering of an RGL1-specific role in the control of female gametophyte development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: February 15, 2021

2020 article

miRNAs explain the variation in muscle and blood transcriptomes of beef calves born from dams with or without energy restriction during late gestation

Carvalho, E. B., Sanglard, L. P., Nascimento, M., Moriel, P., Sommer, J., Merrill, M., … Serao, N. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 165–165.

author keywords: Fetal-programming; maternal nutrition; post-transcriptional regulation
TL;DR: Using RNA-seq data, a large amount of the variation of DEGs was identified, with the identification of important miRNAs related to muscle development and immune system and MiR-21 regulates immune system by different pathways. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: February 8, 2021

2020 article

Effects of genetic selection for early puberty on the hypothalamic-pituitary-ovarian axis in gilts

Harlow, K. L., Renwick, A., Shuping, S., Sommer, J., Knauer, M., & Nestor, C. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 212–212.

By: K. Harlow n, A. Renwick n, S. Shuping n, J. Sommer n, M. Knauer n & C. Nestor n

author keywords: puberty; gilt; neuroendocrine
TL;DR: It is concluded that gilts genetically selected for early puberty do so via changes within the hypothalamus that increase gonadotropin secretion and, in turn, stimulate ovarian growth to ultimately advance the timing of puberty onset. (via Semantic Scholar)
Source: Web Of Science
Added: February 8, 2021

2020 journal article

An early female lethal system of the New World screwworm, Cochliomyia hominivorax, for biotechnology-enhanced SIT

BMC Genetics, 21(S2).

By: C. Concha*, Y. Yan*, A. Arp, E. Quilarque, A. Sagel, A. de León*, W. McMillan*, S. Skoda, M. Scott n

author keywords: Transgenic sexing strain; Pest control; Female lethal strain
MeSH headings : Animals; Animals, Genetically Modified; Biotechnology; Diptera / embryology; Diptera / genetics; Embryonic Development; Female; Genes, Lethal; Genetic Fitness; Infertility / genetics; Insect Control; Male; Promoter Regions, Genetic; Tetracycline
TL;DR: The research team demonstrated the utility of biotechnology-enhanced approaches for SIT by developing a male-only strain of the New World Screwworm fly that carried a single component tetracycline repressible female lethal system where females died at late larval/pupal stages. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: January 19, 2021

2020 journal article

Building a transgenic sexing strain for genetic control of the Australian sheep blow fly Lucilia cuprina using two lethal effectors

BMC Genetics, 21(S2).

By: Y. Yan n & M. Scott n

author keywords: Sterile insect technique (SIT); Tetracycline transactivator (tTA); Head involution defective (hid); Genetic pest management
MeSH headings : Animals; Animals, Genetically Modified; Calliphoridae / embryology; Calliphoridae / genetics; Embryonic Development; Female; Genes, Lethal; Genetic Fitness; Insect Control; Sheep / parasitology; Tetracycline / pharmacology
TL;DR: The combination of two tTA-dependent lethal effectors could improve strain stability under mass rearing and could reduce the risk of resistance in the field if fertile males are released. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: January 19, 2021

2020 journal article

Deeply Sequenced Infectious Clones of Key Cassava Begomovirus Isolates from Cameroon

MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 9(46).

TL;DR: This work deeply sequenced two pairs of widely used infectious clones (4 plasmids) of the bipartite begomoviruses African cassava mosaic virus (ACMV) and East AfricanCassava mosaic Cameroon virus (EACMCV). (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: January 11, 2021

2020 journal article

Physiological and molecular correlates of the screwworm fly attraction to wound and animal odors

Scientific Reports, 10(1).

By: P. Hickner*, O. Mittapalli*, A. Subramoniam*, A. Sagel, W. Watson n, M. Scott n, A. Arp*, A. de León*, Z. Syed*

MeSH headings : Animals; Behavior, Animal; Diptera / classification; Diptera / drug effects; Diptera / physiology; Female; Gene Expression Regulation; Male; Odorants / analysis; Pheromones / metabolism; Pheromones / pharmacology; RNA-Seq; Wounds and Injuries / metabolism
TL;DR: Insight is provided into the physiological and molecular correlates of the screwworm’s attraction to wounds, and molecular targets that will aid in the development of odorant-based fly management strategies are identified. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: January 4, 2021

2020 journal article

Leveraging Multiple Layers of Data To Predict Drosophila Complex Traits

G3-GENES GENOMES GENETICS, 10(12), 4599–4613.

author keywords: Genomic prediction; Transcriptomic prediction; Gene Ontology informed prediction; Drosophila Genetic Reference Panel; GenPred; Shared data resources
MeSH headings : Animals; Drosophila; Drosophila melanogaster / genetics; Female; Genotype; Male; Models, Genetic; Multifactorial Inheritance; Phenotype; Polymorphism, Single Nucleotide
TL;DR: This study shows that integrating different sources of information can improve prediction accuracy, especially when large samples are not available, as well as a limited number of GO terms were strongly predictive of the traits. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: January 4, 2021

2020 journal article

Using Moderate Transgene Expression to Improve the Genetic Sexing System of the Australian Sheep Blow Fly Lucilia cuprina

Insects, 11(11), 797.

