Works Published in 2009
Displaying works 61 - 80 of 118 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 journal article
Sp2 Is a Maternally Inherited Transcription Factor Required for Embryonic Development
Journal of Biological Chemistry, 285(6), 4153–4164.
MeSH headings : Amino Acid Sequence; Animals; COS Cells; Chlorocebus aethiops; Chromosome Mapping; Embryo, Mammalian / embryology; Embryo, Mammalian / metabolism; Female; Gene Expression Regulation, Developmental; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Humans; In Situ Hybridization; Male; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Phylogeny; Promoter Regions, Genetic / genetics; RNA, Messenger, Stored / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sp2 Transcription Factor / classification; Sp2 Transcription Factor / genetics; Sp2 Transcription Factor / metabolism; Synteny; Transcription, Genetic; Zebrafish / embryology; Zebrafish / genetics; Zebrafish / growth & development; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
TL;DR:
The role(s) played by Sp2 in early metazoan development is addressed by cloned and characterized Sp2 from zebrafish, and the intron/exon organization and amino acid sequence of Sp2 is closely conserved with its mammalian orthologues.
(via Semantic Scholar)
www.jbc.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 21, 2019
2009 journal article
Developmental and tissue-specific expression of NITRs
Immunogenetics, 62(2), 117–122.
author keywords: Innate immunity; Lymphocytes; Natural killer receptors
MeSH headings : Animals; Embryo, Nonmammalian / metabolism; Female; Gene Expression Regulation, Developmental; Organ Specificity; Ovary / metabolism; Receptors, Immunologic / genetics; Receptors, Immunologic / immunology; Zebrafish / embryology; Zebrafish / genetics; Zebrafish / immunology; Zebrafish / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR:
The expression of multiple NITR genes in the zebrafish ovary and during embryogenesis is demonstrated and all 14 families of NITRs are shown to be expressed in the lymphocyte lineage, but not in the myeloid lineage, consistent with the hypothesis that N ITRs function as NKRs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, Crossref
Added: May 17, 2019
2009 journal article
Profiling Chemicals Based on Chronic Toxicity Results from the U.S. EPA ToxRef Database
Environ Health Perspect, 117(3), 392â399.
Contributors: M. Martin*, R. Judson *, D. Reif* , R. Kavlock* & D. Dix*
author keywords: cancer; chronic toxicity; pesticides; relational database; toxicity profile
MeSH headings : Computational Biology / methods; Databases, Factual; Ecotoxicology / methods; Environmental Pollutants / classification; Environmental Pollutants / toxicity; Pesticides / classification; Pesticides / toxicity; United States; United States Environmental Protection Agency
TL;DR:
The resulting toxicity profile classifications demonstrate the utility of structuring legacy toxicity information and facilitating the computation of these data within ToxRefDB for ToxCast and other applications.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2009 journal article
In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project
Environ Health Perspect, 118(4), 485â492.
author keywords: in vitro screening; liver proliferative lesions; liver tumors; pathways; ToxCast
MeSH headings : Animals; Cell Line; Cells, Cultured; Computer Simulation; Environmental Pollutants / toxicity; Humans; Rats; Toxicity Tests / methods; United States; United States Environmental Protection Agency
TL;DR:
A statistically significant inverse association between the number of pathways perturbed by a chemical at low in vitro concentrations and the lowest in vivo dose at which a chemical causes toxicity is found.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2009 journal article
A comparison of analytical methods for genetic association studies
Genet. Epidemiol., 33(8), 751â751.
Contributors: A. Motsinger-Reif n, D. Reif* , T. Fanelli* & M. Ritchie*
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 14, 2019
2009 journal article
Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination.
Genes and Immunity, 10(2), 112–119.
Contributors: D. Reif* , A. Motsinger-Reif n, B. McKinney *, M. Rock*, J. Crowe Jr. & J. Moore *
author keywords: smallpox; Random Forests; integrated analysis; genetic; proteomic; interactions
MeSH headings : Biomarkers / blood; Cytokines / blood; Cytokines / genetics; Decision Making, Computer-Assisted; Female; Humans; Inflammation / blood; Inflammation / chemically induced; Inflammation / genetics; Intercellular Adhesion Molecule-1 / blood; Intercellular Adhesion Molecule-1 / genetics; Male; Models, Biological; Polymorphism, Single Nucleotide; Proteomics / methods; Smallpox Vaccine / administration & dosage; Smallpox Vaccine / adverse effects; Vaccination
TL;DR:
This study built a comprehensive model of AE development that includes the cytokines intercellular adhesion molecule-1 (ICAM-1 or CD54), interleukin-10 (IL-10), and colony stimulating factor-3 (CSF-3 or G-CSF) and a genetic polymorphism in the cyokine gene interleUKin-4 (IL4).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 14, 2019
2009 journal article
Comparative microarray analysis and pulmonary changes in Brown Norway rats exposed to ovalbumin and concentrated air particulates.
