Bioinformatics

Interdisciplinary Programs

Works Published in 2021

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

A Neuroprotective Locus Modulates Ischemic Stroke Infarction Independent of Collateral Vessel Anatomy

FRONTIERS IN NEUROSCIENCE.

By: H. Lee, S. Wetzel-Strong, D. Aylor & D. Marchuk

Source: Web Of Science
Added: August 30, 2021

2021 article

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances

Kirkwood, K. I., Fleming, J., Nguyen, H., Reif, D. M., Baker, E. S., & Belcher, S. M. (2021, August 26). (Vol. 8). Vol. 8.

By: K. Kirkwood, J. Fleming, H. Nguyen, D. Reif, E. Baker & S. Belcher

Source: ORCID
Added: August 27, 2021

2021 journal article

High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs

PLOS Genetics, 17(8), e1009732.

By: F. Akhtari, A. Green, G. Small, T. Havener, J. House, K. Roell, D. Reif, H. McLeod, T. Wiltshire, A. Motsinger-Reif

Ed(s): F. Vazquez

Source: ORCID
Added: August 27, 2021

2021 article

Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies

McDonough, C. W., Warren, H. R., Jack, J. R., Motsinger-Reif, A. A., Armstrong, N. D., Bis, J. C., … Cooper-DeHoff, R. M. (2021, August 15). CLINICAL PHARMACOLOGY & THERAPEUTICS.

By: C. McDonough, H. Warren, J. Jack, A. Motsinger-Reif, N. Armstrong, J. Bis, J. House, S. Singh ...

Source: Web Of Science
Added: August 23, 2021

2021 article

A critical overview of computational approaches employed for COVID-19 drug discovery

Muratov, E. N., Amaro, R., Andrade, C. H., Brown, N., Ekins, S., Fourches, D., … Tropsha, A. (2021, July 2). CHEMICAL SOCIETY REVIEWS.

By: E. Muratov, R. Amaro, C. Andrade, N. Brown, S. Ekins, D. Fourches, O. Isayev, D. Kozakov ...

Source: Web Of Science
Added: July 26, 2021

2021 journal article

Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry

ENERGY & FUELS.

By: A. Roman-Hubers, A. Cordova, N. Aly, T. McDonald, D. Lloyd, F. Wright, E. Baker, W. Chiu, I. Rusyn

Source: Web Of Science
Added: July 26, 2021

2021 journal article

Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments

ANALYTICAL CHEMISTRY, 6.

Sources: Web Of Science, ORCID
Added: July 19, 2021

2021 journal article

Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology

PLOS COMPUTATIONAL BIOLOGY, 17(7), e1009135.

By: A. Green, M. Mohlenkamp, J. Das, M. Chaudhari, L. Truong, R. Tanguay, D. Reif

Ed(s): V. Hatzimanikatis

Sources: ORCID, Web Of Science
Added: July 5, 2021

2021 journal article

CATMoS: Collaborative Acute Toxicity Modeling Suite

ENVIRONMENTAL HEALTH PERSPECTIVES.

By: K. Mansouri, A. Karmaus, J. Fitzpatrick, G. Patlewicz, P. Pradeep, D. Alberga, N. Alepee, T. Allen ...

Source: Web Of Science
Added: June 28, 2021

2021 journal article

Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification

Frontiers in Toxicology, 3.

By: P. Thunga, L. Truong, R. Tanguay & D. Reif

Source: ORCID
Added: June 22, 2021

2021 journal article

Knockoff boosted tree for model-free variable selection

BIOINFORMATICS.

Source: Web Of Science
Added: June 21, 2021

2021 journal article

Toward genetic modification of plant-parasitic nematodes: delivery of macromolecules to adults and expression of exogenous mRNA in second stage juveniles

G3-GENES GENOMES GENETICS, 2.

By: O. Kranse, H. Beasley, S. Adams, A. Pires-daSilva, C. Bell, C. Lilley, P. Urwin, D. Bird ...

Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 article

Extending the lymphoblastoid cell line model for drug combination pharmacogenomics

Green, A. J., Anchang, B., Akhtari, F. S., Reif, D. M., & Motsinger-Reif, A. (2021, May 28). PHARMACOGENOMICS, Vol. 22, pp. 543–551.

Sources: Web Of Science, ORCID
Added: May 29, 2021

2021 article

Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks

JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY.

By: N. Aly, G. Casillas, Y. Luo, T. McDonald, T. Wade, R. Zhu, G. Newman, D. Lloyd ...

Source: Web Of Science
Added: May 24, 2021

2021 journal article

SMILES Pair Encoding: A Data-Driven Substructure Tokenization Algorithm for Deep Learning

JOURNAL OF CHEMICAL INFORMATION AND MODELING, 61(4), 1560–1569.

By: X. Li & D. Fourches

Source: Web Of Science
Added: May 24, 2021

2021 journal article

Race and smoking status associated with paclitaxel drug response in patient-derived lymphoblastoid cell lines

PHARMACOGENETICS AND GENOMICS, 31(2), 48–52.

By: F. Akhtari, T. Havener, D. Hertz, J. Ash, A. Larson, L. Carey, H. McLeod, A. Motsinger-Reif

Source: Web Of Science
Added: May 10, 2021

2021 journal article

The VKORC1 ER-luminal loop mutation (Leu76Pro) leads to a significant resistance to warfarin in black rats (Rattus rattus)

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 173.

By: K. Takeda, Y. Ikenaka, D. Fourches, K. Tanaka, S. Nakayama, D. Triki, X. Li, M. Igarashi, T. Tanikawa, M. Ishizuka

Source: Web Of Science
Added: April 26, 2021

2021 review

Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions

[Review of ]. TOXICS, 9(4).

By: D. Wallis, L. Truong, J. La Du, R. Tanguay & D. Reif

Sources: ORCID, Web Of Science
Added: April 7, 2021

2021 journal article

Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes

FOOD AND CHEMICAL TOXICOLOGY, 149.

By: Y. Luo, Z. Chen, A. Blanchette, Y. Zhou, F. Wright, E. Baker, W. Chiu, I. Rusyn

Source: Web Of Science
Added: April 5, 2021

2021 personal communication

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning

Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y.-H., Wright, F. A., … Reif, D. M. (2021, January).

By: S. Marvel, J. House, M. Wheeler, K. Song, Y. Zhou, F. Wright, W. Chiu, I. Rusyn, A. Motsinger-Reif, D. Reif

Sources: Web Of Science, ORCID
Added: March 22, 2021