Bioinformatics

MagicalRsq: Machine-learning-based genotype imputation quality calibration

AMERICAN JOURNAL OF HUMAN GENETICS, 109(11), 1986–1997.

Bayesian Matrix Completion for Hypothesis Testing

Jin, B., Dunson, D., Herring, A., Engel, S., Reif, D., & Rager, J. (2022, December 16).

Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure

TOXICS, 10(12).

Assessing the Nucleotide-Level Impact of Spaceflight Stress using RNA-Sequencing Data

Knight, M. S., Doherty, C. J., & Nielsen, D. M. (2022, December 2).

Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies

AMERICAN JOURNAL OF HUMAN GENETICS, 109(9), 1638–1652.

Pleiotropic modifiers of age-related diabetes and neonatal intestinal obstruction in cystic fibrosis

AMERICAN JOURNAL OF HUMAN GENETICS, 109(10), 1894–1908.

A cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes

AMERICAN JOURNAL OF HUMAN GENETICS, 109(10), 1814–1827.

TCDD alters essential transcriptional regulators of osteogenic differentiation in multipotent mesenchymal stem cells

Watson, A. L. T. D., Carmona Baez, A., Jima, D., Reif, D., Ding, J., Roberts, R., & Kullman, S. W. (2022, November 12). TOXICOLOGICAL SCIENCES, Vol. 11.

Comparative Toxicogenomics Database (CTD): update 2023

Davis, A. P., Wiegers, T. C., Johnson, R. J., Sciaky, D., Wiegers, J., & Mattingly, C. J. (2022, September 28). NUCLEIC ACIDS RESEARCH.

Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke

ENVIRONMENT INTERNATIONAL, 167.

Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(18).

Impacts of Gestational FireMaster 550 (FM 550) Exposure on the Neonatal Cortex are Sex Specific and Largely Attributable to the Organophosphate Esters

Witchey, S. K., Doyle, M. G., Fredenburg, J. D., St Armour, G., Horman, B., Odenkirk, M. T., … Patisaul, H. B. (2022, September 8). NEUROENDOCRINOLOGY.

A resource for integrated genomic analysis of the human liver

SCIENTIFIC REPORTS, 12(1).

A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures

TOXICS, 10(8).

Grouping of UVCB Substances with Dose-Response Transcriptomics Data from Human Cell-Based Assays

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 39(3), 388–404.

Model systems and organisms for addressing inter- and intra-species variability in risk assessment

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 132.

Correlation Analysis of Variables From the Atherosclerosis Risk in Communities Study

FRONTIERS IN PHARMACOLOGY, 13.

Confidence bands and hypothesis tests for hit enrichment curves

JOURNAL OF CHEMINFORMATICS, 14(1).

TwinEQTL: ultrafast and powerful association analysis for eQTL and GWAS in twin studies

Xia, K., Shabalin, A. A., Yin, Z., Chung, W., Sullivan, P. F., Wright, F. A., … Zou, F. (2022, June 11). GENETICS.

Genomic map of candidate human imprint control regions: the imprintome

Jima, D. D., Skaar, D. A., Planchart, A., Motsinger-Reif, A., Cevik, S. E., Park, S. S., … Hoyo, C. (2022, June 25). EPIGENETICS.