Works Published in 2015

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Displaying works 21 - 40 of 45 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Parents' and Children's Acceptance of Skim Chocolate Milks Sweetened by Monk Fruit and Stevia Leaf Extracts

JOURNAL OF FOOD SCIENCE, 80(5), S1083–S1092.

By: X. Li n, K. Lopetcharat & M. Drake n

author keywords: chocolate milk; natural nonnutritive sweetener; priming; power function; sugar reduction
MeSH headings : Adult; Animals; Cacao; Child; Choice Behavior; Consumer Behavior; Cucurbitaceae; Dietary Sucrose; Female; Food Labeling; Food Preferences; Fruit; Humans; Male; Milk; Parents; Perception; Plant Leaves; Plant Preparations; Stevia; Sweetening Agents; Taste; Young Adult
TL;DR: Traditional parents preferred sucrose sweetened SCM, and label conscious parents preferred SCM with natural nonnutritive sweeteners, which was acceptable by young adults and children. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Microbial Ecology of Watery Kimchi

JOURNAL OF FOOD SCIENCE, 80(5), M1031–M1038.

By: K. Kyung*, E. Medina Pradas, S. Kim*, Y. Lee*, K. Kim*, J. Choi*, J. Cho*, C. Chung*, R. Barrangou n, F. Breidt n

author keywords: high-throughput sequencing; microbial ecology; watery kimchi
MeSH headings : DNA, Bacterial / chemistry; DNA, Bacterial / classification; DNA, Bacterial / isolation & purification; DNA, Ribosomal / chemistry; Enterobacteriaceae / classification; Enterobacteriaceae / genetics; Enterobacteriaceae / isolation & purification; Fermentation; Food Microbiology; Lactobacillus / classification; Proteobacteria / classification; Proteobacteria / genetics; Proteobacteria / isolation & purification; RNA, Ribosomal, 16S / genetics; Raphanus / microbiology; Sequence Analysis, DNA; Temperature; Vegetables / microbiology
TL;DR: Differences in biochemistry and microbial ecology that can result from preparation method and fermentation conditions of the kimchi may impact safety and quality and quality (homolactic fermentation can be undesirable, if too much acid is produced) of the product. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 review

Harnessing CRISPR-Cas systems for bacterial genome editing

[Review of ]. TRENDS IN MICROBIOLOGY, 23(4), 225–232.

By: K. Selle n & R. Barrangou n

author keywords: genome editing; CRISPR-Cas; Cas9
MeSH headings : Bacteria / genetics; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats; DNA Repair; Genetic Engineering / methods; Genome, Bacterial; Homeostasis / genetics; Mutation; Phenotype
TL;DR: This review summarizes recent progress in bacterial genome editing and identifies fundamental genetic and phenotypic outcomes of CRISPR targeting in bacteria, in the context of tool development, genome homeostasis, and DNA repair. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 article

Genetic Mechanisms of Prebiotic Oligosaccharide Metabolism in Probiotic Microbes

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 6, Vol. 6, pp. 137–156.

author keywords: Lactobacillus; Bifidobacterium; fructooligosaccharide; galactooligosaccharide; prebiotic; probiotic
MeSH headings : Bifidobacterium / metabolism; Lactobacillus / metabolism; Oligosaccharides / metabolism; Prebiotics; Probiotics
TL;DR: This review highlights recent findings on the genetic mechanisms involved in the utilization of prebiotic fructooligosaccharides, β-galactooligOSaccharide, human milk oligosac charides, and other prebiotics candidates by these probiotic microbes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 review

Examining Extrinsic Factors that Influence Product Acceptance: A Review

[Review of ]. JOURNAL OF FOOD SCIENCE, 80(5), R901–R909.

author keywords: brand; decision making; drivers of liking; emotions; perceived satiety; willingness-to-pay
MeSH headings : Commerce; Consumer Behavior; Diet / economics; Diet / psychology; Emotions; Food Industry; Food Labeling; Food Preferences; Food Quality; Humans; Satiation
TL;DR: These 4 key extrinsic factors that affect DOL are the perceived satiety, brand and labeling, price, and the emotional impact to decision making, which should be considered in conjunction with sensory attribute perception to gain a holistic understanding of product acceptance. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Decolorization of Cheddar cheese whey by activated carbon

JOURNAL OF DAIRY SCIENCE, 98(5), 2982–2991.

author keywords: activated carbon; norbixin (annatto) removal; Cheddar cheese whey; bleaching; volatile analysis
MeSH headings : Animals; Bleaching Agents / chemistry; Carbon / analysis; Carotenoids / chemistry; Cattle; Cheese / analysis; Color; Food Handling; Gas Chromatography-Mass Spectrometry; Hot Temperature; Hydrogen Peroxide / chemistry; Milk Proteins / analysis; Taste; Whey / chemistry; Whey Proteins
TL;DR: The color and residual norbixin content of Cheddar whey were reduced by a higher level of activated carbon at a higher temperature between 25 and 55°C and a longer time, and the lowered temperature in activated-carbon treatments had less effect on protein structure as investigated for fluorescence spectroscopy and volatile compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Charge related astringency of chitosans

FOOD HYDROCOLLOIDS, 48, 174–178.

