Works Published in 2012
Displaying works 21 - 40 of 101 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 conference paper
Gait planning and double support phase model for functional electrical stimulation-based walking
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 1904–1907.
Contributors: N. Sharma* & R. Stein*
MeSH headings : Electric Stimulation; Gait / physiology; Humans; Leg / physiology; Models, Theoretical; Thigh / physiology; Torque; Walking / physiology
TL;DR:
Lower limb segment angle trajectories are computed from simple mathematical models developed to represent functional electrical stimulation (FES) and a novel brace based walking to design walking trajectories that minimize muscle activations and arm reaction forces generated from the walker.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(OpenAlex)
Source: ORCID
Added: August 12, 2021
2012 journal article
Closed-loop neural network-based NMES control for human limb tracking
IEEE Transactions on Control Systems Technology, 20(3), 712–725.
Contributors: N. Sharma* , C. Gregory*, M. Johnson * & W. Dixon *
author keywords: Asymptotic stability; closed-loop control of functional electrical stimulation (FES); neural networks (NNs); neuromuscular electrical stimulation (NMES); non-isometric contractions; nonlinear control; robust integral of the sign of the error (RISE)-based feedback
TL;DR:
Efforts in this paper focus on the use of a NN feedforward controller that is augmented with a continuous robust feedback term to yield an asymptotic result (in lieu of typical uniformly ultimately bounded stability).
(via Semantic Scholar)
citeseerx.ist.psu.edu (repository)
Source: ORCID
Added: August 12, 2021
2012 conference paper
A predictor-based compensation for electromechanical delay during neuromuscular electrical stimulation-II
Proceedings of the American Control Conference, 5604–5609. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869406024&partnerID=MN8TOARS
Contributors: N. Sharma
Source: ORCID
Added: August 12, 2021
2012 journal article
Potential of healing a transected anterior cruciate ligament with genetically modified extracellular matrix bioscaffolds in a goat model
Knee Surgery, Sports Traumatology, Arthroscopy, 20(7), 1357–1365.
MeSH headings : Animals; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction / methods; Biomechanical Phenomena; Extracellular Matrix; Galactosyltransferases / deficiency; Goats; Guided Tissue Regeneration; Hydrogel, Polyethylene Glycol Dimethacrylate; Materials Testing; Models, Animal; Prostheses and Implants; Swine; Tissue Engineering; Tissue Scaffolds
TL;DR:
The application of an ECM bioscaffold and hydrogel was found to accelerate the healing of a transected ACL following suture repair in the goat model with limited tissue hypertrophy and improvement in some of its biomechanical properties.
(via Semantic Scholar)
Source: Crossref
Added: February 7, 2021
2012 journal article
Macrophages modulate the viability and growth of human mesenchymal stem cells
Journal of Cellular Biochemistry, 114(1), 220–229.
author keywords: MESENCHYMAL STEM CELLS; MACROPHAGES; INFLAMMATION
MeSH headings : Cell Communication; Cell Line; Cell Proliferation / drug effects; Cell Survival / drug effects; Coculture Techniques; Cytokines / pharmacology; Humans; Inflammation / metabolism; Inflammation / pathology; Lipopolysaccharides / pharmacology; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Models, Biological; Vascular Endothelial Growth Factor A / pharmacology
TL;DR:
Data imply that an anti‐inflammatory (M2) environment is more accommodating to the therapeutic hMSCs than a pro‐ inflammatory (M1) environment at specific concentrations.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2012 journal article
Hydrodynamic Shaping, Polymerization, and Subsequent Modification of Thiol Click Fibers
ACS Applied Materials & Interfaces, 5(1), 114–119.
author keywords: click chemistry; hydrodynamic focusing; microfibers; microfluidics; thiol-ene; thiol-yne
TL;DR:
A proof-of-principle experiment demonstrated that biotin attached to thiol groups on the fiber surface could specifically bind a fluorescent protein.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2012 journal article
Defect mediated photocatalytic decomposition of 4-chlorophenol on epitaxial rutile thin films under visible and UV illumination
Journal of Physics: Condensed Matter, 24(39), 395005.
MeSH headings : Catalysis; Chlorophenols / chemistry; Oxygen / chemistry; Photochemical Processes; Pressure; Titanium / chemistry; Ultraviolet Rays; Vacuum; X-Ray Diffraction
TL;DR:
It is shown that pure rutile TiO(2) can be photo-responsive even under low energy visible light after annealing in vacuum where it is envisaged that the point defects, i.e. oxygen vacancies and titanium interstitials, serve an important role.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Crossref
Added: January 14, 2021
2012 journal article
Recent Developments in Electronic, Functional, and Biological Thin Films
JOM, 64(4), 505–505.
