Works Published in 2016
Displaying works 61 - 80 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 review
Infrared matrix-assisted laser desorption electrospray ionization mass spectrometry imaging analysis of biospecimens
[Review of ]. ANALYST, 141(18), 5236–5245.
MeSH headings : Histocytological Preparation Techniques; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
TL;DR:
Challenges and limitations of MSI using IR-MALDESI are addressed in the context of the bioimaging field and valuable information is provided for targeted, label-free drug distribution studies and untargeted metabolomic datasets.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study
Endocrinology, 157(10), 3856–3872.
Contributors: S. Arambula n, S. Belcher n , A. Planchart n , S. Turner * & H. Patisaul n
MeSH headings : Administration, Oral; Animals; Animals, Newborn; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / toxicity; Female; Gene Expression / drug effects; Hippocampus / drug effects; Hippocampus / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Phenols / administration & dosage; Phenols / toxicity; Random Allocation; Rats; Rats, Sprague-Dawley; Sex Characteristics; Transcriptome / drug effects
TL;DR:
Preliminary data demonstrate prenatal BPA exposure, even at doses below the current no-observed-adverse-effect level, can alter gene expression in the developing brain.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2016 journal article
Examining ubiquitinated peptide enrichment efficiency through an epitope labeled protein
ANALYTICAL BIOCHEMISTRY, 512, 114–119.
author keywords: Ubiquitination; Gly-Gly enrichment; Enrichment efficiency
MeSH headings : Antibodies, Monoclonal, Murine-Derived / chemistry; Epitopes / chemistry; Muramidase / chemistry; Ubiquitinated Proteins / chemistry; Ubiquitination
TL;DR:
It is shown that when conjugated to a lysine containing protein, such as lysozyme, it can be applied as a standard protein to examine ubiquitinated peptide enrichment within a complex background.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Environmental Comparison of Biochar and Activated Carbon for Tertiary Wastewater Treatment
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 50(20), 11253–11262.
Contributors: K. Thompson*, K. Shimabuku *, J. Kearns n , D. Knappe n, R. Summers * & S. Cook *
TL;DR:
Overall, moderate capacity wood biochar is an environmentally superior alternative to coal-based PAC for micropollutant removal from wastewater, and its use can offset a wastewater facility's carbon footprint.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Advancing toxicology research using in vivo high throughput toxicology with small fish models
ALTEX - Alternatives to Animal Experimentation, 33(4), 435–452.
Contributors: A. Planchart n , C. Mattingly n , D. Allen *, P. Ceger *, W. Casey *, D. Hinton *, J. Kanungo *, S. Kullman n
author keywords: aquatic models; 21st century toxicology; alternatives
TL;DR:
The recommendations formulated by workshop participants to enhance the utility of small fish species in toxicology studies are summarized, as well as many of the advances in the field of toxicology that resulted from usingSmall freshwater fish species, including advances in developmental toxicology, cardiovascular toxicologists, neurotoxicology, and immunotoxicology are reviewed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database
Environmental Health Perspectives, 124(10), 1592–1599.
Contributors: C. Grondin n, A. Davis n, T. Wiegers n, B. King *, J. Wiegers n, D. Reif n , J. Hoppin n , C. Mattingly n
TL;DR:
Curation and integration of exposure data within the CTD provides researchers with new opportunities to correlate exposures with human health outcomes, to identify underlying potential molecular mechanisms, and to improve understanding about the exposome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2016 journal article
Using toxcast™ data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure
Environmental Health Perspectives, 124(7), 910–919.
Contributors: I. Shah *, R. Woodrow Setzer*, J. Jack n, K. Houck *, R. Judson *, T. Knudsen *, J. Liu *, M. Martin*
MeSH headings : Environmental Pollutants / toxicity; High-Throughput Screening Assays; Membrane Potential, Mitochondrial; Risk Assessment; Toxicity Tests / methods
TL;DR:
These findings show the utility of HCI data for reconstructing cell state trajectories and provide insight into the adaptation and resilience of in vitro cellular systems based on tipping points.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2016 review
Review of Automated Microinjection Systems for Single Cells in the Embryogenesis Stage
[Review of ]. IEEE-ASME TRANSACTIONS ON MECHATRONICS, 21(5), 2391–2404.
author keywords: Automation; biological cells; control system; mechatronics; reviews
TL;DR:
A comprehensive review of the major research technologies used in automated cell microin injection and of their individual subsystems concludes that research into automated microinjection systems will focus on reducing the scale of microinject systems and developing appropriate controllers.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes
METABOLOMICS, 12(11).