By: P. Luck n, K. Varum* & E. Foegeding n

author keywords: Astringency; Chitosan; Saliva; Proline-rich proteins; Mucins
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Characterization and evolution of Salmonella CRISPR-Cas systems

MICROBIOLOGY-SGM, 161, 374–386.

TL;DR: Salmonella CRISPR-Cas systems are no longer immunogenic; rather, their impressive conservation indicates they may have an alternative function in Salmonella, and high level of conservation across divergent serovars shows that the genetic integrity of these inactive loci is maintained over time, contrasting with the canonical view that inactive CRISpr loci degenerate over time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

CRISPR-based screening of genomic island excision events in bacteria

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(26), 8076–8081.

author keywords: CRISPR; lactic acid bacteria; transposons; IS-elements; Cas9
MeSH headings : Clustered Regularly Interspaced Short Palindromic Repeats; Gene Deletion; Genome, Bacterial; Homeostasis; Homologous Recombination; Streptococcus thermophilus / genetics; Streptococcus thermophilus / growth & development
TL;DR: This study shows that CRISPR-Cas systems can be directed to target and delete genomic islands that are flanked by insertion-sequence elements and devoid of essential genes, and established that self-targeting CRISpr-cas systems may direct significant evolution of bacterial genomes on a population level, influencing genome homeostasis and remodeling. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

CRISPR Immunity Drives Rapid Phage Genome Evolution in Streptococcus thermophilus

MBIO, 6(2).

MeSH headings : Adaptation, Biological; CRISPR-Cas Systems; Evolution, Molecular; Genome, Viral; Host-Parasite Interactions; Mutation Rate; Polymorphism, Single Nucleotide; Recombination, Genetic; Streptococcus thermophilus / genetics; Streptococcus thermophilus / virology
TL;DR: CRISPR immunity drives the accumulation of phage genome rearrangements (which enable longer phage survival) and escape mutations, establishing CRISPR as one of the fundamental drivers of phages evolution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Stability and immunogenicity of hypoallergenic peanut protein-polyphenol complexes during in vitro pepsin digestion

FOOD & FUNCTION, 6(7), 2145–2154.

By: N. Plundrich n, B. White, L. Dean, J. Davis, E. Foegeding n & M. Lila n

MeSH headings : Antigens, Plant / chemistry; Antigens, Plant / immunology; Arachis / chemistry; Arachis / immunology; Digestion; Pepsin A / chemistry; Plant Proteins / chemistry; Plant Proteins / immunology; Polyphenols / chemistry; Polyphenols / immunology
TL;DR: It is suggested that peanut protein-polyphenol complexes may be less immunoreactive passing through the digestive tract in vivo, contributing to their attenuated allergenicity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis

EMBO JOURNAL, 34(7), 881–895.

By: Y. Lightfoot*, K. Selle n, T. Yang*, Y. Goh n, B. Sahay*, M. Zadeh*, J. Owen*, N. Colliou* ...

author keywords: colitis; immune regulation; Lactobacillus acidophilus; SIGNR3; surface layer protein A
MeSH headings : Animals; Antigens, CD / genetics; Antigens, CD / immunology; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Inflammatory Bowel Diseases / genetics; Inflammatory Bowel Diseases / immunology; Inflammatory Bowel Diseases / microbiology; Inflammatory Bowel Diseases / pathology; Intestinal Mucosa / immunology; Intestinal Mucosa / pathology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / immunology; Lectins, C-Type / genetics; Lectins, C-Type / immunology; Lipopolysaccharides / genetics; Lipopolysaccharides / immunology; Mice; Mice, Knockout; Protein Binding / genetics; Protein Binding / immunology; Teichoic Acids / genetics; Teichoic Acids / immunology
TL;DR: This work presents critical insights into SlpA/SIGNR3‐induced responses that are integral to the potential development of novel biological therapies for autoinflammatory diseases, including IBD. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Using State Diagrams for Predicting Colloidal Stability of Whey Protein Beverages

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 63(17), 4335–4344.

By: T. Wagoner n, L. Ward & E. Foegeding n

author keywords: whey protein isolate; stability; heat treatment; beverage; solubility; turbidity
MeSH headings : Animals; Beverages / analysis; Cattle; Colloids / chemistry; Hot Temperature; Hydrogen-Ion Concentration; Lactalbumin / chemistry; Lactoglobulins / chemistry; Milk Proteins / chemistry; Protein Aggregates; Serum Albumin, Bovine / chemistry; Solubility; Whey Proteins
TL;DR: The results indicate that combinations of state diagrams can be used to identify key regions of stability for whey protein containing beverages. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium

PLOS ONE, 10(7).