Source: Crossref
Added: January 14, 2021
2012 journal article
Domain epitaxy in TiO2/α-Al2O3 thin film heterostructures with Ti2O3 transient layer
Applied Physics Letters, 100(25), 251606.
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
Source: Crossref
Added: January 14, 2021
2012 journal article
Ultrananocrystalline Diamond-Coated Microporous Silicon Nitride Membranes for Medical Implant Applications
JOM, 64(4), 520–525.
TL;DR:
The results show that the UNCD coating did not significantly alter the viability of human epidermal keratinocytes, indicating potential use of this material for improving skin sealing around percutaneous implants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 14, 2021
2012 journal article
Multiplexed and switchable release of distinct fluids from microneedle platforms via conducting polymer nanoactuators for potential drug delivery
Sensors and Actuators B: Chemical, 161(1), 1018–1024.
author keywords: Microneedle array; Conducting polymer; Electrochemically switchable nanoactuator; Drug delivery
TL;DR:
A microneedle-based multiplexed drug delivery actuator that enables the controlled delivery of multiple therapeutic agents and indicates the potential to counteract diverse biomedical conditions is reported on.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: January 14, 2021
2012 journal article
Structural Basis of Efficient Electron Transport between Photosynthetic Membrane Proteins and Plastocyanin in Spinach Revealed Using Nuclear Magnetic Resonance
Plant Cell, 24(10), 4173–4186.
Contributors: T. Ueda *, N. Nomoto*, M. Koga*, H. Ogasa*, Y. Ogawa*, M. Matsumoto*, P. Stampoulis*, K. Sode* , H. Terasawa*, I. Shimada *
MeSH headings : Cytochrome b6f Complex / metabolism; Electron Transport; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Membrane Proteins / chemistry; Membrane Proteins / metabolism; Molecular Sequence Data; Photosynthesis; Photosystem I Protein Complex / metabolism; Plastocyanin / chemistry; Plastocyanin / metabolism; Spinacia oleracea / metabolism
TL;DR:
This work investigates the residues of plastocyanin in close proximity to photosystem I and cytochrome b6f, in both the thylakoid vesicle–embedded and solubilized states to demonstrate the transient characteristics of the interactions on the acidic patch facilitate the rapid association and dissociation of Pc.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: October 9, 2020
2012 journal article
Selection of DNA Aptamers That Recognize alpha-Synuclein Oligomers Using a Competitive Screening Method
Analytical Chemistry, 84(13), 5542–5547.
Contributors: K. Tsukakoshi *, K. Abe *, K. Sode* & K. Ikebukuro *
MeSH headings : Alzheimer Disease / metabolism; Amyloid / chemistry; Amyloid / metabolism; Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Base Sequence; Binding, Competitive; Gene Library; Humans; Parkinson Disease / metabolism; Protein Binding; Protein Structure, Secondary; SELEX Aptamer Technique; alpha-Synuclein / chemistry; alpha-Synuclein / metabolism
TL;DR:
The results of this study support the hypothesis that amyloid oligomers share a common structure and may serve as powerful analytical tools for the design and development of drugs and diagnostic tests for neurodegenerative diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: October 9, 2020
2012 journal article
Nitrous Oxide Sensing using Oxygen-Insensitive Direct-Electron-Transfer-Type Nitrous Oxide Reductase
Electrochemistry, 80(5), 371–374.
Contributors: W. Tsugawa *, H. Shimizu*, M. Tatara*, Y. Ueno *, K. Kojima* & K. Sode*
author keywords: Nitrous Oxide; Nitrous Oxide Reductase; Direct Electron Transfer; Cytochrome c
Source: ORCID
Added: October 9, 2020
2012 journal article
Electrochemical SNP Detection Using Glucose Dehydrogenase
Electrochemistry, 80(5), 345–347.
Contributors: K. Abe *, C. Kiyohara*, Y. Saito *, K. Sode* & K. Ikebukuro *
author keywords: Single Nucleotide Polymorphism; Glucose Dehydrogenase; Single Base Extension
TL;DR:
An electrochemical detection system of an SNP of peroxisome proliferator-activated receptor γ2 (PPARγ2) (C34G) using glucose dehydrogenase (GDH) based on a single base extension method based on amperometric sensing system is constructed.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2012 journal article
Detection of Pathogenic Bacteria by Using Zinc Finger Protein Fused with Firefly Luciferase
Analytical Chemistry, 84(18), 8028–8032.