Contributors: C. Scott Chialvo *, R. Che n, D. Reif n , A. Motsinger-Reif n & L. Reed *
author keywords: Eigenvector metabolite analysis; Linkage analyses; Environment; Enrichment analyses
TL;DR:
Eigenvector Metabolite Analysis provides a simple method to identify correlations between metabolites, gene expression, and phenotypes, which can allow us to partition multivariate datasets into meaningful biological modules and identify under-studied metabolites and unannotated gene transcripts that may be central to important biological processes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Comparison of Field Measurements to Methane Emissions Models at a New Landfill
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 50(17), 9432–9441.
MeSH headings : Air Pollutants; Climate Change; Humans; Methane; Refuse Disposal; Solid Waste; Waste Disposal Facilities
TL;DR:
The results suggest the need for measurements at additional landfills to evaluate the accuracy of the tested models to young landfilling, and consistently overestimated annual methane emissions by a factor ranging from 4-31.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Can't take the heat: Temperature-enhanced toxicity in the mayfly Isonychia bicolor exposed to the neonicotinoid insecticide imidacloprid
AQUATIC TOXICOLOGY, 178, 49–57.
author keywords: Neonicotinoids; Imidacloprid; Aquatic invertebrates; Temperature; Toxicity; Physiology
MeSH headings : Animals; Aquatic Organisms / drug effects; Aquatic Organisms / metabolism; Behavior, Animal / drug effects; Dose-Response Relationship, Drug; Environmental Monitoring / methods; Ephemeroptera / drug effects; Ephemeroptera / metabolism; Hot Temperature; Imidazoles / toxicity; Insecticides / toxicity; Neonicotinoids; Nitro Compounds / toxicity; Toxicity Tests, Acute; Water Pollutants, Chemical / toxicity
TL;DR:
It is demonstrated that temperature is a powerful modulator of sublethal toxicity within a range of environmentally relevant temperatures, impacting both uptake rates and metabolic rates of I. bicolor and shows that temperature alters imidacloprid uptake across arange of species, highlighting the physiological variation present within aquatic invertebrate communities and the challenge associated with relying solely on surrogate species.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
ToxEvaluator: an integrated computational platform to aid the interpretation of toxicology study-related findings
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.
MeSH headings : Animals; Computational Biology / methods; Computer Simulation; Database Management Systems; Databases, Factual; Humans; Mice; Toxicogenetics / methods; User-Computer Interface
TL;DR:
ToxEvaluator was developed jointly by Pfizer and the Comparative Toxicogenomics Database as an in silico platform to facilitate interpretation of toxicity findings in light of prior knowledge and rapidly identified direct and indirect linkages between cerivastatin and myopathy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Systematic Evaluation of Industrial, Commercial, and Institutional Food Waste Management Strategies in the United States
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 50(16), 8444–8452.
MeSH headings : Food; Refuse Disposal; Soil; United States; Waste Disposal Facilities; Waste Management / methods
TL;DR:
Every scenario including WTE was preferable to every scenario including landfill, and Jurisdictions seeking to enact food waste disposal regulations should consider regional factors and material properties before duplicating existing statutes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 review
Salinized rivers: degraded systems or new habitats for salt-tolerant faunas?