Ed(s): C. Riedel

MeSH headings : Bifidobacterium / genetics; CRISPR-Cas Systems / genetics; Chromosomes, Bacterial / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; DNA / genetics; Evolution, Molecular; Genetic Variation / genetics; Genome, Bacterial / genetics; Prophages / genetics
TL;DR: It is found that many Bifidobacterium species have unusually large and diverse CRISPR-Cas systems that contain spacer sequences showing homology to foreign genetic elements like prophages, which may shed light on evolutionary processes and strain divergence. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Identifying Key Attributes for Protein Beverages

JOURNAL OF FOOD SCIENCE, 80(6), S1383–S1390.

By: A. Oltman n, K. Lopetcharat, E. Bastian & M. Drake n

author keywords: conjoint; consumer preference; Kano; priming; protein beverages
MeSH headings : Adult; Beverages; Choice Behavior; Consumer Behavior; Dietary Carbohydrates; Dietary Proteins / chemistry; Female; Flavoring Agents; Food Preferences; Food Technology; Humans; Male; Middle Aged; Nigeria; Sweetening Agents / chemistry; Taste; Whey Proteins; Young Adult
TL;DR: An adaptive choice-based conjoint study was conducted along with Kano analysis to gain insight on protein beverage consumers and evaluated effects of priming on liking of protein beverages, finding that protein beverages must have desirable flavor for wide consumer appeal. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Controlling Listeria monocytogenes in Cold Smoked Salmon with the Antimicrobial Peptide Salmine

JOURNAL OF FOOD SCIENCE, 80(6), M1314–M1318.

By: C. Cheng n, F. Arritt n & C. Stevenson n

author keywords: antimicrobial; Listeria monocytogenes; salmon; smoked
MeSH headings : Animals; Anti-Infective Agents / pharmacology; Colony Count, Microbial; Food Handling / methods; Food Microbiology; Food Preservation / methods; Humans; Listeria monocytogenes / drug effects; Peptides / pharmacology; Salmine / pharmacology; Salmon / microbiology; Salts; Seafood / microbiology; Smoke
TL;DR: There is potential for salmine to be used as a natural hurdle to inhibit growth of LM due to post process contamination; however, future investigations for extending this effect throughout the shelf life of smoked salmon products are warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

NUCLEIC ACIDS RESEARCH, 43(7), 3407–3419.

By: R. Barrangou n, A. Birmingham, S. Wiemann*, R. Beijersbergen*, V. Hornung* & A. Smith

MeSH headings : Animals; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Genetic Engineering; Genome; RNA Interference
TL;DR: How the history of RNAi can inform today's challenges in CRISPR-Cas9 genome engineering such as efficiency, specificity, high-throughput screening and delivery for in vivo and therapeutic applications is examined. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 article

Unraveling the potential of CRISPR-Cas9 for gene therapy

Barrangou, R., & May, A. P. (2015, March). EXPERT OPINION ON BIOLOGICAL THERAPY, Vol. 15, pp. 311–314.

author keywords: Cas9; CRISPR; gene therapy; genome editing
MeSH headings : Animals; CRISPR-Cas Systems / genetics; DNA Repair / genetics; Genetic Therapy / methods; Genetic Therapy / trends; Genome; Humans
TL;DR: The molecular machinery from the prokaryotic clustered regularly interspaced short palindromic repeats (CRISPR)-Cas immune system has broadly been repurposed for genome editing in eukaryotes and has opened new avenues for the investigation of genetic diseases in general, and for gene therapy applications in particular. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 review

The roles of CRISPR-Cas systems in adaptive immunity and beyond

[Review of ]. CURRENT OPINION IN IMMUNOLOGY, 32, 36–41.

By: R. Barrangou n

MeSH headings : Archaea / immunology; Bacteria / immunology; Bacterial Physiological Phenomena; Biological Evolution; CRISPR-Cas Systems / physiology; Gene Expression Regulation, Bacterial; Genome, Bacterial; Transcription, Genetic
TL;DR: Though the primary established role of CRISPR-Cas systems is in bona fide adaptive antiviral defense in bacteria, a growing body of evidence indicates that it also plays critical functional roles beyond immunity, such as endogenous transcriptional control. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Electromyographic Evaluation of Masticatory Muscles in Dentate Patients Versus Conventional and Implant-Supported Fixed and Removable Denture Wearers- A Preliminary Report Comparing Model Foods

INTERNATIONAL JOURNAL OF PROSTHODONTICS, 28(1), 79–92.

By: S. Uram-Tuculescu*, L. Cooper, E. Foegeding n, C. Vinyard*, I. De Kok & G. Essick

MeSH headings : Agar / chemistry; Aged; Aged, 80 and over; Area Under Curve; Biomechanical Phenomena; Case-Control Studies; Dental Prosthesis, Implant-Supported; Dentition; Denture, Complete; Denture, Complete, Lower; Denture, Complete, Upper; Denture, Overlay; Electromyography / methods; Female; Food; Humans; Male; Masseter Muscle / physiology; Mastication / physiology; Masticatory Muscles / physiology; Middle Aged; Neck Muscles / physiology; Stress, Mechanical; Temporal Muscle / physiology; Time Factors
TL;DR: The observed increases in relative masticatory muscle activity for denture wearers compared to the dentate subjects during oral food processing likely reflect supplemental mechanical efforts to accommodate the use of dentures for preparing a bolus for swallowing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

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