Works Published in 2024
Displaying all 7 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2024 article
Two-Stage Machine Learning-Based Approach to Predict Points of Departure for Human Noncancer and Developmental/Reproductive Effects
Kvasnicka, J., Aurisano, N., Borries, K., Lu, E.-H., Fantke, P., Jolliet, O., … Chiu, W. A. (2024, May 2). ENVIRONMENTAL SCIENCE & TECHNOLOGY.
author keywords: QSAR model; machine learning; toxicity prediction; chemical risk assessment; high-throughput screening; life cycle impact assessment (LCIA)
doi.org (publisher)
Source: Web Of Science
Added: June 17, 2024
2024 article
Protein-adaptive differential scanning fluorimetry using conformationally responsive dyes
Wu, T., Yu, J. C., Suresh, A., Gale-Day, Z. J., Alteen, M. G., Woo, A. S., … Gestwicki, J. E. (2024, May 14). NATURE BIOTECHNOLOGY.
Source: Web Of Science
Added: June 3, 2024
2024 journal article
Hazard and risk characterization of 56 structurally diverse PFAS using a targeted battery of broad coverage assays using six human cell types
TOXICOLOGY, 503.
author keywords: PFAS; In vitro; Grouping; Risk characterization; Margin of exposure
Source: Web Of Science
Added: May 7, 2024
2024 journal article
Control of false discoveries in grouped hypothesis testing for eQTL data
BMC BIOINFORMATICS, 25(1).
author keywords: eQTL; Grouped hypothesis testing; False discovery rate; Empirical Bayes
Source: Web Of Science
Added: April 22, 2024
2024 article
Genetic variation in severe cystic fibrosis liver disease is associated with novel mechanisms for disease pathogenesis
Stonebraker, J., Pace, R., Gallins, P., Dang, H., Aksit, M., Faino, A., … Knowles, M. (2024, March 27). HEPATOLOGY.
author keywords: MAIT cells; whole genome sequencing; GWAS; TWAS; CFLD
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: April 15, 2024
2024 journal article
Investigating mouse hepatic lipidome dysregulation following exposure to emerging per- and polyfluoroalkyl substances (PFAS)
Chemosphere.
TL;DR:
Results provide valuable insight into the liver bioaccumulation and molecular mechanisms of GenX- and NBP2-induced hepatotoxicity and various specific fatty acyls were greatly impacted, indicating alteration of inflammation, oxidative stress, and cellular signaling processes due to emerging PFAS exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: March 15, 2024
2024 journal article
Guided optimization of ToxPi model weights using a Semi-Automated approach
COMPUTATIONAL TOXICOLOGY, 29.
author keywords: Machine learning; Feature weighting; Exposure assessment; Chemical toxicity; Ordinal regression; Genetic algorithm
Sources: Web Of Science, NC State University Libraries
Added: January 16, 2024
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