[Review of ]. BIOLOGY LETTERS, 12(3).
author keywords: major ions; salinity; freshwater; novel ecosystems; osmoregulation; adaptation
MeSH headings : Animals; Biodiversity; Ecosystem; Insecta / physiology; Rivers / chemistry; Salinity
TL;DR:
A conceptual framework predicting how communities may change in salinizing rivers is outlined, envisioning that a relatively small number of taxa will be saline-tolerant and able to colonize salinized rivers, leading to depauperate communities in these environments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Release of Per- and Polyfluoroalkyl Substances (PFASs) from Carpet and Clothing in Model Anaerobic Landfill Reactors
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 50(10), 5024–5032.
MeSH headings : Clothing; Floors and Floorcoverings; Models, Theoretical; Waste Disposal Facilities; Water Pollutants, Chemical
TL;DR:
Monitoring of anaerobic model landfill reactors filled with carpet or clothing demonstrated that carpet and clothing are likely sources of PFASs in landfill leachate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 review
Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast (TM) High-Throughput Data
[Review of ]. ENVIRONMENTAL HEALTH PERSPECTIVES, 124(8), 1141–1154.
Contributors: S. Auerbach *, D. Filer*, D. Reif n , V. Walker *, A. Holloway *, J. Schlezinger *, S. Srinivasan *, D. Svoboda*
MeSH headings : Databases, Factual; Diabetes Mellitus / chemically induced; Diabetes Mellitus / epidemiology; Environment; Environmental Exposure / statistics & numerical data; Environmental Pollutants / standards; Environmental Pollutants / toxicity; High-Throughput Screening Assays; Humans; Obesity / chemically induced; Obesity / epidemiology; Outcome Assessment, Health Care; Risk Assessment; United States; United States Environmental Protection Agency
TL;DR:
The results of this screening-level analysis suggest that the spectrum of environmental chemicals to consider in research related to diabetes and obesity is much broader than indicated by research papers and reviews published in the peer-reviewed literature.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 review
Laying a Community-Based Foundation for Data-Driven Semantic Standards in Environmental Health Sciences
[Review of ]. ENVIRONMENTAL HEALTH PERSPECTIVES, 124(8), 1136–1140.
MeSH headings : Cooperative Behavior; Environmental Exposure / standards; Environmental Exposure / statistics & numerical data; Environmental Health / standards; Humans; Internet; National Institute of Environmental Health Sciences (U.S.); United States
TL;DR:
A foundation for enabling the development of community-based and data-driven semantic standards that will ultimately improve standardization, sharing, and interoperability of EHS information is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
BioCreative V CDR task corpus: a resource for chemical disease relation extraction
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.
MeSH headings : Computational Biology / methods; Data Mining / methods; Databases, Factual; Disease; Humans; Toxicogenetics / methods
TL;DR:
The BC5CDR corpus was successfully used for the BioCreative V challenge tasks and should serve as a valuable resource for the text-mining research community.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Assessing the state of the art in biomedical relation extraction: overview of the BioCreative V chemical-disease relation (CDR) task
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.
MeSH headings : Biomedical Research; Data Mining / methods; Databases, Factual; Disease; Humans; Statistics as Topic; Time Factors
TL;DR:
This task was found to be successful in engaging the text-mining research community, producing a large annotated corpus and improving the results of automatic disease recognition and CDR extraction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution
Proceedings of the National Academy of Sciences, 113(34), E5014–E5023.
author keywords: comparative genomics; proteasome and TAP evolution; major histocompatibility; MHC class I pathway; CG2 clonal zebrafish
MeSH headings : Animals; Antigen Presentation; Biological Evolution; Cloning, Organism; Cysteine Endopeptidases / classification; Cysteine Endopeptidases / genetics; Cysteine Endopeptidases / immunology; Genome; Haplotypes; High-Throughput Nucleotide Sequencing; Histocompatibility Antigens Class I / classification; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / immunology; Phylogeny; Proteasome Endopeptidase Complex / genetics; Proteasome Endopeptidase Complex / immunology; Protein Isoforms / classification; Protein Isoforms / genetics; Protein Isoforms / immunology; Transcriptome; Zebrafish / classification; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / classification; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR:
Comparison analysis shows that antigen processing gene diversity is far more extensive than previously realized, implying distinct immune functions and conserved roles in shaping MHC pathway evolution throughout vertebrates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