Contributors: K. Abe *, T. Kumagai *, C. Takahashi *, A. Kezuka*, Y. Murakami*, Y. Osawa*, H. Motoki*, T. Matsuo*
MeSH headings : Binding Sites; DNA, Bacterial / analysis; Early Growth Response Protein 1 / genetics; Early Growth Response Protein 1 / metabolism; Escherichia coli / genetics; Escherichia coli / isolation & purification; Legionella pneumophila / genetics; Legionella pneumophila / isolation & purification; Luciferases, Firefly / genetics; Luciferases, Firefly / metabolism; Polymerase Chain Reaction; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Sp1 Transcription Factor / genetics; Sp1 Transcription Factor / metabolism; Zinc Fingers / genetics
TL;DR:
A novel bacterial genome detection system using zinc finger protein fused with firefly luciferase (ZF-luciferase), which succeeded in the detection of 10 copies of the genome of Legionella pneumophila and Escherichia coli O157.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2012 journal article
Construction of Mutant Glucose Oxidases with Increased Dye-Mediated Dehydrogenase Activity
International Journal of Molecular Sciences, 13(11), 14149–14157.
Contributors: Y. Horaguchi*, S. Saito*, K. Kojima*, W. Tsugawa *, S. Ferri* & K. Sode*
author keywords: glucose oxidase; glucose dehydrogenase; FAD; oxygen; site directed mutagenesis
MeSH headings : Amino Acid Substitution; Coloring Agents / chemistry; Coloring Agents / metabolism; Glucose Oxidase / chemistry; Glucose Oxidase / genetics; Glucose Oxidase / metabolism; Kinetics; Models, Molecular; Molecular Conformation; Mutation; Oxidation-Reduction; Oxidoreductases / chemistry; Oxidoreductases / metabolism; Oxygen / chemistry; Oxygen / metabolism; Substrate Specificity
TL;DR:
Results indicate that alteration of the dehydrogenase/oxidase activity ratio of GOxs is possible by introducing a mutation into the putative functional residues responsible for oxidative half reaction with oxygen of these enzymes, resulting in a further increased dehydrogen enzyme activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: October 9, 2020
2012 journal article
Construction of engineered fructosyl peptidyl oxidase for enzyme sensor applications under normal atmospheric conditions
Biotechnology Letters, 34(3), 491–497.
Contributors: S. Kim*, E. Nibe*, W. Tsugawa *, K. Kojima*, S. Ferri* & K. Sode*
author keywords: Biosensor; Dehydrogenase; Diabetes; Fructosyl peptidyl oxidase (FPOX); Glycated protein; HbA1c
MeSH headings : Amino Acid Oxidoreductases / genetics; Amino Acid Oxidoreductases / metabolism; Ascomycota / enzymology; Biosensing Techniques / methods; Glycated Hemoglobin / analysis; Recombinant Proteins / genetics; Recombinant Proteins / metabolism
TL;DR:
Improvement of dye-mediated dehydrogenase activity of FPOXs and its application to enzyme electrode construction were undertaken to produce an enzyme electrode for the measurement of fructosyl-αN-valyl-histidine (f-αVal-His), the protease-digested product of HbA1c.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: October 9, 2020
2012 journal article
Biomolecular Engineering of Biosensing Molecules - The Challenges in Creating Sensing Molecules for Glycated Protein Biosensing
Electrochemistry, 80(5), 293–298.
Contributors: S. Ferri* & K. Sode*
author keywords: Biomolecular Engineering; Biosensing; Glycated Proteins; Fructosyl Peptide Oxidase
TL;DR:
Glycated protein sensing is one of the most emergent and focused on technology in the field of diabetes diagnosis and the recent advances in the development of fructosyl amino acid/fructo peptide oxidases are focused on to acknowledge the rewards of the current advanced biomolecular engineering technology.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2012 journal article
BioLC-Oscillator: A Self-Powered Wireless Glucose-Sensing System with the Glucose Dependent Resonance Frequency
Electrochemistry, 80(5), 367–370.
Contributors: T. Hanashi*, T. Yamazaki *, W. Tsugawa *, K. Ikebukuro * & K. Sode*
author keywords: BioCapacitor; Continuous Glucose Monitoring; Glucose Dehydrogenase; Wireless Sensing System
TL;DR:
This study succeeded in constructing a stand-alone, self-powered, wireless glucose sensing system called the BioLC-Oscillator by using a radio transmitter in which the radio wave resonance frequency changes according to glucose concentration within the range from 0.86 to 10.1mM, which covers from the hypoglycemic range to a part of the hyperglycemic range.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: October 9, 2020
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