By: Y. Yan*, M. Williamson n & M. Scott n

author keywords: livestock pest; Lucilia cuprina; genetic control; pro-apoptotic gene; sterile insect technique; genetic sexing; tetracycline-off system; insect transgenesis
TL;DR: It is shown that effective male-only strains can be made by combining driver/effector lines that have moderate transgene expression/activity, and such a “moderate strategy” could be considered for the TESS development in other pest species. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: December 21, 2020

2020 journal article

Interactive Effects of Elevated Ozone and Temperature on Growth and Yield of Soybean (Glycine max (L.) Merr.) under Field Conditions

AGRONOMY-BASEL, 10(11).

author keywords: biomass; harvest index; ozone; seed yield; soybean; temperature
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: December 14, 2020

2020 journal article

Genotype by environment interaction for gene expression in Drosophila melanogaster

NATURE COMMUNICATIONS, 11(1).

MeSH headings : Animals; Drosophila melanogaster / genetics; Female; Gene Expression; Gene Expression Regulation; Gene Regulatory Networks; Gene-Environment Interaction; Genes, Insect; Genetic Variation; Genotype; Male; Quantitative Trait Loci; RNA-Seq; Temperature; Transcriptome
TL;DR: It is shown that developing under different temperatures changes the genetic architecture of regulatory variation in Drosophila melanogaster gene expression yet the co- expression network remains robust, and data suggest that stabilizing selection on gene expression may promote co-expression network robustness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 30, 2020

2020 journal article

Assembly of whole-chromosome pseudomolecules for polyploid plant genomes using outbred mapping populations

NATURE GENETICS, 52(11), 1256-+.

MeSH headings : Algorithms; Chromosomes, Plant; Computer Simulation; Genetic Linkage; Genome, Plant; Genotype; Ipomoea / genetics; Plant Breeding; Poaceae / genetics; Polyploidy; Protein Array Analysis; Solanum tuberosum / genetics
TL;DR: PolyGembler, a method for grouping and ordering contigs into complete pseudomolecules by combining long-read sequencing and genotype information from an outbred mapping population, improves the accuracy for assembly of polyploidy plant genomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: November 24, 2020

2020 article

Cyst nematode bio-communication with plants: implications for novel management approaches

PEST MANAGEMENT SCIENCE.

By: J. Ochola*, D. Coyne*, L. Cortada*, S. Haukeland*, M. Ng'ang'a*, A. Hassanali*, C. Opperman n, B. Torto*

MeSH headings : Animals; Communication; Cysts; Nematoda; Pest Control; Plants
TL;DR: Cyst nematode hatching and successful infection of hosts are biological processes that are largely influenced by semiochemicals including hatching stimulators, hatching inhibitors, attractants and repellents, which can be used to disrupt interactions between host plants and cyst Nemesis. (via Semantic Scholar)
Source: Web Of Science
Added: November 24, 2020

2020 journal article

Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

PLOS GENETICS, 16(10).

By: E. Wear n, J. Song, G. Zynda, L. Mickelson-Young n, C. LeBlanc*, T. Lee n, D. Deppong n, G. Allen n ...

MeSH headings : Cell Nucleus / drug effects; Cell Nucleus / genetics; Centromere / drug effects; Centromere / genetics; DNA Replication / drug effects; DNA Replication / genetics; DNA Replication Timing / drug effects; DNA Replication Timing / genetics; DNA, Plant / drug effects; DNA, Plant / genetics; Deoxyuridine / analogs & derivatives; Deoxyuridine / pharmacology; Endocytosis / drug effects; Meristem / drug effects; Meristem / genetics; Mitosis / drug effects; Mitosis / genetics; Nucleosomes / drug effects; Plant Roots / drug effects; Plant Roots / genetics; Plant Roots / growth & development; S Phase / genetics; Zea mays / genetics; Zea mays / growth & development
Sources: Web Of Science, NC State University Libraries
Added: November 9, 2020

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