Toxicological Sciences, 108(1), 207–221.
Contributors: B. Heidenfelder*, D. Reif* , J. Harkema*, E. Cohen Hubal *, E. Hudgens*, L. Bramble*, J. Wagner*, M. Morishita*
author keywords: ovalbumin; allergen; asthma; particulate matter; remodeling; inflammation; microarray
MeSH headings : Air Pollutants / toxicity; Allergens / administration & dosage; Allergens / immunology; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid / chemistry; Bronchoalveolar Lavage Fluid / immunology; Bronchopneumonia / metabolism; Bronchopneumonia / pathology; Gene Expression / drug effects; Inflammation / immunology; Lung / drug effects; Lung / immunology; Lung / metabolism; Lung / pathology; Male; Oligonucleotide Array Sequence Analysis; Ovalbumin / administration & dosage; Ovalbumin / immunology; Particulate Matter / administration & dosage; Particulate Matter / toxicity; Principal Component Analysis; Rats; Respiratory Hypersensitivity / metabolism; Respiratory Hypersensitivity / pathology; Respiratory Mucosa / drug effects; Respiratory Mucosa / immunology; Respiratory Mucosa / metabolism; Respiratory Mucosa / pathology
TL;DR:
The broad-based histopathology and functional genomic analyses demonstrate that exposure to CAPs exacerbates rodents with allergic inflammation induced by an allergen and suggests that asthmatics may be at increased risk for air pollution effects.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2009 journal article
Differences in PAH desorption and sediment organic matter composition between non-vegetated and recently vegetated fuel-oiled sediments
International Journal of Phytoremediation, 11, 463–478.
MeSH headings : Biodegradation, Environmental; Environmental Monitoring; Fuel Oils / analysis; Geologic Sediments / chemistry; Plants / metabolism; Polycyclic Aromatic Hydrocarbons / chemistry; Water Pollutants, Chemical / chemistry
TL;DR:
It is proposed that vegetation provides aliphatic, nonpolar carbon to IHC sediments that facilitates more rapid PAH desorption from bulk sediment and humin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2009 journal article
Population Density and Instream Habitat Suitability of the Endangered Cape Fear Shiner
TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY, 138(6), 1439–1457.
TL;DR:
The population density of Cape Fear shiners was estimated and whether physical habitat alterations were a likely cause of local extirpations and whether instream habitat limits the occurrence and density of this species was determined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
A Statewide Assessment of Mercury Dynamics in North Carolina Water Bodies and Fish
TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY, 138(6), 1328–1341.
TL;DR:
Using data collected by the North Carolina Department of Environment and Natural Resources, the U.S. Environmental Protection Agency, and others, a suite of biotic and abiotic factors and tissue mercury concentrations in fish from North Carolina water bodies were examined.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Morphogenesis of the Primitive Gut Tube Is Generated by Rho/ROCK/Myosin II-Mediated Endoderm Rearrangements
DEVELOPMENTAL DYNAMICS, 238(12), 3111–3125.
author keywords: gut; Xenopus; morphogenesis; endoderm, intercalation; elongation
MeSH headings : Animals; Animals, Genetically Modified; Body Patterning / genetics; Cell Polarity / genetics; Cell Shape / genetics; Embryo, Nonmammalian; Endoderm / cytology; Endoderm / embryology; Endoderm / metabolism; Gastrointestinal Diseases / congenital; Gastrointestinal Diseases / embryology; Gastrointestinal Tract / abnormalities; Gastrointestinal Tract / embryology; Gastrula / embryology; Gastrula / metabolism; Models, Biological; Morphogenesis / genetics; Nonmuscle Myosin Type IIB / genetics; Nonmuscle Myosin Type IIB / metabolism; Nonmuscle Myosin Type IIB / physiology; Signal Transduction / genetics; Xenopus / embryology; Xenopus / genetics; Xenopus / metabolism; rho-Associated Kinases / genetics; rho-Associated Kinases / metabolism; rho-Associated Kinases / physiology; rhoA GTP-Binding Protein / genetics; rhoA GTP-Binding Protein / metabolism; rhoA GTP-Binding Protein / physiology
TL;DR:
The results suggest that the cellular and molecular events driving tissue elongation in the PGT are mechanistically analogous to those that function during gastrulation, but occur within a novel cylindrical geometry to generate an epithelial‐lined tube.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Plasma Vitellogenin and Estradiol Concentrations in Adult Gulf Sturgeon from the Pascagoula River Drainage, Mississippi
TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY, 138(5), 1028–1035.
TL;DR:
The use of vitellogenin (Vtg) and estradiol (E2) were explored to identify the gender of adult Gulf sturgeon captured in the Pascagoula River drainage and to determine whether these substances were useful in identifying which females would be spawning in a given spring.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Inhaled carbon nanotubes reach the subpleural tissue in mice
NATURE NANOTECHNOLOGY, 4(11), 747–751.
MeSH headings : Aerosols / adverse effects; Animals; Immunity / drug effects; Inhalation Exposure / analysis; Male; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / adverse effects; Nanotubes, Carbon / ultrastructure; Pleura / drug effects; Pleura / immunology; Pleura / ultrastructure; Pulmonary Fibrosis / chemically induced
TL;DR:
It is shown that multi-walled carbon nanotubes reach the sub-pleura in mice after a single inhalation exposure of 30 mg/m3 for 6 hours and it is suggested that minimizing inhalation of nanot tubes during handling is prudent until further long term assessments are conducted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Extensive conservation of genomic imbalances in canine transmissible venereal tumors (CTVT) detected by microarray-based CGH analysis
CHROMOSOME RESEARCH, 17(7), 927–934.
author keywords: comparative genomic hybridization (CGH); canine; transmissible venereal tumor; chromosome; microarray
MeSH headings : Animals; Comparative Genomic Hybridization; DNA Copy Number Variations; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / transmission; Dogs; Female; Gene Expression Regulation, Neoplastic; Genome; Male; Oligonucleotide Array Sequence Analysis; Venereal Tumors, Veterinary / genetics; Venereal Tumors, Veterinary / immunology
TL;DR:
Characterization of a strategically selected panel of CTVT cases is presented using microarray-based comparative genomic hybridization analysis, showing for the first time that the tumor presents with an extensive range of non-random chromosome copy number aberrations that are distributed widely throughout the dog genome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 review
Regulation of female reproduction in mites: A unifying model for the Acari
[Review of ]. JOURNAL OF INSECT PHYSIOLOGY, 55(12), 1079–1090.
author keywords: Mites; Ticks; Acari; Vitellogenesis; Vitellogenin; Vitellin; Regulation; Juvenile hormone; Ecdysteroids
MeSH headings : Acari / physiology; Animals; Ecdysteroids / metabolism; Female; Juvenile Hormones / metabolism; Mites / physiology; Reproduction; Vitellogenesis; Vitellogenins / metabolism
TL;DR:
A new working hypothesis is proposed, i.e., that ecdysteroids and not the JHs regulate vitellogenesis in the Acari including both ticks and mites.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Microarray-based cytogenetic profiling reveals recurrent and subtype-associated genomic copy number aberrations in feline sarcomas
CHROMOSOME RESEARCH, 17(8), 987–1000.
author keywords: microarray; comparative genomic hybridization (CGH); feline; sarcoma; chromosome
MeSH headings : Animals; Cat Diseases / diagnosis; Cats; Cytogenetic Analysis; DNA Copy Number Variations; Gene Dosage; Gene Expression Profiling; Injections / adverse effects; Oligonucleotide Array Sequence Analysis; Sarcoma / diagnosis; Sarcoma / genetics; Sarcoma / veterinary
TL;DR:
Construction of a genomic microarray platform for detection of recurrent CNAs in feline tumors through cytogenetic assignment of 210 large-insert DNA clones selected at intervals of ∼15 Mb from the feline genome sequence assembly is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Effect of Free Chlorine Application on Microbial Quality of Drinking Water in Chloraminated Distribution Systems
Journal AWWA, 101(10), 60–70.
Contributors: E. Rosenfeldt, C. Baeza & D. Knappe
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2009 article
Water-flow variation and pharmacoepidemiology of tetracycline hydrochloride administration via drinking water in swine finishing farms
Dorr, P. M., Nemechek, M. S., Scheidt, A. B., Baynes, R. E., Gebreyes, W. A., & Almond, G. W. (2009, August 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 235, pp. 299–304.
MeSH headings : Animal Husbandry / instrumentation; Animal Husbandry / methods; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Chromatography, High Pressure Liquid / veterinary; Cohort Studies; Cross-Sectional Studies; Drinking / physiology; Drinking Behavior; Swine / blood; Swine / physiology; Tetracycline / administration & dosage; Tetracycline / blood; Water / chemistry
TL;DR:
Medication of pigs with tetracycline through water as performed in this study had questionable therapeutic value and many factors affected drinker flow rates and therefore the amount of medication pigs might have received.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 review
Transport and release of chemicals from plastics to the environment and to wildlife
[Review of ]. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 364(1526), 2027–2045.
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Selenium Bioaccumulation and Maternal Transfer in the Mayfly Centroptilum triangulifer in a Life-Cycle, Periphyton-Biofilm Trophic Assay
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 43(20), 7952–7957.
MeSH headings : Animals; Biofilms; Eukaryota / metabolism; Female; Food Chain; Insecta / growth & development; Insecta / metabolism; Larva / metabolism; Oviparity / drug effects; Ovum / metabolism; Selenium / metabolism; Selenium / toxicity; Selenium Radioisotopes
TL;DR:
It is suggested that at environmentally feasible dietary Se concentrations insects are potentially affected by Se exposure, and that the current presumption that insects are simply conduits of Se to higher trophic levels is inaccurate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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